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| 1 | The Inhibitory Effect of Oridonin on the Growth of Fifteen Human Cancer Cell Lines显示文摘OBJECTIVE To study the inhibitory effect of oridonin on the growth of cancer cells. METHODS Fifteen human cancer cell lines were subjected to various concentrations of oridonin in culture medium. The inhibitory rate of cell growth was measured by the MTT assay, and compared with a negative con- trol and 5-Fu-positive control. RESULTS The 50% inhibiting concentration (IC50) and maximal inhibition (Imax) of oridonin shown by studying the growth of the cancer cell lines were as follows: leukemias (HL60 cells: 3.9 μg/ml and 73.8%, K562 cells: 4.3 μg/ml and 76.2%); esophageal cancers(SHEEC cells: 15.4 μg/ml and 99.2%, Eca109 cells: 15.1 μg/ml and 84.6%, TE1 cells: 4.0 μg/ml and 70.2%); gastric cancers (BGC823 cells: 7.6 μg/ml and 98.7%, SGC7901 cells: 12.3 μg/ml and 85.7%); colon cancers (HT29 cells: 13.6 μg/ml and 97.2%, HCT cells: 14.5 μg/ml and 96.5%); liver cancers (Bel7402 cells: 15.2 μg/ml and 89.2%, HepG2 cells: 7.1 μg/ml and 88.3%); pancreatic cancer (PC3 cells: 11.3 μg/ml and 68.4%); lung cancer (A549 cells: 18.6 μg/ml and 98.0% ); breast cancer (MCF7 cells: 18.4 μg/ml and 84.7%); uterine cervix cancer (Hela cells: 13.7 μg/ml and 98.5%). CONCLUSION Oridonin had a relatively wide anti-tumor spectrum, and a relatively strong inhibitory effect on the growth of the 15 human cancer cells. Inhibitory effects were concentration dependent. | Junhui Chen Shaobin Wang Dongyang Chen Guisheng Chang Qingfeng Xin Shoujun Yuan Zhongying Shen | 2007 | Chinese Journal of Clinical Oncology2007，4，1： | 32 |
| 2 | 三种VOCs物性对其在活性炭上吸附行为的影响显示文摘为了探讨VOC物性对活性炭吸附行为的影响,对活性炭表面物化性质进行了表征。并以甲苯、丙酮、二甲苯为吸附质,在同等实验条件下进行了固定床吸附实验。实验结果显示活性炭对3种VOCs的吸附量为二甲苯>甲苯>丙酮。将实验结果与VOC物性进行关联分析,结果表明:活性炭对有机气体的吸附量随着吸附质的分子量、分子动力学直径、沸点、密度的增大而增大,且呈现良好的正线性关系;而吸附质的极性指数和蒸气压则与活性炭吸附量呈现出相反的关系;3种活性炭对吸附质吸附能的排序均为二甲苯>甲苯>丙酮。 | 李立清 宋剑飞 孙政 WANG Shaobin 姚小龙 刘伟 刘峥 | 2011 | 化工学报2011，62，10： | 29 |
| 3 | Livelihood diversification of farmers and nomads of eastern transect in Tibetan Plateau显示文摘在西藏的高原的农民和流浪者的生计被草地和草药的资源退化严重地影响。怎么帮助他们完成生计多样化是一个关键持续发展问题。这份报纸在西藏的高原在东方横断的 3 个区域检验生计财产,生计多样化水平和农民和流浪者的生计策略。结果证明生计多样化是流行策略。从高山塞满区域到山高原区域和高原区域,生计多样化水平被减少,并且扩大生计的生计活动和比例也减少。有举起的增加的生计财产和生计多样化水平减少,主要出现在人的财产和自然财产。生计多样化水平是高度有生计财产的关联词,主要出现在自然财产,人的财产和社会财产。仍然基于存在生计财产,农民和流浪者的生计改进策略主要正在提起家畜和挖的植物,并且更少的农民和流浪者认为离开农场是雇用或做的生意。在高原区域的流浪者应该在高山峡区域和山高原区域从人的扩大生计的经验学习大部分。因此,政府的帮助应该集中于减轻生计多样化的限制因素并且帮助他们改进他们的能力建立扩大类型生计。 | YAN Jianzhong WU Yingying ZHANG Yili ZHOU Shaobin | 2010 | Journal of Geographical Sciences2010，20，5： | 22 |
| 4 | α-Asarone suppresses the proliferation and migration of ASMCs through targeting the IncRNA-PVT1/miR-203a/E2F3 signal pathway in RSV-infected rats显示文摘气喘是长期的煽动性的肺的疾病,呼吸 syncytial 病毒(RSV ) 感染是在婴儿和小孩子的更低的呼吸的道病的一个普通原因。-Asarone 介绍许多药理学效果并且被表明了在对待气喘有用。然而,在感染 RSV 的气喘的 -asarone 的功能的机制没被调查。长非编码的 RNA (lncRNAs ) 被报导了在许多生物过程起关键作用。尽管许多 lncRNAs 被描绘了,很少在气喘被报导,特别在导致 RSV 的气喘。当前,一条新奇 post-transcriptional 规定在哪个 lncRNAs 作为竞争内长的 RNA (ceRNAs ) 工作竞争地擦掉 miRNAs 被建议了,从而调整目标基因。在现在的学习,我们建立了一个感染 RSV 的 Sprague-Dawley 老鼠模型并且证明 lncRNA-PVT1 在对待导致 RSV 的气喘,和 lncRNA-PVT1 涉及 -asarone 的机制由作为竞争地擦掉 miR-203a 的 ceRNA 工作调整 E2F3 的表示。 | Xiao Yu Zhe Zhe Binqing Tang Shaobin Li Ling Tang Yingen Wu Xiaorong Chen Hong Fang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，7： | 14 |
| 5 | Shaking table experimental study of recycled concrete frame-shear wall structures显示文摘In this study, four 1/5 scaled shaking table tests were conducted to investigate the seismic performance of recycled concrete frame-shear wall structures with different recycled aggregates replacement rates and concealed bracing detail. The four tested structures included one normal concrete model, one recycled coarse aggregate concrete model, and two recycled coarse and fi ne aggregate concrete models with or without concealed bracings inside the shear walls. The dynamic characteristics, dynamic response and failure mode of each model were compared and analyzed. Finite element models were also developed and nonlinear time-history response analysis was conducted. The test and analysis results show that the seismic performance of the recycled coarse aggregate concrete frame-shear wall structure is slightly worse than the normal concrete structure. The seismic resistance capacity of the recycled concrete frame-shear wall structure can be greatly improved by setting up concealed bracings inside the walls. With appropriate design, the recycled coarse aggregate concrete frame-shear wall structure and recycled concrete structure with concealed bracings inside the walls can be applied in buildings. | Zhang Jianwei Cao Wanlin Meng Shaobin Yu Cheng Dong Hongying | 2014 | Earthquake Engineering and Engineering Vibration2014，13，2： | 8 |
| 6 | Effects of inoculating fungi on agilawood formation in Aquilaria sinensis显示文摘Agilawood is a costly heartwood medicine obtained from Aquilaria sinensis with active ingredients mainly composed of volatile and semi-volatile substances. However, the formation time of agilawood is quite long and little is known about its formation mechanism. Two highly active fungi obtained from natural agilawood were inoculated on A. sinensis trees to understand their interaction processes and elucidate the transformation rules of induced chemical compositions within different test periods. The results demonstrated that the fungi could successfully colonize living tissues and cells and activate the host defense system, resulting in agilawood accumulation. With increasing time, the main components of A. sinensis converted into constituents or analogs of agilawood and the host exhibited 'self-injury' to prevent fungal intrusion and protect other tissues. The data presented here could provide scientific basis for producing agilawood with the two new fungi in a safe, feasible, and sustainable manner without destroying rare Aquilaria plants. | CUI JinLong GUO ShunXing FU ShaoBin XIAO PeiGen WANG MengLiang | 2013 | Chinese Science Bulletin2013，58，26： | 8 |
| 7 | Overactive bladder symptom score to evaluate efficacy of solifenacin for the treatment of overactive bladder symptoms显示文摘 | Liu Ming Wang Jianye Yang Yong An Ruihua Wen Jianguo Guan Zhichen Zheng Shaobin Wang Dongwen Song Bo Liao Limin Guo Hongqian Xiao Jiaquan Sun Yinghao Shen Zhoujun Kong Chuize He Dalin Huang Yiran Wang Xiaofeng Zhang Xu Li Hanzhong Huang Jian Zhao Xiaokun Zeng Puqing Song Xishuang Ye Zhangqun | 2014 | Chinese Medical Journal2014，，2： | 7 |
| 8 | Characterization of miRNomes in Acute and Chronic Myeloid Leukemia Cell Lines显示文摘Myeloid leukemias are highly diverse diseases and have been shown to be associated with microRNA(miRNA) expression aberrations. The present study involved an in-depth miRNome analysis of two human acute myeloid leukemia(AML) cell lines, HL-60 and THP-1, and one human chronic myeloid leukemia(CML) cell line, K562, via massively parallel signature sequencing. mRNA expression profiles of these cell lines that were established previously in our lab facilitated an integrative analysis of miRNA and mRNA expression patterns. miRNA expression profiling followed by differential expression analysis and target prediction suggested numerous miRNA signatures in AML and CML cell lines. Some miRNAs may act as either tumor suppressors or oncomiRs in AML and CML by targeting key genes in AML and CML pathways. Expression patterns of cell type-specific miRNAs could partially reflect the characteristics of K562, HL-60 and THP-1 cell lines, such as actin filament-based processes, responsiveness to stimulus and phagocytic activity. miRNAs may also regulate myeloid differentiation, since they usually suppress differentiation regulators. Our study provides a resource to further investigate the employment of miRNAs in human leukemia subtyping, leukemogenesis and myeloid development. In addition, the distinctive miRNA signatures may be potential candidates for the clinical diagnosis, prognosis and treatment of myeloid leukemias. | Qian Xiong Yadong Yang Hai Wang Jie Li Shaobin Wang Yanming Li Yaran Yang Kan Cai Xiuyan Ruan Jiangwei Yan Songnian Hu Xiangdong Fang | 2014 | Genomics, Proteomics & Bioinformatics2014，12，2： | 6 |
| 9 | Performances of improved Tent chaos-based FM radar signal显示文摘A novel algorithm is proposed to solve the poor performance problem of the Tent chaos-based frequency modulation(FM) signal for range-Doppler imaging,which takes it into complex multi-segment system by increasing its segments.The simulation results show that the effectiveness of the proposed algorithm,as well as the performance of the improved Tent FM signal is obvious in a multipath or noise propagation environment. | Shaobin Xie Zishu He Jinfeng Hu Lidong Liu Jichun Pan | 2012 | Journal of Systems Engineering and Electronics2012，23，3： | 6 |
| 10 | Full-Sized Pore Structure and Fractal Characteristics of Marine-Continental Transitional Shale: A Case Study in Qinshui Basin, North China显示文摘Based on 10 shale samples collected from 4 wells in Qinshui Basin,we investigate the full-sized pore structure and fractal characteristics of Marine-Continental transitional shale by performing organic geochemistry,mineralogical composition,Nitrogen gas adsorption(N2 adsorption)and Nuclear Magnetic Resonance(NMR)measurements and fractal analysis.Results show that the TOC content of the shale samples is relatively high,with an average value of 2.44wt%,and the thermal evolution is during the mature-over mature stage.The NMR T2 spectrum can be used to characterize the fullsized pore structure characteristics of shale.By combining N2 adsorption pore structure parameters and NMR T2 spectrums,the surface relaxivity of samples are calculated to be between 1.7877 um/s and 5.2272 um/s.On this basis,the T2 spectrums are converted to full-sized pore volume and surface area distribution curves.The statistics show that the pore volume is mainly provided by mesopore,followed by micropore,and the average percentages are 65.04%and 30.83%respectively;the surface area is mainly provided by micropore,followed by mesopore,and the average percentages are 60.8004%and 39.137%respectively;macropore contributes little to pore volume and surface area.The pore structure characteristics of shale have no relationship with TOC,but strong relationships with clay minerals content.NMR fractal dimensions Dmicro and Dmeso have strong positive relationships with the N2 adsorption fractal dimensions D1 and D2 respectively,indicating that Dmicro can be used to characterize the fractal characteristics of pore surface,and Dmeso can be used to characterize the fractal characteristics of pore structure.The shale surface relaxivity is controlled by multiple factors.The increasing of clay mineral content,pore surface area,pore surface fractal dimension and the decreasing of average pore size,will all lead to the decreasing of shale surface relaxivity. | YIN Liangliang GUO Shaobin | 2019 | Acta Geologica Sinica(English Edition)2019，93，3： | 5 |
| 11 | Wentzel-Kramer-Brillouin and finite-difierence time-domain analysis of Terahertz band electromagnetic characteristics of target coated with unmagnetized plasma显示文摘We investigate computationally the attenuation and reffection of Terahertz (THz) wave using targets coated with plasmas. The simulators are the Wentzel-Kramer-Brillouin (WKB) method and finite-difierence time-domain (FDTD) method. The relation between the frequency of the incident electromagnetic (EM) wave and the attenuation caused by unmagnitized plasma is analyzed. The results demonstrate that the amount of absorbed power is a decreasing function of the EM wave frequency and the plasma collision frequency. For THz band incident wave, the attenuation that is caused by plasma is small when the plasma has common density and the collision frequency. This conclusion has fine applying foreground for plasma anti stealth. | Liu Shaobin Zhou Tao Liu Meilin Hong Wei | 2008 | Journal of Systems Engineering and Electronics2008，19，1： | 5 |
| 12 | Boride-based electrocatalysts:Emerging candidates for water splitting显示文摘Electrocatalytic water splitting(EWS)is a promising route to produce hydrogen in a sustainable and environment-benign manner.To realize the large-scale hydrogen production,it is paramount to develop desirable electrocatalysts with engineered structure,high catalytic activity,facile accessibility,low cost,and good durability.Of late,boride-based materials,especially transition-metal borides(TMBs),are emerging as promising candidates for the EWS process.However,so far,ittle attempt has been made to provide a comprehensive summary on these findings.Herein,this review provides the up-to-date status on upgrading the catalytic performance of TMB-based nanomaterials by regulating the internal and external characteristics.The conventional synthetic techniques are first presented for the preparation of TMB-based catalysts.Afterwards,the advanced strategies are summarized to enhance the catalytic performance of TMBs,including morphology control,component regulation,phase engineering,surface oxidation and hybridization.Then,the design principles of TMB-based electrocatalysts for high-performance EWS are outined.Lastly,the current challenges and future directions in the development of TMB-based materials are proposed.This review article is expected to envisage insights into the TMBs-based water splitting and to provide strategies for design of the next-generation TMB-based electrocatalysts. | ZhiJie Chen Xiaoguang Duan Wei Wei Shaobin Wang Zejie Zhang Bing-Jie Ni | 2020 | Nano Research2020，13，2： | 5 |
| 13 | Progress in the development of techniques based on light scattering for single nanoparticle detection显示文摘Nanoparticles have recently attracted extensive attention in view of their great potential in biomedicine and bioanalytical ap- plications. Single particle detection via light scattering offers a simple and efficient approach for the size, size distribution, and concentration analysis of nanoparticles. In particular, intrinsic heterogeneity or rare events masked by ensemble averaging can be revealed. However, the sixth power dependence of Rayleigh scattering on particle size makes it very challenging to detect individual nanoparticles of small sizes. This article is intended to provide an overview of recent progress in the development of techniques based on light scattering for the detection of single nanoparticles. | ZHU ShaoBin, WANG Shuo, YANG LingLing, HUANG TianXun & YAN XiaoMei Department of Chemical Biology, College of Chemistry and Chemical Engineering Key Laboratory for Chemical Biology of Fujian Province Key Laboratory of Analytical Science, Xiamen University, Xiamen 361005, China | 2011 | Science China Chemistry2011，54，8： | 5 |
| 14 | Changes and correlation of microorganism and flavor substances during persimmon vinegar fermentation显示文摘To investigate the microbial diversity and the change of the flavor substances during the traditional natural persimmon vinegar fermentation,two group samples from alcohol fermentation stage(A)and acetic acid fermentation stage(B)were analyzed.The results showed that Burkholderia,Lactobacillus,Acetobacter,Komagataeibacter were the main bacteria,and the major fungi were Saccharomyces,Hanseniaspora,Hortaea,and Cladosporium at the genus level.The contents of flavonoids and polyphenols in B increased by 17.91%and 26.59%compared with A,respectively.The superoxide anion scavenging activity significantly increased by 20.15%.The contents of total free amino acids were 5709.99±410.36 mg/L and 5736.16±472.02 mg/L,and the total contents of 9 organic acids were 19.89±1.20 g/L and 33.77±2.49 g/L in samples A and B,respectively.Pearson correlation analysis showed that 11 flavor compounds were related to Lactobacillus and Leuconostoc;8 and 10 compounds were respectively related to Komagataeibacter and Acetobacter;13 and 19 flavor compounds were respectively associated with Saccharomyces and Monascus.Orthogonal Partial Least Square(OPLS)model showed that the contents of Leu,Lys,and lactic acid were mainly associated with fungi,andγ-aminobutyric acid(GABA)content was correlated with Lactobacillus,Acetobacter,Leuconostoc,and Saccharomyces.This study revealed the relationship between microbial diversity and flavor compounds in persimmon vinegar produced by spontaneous fermentation.The results can provide a theoretical support for the safety and health assessment of persimmon vinegar. | Dahong Wang Mengyang Wang Luwei Cao Xiaotong Wang Jianrui Sun Jiangfeng Yuan Shaobin Gu | 2022 | Food Bioscience2022，46，2： | 4 |
| 15 | Rockburst characteristics of several hard brittle rocks:A true triaxial experimental study显示文摘Rockburst is a typical rock failure which frequently threatens both human life and construction equipment during highly stressed underground excavation.Rock lithology is a control factor of rockburst.In this paper,rockburst tests were conducted on rectangular prismatic specimens of six types of intact hard brittle rocks,i.e.granodiorite,granite,marble,basalt,sandstone and limestone,under one-free-face true triaxial loading conditions.With the use of high-speed cameras,an acoustic emission(AE)system and a scanning electron microscope(SEM),rockburst of different rocks was investigated.The results show that the strainbursts of granodiorite,granite and marble were accompanied by tensile splitting near the free face,and consequently were relatively strong with a large amount of fragment ejection and kinetic energy release.For basalt,sandstone and limestone,failure was primarily dominated by shear rupture.The strainbursts of basalt and sandstone were relatively small with minor fragment ejection and kinetic energy release;while no burst failure occurred on limestone due to its relatively low peak strength.Rock strength,fracturing and fragmentation characteristics,and failure modes of different rocks can significantly affect rockburst proneness and magnitude.The AE evolution coupled with SEM analysis reveals that the differences in the inhe rent microstructures and fracture evolution under loading are the primary factors accounting for different rockbursts in various rock types. | Shaobin Zhai Guoshao Su Shunde Yin Bin Zhao Liubin Yan | 2020 | Journal of Rock Mechanics and Geotechnical Engineering2020，12，2： | 4 |
| 16 | Piecewise linear recursive convolution FDTD method for magnetized plasmas显示文摘The piecewise linear recursive convolution (PL RC) finite-different time-domain (FDTD) method greatly improves accuracy over the original recursive convolution (RC) FDTD approach but retains its speed and efficiency advantages. A PLRC-FDTD formulation for magnetized plasma which incorporates both anisotropy and frequency dispersion at the same time is presented, enabled the transient analysis of magnetized plasma media. The technique is illustrated by numerical simulations the reflection and transmission coefficients through a magnetized plasma layer. The results show that the PLRC-FDTD method has significantly improved the accuracy over the original RC method. | Liu Song Zhong Shuangying Liu Shaobin | 2006 | Journal of Systems Engineering and Electronics2006，17，2： | 4 |
| 17 | Neofusicoccum parvum causing canker of seedlings of Juglans regia in China显示文摘Cankered, dying seedlings of Juglans regia were observed in Shaanxi province in the northwest region of China. Neofusicoccum parvum was isolated from these cankered tissues, with the identification based on morphology and an ITS-nr DNA sequence. In order to demonstrate how cultures of N. parvum could cause the expected symptoms, artificial infection, using these isolates and re-isolation of the pathogen, was used. This is the first report on this taxon as a walnut canker pathogen in China. | Zhongdong Yu Guanghui Tang Shaobin Peng Hui Chen Meizhi Zhai | 2015 | Journal of Forestry Research2015，26，4： | 4 |
| 18 | Template-free synthesis of carbon doped TiO2 mesoporous microplates for enhanced visible light photodegradation显示文摘钛二氧化物(TiO 2) 广泛地为太阳能变换和环境补习作为稳固的光催化剂被采用。与控制粒子尺寸和缩小的 bandgap 构造多孔的 TiO 2 的能力是为设计的一个必要要求高度有效并且 recyclable 光催化剂。这里,我们报导没有模板的醋酸与高 crystallinity 和 mesoporous 结构为可见光的应答的做碳的 TiO 2 microplates 的合成导致了方法。从醋酸导出的撤退电子的有二齿的羧化物 ligands 能缩小 TiO 2 的 bandgap,这被显示出(1.84 ? eV ) 实质地。而且,结果的 microplate 光催化剂展出优秀 photocatalytic 效率和稳固液体的分离性能,它将为未来是有益的工业应用。 | Juming Liu Lu Han Huiyan Ma Hao Tian Jucai Yang Qiancheng Zhang Benjamin J. Seligmann Shaobin Wang Jian Liu | 2016 | Science Bulletin2016，61，19： | 4 |
| 19 | In situ synthesis of graphene oxide/gold nanorods theranostic hybrids for efficient tumor computed tomography imaging and photothermal therapy显示文摘Graphene 氧化物 / 黄金 nanorod (GO/GNR ) nanohybrids 被混合聚苯乙烯 sulfonate (PSS ) 在房间温度在 situ 生长方法与 GO-seed-mediated 和 gold-seed-mediated 综合 functionalized 去,第二等的生长答案,和金种子。与 GO/GNRs 或 graphene (G)/GNRs 的前 situ 准备方法相比,在里面 GO/GNRs 的 situ 合成在他们的附件前处理了 GNR 的聚集的问题到 GO 上。方法直接、环境友好。GO/GNRs 在 vitro 显示出显著 photothermal 效果。GO/GNR nanohybrids 的温度在女人上从 25 ~ 49.9 增加了光谱为宽事件角度的范围(365 ~ 1,100 nm )(0io 是超过 6.00 ~ 10 个病人和 35 age-/gender-matched 控制(吝啬的 s 吗?? | Bingmei Sun Jinrui Wu Shaobin Cui Huanhuan Zhu Wei An Qingge Fu Chengwei Shao Aihua Yao Bingdi Chen Donglu Shi | 2017 | Nano Research2017，10，1： | 4 |
| 20 | A Superaerophobic Bimetallic Selenides Heterostructure for Efficient Industrial-Level Oxygen Evolution at Ultra-High Current Densities显示文摘Cost-effective and stable electrocatalysts with ultra-high current densities for electrochemical oxygen evolution reaction(OER)are critical to the energy crisis and environmental pollution.Herein,we report a superaerophobic three dimensional(3D)heterostructured nanowrinkles of bimetallic selenides consisting of crystalline NiSe2 and NiFe2Se4 grown on NiFe alloy(NiSe2/NiFe2Se4@NiFe)prepared by a thermal selenization procedure.In this unique 3D heterostructure,numerous nanowrinkles of NiSe2/NiFe2Se4 hybrid with a thickness of ~100 nm are grown on NiFe alloy in a uniform manner.Profiting by the large active surface area and high electronic conductivity,the superaerophobic NiSe2/NiFe2Se4@NiFe heterostructure exhibits excellent electrocatalytic activity and durability towards OER in alkaline media,outputting the low potentials of 1.53 and 1.54 V to achieve ultra-high current densities of 500 and 1000 mA cm^−2,respectively,which is among the most active Ni/Fe-based selenides,and even superior to the benchmark Ir/C catalyst.The in-situ derived FeOOH and NiOOH species from NiSe2/NiFe2Se4@NiFe are deemed to be efficient active sites for OER. | Jiaxin Yuan Xiaodi Cheng Hanqing Wang Chaojun Lei Sameer Pardiwala Bin Yang Zhongjian Li Qinghua Zhang Lecheng Lei Shaobin Wang Yang Hou | 2020 | Nano-Micro Letters2020，12，8： | 4 |
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