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    题名 作者 年代 出处 被引量
1Molecular approaches to study the insect gut symbiotic microbiota at the 'omics' age显示文摘Weibing Shi Ryan Syrenne Jian-Zhong Sun Joshua S. Yuan 2010Insect Science2010,17,3:17
2Control of Rice Embryo Development, Shoot Apical Meristem Maintenance, and Grain Yield by a Novel Cytochrome P450显示文摘被子植物种子通常由二主要部分组成:胚胎和内乳。然而,分子的机制 underlyingembryo 和内乳发展仍然保持大部分未知,特别地在米饭,模型谷物。这里,我们报导 identificationand 米饭巨人胚胎(GE ) 基因的功能的描述。GE 的变化在种子导致了一个大胚胎,它被胚鳞房间的过多的扩大引起。embryonic 以后 growthof ge 幼苗严重地由于有缺点的射击被禁止顶端的分裂组织(SAM ) 维护。基于地图的克隆表明 thatGE 编码对 endoplasmic 蜂窝胃局部性的 CYP78A 亚科 P450 monooxygenase。GE 在 scutellar 上皮主要被表示,在胚胎和内乳之间的接口区域。Overexpressionof GE 支持了细胞增长并且提高了米饭植物生长和谷物产量,但是减少了胚胎尺寸,建议 GE 为协调米饭胚胎和内乳开发是批评的。而且,转基因的 Arabidopsis 植物 overexpressing AtCYP78A10,一个 GE 相当或相同的事物,也生产的更大的种子,在一起调整种子 development.Taken 为 P450s 的 CYP78A 亚科暗示一个保存角色,我们的结果显示 GE 在调整胚胎发展和 SAM maintenance.Key 词起关键作用:Weibing Yang Mingjun Gao Xin Yin Jiyun Liu Yonghan Xu Longjun Zeng Qun Li Shubiao Zhang Junmin Wang Xiaoming Zhang Zuhua He 2013Molecular Plant2013,6,6:16
3m^6A-dependent biogenesis of circular RNAs in male germ cells显示文摘The majority of circular RNAs(circRNAs)spliced from coding genes contain open reading frames(ORFs)and thus,have protein coding potential.However,it remains unknown what regulates the biogenesis of these ORF-containing circRNAs,whether they are actually translated into proteins and what functions they play in specific physiological contexts.Here,we report that a large number of circRNAs are synthesized with increasing abundance when late pachytene spermatocytes develop into round and then elongating spermatids during murine spermatogenesis.For a subset of circRNAs,the back splicing appears to occur mostly at m^6A-enriched sites,which are usually located around the start and stop codons in linear mRNAs.Consequently,approximately a half of these male germ cell circRNAs contain large ORFs with m^6A-modified start codons in their junctions,features that have been recently shown to be associated with protein-coding potential.Hundreds of peptides encoded by the junction sequences of these circRNAs were detected using liquid chromatography coupled with mass spectrometry,suggesting that these circRNAs can indeed be translated into proteins in both developing(spermatocytes and spermatids)and mature(spermatozoa)male germ cells.The present study discovered not only a novel role of m^6A in the biogenesis of coding circRNAs,but also a potential mechanism to ensure stable and long-lasting protein production in the absence of linear mRNAs,i.e.,through production of circRNAs containing large ORFs and m^6A-modified start codons in junction sequences.Chong Tang Yeming Xie Tian Yu Na Liu Zhuqing Wang Rebekah J.Woolsey Yunge Tang Xinzong Zhang Weibing Qin Ying Zhang Ge Song Weiwei Zheng Juan Wang Weitian Chen Xiongyi Wei Zhe Xie Rachel Klukovich Huili Zheng David R.Quilici Wei Yan 2020Cell Research2020,30,3:12
4Simulation research on the influence of eroded primary key strata on dynamic strata pressure of shallow coal seams in gully terrain显示文摘In Huojitu Coal Mine of Shendong mining area, the dynamic strata pressure (DSP) accidents occurred when the working faces passed the gully terrain. Focusing on this problem, we used physical simulation experimental method to thoroughly study the influence of eroded overlying primary key strata (PKS) in the gully terrain on DSP of shallow coal seams in this paper. The result show that when mining activities took place in the uphill section of shallow coal seams in gully terrain and the PKS were eroded, the blocks could not form stable bond-beam structures since the horizontal force of PKS blocks in adjacent sloping surfaces were relatively small. The sliding instability of blocks caused rapid increase of the load on the sub-key strata (SKS) blocks, which resulted into coal slide and roof fall as well as sharp drop of active columns. This led to DSP phenomenon. When the PKS blocks were intact, there was no DSP phenomenon to enable blocks provide certain horizontal force to maintain stable bond-beam structure. The simulation results were verified by the mining practices of working face 21306 crossing the gully terrain in the Huojitu Coal Mine.Zhang Zhiqiang Xu Jialin Zhu Weibing Shan Zhenjun 2012International Journal of Mining Science and Technology2012,22,1:12
5Numerical Simulation of Nonlinear Three-Dimensional Waves in Water of Arbitrary Varying Topography显示文摘—The numerical simulation is based on the authors'high-order models with a dissipative termfor nonlinear and dispersive wave in water of varying depth.Corresponding finite-difference equations andgeneral conditions for open and fixed natural boundaries with an arbitrary reflection coefficient and phaseshift are also given in this paper.The systematical tests of numerical simulation show that the theoreticalmodels,the finite-difference algorithms and the boundary conditions can give good calculation results forthe wave propagating in shallow and deep water with an arbitrary slope varying from gentle to steep.Hong, Guangwen Zhang, Hongsheng Feng, Weibing 1998China Ocean Engineering1998,13,4:10
6Roof pre-blasting to prevent support crushing and water inrush accidents显示文摘Support crushing and water inrush when mining under an unconsolidated confined aquifer in the Qidong Coal Mine was prevented by roof pre-blasting. The mechanism and applicable conditions for this method have been studied. The results show that when an overburden structure that may cause support crushing and a water inrush accident exists the weakening of the primary key stratum, which thereby reduces its weighting step, roof pre-blasting is both feasible and effective. If the position of the primary key stratum can be moved upward to exceed 10 times the mining height the possibility of support crushing and water inrush disaster caused by key stratum compound breakage will be lowered. The overburden structure of the number 7121 working face was considered during the design of a technical proposal involving roof pre-blasting. After comprehensively analyzing the applicability of roof pre-blasting the resulting design prevented support crushing and water inrush disasters from happening at the number 7121 working face and laid a solid foundation for mining safely.Wang Xiaozhen 2012International Journal of Mining Science and Technology2012,22,3:10
7A DELLA protein complex controls the arbuscular mycorrhizal symbiosis in plants显示文摘Nan Yu Dexian Luo Xiaowei Zhang Junzhong Liu Wanxiao Wang Yue Jin Wentao Dong Jiyun Liu Huan Liu Weibing Yang Longjun Zeng Qun Li Zuhua He Giles E D Oldroyd Ertao Wang 2014Cell Research2014,24,1:9
8Optimal Design for an End Face Engagement Worm Gear with Multiple Worm-wheel Meshing显示文摘To solve the problem for lacking a special mechanical transmission that could provide multiple outputs with high transmission efficiency and good lubrication in the modern industrial, a novel worm gear, named end face engagement worm gear, with multiple worm-wheel meshing is proposed for the first time. The essential parameters for the worm gear are optimized to enhance lubrication and meshing properties. Moreover, analysis of variance(ANOVA) is applied to determine the optimum levels and to determine the influence of parameters. The ANOVA results show that the novel end face engagement worm gear with multiple worm wheels provides high lubrication(the lubrication angle is more than 89°) and meshing performance(the induce normal curvature is less than 0.0002 mm^(-1)). The interaction between center distance and roller slant distance most strongly influences the lubrication angle(contributed 51.6%), followed by the parameters of center distance(contributed 25.0%), roller slant distance(contributed 16.4%), tooth angle of gear, gear ratio, and roller radius. In addition, roller radius most strongly influences the induced normal curvature(contributed 39.4%), followed by roller slant distance(contributed 15.2%), tooth angle of the gear(contributed 9.0%), center distance, and gear ratio. The proposed worm gear helps to enrich the no-backlash high precision worm drive and the optimal design method can provide a useful reference on performance improvement of other worm gear.DENG Xingqiao ZHU Weibing CHEN Yonghong CHEN Shouan WANG Jinge 2017Chinese Journal of Mechanical Engineering2017,30,1:9
9An adaptive path selection model for WSN multipath routing inspired by metabolism behaviors显示文摘In multipath routing of wireless sensor network(WSN), greedy path selection is always prone to cause path oscillation(frequent path changes) between each couple of sensor and sink nodes. To alleviate the side effect, we propose an adaptive path selection model(called a WSN path selection model based on the adaptive response by attractor selection(ARAS) model(WARAS)) inspired by metabolism behaviors of Escherichia Coli.The model consists of two main features. The first one is a new formula for a parameter called path-activity used to indicate adaptation goodness of multipath traffic transmission in dynamic network environments, which is inversely proportional to absolute value of difference between current path quality and best path quality.The second one is a novel attractor expression for attractors of multi-attractor equations to concretely specify stochastic effect of noise items in the equations on the path selection. Then, in an experimental WSN scenario composed of many source nodes and their shared neighbor nodes, we validate a dynamic-adaptive selection characteristic of the WARAS on distributing loads of the neighbor nodes. Subsequently, we design a path quality probe scheme in a multipath ad hoc on-demand distance vector routing(AODV) protocol. Compared with the greedy path selection through the path quality probe scheme, simulation results show the WARAS can perform better on reducing network delay and the path oscillation.GONG WeiBing YANG XiaoLong ZHANG Min LONG KePing 2015Science China(Information Sciences)2015,58,10:8
10Limit analysis on seismic stability of anisotropic and nonhomogeneous slopes with anti-slide piles显示文摘This study employs the limit analysis method to evaluate the seismic stability of anisotropic and nonhomogeneous slopes stabilized with anti-slide piles. The pseudo-static approach is used to simplify the earthquake load. The yield seismic acceleration factor is obtained from the optimization procedure and the results are verified with the published data. Then, the seismically-unstable slope is reinforced with anti-slide piles, and the seismic stability of the reinforced slope is explored. The results show that the anisotropy and nonhomogeneity of soils have significant effects on the stabilizing force required from the anti-slide piles and the optimal location of the pile is near the toe of the slope.GONG WeiBing LI JingPei LI Lin 2018Science China(Technological Sciences)2018,61,1:7
11Characterization and mapping of a novel mutant sms1 (senescence and male sterility 1) in rice显示文摘Plant senescence plays diverse important roles in development and environmental responses.However,the molecular basis of plant senescence is remained largely unknown.A rice spontaneous mutant with the character of early senescence and male sterility (sms) was found in the breeding line NT10-748.In order to identify the gene SMS1 and the underlying mechanism,we preliminarily analyzed physiological and biochemical phenotypes of the mutant.The mutant contained lower chlorophyll content compared with the wild type control and was severe male sterile with lower pollen viability.Genetic analysis showed that the mutant was controlled by a single recessive gene.By the map-based cloning approach,we fine-mapped SMS1 to a 67 kb region between the markers Z3-4 and Z1-1 on chromosome 8 using 1,074 F2 recessive plants derived from the cross between the mutant sms1 (japonica) × Zhenshan 97 (indica),where no known gene involved in senescence or male sterility has been identified.Therefore the SMS1 gene will be a novel gene that regulates the two developmental processes.The further cloning and functional analysis of the SMS1 gene is under way.Wenyi Yan Shenghai Ye Qingsheng Jin Longjun Zeng Yu Peng Dawei Yan Weibing Yang Donglei Yang Zuhua He Yanjun Dong Xiaoming Zhang 2010Journal of Genetics and Genomics2010,37,1:6
12Pinless Friction Stir Welding of AA2024-T3Joint and Its Failure Modes显示文摘The joining of aluminum alloy sheets with thickness less than 2.0 mm is difficult via conventional frictionstir welding owing to the defects in the joint, such as root flaw, keyhole and lazy S. In the present research, a newlydesigned pinless tool with involute grooves on its shoulder surface was applied to weld 1.5 mm thick AA2024-T3. Theeffects of the rotating speed and welding speed on the microstructure and mechanical properties of the joints were analyzed.The experimental results showed that the root flaw and keyhole were successfully eliminated. The lazy S wasalso eliminated under the optimized welding parameters. The maximum tensile strength of the joints was 326 MPa,which is about 74.1% that of the base material. Moreover, all the tensile samples fractured from the retreating side.Two fracture modes were observed during the tensile tests, which are related with the lazy S.Li Wenya Li Jinfeng Zhang Zhihan Gao Dalu Wang Weibing Luan Guohong 2014Transactions of Tianjin University2014,20,6:6
13Three‑Dimensional Ordered Mesoporous Carbon Spheres Modified with Ultrafine Zinc Oxide Nanoparticles for Enhanced Microwave Absorption Properties显示文摘Currently,electromagnetic radiation and interference have a significant effect on the operation of electronic devices and human health systems.Thus,developing excellent microwave absorbers have a huge significance in the material research field.Herein,a kind of ultrafine zinc oxide(ZnO)nanoparticles(NPs)supported on three-dimensional(3D)ordered mesoporous carbon spheres(ZnO/OMCS)is prepared from silica inverse opal by using phenolic resol precursor as carbon source.The prepared lightweight ZnO/OMCS nanocomposites exhibit 3D ordered carbon sphere array and highly dispersed ultrafine ZnO NPs on the mesoporous cell walls of carbon spheres.ZnO/OMCS-30 shows microwave absorbing ability with a strong absorption(−39.3 dB at 10.4 GHz with a small thickness of 2 mm)and a broad effective absorption bandwidth(9.1 GHz).The outstanding microwave absorbing ability benefits to the well-dispersed ultrafine ZnO NPs and the 3D ordered mesoporous carbon spheres structure.This work opened up a unique way for developing lightweight and high-efficient carbon-based microwave absorbing materials.Yan Song Fuxing Yin Chengwei Zhang Weibing Guo Liying Han Ye Yuan 2021Nano-Micro Letters2021,13,5:6
14Hepatitis B Virus X Protein-Induced Aberrant Epigenetic Modifications Contributing to Human Hepatocellular Carcinoma Pathogenesis显示文摘Yi Tian Weibing Yang Jianxun Song Yuzhang Wu Bing Ni 2013Molecular and Cellular Biology2013,,15:6
15Establishment and validation of standardized animal models of spinal cord injury by normal external force-caused fracture dislocation显示文摘The duplication of animal models plays a key role in spinal cord injury research; however, there has been limited study into normal, external force-derived fracture dislocation. This study adopted experimental devices, designed in-house, to construct standardized ventral and dorsal spinal cord injury animal models of 6 g and 17 g falling from a height of 2, 4, and 10 cm, and 15, 30 or 50 g transversal compression on the spinal cord. The results showed that gradual increases in the degree of histopathological injury led to decreased Tarlov and Basso, Beattie and Bresnahan scores for the behavioral test, and increased Ashworth scores for the hind limb. Furthermore, there was a gradual decline in the slope test in the rats with dorsal spinal cord injury that correlated to increases in the falling substance weight or falling height. Similar alterations were observed in the ventral spinal cord injured rats, proportional to the increase in compression weight. Our experimental findings indicate that the standardized experimental rat models of dorsal and ventral spinal cord injury are stable, reliable and reproducible.Weibing Shuang Qiang Liu Shoubin Jiao Yang Yang 2011Neural Regeneration Research2011,6,35:6
16Tat-functionalized Ag-Fe_3O_4 nano-composites as tissue-penetrating vehicles for tumor magnetic targeting and drug delivery显示文摘In this paper, we prepared a dual functional system based on dextrin-coated silver nanoparticles which were further attached with iron oxide nanoparticles and cell penetrating peptide(Tat), producing Tat-modified Ag-Fe_3O_4 nanocomposites(Tat-FeAgNPs). To load drugs, an –SH containing linker, 3-mercaptopropanohydrazide, was designed and synthesized. It enabled the silver carriers to load and release doxorubicin(Dox) in a pH-sensitive pattern. The delivery efficiency of this system was assessed in vitro using MCF-7 cells, and in vivo using null BalB/c mice bearing MCF-7 xenograft tumors. Our results demonstrated that both Tat and externally applied magnetic field could promote cellular uptake and consequently the cytotoxicity of doxorubicin-loaded nanoparticles,with the IC_(50) of Tat-FeAgNP-Dox to be 0.63 mmol/L. The in vivo delivery efficiency of Tat-FeAgNP carrying Cy5 to the mouse tumor was analyzed using the in vivo optical imaging tests, in which TatFeAgNP-Cy5 yielded the most efficient accumulation in the tumor(6.772.4% ID of Tat-FeAgNPs).Anti-tumor assessment also demonstrated that Tat-FeAgNP-Dox displayed the most significant tumor-inhibiting effects and reduced the specific growth rate of tumor by 29.6%(P ? 0.009), which could be attributed to its superior performance in tumor drug delivery in comparison with the control nanovehicles.Ergang Liu Meng Zhang Hui Cui Junbo Gong Yongzhuo Huang Jianxin Wang Yanna Cui Weibing Dong Lu Sun Huining He Victor C.Yang 2018Acta Pharmaceutica Sinica B2018,8,6:5
17Toward emerging gallium oxide semiconductors:A roadmap显示文摘Owing to the advantages of ultra-wide bandgap and rich material systems,gallium oxide(Ga_(2)O_(3))has emerged as a highly viable semiconductor material for new researches.This article mainly focuses on the growth processes,material characteristics,and applications of Ga_(2)O_(3).Compared with single crystals and the epitaxial growth of other wide-bandgap semiconductors,large-size and high-quality��-Ga_(2)O_(3) single crystals can be efficiently grown with a low cost,making them highly competitive.Thanks to the availability of high-quality single crystals,epi-taxial films,and rich material systems,high-performance semiconductor devices based on Ga_(2)O_(3) go through a booming development in recent years.The defects and interfaces of Ga_(2)O_(3) are comprehensively analyzed owing to their significant influence on practical applications.In this study,the two most common applications of Ga_(2)O_(3) materials are introduced.The high breakdown electric field,high working temperature,and excellent Baliga’s figure-of-merit of Ga_(2)O_(3) represent an inspiring prospect for power electronic devices.In addition,the excellent absorption in deep-ultraviolet band provides new ideas for optoelectronic detectors and ensures the dramatic progress.Finally,the summary,challenges,and prospects of the Ga_(2)O_(3) materials and devices are presented and discussed.Yuan Yuan Weibing Hao Wenxiang Mu Zhengpeng Wang Xuanhu Chen Qi Liu Guangwei Xu Chenlu Wang Hong Zhou Yanni Zou Xiaolong Zhao Zhitai Jia Jiandong Ye Jincheng Zhang Shibing Long Xutang Tao Rong Zhang Yue Hao 2021Fundamental Research2021,1,6:5
18Turbidity maximum formation and its seasonal variations in the Zhujiang(Pearl River)Estuary,southern China显示文摘Real-time observations in the field and numerical simulations(with Delft3D) were combined to study the formation, distribution and the relevant influencing factors of turbidity maximum(TM) in the Zhujiang(Pearl River) Estuary(ZE). The spatial distribution pattern of the TM varies with the longitudinal distributions of salinity and suspended sediment concentration(SSC). The SSC is enhanced and the TM is intensified during dry seasons,whereas the center of the TM moves upstream by a distance of 10 km during wet seasons. The formation of the TM is influenced by a complex combination of numerous factors, including tides, river discharges and topography, wherein sediment resuspension and vertical circulation dominate the formations and variability of the TM.LIU Runqi WANG Yaping GAO Jianhua WU Ziyin GUAN Weibing 2016Acta Oceanologica Sinica2016,35,8:5
19Bridge Continuous Deformation Measurement Technology Based on Fiber Optic Gyro显示文摘桥牌是现代交通系统的重要部分,变丑是为桥安全评估的一个关键索引。为了完成长跨度桥,很快弄弯测量并且及时并且精确地定位桥最大值变丑,连续变丑测量系统(CDMS ) 在这基于惯性的站台被介绍并且验证纸。第一基于各种各样的桥变丑测量方法,变丑测量的方法基于纤维,眼的旋转罗盘(雾) 被介绍。第二,基本测量原则基于雾被介绍,连续曲线轨道被公式导出。然后,测量精确性在理论被分析,相关因素被介绍保证测量精确性。最后,变丑测量实验越过长江在一座桥上被进行。试验性的结果证明介绍变丑测量方法可行、实际、可靠;系统能精确地并且快速定位最大的变丑并且有广泛、宽广的应用程序前景。Weibing GAN Wenbin HU Fang LIU Jianguang TANG Sheng LI Yan YANG 2016Photonic Sensors2016,6,1:4
20Printed stretchable circuit on soft elastic substrate for wearable application显示文摘In this paper, a flexible and stretchable circuit has been fabricated by the printing method based on Ag NWs/PDMS composite. The randomly oriented Ag NWs were buried in PDMS to form a conductive and stretchable electrode. Stable conductivity was achieved with a large range of tensile strain(0-50%) after the initial stretching/releasing cycle. The stable electrical response is due to the buckling of the Ag NWs/PDMS composite layer. Furthermore, printed stretchable circuits integrated with commercial ICs have been demonstrated for wearable applications.Wei Yuan Xinzhou Wu Weibing Gu Jian Lin Zheng Cui 2018Journal of Semiconductors2018,39,1:4
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