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| 1 | Defensin expression in chronic pouchitis in patients with ulcerative colitis or familial adenomatous polyposis coli显示文摘瞄准:当在在为家庭腺瘤息肉病关口 i (FAP ) 的 proctocolectomy 以后的病人是稀罕的时, Pouchitis 在小袋外科以后在开始的 10 年期间与 ulcerative 在多达 50% 病人在 ileoanal 小袋发展症候群。Defensins 是天生的免疫系统的主要部件并且在胃肠的微生物引起的动态平衡起一个重要作用。小袋 defensin 和 cytokine 表示与小袋发炎的状态被相关在 pouchitis 学习他们的角色。方法:有 ulcerative 和 FAP 症候群的病人在外科以后与小袋被成层进组,小袋没有或与 pouchitis。从从健康的肠或从有 ulcerative 的病人的正常终端回肠的终端回肠的活体检视用作控制。从小袋和控制的 mRNA 为 defensin 和 cytokine 表示被分析。结果:defensins 的表示在外科以后立即在所有小袋被增加,与控制的回肠相比。开始,在 ulcerative 的小袋比 FAP 小袋揭示了更高的 defensin 表示。Defensin 表示在两个耐心的组衰退了并且与 ulcerative 在病人在 pouchitis 稍微再增加了。没有 pouchitis 的 FAP 小袋有 beta-defensin hBD-1 的强壮的表示,当所有另外的 defensins 在底层留下了时。在 ulcerative 小袋的 Cytokine 表示高,当 FAP 小袋仅仅在外科以后显示出中等提高的 cytokines 时。结论:pouchitis 的开发除了 cytokines 的高表示在 ulcerative 与减少的 defensin 表示相关。在 FAP 小袋的 pouchitis 的低发生与低 cytokine 层次联合与 hBD-1 beta-defensin 的增加的表示相关。 | Karlheinz Kiehne Gabriele Brunke Franziska Wegner Tomas Banasiewicz Ulrich R F lsch Karl-Heinz Herzig | 2006 | World Journal of Gastroenterology2006，12，7： | 8 |
| 2 | Interleukin-6,procalcitonin and TNF-alpha:markers of peri-prosthetic infection fol owing total joint replacement显示文摘 | Bottner F Wegner A Winkelmann W | | 0，，01： | 1 |
| 3 | Lack of HIF-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signaling显示文摘 | Javorina M Maisel M Wegner F | | 0，，： | 1 |
| 4 | Muhipotent neural stem cells from the adult tegmentum with dopaminergic potential develop essential properties of functional neurons显示文摘 | Hermann A Maisel M Wegner F | 2006 | Stem Cells2006，24，4： | 1 |
| 5 | Interleukinb,procalcitonin and TNF- ct markers of periprosthetic infection following total joint replacement显示文摘 | Botyber F Wegner A Winkelmann W | 2007 | J Bone Joint Surg Br2007，89，1： | 1 |
| 6 | Amplified spontaneous emission in optically pumped neat films of a polyfluorene derivative显示文摘 | Li J Y Laquai F Wegner G | 2009 | Chem Phys Lett2009，478，： | 1 |
| 7 | Interleukin-6, pro-calcitonin and TNF -alpha: markers of peri-prosthetic infectionfollowing total joint replacement显示文摘 | Bottner F Wegner A Winkelmann W | 2007 | J Bone Joint Surg Br2007，89，1： | 1 |
| 8 | Growthand breed-related changes of marbling characteristics in cattle显示文摘 | Albrecht E F Teuscher K E Wegner J | 2006 | Anim Sci2006，84，： | 1 |
| 9 | Interleukin-6,procalcitonin and TNF-α markers of peri-prosthetic infection following total joint replacement显示文摘 | BOTTBER F WEGNER A WINKELMANN W | 2007 | J Bone Joint Surg Br2007，89，1： | 1 |
| 10 | Interleukin-6, procalcitonin and TNF-alpha: markers of peri-prosthetic infection following total joint replacement显示文摘 | Bottner F Wegner A Winkelmann W | 2007 | J Bone Joint Surg Br2007，89，： | 1 |
| 11 | Lack of HIF-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signaling 显示文摘 | Javorina M Maisel M Wegner F | 2007 | J Neurosci2007，27，2： | 1 |
| 12 | Movements by birds and small mammals between a wood and adjoining farmland habitats显示文摘 | Wegner J F Merriam G | 1979 | Journal of Applied Ecology1979，，16： | 1 |
| 13 | Growth and breed-relat?ed changes of marbling characteristics in cattle显示文摘 | Albrecht E F Teuscher K E Wegner J | 2006 | Anim Sci2006，84，： | 1 |
| 14 | Muhipotent neu- ral stem cells from the adult tegmentum with dopaminergic potential develop essential properties of functional neurons 显示文摘 | Hermann A Maisel M Wegner F | 2006 | Stem Cells2006，24，： | 1 |
| 15 | Transcranial ultrasound to detect elevated intracranial pressure: comparison of septum pellucidum undulations and optic nerve sheath diamete显示文摘 | Bolesch S von Wegner F Senft C | 2015 | Ultrasound Med Biol2015，41，： | 1 |
| 16 | Biological Treatments as an Alternative to Chemical Pretreatments in High-Yield Wood Pulping显示文摘 | Wegner T H Myers G C Leatham G F | 1991 | Tappi J1991，74，3： | 1 |
| 17 | Interleukin 6, procalcitonin and TNF-alpha: markers of peri-prosthetic infection following total joint replacement显示文摘 | Bottner F Wegner A Winkelmann W | 2007 | J Bone Joint Surg Br2007，89，1： | 1 |
| 18 | Biomechanical pulping of aspen chips: paper strength and optical properties resulting from different fungal treatments 显示文摘 | Leatham G F Myers G C Wegner T H | 1990 | Tappi J1990，73，3： | 1 |
| 19 | Anti-leucine rich glioma inactiva- ted 1 protein and anti-N-methyl-D-aspartate receptor encephalitis show distinct patterns of brain glucose metabolism in 18F-fluoro-2-de- oxy-d-glucose positron emission tomography 显示文摘 | Wegner F Wilke F Raab P | 2014 | BMC Neurol2014，20，14： | 1 |
| 20 | Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels,inflam- matory demyelination and acute axonal damage in mice with experi- mental autoimmune encephalomyelitis 显示文摘 | Wegner C Stadelmann C F'fsrmer R | 2010 | Journal of Neumimmunol- ogy2010，227，12： | 1 |
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