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| 1 | The Inhibitory Effect of Oridonin on the Growth of Fifteen Human Cancer Cell Lines显示文摘OBJECTIVE To study the inhibitory effect of oridonin on the growth of cancer cells. METHODS Fifteen human cancer cell lines were subjected to various concentrations of oridonin in culture medium. The inhibitory rate of cell growth was measured by the MTT assay, and compared with a negative con- trol and 5-Fu-positive control. RESULTS The 50% inhibiting concentration (IC50) and maximal inhibition (Imax) of oridonin shown by studying the growth of the cancer cell lines were as follows: leukemias (HL60 cells: 3.9 μg/ml and 73.8%, K562 cells: 4.3 μg/ml and 76.2%); esophageal cancers(SHEEC cells: 15.4 μg/ml and 99.2%, Eca109 cells: 15.1 μg/ml and 84.6%, TE1 cells: 4.0 μg/ml and 70.2%); gastric cancers (BGC823 cells: 7.6 μg/ml and 98.7%, SGC7901 cells: 12.3 μg/ml and 85.7%); colon cancers (HT29 cells: 13.6 μg/ml and 97.2%, HCT cells: 14.5 μg/ml and 96.5%); liver cancers (Bel7402 cells: 15.2 μg/ml and 89.2%, HepG2 cells: 7.1 μg/ml and 88.3%); pancreatic cancer (PC3 cells: 11.3 μg/ml and 68.4%); lung cancer (A549 cells: 18.6 μg/ml and 98.0% ); breast cancer (MCF7 cells: 18.4 μg/ml and 84.7%); uterine cervix cancer (Hela cells: 13.7 μg/ml and 98.5%). CONCLUSION Oridonin had a relatively wide anti-tumor spectrum, and a relatively strong inhibitory effect on the growth of the 15 human cancer cells. Inhibitory effects were concentration dependent. | Junhui Chen Shaobin Wang Dongyang Chen Guisheng Chang Qingfeng Xin Shoujun Yuan Zhongying Shen | 2007 | Chinese Journal of Clinical Oncology2007，4，1： | 32 |
| 2 | 三种VOCs物性对其在活性炭上吸附行为的影响显示文摘为了探讨VOC物性对活性炭吸附行为的影响,对活性炭表面物化性质进行了表征。并以甲苯、丙酮、二甲苯为吸附质,在同等实验条件下进行了固定床吸附实验。实验结果显示活性炭对3种VOCs的吸附量为二甲苯>甲苯>丙酮。将实验结果与VOC物性进行关联分析,结果表明:活性炭对有机气体的吸附量随着吸附质的分子量、分子动力学直径、沸点、密度的增大而增大,且呈现良好的正线性关系;而吸附质的极性指数和蒸气压则与活性炭吸附量呈现出相反的关系;3种活性炭对吸附质吸附能的排序均为二甲苯>甲苯>丙酮。 | 李立清 宋剑飞 孙政 WANG Shaobin 姚小龙 刘伟 刘峥 | 2011 | 化工学报2011，62，10： | 29 |
| 3 | Effects of inoculating fungi on agilawood formation in Aquilaria sinensis显示文摘Agilawood is a costly heartwood medicine obtained from Aquilaria sinensis with active ingredients mainly composed of volatile and semi-volatile substances. However, the formation time of agilawood is quite long and little is known about its formation mechanism. Two highly active fungi obtained from natural agilawood were inoculated on A. sinensis trees to understand their interaction processes and elucidate the transformation rules of induced chemical compositions within different test periods. The results demonstrated that the fungi could successfully colonize living tissues and cells and activate the host defense system, resulting in agilawood accumulation. With increasing time, the main components of A. sinensis converted into constituents or analogs of agilawood and the host exhibited 'self-injury' to prevent fungal intrusion and protect other tissues. The data presented here could provide scientific basis for producing agilawood with the two new fungi in a safe, feasible, and sustainable manner without destroying rare Aquilaria plants. | CUI JinLong GUO ShunXing FU ShaoBin XIAO PeiGen WANG MengLiang | 2013 | Chinese Science Bulletin2013，58，26： | 8 |
| 4 | Overactive bladder symptom score to evaluate efficacy of solifenacin for the treatment of overactive bladder symptoms显示文摘 | Liu Ming Wang Jianye Yang Yong An Ruihua Wen Jianguo Guan Zhichen Zheng Shaobin Wang Dongwen Song Bo Liao Limin Guo Hongqian Xiao Jiaquan Sun Yinghao Shen Zhoujun Kong Chuize He Dalin Huang Yiran Wang Xiaofeng Zhang Xu Li Hanzhong Huang Jian Zhao Xiaokun Zeng Puqing Song Xishuang Ye Zhangqun | 2014 | Chinese Medical Journal2014，，2： | 7 |
| 5 | Characterization of miRNomes in Acute and Chronic Myeloid Leukemia Cell Lines显示文摘Myeloid leukemias are highly diverse diseases and have been shown to be associated with microRNA(miRNA) expression aberrations. The present study involved an in-depth miRNome analysis of two human acute myeloid leukemia(AML) cell lines, HL-60 and THP-1, and one human chronic myeloid leukemia(CML) cell line, K562, via massively parallel signature sequencing. mRNA expression profiles of these cell lines that were established previously in our lab facilitated an integrative analysis of miRNA and mRNA expression patterns. miRNA expression profiling followed by differential expression analysis and target prediction suggested numerous miRNA signatures in AML and CML cell lines. Some miRNAs may act as either tumor suppressors or oncomiRs in AML and CML by targeting key genes in AML and CML pathways. Expression patterns of cell type-specific miRNAs could partially reflect the characteristics of K562, HL-60 and THP-1 cell lines, such as actin filament-based processes, responsiveness to stimulus and phagocytic activity. miRNAs may also regulate myeloid differentiation, since they usually suppress differentiation regulators. Our study provides a resource to further investigate the employment of miRNAs in human leukemia subtyping, leukemogenesis and myeloid development. In addition, the distinctive miRNA signatures may be potential candidates for the clinical diagnosis, prognosis and treatment of myeloid leukemias. | Qian Xiong Yadong Yang Hai Wang Jie Li Shaobin Wang Yanming Li Yaran Yang Kan Cai Xiuyan Ruan Jiangwei Yan Songnian Hu Xiangdong Fang | 2014 | Genomics, Proteomics & Bioinformatics2014，12，2： | 6 |
| 6 | Boride-based electrocatalysts:Emerging candidates for water splitting显示文摘Electrocatalytic water splitting(EWS)is a promising route to produce hydrogen in a sustainable and environment-benign manner.To realize the large-scale hydrogen production,it is paramount to develop desirable electrocatalysts with engineered structure,high catalytic activity,facile accessibility,low cost,and good durability.Of late,boride-based materials,especially transition-metal borides(TMBs),are emerging as promising candidates for the EWS process.However,so far,ittle attempt has been made to provide a comprehensive summary on these findings.Herein,this review provides the up-to-date status on upgrading the catalytic performance of TMB-based nanomaterials by regulating the internal and external characteristics.The conventional synthetic techniques are first presented for the preparation of TMB-based catalysts.Afterwards,the advanced strategies are summarized to enhance the catalytic performance of TMBs,including morphology control,component regulation,phase engineering,surface oxidation and hybridization.Then,the design principles of TMB-based electrocatalysts for high-performance EWS are outined.Lastly,the current challenges and future directions in the development of TMB-based materials are proposed.This review article is expected to envisage insights into the TMBs-based water splitting and to provide strategies for design of the next-generation TMB-based electrocatalysts. | ZhiJie Chen Xiaoguang Duan Wei Wei Shaobin Wang Zejie Zhang Bing-Jie Ni | 2020 | Nano Research2020，13，2： | 5 |
| 7 | Progress in the development of techniques based on light scattering for single nanoparticle detection显示文摘Nanoparticles have recently attracted extensive attention in view of their great potential in biomedicine and bioanalytical ap- plications. Single particle detection via light scattering offers a simple and efficient approach for the size, size distribution, and concentration analysis of nanoparticles. In particular, intrinsic heterogeneity or rare events masked by ensemble averaging can be revealed. However, the sixth power dependence of Rayleigh scattering on particle size makes it very challenging to detect individual nanoparticles of small sizes. This article is intended to provide an overview of recent progress in the development of techniques based on light scattering for the detection of single nanoparticles. | ZHU ShaoBin, WANG Shuo, YANG LingLing, HUANG TianXun & YAN XiaoMei Department of Chemical Biology, College of Chemistry and Chemical Engineering Key Laboratory for Chemical Biology of Fujian Province Key Laboratory of Analytical Science, Xiamen University, Xiamen 361005, China | 2011 | Science China Chemistry2011，54，8： | 5 |
| 8 | Changes and correlation of microorganism and flavor substances during persimmon vinegar fermentation显示文摘To investigate the microbial diversity and the change of the flavor substances during the traditional natural persimmon vinegar fermentation,two group samples from alcohol fermentation stage(A)and acetic acid fermentation stage(B)were analyzed.The results showed that Burkholderia,Lactobacillus,Acetobacter,Komagataeibacter were the main bacteria,and the major fungi were Saccharomyces,Hanseniaspora,Hortaea,and Cladosporium at the genus level.The contents of flavonoids and polyphenols in B increased by 17.91%and 26.59%compared with A,respectively.The superoxide anion scavenging activity significantly increased by 20.15%.The contents of total free amino acids were 5709.99±410.36 mg/L and 5736.16±472.02 mg/L,and the total contents of 9 organic acids were 19.89±1.20 g/L and 33.77±2.49 g/L in samples A and B,respectively.Pearson correlation analysis showed that 11 flavor compounds were related to Lactobacillus and Leuconostoc;8 and 10 compounds were respectively related to Komagataeibacter and Acetobacter;13 and 19 flavor compounds were respectively associated with Saccharomyces and Monascus.Orthogonal Partial Least Square(OPLS)model showed that the contents of Leu,Lys,and lactic acid were mainly associated with fungi,andγ-aminobutyric acid(GABA)content was correlated with Lactobacillus,Acetobacter,Leuconostoc,and Saccharomyces.This study revealed the relationship between microbial diversity and flavor compounds in persimmon vinegar produced by spontaneous fermentation.The results can provide a theoretical support for the safety and health assessment of persimmon vinegar. | Dahong Wang Mengyang Wang Luwei Cao Xiaotong Wang Jianrui Sun Jiangfeng Yuan Shaobin Gu | 2022 | Food Bioscience2022，46，2： | 4 |
| 9 | Template-free synthesis of carbon doped TiO2 mesoporous microplates for enhanced visible light photodegradation显示文摘钛二氧化物(TiO 2) 广泛地为太阳能变换和环境补习作为稳固的光催化剂被采用。与控制粒子尺寸和缩小的 bandgap 构造多孔的 TiO 2 的能力是为设计的一个必要要求高度有效并且 recyclable 光催化剂。这里,我们报导没有模板的醋酸与高 crystallinity 和 mesoporous 结构为可见光的应答的做碳的 TiO 2 microplates 的合成导致了方法。从醋酸导出的撤退电子的有二齿的羧化物 ligands 能缩小 TiO 2 的 bandgap,这被显示出(1.84 ? eV ) 实质地。而且,结果的 microplate 光催化剂展出优秀 photocatalytic 效率和稳固液体的分离性能,它将为未来是有益的工业应用。 | Juming Liu Lu Han Huiyan Ma Hao Tian Jucai Yang Qiancheng Zhang Benjamin J. Seligmann Shaobin Wang Jian Liu | 2016 | Science Bulletin2016，61，19： | 4 |
| 10 | A Superaerophobic Bimetallic Selenides Heterostructure for Efficient Industrial-Level Oxygen Evolution at Ultra-High Current Densities显示文摘Cost-effective and stable electrocatalysts with ultra-high current densities for electrochemical oxygen evolution reaction(OER)are critical to the energy crisis and environmental pollution.Herein,we report a superaerophobic three dimensional(3D)heterostructured nanowrinkles of bimetallic selenides consisting of crystalline NiSe2 and NiFe2Se4 grown on NiFe alloy(NiSe2/NiFe2Se4@NiFe)prepared by a thermal selenization procedure.In this unique 3D heterostructure,numerous nanowrinkles of NiSe2/NiFe2Se4 hybrid with a thickness of ~100 nm are grown on NiFe alloy in a uniform manner.Profiting by the large active surface area and high electronic conductivity,the superaerophobic NiSe2/NiFe2Se4@NiFe heterostructure exhibits excellent electrocatalytic activity and durability towards OER in alkaline media,outputting the low potentials of 1.53 and 1.54 V to achieve ultra-high current densities of 500 and 1000 mA cm^−2,respectively,which is among the most active Ni/Fe-based selenides,and even superior to the benchmark Ir/C catalyst.The in-situ derived FeOOH and NiOOH species from NiSe2/NiFe2Se4@NiFe are deemed to be efficient active sites for OER. | Jiaxin Yuan Xiaodi Cheng Hanqing Wang Chaojun Lei Sameer Pardiwala Bin Yang Zhongjian Li Qinghua Zhang Lecheng Lei Shaobin Wang Yang Hou | 2020 | Nano-Micro Letters2020，12，8： | 4 |
| 11 | Geochronological and geochemical constraints on the petrogenesis of late Mesoproterozoic mafic and granitic rocks in the southwestern Yangtze Block显示文摘Late Mesoproterozoic igneous rocks in the SW Yangtze Block are important for understanding the role of it in reconstruction of the Rodinia supercontinent.In the present study,we report new geochronological,geochemical,and Nd-Hf isotopic data for the Cuoke plagioclase amphibolites and granites in the SW Yangtze Block.Geochronological results show that the plagioclase amphibolites and granites have similar late Mesoproterozoic zircon U-Pb ages of 1168-1162 Ma,constituting a bimodal igneous assemblage.The plagioclase amphibolites have high and variable TiO2 contents(1.15-4.30 wt.%)and Mg#(34-66)values,similar to the tholeiitic series.They are characterized by enrichment in LREEs and LILEs,and have OIB-like affinities with positive Nb and Ta anomalies.The plagioclase amphibolites have positive whole-rockεNd(t)(+3.2 to+4.3)and zirconεHf(t)(+4.3 to+10.7)values,indicating that they were derived from an OIB-like asthenospheric mantle source.The granites belong to the reduced peralkaline A-type series and have negativeεNd(t)value of-6.0 andεHf(t)values of-5.8 to-13.8,indicating a derivation from the partial melting of ancient mafic lower crust.In combination with the~1.05-1.02 Ga bimodal igneous assemblage in the SW Yangtze Block,we propose that the Cuoke 1168-1162 Ma igneous rocks were likely formed in a continental rift basin and argue against the existance of Grenvillian Orogen in the SW Yangtze Block during the late Mesoproterozoic. | Guichun Liu Jing Li Xin Qian Qinglai Feng Wei Wang Guangyan Chen Shaobin Hu | 2021 | Geoscience Frontiers2021，12，1： | 3 |
| 12 | Location and size regulation of manganese oxides within mesoporous silica for enhanced antibiotic degradation显示文摘Refractory antibiotics in domestic wastewater are hard to be completely eliminated by conventional methods,and then lead to severe environmental contamination and adverse effects on public health.In present work,advanced oxidation processes(AOPs)are adopted to remove the antibiotic of sul-fachloropyridazine(SCP).Nanosized Mn_(2)O_(3) was fabricated on the SBA-15 material to catalytically acti-vate potassium peroxydisulfate(PDS)to generate reactive oxygen radicals of.OH and SO_(4).for SCP degradation.The effects of location and size of Mn_(2)O_(3) were explored through choosing either the as-made or template free SBA-15 as the precursor of substrate.Great influences from the site and size of Mn_(2)O_(3) on the oxidation activity were discovered.It was found that Mn_(2)O_(3) with a large size at the exterior of SBA-15(Mn-tfSBA)was slightly easier to degrade SCP at a low manganese loading of 1.0-2.0 mmol.g;however,complete SCP removal could only be achieved on the catalyst of Mn_(2)O_(3) with a refined size at the interior of SBA-15(Mn-asSBA).Moreover,the SO_(4).species were revealed to be the decisive radicals in the SCP degradation processes.Exploring the as-made mesoporous silica as a support provides a new idea for the further development of environmentally friendly catalysts. | Min Lu Mengxuan Liu Chunli Xu Yu Yin Lei Shi Hong Wu Aihua Yuan Xiao-Ming Ren Shaobin Wang Hongqi Sun | 2022 | Chinese Journal of Chemical Engineering2022，35，8： | 3 |
| 13 | Autophagy of cancer stem cells is involved with chemoresistance of colon cancer cells显示文摘 | Shaobin Wu Xianwei Wang Jinxiang Chen Yuxiang Chen | 2013 | Biochemical and Biophysical Research Communications2013，，4： | 2 |
| 14 | Li intercalation in an MoSe_(2) electrocatalyst:In situ observation and modulation of its precisely controllable phase engineering for a high-performance flexible Li-S battery显示文摘Sophisticated efficient electrocatalysts are essential to rectifying the shuttle effect and realizing the high performance of flexible lithium-sulfur batteries(LSBs).Phase transformation of MoSe_(2) from the 2H phase to the 1T phase has been proven to be a significant method to improve the catalytic activity.However,precisely controllable phase engineering of MoSe_(2) has rarely been reported.Herein,by in situ Li ions intercalation in MoSe_(2),a precisely controllable phase evolution from 2H-MoSe_(2) to 1T-MoSe_(2) was realized.More importantly,the definite functional relationship between cut-off voltage and phase structure was first identified for phase engineering through in situ observation and modulation methods.The sulfur host(CNFs/1T-MoSe_(2))presents high charge density,strong polysulfides adsorption,and catalytic kinetics.Moreover,Li-S cells based on it display capacity retention of 875.3mAh g^(-1) after 500 cycles at 1 C and an areal capacity of 8.71mAh cm^(-2) even at a high sulfur loading of 8.47mg cm^(-2).Furthermore,the flexible pouch cell exhibiting decent performance will endow a promising potential in the wearable energy storage field.This study proposes an effective strategy to precisely control the phase structure of MoSe_(2),which may provide the reference to fabricate the highly efficient electrocatalysts for LSBs and other energy systems. | Yunke Wang Yige Zhao Kangli Liu Shaobin Wang Neng Li Guosheng Shao Feng Wang Peng Zhang | 2023 | Carbon Energy2023，5，2： | 2 |
| 15 | A Comparative study of Fenton and Fenton-like reaction kinetics in decolourisation of wastewater显示文摘 | Shaobin Wang | 2007 | Dyes and Pigments2007，，3： | 2 |
| 16 | Carbon-based single atom catalyst: Synthesis, characterization, DFT calculations显示文摘Carbon-based single-atom catalysts(SACs) with atomic sizes of active sites have become the promising candidates for a variety of catalytic systems because of their high atom utilization, and unique electronic structures. Different types of single-atom sites can be fabricated via multiple preparation strategies, which would demonstrate distinct different coordination configurations and electronic features, and ultimately affected the structure-catalysis relationship of SACs in targeted reactions. As a result, it is necessary to identify the active sites of SACs and understand the structure-catalysis relationship of SACs at the atomic scale. In this review, a variety of preparation strategies of carbon-based SACs were documented. Then, the recent development on versatile characterization techniques and computational achievements were summarized regarding in understanding the electronic and geometric characteristics of carbon-based SACs.Finally, major challenges and development directions concerning single-atom sites identification and advanced tools development are discussed to shed light on future research of carbon-based SACs. | Yanan Shang Xiaoguang Duan Shaobin Wang Qinyan Yue Baoyu Gao Xing Xu | 2022 | Chinese Chemical Letters2022，33，2： | 2 |
| 17 | Synthesis of Co oxide doped carbon aerogel catalyst and catalytic performance in heterogeneous oxidation of phenol in water显示文摘 | Yasnessya Hardjono Hongqi Sun Huyong Tian C.E. Buckley Shaobin Wang | 2011 | Chemical Engineering Journal2011，，1： | 2 |
| 18 | Effects of Silicon Fertilizer on Rice Blast (Magnaporthe oryzae) Green Control, Rice Growth and Yield显示文摘Three doses of silicon fertilizer and seven dominant rice varieties were selected to study the effects of silicon fertilizer on rice blast(Magnaporthe oryzae)green control,rice growth and yield.The results showed application of silicon fertilizer had certain control effect on panicle blast,and was beneficial for rice growth and yield.However,application effect varied among different varieties,and application of silicon fertilizer at the dose of 225 kg/hm2 received the best effect.Applying silicon fertilizer to control rice blast is safe and environmental-friendly,which is beneficial to the production of green food production. | Lai Tiankui Deng Yuxian Ge Shaobin Wang Xiumei Li Chuanying Yang Jianyuan | 2020 | Plant Diseases and Pests2020，11，3： | 2 |
| 19 | Genomic evidence of lung carcinogenesis associated with coal smoke in Xuanwei area, China显示文摘Xuanwei area, in southwestern China,harbors the highest female lung cancer rate in the country(Supplementary Table 1) [1]. Epidemiological studies have shown that lung cancer incidence in Xuanwei area is associated with the use of different types of local coal for household cooking and heating [2]. The genomic landscape of Xuanwei female adenocarcinoma(XWFA), the most distinctive feature of lung cancer in Xuanwei, has yet to be elucidated systematically. Here,we provide the fundamental resource of genomic datasets for further exploration of XWFA molecular mechanisms and development of targetable therapy. | Honglei Zhang Chao Liu Li Li Xu Feng Qing Wang Jihua Li Shaobin Xu Shuting Wang Qianlu Yang Zhenghai Shen Jinhua Su Xiaosan Su Ruifen Sun Xuhong Zhou Junliang Wang Yongchun Zhou Baowei Jiao Wanbao Ding Xianbao Cao Yue Wang Yunchao Huang Lianhua Ye | 2021 | National Science Review2021，8，12： | 2 |
| 20 | Overexpression of EphA2 correlates with epithelial–mesenchymal transition-related proteins in gastric cancer and their prognostic importance for postoperative patients显示文摘 | Futao Hou Weijie Yuan Jin Huang Liyuan Qian Zhikang Chen Jie Ge Shaobin Wu Jinxiang Chen Jixu Wang Zihua Chen | 2012 | Medical Oncology2012，，4： | 2 |
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