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| 1 | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway显示文摘 | Youjun Li Hao Zhou Fengzhi Li Siew Wee Chan Zhijie Lin Zhiyi Wei Zhou Yang Fusheng Guo Chun Jye Lim Wancai Xing Yuequan Shen Wanjin Hong Jiafu Long Mingjie Zhang | 2015 | Cell Research2015，25，7： | 9 |
| 2 | Experimental Studies on The Mechanism and Control of Secondary Flow Losses in Turbine Cascades显示文摘This paper summarizes the results of the authors' 4 year experimental studies on the secondary flow losses in turbine cascades.cascade wind tunnel experiments were carried out concerning the influence of aspect rations,incidence,turning angles and outer endwall divergent angles in order to unveil the evolution mechanism of secondary flow losses in turbine cascades without end clearance.Some methods for controlling the secondary flows are investigated including the blade leaning,blade cambering,endwall convergence and leading edge extension at two ends of the blade. | Wang Zhongqi Han Wanjin Xu Wenyuan Harbin Institute of Technology | 1992 | Journal of Thermal Science1992，1，3： | 7 |
| 3 | Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1显示文摘Multisystem manifestations in myotonic dystrophy type 1(DM1)may be due to dosage reduction in multiple genes induced by aberrant expansion of CTG repeats in DMPK,including DMPK,its neighboring genes(SIX5 or DMWD)and downstream MBNLh However,direct evidence is lacking.Here,we develop a new strategy to generate mice carrying multigene heterozygous mutations to mimic dosage reduction in one step by injection of haploid embryonic stem cells with mutant Dmpk,Six5 and Mbnll into oocytes.The triple heterozygous mutant mice exhibit adult-onset DM1 phenotypes.With the additional mutation in Dmwd,the quadruple heterozygous mutant mice recapitulate many major manifestations in congenital DM1.Moreover,muscle stem cells in both models display reduced sternness,providing a unique model for screening small molecules for treatment of DM1.Our results suggest that the complex symptoms of DM1 result from the reduced dosage of multiple genes. | Qi Yin Hongye Wang Na Li Yifu Ding Zhenfei Xie Lifang Jin Yan Li Qiong Wang Xinyi Liu Liuqing Xu Qing Li Yongjian Ma Yanbo Cheng Kai Wang Cuiqing Zhong Qian Yu Wei Tang Wanjin Chen Wenjun Yang Fan Zhang Chen Ding Lan Bao Bin Zhou Ping Hu Jinsong Li | 2020 | Cell Research2020，30，2： | 7 |
| 4 | Human CD34loCD133lo fetal liver cells support the expansion of human CD34hiCD133hi hematopoietic stem cells显示文摘 | Kylie Su Mei Yong Choong Tat Keng Shu Qi Tan Eva Loh Kenneth TE Chang Thiam Chye Tan Wanjin Hong Qingfeng Chen | 2016 | Cellular & Molecular Immunology2016，13，5： | 5 |
| 5 | Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis显示文摘 | Lin He Xinhua Liu Jianguo Yang Wanjin Li Shumeng Liu Xujun Liu Ziran Yang Jie Ren Yue Wang Lin Shan Chengjian Guan Fei Pei Liandi Lei Yu Zhang Xia Yi Xiaohan Yang Jing Liang Rong Liu Luyang Sun Yongfeng Shang | 2018 | Cell Research2018，28，9： | 5 |
| 6 | Retrofit design of composite cooling structure of a turbine blade by fluid networks and conjugate heat transfer methods显示文摘This article discusses the development of the numerical methods of gas flow coupled with heat transfer,and introduces the fluid net-works method for rapid prediction of the performance of the composite cooling structures in turbine blade.The reliability of these methods is verified by comparing experimental data.For a HPT rotor blade,a rapid prediction on the internal cooling structures is first made by using the fluid network analysis,then an assessment of aerodynamic and heat transfer characteristics is conducted.Based on the network analysis results,three ways to improve the design of the cooling structures are tested,i.e.,adjusting the cooling gas flow mass ratios for different inner cooling cavities,reducing the flow resistances of the channel turning structures,and improving the local internal cooling structure geometries with high temperature distribution.Through the verification of full three-dimensional gas/solid/coolant conjugate heat transfer calculation,we conclude that the modified design can make the overall temperature distribution more even by significantly reducing the highest temperature of the blade surface,and reasonably matching the parameters of different coolant inlets.The results show that the proposed calculation methods can remarkably reduce the design cycle of complex turbine blade cooling structure. | YAN PeiGang SHI Liang WANG XiangFeng HAN WanJin | 2013 | Science China(Technological Sciences)2013，56，12： | 5 |
| 7 | BEM/FDM Conjugate Heat Transfer Analysis of a Two-dimensional Air-cooled Turbine Blade Boundary Layer显示文摘A coupled 边界元素方法(BEM ) 和有限差别方法(频分多路复用) 被使用解决结合热转移问题一二维空气冷却汽轮机片界面层。泛泛地联合的策略被采用,在哪个地方程的每个集合被解决为其它提供边界条件。海军司烧方程被 HIT-NS 代码解决。在这代码, FDM 被收养并且被用来在液体区域解决对流的热转移。BEM 代码被用来在稳固的区域解决传导热转移。一个重申的集中标准在液体固体接口是温度和热流动的连续性。从在这篇论文采用的 BEM 的数字结果在对分析答案的结果和商业代码的结果的好同意,例如流畅 6.2。BEM 避免在另外的计算方法需要的复杂网孔并且节省计算时间。结果证明在这篇论文采用的 BEM 能与更少的边界点在数字结果给一样的精确。比较 conjugate 与一个绝热壁流动答案的数字结果结果,它在金属温度的分发揭示重要差别。结果从结合热转移分析是更精确的,他们接近汽轮机的现实主义的热环境。 | Wang Zhenfeng Yan Peigang Guo Zhaoyuan Han Wanjin | 2008 | Journal of Thermal Science2008，17，3： | 4 |
| 8 | Effects of Hot Steam Injection from the Slot at the Trailing Edge on Turbine Nozzle Vane Flow Field显示文摘Moisture removal slot configurations with three different opening widths are in turn set at the trailing edges of a turbine hollow guide vane.The flow fields are analyzed by two-phase flow numerical simulation of solving the steady three dimensional Reynolds averaged Navier-Stokes equations on the basis of the real water vapor thermo-physical properties,and the blade temperature field is solved by the fluid-solid coupling.Exergy parame- ter is introduced as a measure to evaluate the economic cost of energy conversion process.The results indicate that the bigger slot allow lower quality of hot steam in the case of the equivalent injected quantity,while it has a higher exergy effective efficiency of the mixing process in the cascade channels.The hot steam injecting at the trailing edges has an optimal injected mass flow rate for a relatively large slot,on this point the exergy effective efficiency is the maximum,namely the flow loss is the minimum. | Liang Xu Peigang Yan Hongyan Huang Wanjin Han | 2008 | Journal of Thermal Science2008，17，4： | 3 |
| 9 | Effect of volatile oil from Blumea Balsamifera(L.) DC. leaves on wound healing in mice显示文摘OBJECTIVE: To assess the effectiveness of violateoil from Blumea Balsamifera(L.) DC. leaves(BB oil)on wound healing in mice.METHODS: Undiluted BB oil and its diluted solutions with olive oil to 1/5 and 1/10 to yield BB oil1/5and BB oil1/10 were applied to the wounded skin before wound healing conditions were assessed by healing rate, histopathology, and contents of collagen, hydroxyproline, and Neuropeptide Substance P(SP). All above results were compared with the efficacies of the control, pure olive oil, basic fibroblast growth factor(BFGF), and cream of Jing Wan Hong(JWH).RESULTS: BB oil1/5and BB oil1/10 improved wound contraction and closure. Histopathology study further confirmed a desirable histological organization of wound tissues. BB oil1/5and BB oil1/10 reduced the number of inflammatory cells, increased wound-healing rates, and significantly increased the hydroxyproline content. Both BB oil1/5and BB oil1/10 improved formation of collagen, and reduced the frequency of fibroblasts. Moreover, BB oil1/5and BB oil1/10 markedly promoted SP expression. However, undiluted BB oil may induce skin thickening and hardening, inhibite collagen synthesis and delay complete skin wound healing.CONCLUSION: The BB oil1/5and BB oil1/10 promoted capillary regeneration, blood circulation, collagen deposition, granular tissue formation, epithelial deposition, and wound contraction. The mechanism underlying the action might be related to induction of SP secretion, and the proliferation and differentiation of mesenchymal cells. | Yuxin Pang Dan Wang Xuan Hu Hui Wang Wanjin Fu Zuowang Fan Xiaolu Chen Fulai Yu | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 2 |
| 10 | Unsteady Numerical Simulation of Steam-Solid Two-Phase Flow in the Governing Stage of a Steam Turbine显示文摘Solid particle erosion (SPE) in an ultra-supercritical steam turbine control stage with block configuration is investigatednumerically, based on the finite volume method and the fluid-particle coupling solver. We apply the particlediscrete phase model to model the solid particles flow, and use the Euler conservation equations to solve thecontinuous phase. The investigation is focused on the influence of the solid particle parameters (such as particlediameter, particle velocity and particle trajectory) on the erosion rate of the stator and rotor blade surface in unsteadycondition. The distributions of the highly eroded zone on the stator and rotor blade surfaces are shown anddiscussed in detail according to the mechanism of solid particle/blade wall interaction. We obtain that the erosionrate of the vane blade is sensitive to the fluctuation of the potential flow field, and the smaller particle has agreater impact on the erosion distribution of rotor blade. The erosion rate does not entirely depend on the diametersize of the solid particle. | Yufeng Li Peigang Yan Wanjin Han | 2009 | Journal of Thermal Science2009，18，4： | 2 |
| 11 | A comparision of SCE test in human lymphocytes and vicia: a hopeful technique using plants to detect mutagens and carcinogens显示文摘 | Wanjin X Zili Z | 1990 | Mutat Res1990，241，： | 1 |
| 12 | Effects of leaning and curving of blades with high turning angles on the aerodynamic characteristics of turbine rectangular cascades显示文摘 | HAN Wanjin TAN Chunqing SHI Hong | 1994 | Journal of Turbomachinery1994，116，3： | 1 |
| 13 | Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptor显示文摘 | Zhang Dawei Garuti Rita Tang Wanjin | 2008 | Proceedings of the National Academy of Sciences2008，105，13： | 1 |
| 14 | ECT2 regulates the Rho/ERK signalling axis to promote early recurrence in human hepatocellular carcinoma显示文摘 | Jianxiang Chen Hongping Xia Xiaoqian Zhang Sekar Karthik Seshachalam Veerabrahma Pratap London Lucien Ooi Wanjin Hong Kam M. Hui | 2015 | Journal of Hepatology2015，，： | 1 |
| 15 | VAMP8 is the v-SNARE that mediates basolateral exocytosis in a mouse model of alcoholic pancreatitis显示文摘 | Cosen-Binker Laura I Binker Marcelo G Wang Cheng-Chun Hong Wanjin Gaisano Herbert Y | 2008 | Journal of Clinical Investigation2008，，： | 1 |
| 16 | Numerical Study of Improving Aerodynamic Performance of Low Solidity LPT Cascade through Increasing Trailing Edge Thickness显示文摘This paper presents a new idea to reduce the solidity of low-pressure turbine(LPT) blade cascades,while remain the structural integrity of LPT blade.Aerodynamic performance of a low solidity LPT cascade was improved by increasing blade trailing edge thickness(TET).The solidity of the LPT cascade blade can be reduced by about12.5% through increasing the TET of the blade without a significant drop in energy efficiency.For the low solidity LPT cascade,increasing the TET can decrease energy loss by 23.30% and increase the flow turning angle by1.86% for Reynolds number(Re) of 25,000 and freestream turbulence intensities(FSTT) of 2.35%.The flow control mechanism governing behavior around the trailing edge of an LPT cascade is also presented.The results show that appropriate TET is important for the optimal design of high-lift load LPT blade cascades. | LI Chao YAN Peigang WANG Xiangfeng HAN Wanjin WANG Qingchao | 2016 | Journal of Thermal Science2016，25，4： | 1 |
| 17 | One-step hydrogenation-esterification of aldehyde and acid to ester over bifunction Pt catalysts:a model reaction as novel route for catalytic upgrading of fast pyrolysis bio-oil显示文摘 | Tang Yang Yu Wanjin Mo Liuye | 2008 | Energy & Fuels2008，22，5： | 1 |
| 18 | One-step hydrogenation-esterification of aldehyde and acid to ester over bifunctional Pt catalysts: A model reaction as novel route for catalytic upgrading of fast pyrolysis bio-oil显示文摘 | Tang Yang Yu Wanjin Liu Yemo | 2008 | Energy Fuels2008，22，5： | 1 |
| 19 | Some Eco-nomic Aspects of the Language Situation in China显示文摘 | Zhu Wanjin and Chen Jianmin | 1991 | Journal of Asian Pacific Communication1991，2，1： | 1 |
| 20 | Preparation of temperature sensitive molecularly imprinted polymer for solid-phase microextraction coatings on stainless steel fiber to measure ofloxacin显示文摘 | Tong Zhao Xiujuan Guan Wanjin Tang Ying Ma Haixia Zhang | 2014 | Analytica Chimica Acta2014，，： | 1 |
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