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2篇 您的检索式：作者名="Jiafu Long"

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		题名	作者	年代	出处	被引量
	1	Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway显示文摘	Youjun Li Hao Zhou Fengzhi Li Siew Wee Chan Zhijie Lin Zhiyi Wei Zhou Yang Fusheng Guo Chun Jye Lim Wancai Xing Yuequan Shen Wanjin Hong Jiafu Long Mingjie Zhang	2015	Cell Research2015，25，7：	9
	2	Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2显示文摘Protein kinase CK2 consists of two catalytic subunits (CK2α) and two regulatory subunits (CK2β). Here, we report the crystal structures of rat CK2α mutant (rCK2α-△C, 1—335) and CK2β (rCK2β). The overall topology of rCK2α-△C and rCK2β are very similar to the human enzyme, although large structural differences could be observed in the N-terminal domain of rCK2α-△C. Our reported structure of rCK2α-△C is in the close conformation state while the counterpart hCK2α is in the open conformation state, indi- cating the conformation of CK2α molecule has high plasticity. The structure of rCK2β represents the conformation of free CK2β. Upon CK2α binding, the C-terminal region undergoes a drastic conformational change. The major region of interaction within the interface of CK2α/CK2β may serve as a bridge to transmit the conformational change and thus regulate the activity of CK2α.	ZHOU WeiHong QIN XiaoHong YAN XiaoJie XIE XingQiao LI Liang FANG ShaSha LONG JiaFu ADELMAN John TANG Wei-Jen SHEN YueQuan	2009	Chinese Science Bulletin2009，54，2：	0

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