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| 1 | Molecular Mechanisms Regulating Rapid Stress Signaling Networks in Arabidopsis显示文摘As sessile organisms plants must cope with ever changing environmental conditions.To survive plants have evolved elaborate mechanisms to perceive and rapidly respond to a diverse range of abiotic and biotic stresses.Central to this response is the ability to modulate gene expression at both the transcriptional and posttranscriptional levels.This review will focus on recent progress that has been made towards understanding the rapid reprogramming of the transcriptome that occurs in response to stress as well as emerging mechanisms underpinning the reprogramming of gene expression in response to stress. | Justin W. Walley Katayoon Dehesh | 2010 | Journal of Integrative Plant Biology2010,52,4: | 11 |
| 2 | Assessing the impact of TB/HIV services integration on TB treatment outcomes and their relevance in TB/HIV monitoring in Ghana显示文摘Background:The impact of the human immunodeficiency virus(HIV)on tuberculosis(TB),and the implications for TB and HIV control,is a public health challenge in Ghana-almost a quarter(23%)of all TB cases were HIV positive in 2010.The integration of TB/HIV services has therefore emerged as an essential component of the national response to TB and HIV.The aim is to reduce fragmentation,improve access,enhance efficiency and improve quality of care.Ghana’s TB/HIV policy comprises three linked sets of activities:effective implementation of the Stop TB Strategy for TB control,improved HIV prevention and care,and the implementation of additional TB/HIV activities.Different models of service delivery with increasing integration of TB/HIV activities are expected to provide greater access to more comprehensive care.The objective of this paper is to assess the impact of TB/HIV integration on TB treatment outcomes and to explore the usefulness of TB treatment outcomes as TB/HIV indicators.Methods:A before-and-after study to observe the introduction of TB/HIV activities into TB programmes in three hospitals with different levels of integration was conducted.Anonymised patient data was collated from TB registers from each facility,and analysed to determine if TB treatment outcomes changed significantly after integration.Results:TB treatment success was 50%(95%CI 49-52)prior to,and 69%(95%CI 65-73)after,integration(Χ243.96,p<0.00).Treatment success increased from 43%to 53%at the one-stop shop(OSS),from 69%to 78%at the partially integrated site(PIS)and substantially from 46%to 78%at the referral site(RS)(Χ264.54;p<0.01).Defaults and cases transferred out reduced from 14.3%and 15.3%prior to integration,to 1.4%and 9.0%after integration,respectively,accounting for a significant increase in treatment success.Death rates remained high at 18%in all cases studied and 25%in HIV-associated cases after integration.Conclusion:TB/HIV integration may improve TB treatment success,but its exact impact is difficult to ascertain due to non-specificity and design limitations.TB mortality may be more useful as an indicator for monitoring TB/HIV activities in Ghana. | Gloria Akosua Ansa John D Walley Kamran Siddiqi Xiaolin Wei | 2012 | Infectious Diseases of Poverty2012,1,1: | 4 |
| 3 | Review of experimental techniques for high rate deformation and shock studies显示文摘 | J.E. Field S.M. Walley W.G. Proud H.T. Goldrein C.R. Siviour | 2004 | International Journal of Impact Engineering2004,,7: | 3 |
| 4 | Vasopressin versus norepinephrine infusion in patients with septic shock显示文摘 | Russell JA Walley KR Singer J | | 0,,09: | 2 |
| 5 | Topographic Indices and Yield Variability in a Rolling Landscape of Western Canada显示文摘Understanding the relationships between topographic indices and crop yield variability is important for soil manage- ment and crop production in rolling landscape. Two agricultural fields at Alvena and Hepburn, Saskatchewan, Canada were selected to examine how topographic indices were related to wheat yield under two topographic and weather conditions in the Canadian prairies. The landscapes of the two sites are classified as hummocky and the dominant soil type is an Aridic Ustoll. The relationships among yield, topography, soil, and weather were analyzed using wheat (Triticum aestivum L.) grain yield from Alvena in 2001 (dry year) and 2004 (wet year) and from Hepburn in 1998 (dry year). Topographic/soil indices included relative elevation, wetness index, upslope length, curvature, soil organic matter, and soil moisture storage before seeding. The results indicated that, in the dry years, the correlation coefficients between upslope length and grain yield were 0.79 for the typical rolling landscape (Alvena) in 2001 and 0.73 for shallow gentle rolling landscape (Hepburn) in 1998. In the wet year (2004), the relationships between yield and topographic/soil attributes were not as strong as in dry years. Therefore, upslope length was the best yield indicator for the two landscapes in dry years, whereas no topographic indices were highly correlated to crop yield in wet years. Those topographic indices seemed useful in identifying the yield variability and delineating the proper management zone. | CHI Bao-Liang BING Cheng-Si F. WALLEY T. YATES | 2009 | Pedosphere2009,19,3: | 2 |
| 6 | Using no-cost mobile phone reminders to improve attendance for HIV test results: a pilot study in rural Swaziland显示文摘Background:Mobile technology has great potential to improve adherence and treatment outcomes in healthcare settings.However,text messaging and phone calls are unaffordable in many resource-limited areas.This study investigates the use of a no-cost alternative mobile phone technology using missed calls(‘buzzing’)to act as a patient reminder.The use of missed calls as a patient reminder was evaluated for feasibility and effectiveness as an appointment reminder in the follow-up of newly-diagnosed human immunodeficiency virus(HIV)positive patients in an HIV testing and counselling department in rural Swaziland.Methods:This pilot study uses a before-and-after operational research study design,with all patients with mobile phones being offered the intervention.The primary outcome was the rate of attendance at the HIV testing and counselling department for collection of results in those with mobile phones before and after the introduction of the intervention.Results:Over two-thirds,71.8%(459/639),of patients had a mobile phone.All patients with a mobile phone consented to being buzzed.There was no difference in attendance for follow-up at the clinic before and after the intervention was implemented(80.1%versus 83.3%,p=0.401),or after adjusting for confounding factors(OR 1.13,p=0.662).Conclusion:This pilot study illustrates that mobile technology may be feasible in rural,resource-poor settings as there are high rates of mobile phone ownership and the intervention had a 100%uptake rate,with positive feedback from staff and patients.In this particular setting,the intervention did not improve attendance rates.However,further research is planned to investigate the impact on adherence to appointments and medications in other settings,such as HIV chronic care follow-up and as part of an enhanced package to improve adherence. | Merav Kliner Abigail Knight Canaan Mamvura John Wright John Walley | 2013 | Infectious Diseases of Poverty2013,2,1: | 2 |
| 7 | Particle size effects on the mechanical properties of a polymer bonded explosive显示文摘 | Siviour C R Gifford M J Walley S M | 2004 | J Mater Sci2004,39,4: | 1 |
| 8 | It is Not Easy Being Green 显示文摘 | WALLEY N WHITEHEAD B | 1994 | Harvard Business Review1994,72,3: | 1 |
| 9 | Nitric oxide reduces the sequestration of polymorphonuclear leukocytes in lung by changing deformability and CD18 expression显示文摘 | Sato Y Walley KR Klut ME | 1999 | Am J Respir Crit Care Med1999,159,: | 1 |
| 10 | Plant growth- promoting rhi- zobacteria alter rooting patterns and arbuscular mycorrhizal fungi colonization of field - grown spring wheat 显示文摘 | Gerrnida J J walley F L | 1996 | Biol Fertil Soils1996,23,2: | 1 |
| 11 | Vasopressin versus norepinephrine infusion in patients with septic shock显示文摘 | Russell JA Walley KR Singer J | | 0,,09: | 1 |
| 12 | Particle Size Effects on the Mechanical Properties of a Polymer Bonded Explosive显示文摘 | Siviour C R Gifford M J Walley S M | 2004 | J Materials Science2004,39,: | 1 |
| 13 | It' s Not Easy Being Green 显示文摘 | Walley N Whitehead B | 1994 | The Earthscan Reader in Business and the Environment1994,5,6: | 1 |
| 14 | Is there a role for sodium bicarbonate in treating lactic acidosis from shock显示文摘 | Boyd JH Walley KR | | 0,,04: | 1 |
| 15 | A review, synthesis and interpretation of the literature on competitive advantage 显示文摘 | WALLEY K THWAITES D | 1996 | Journal of strategic marketing1996,,4: | 1 |
| 16 | Tuberculosis in Pakistan:Socio -cultural constrains and opportunities in treatment显示文摘 | Kahn A Walley J Newell J | 2000 | Soc Sci Med2000,50,2: | 1 |
| 17 | Modulation of proinflammatory cytokines by nitric oxide in murine acute lung injury显示文摘 | Walley KR McDonald TE Higashimoto Y | 1999 | Am J Respir Crit Care Med1999,160,2: | 1 |
| 18 | Interaction of vasopressin infusion,corticosteroid treatment,and mortality of septic shock显示文摘 | Russell JA Walley KR Gordon AC | | 0,,03: | 1 |
| 19 | Relationships between soil nitrogen availability indices, yield, and nitrogen accumulation of wheat显示文摘 | Walley F Yates T Groenigen J W | 2002 | Soil Science Society of America Journal2002,66,5: | 1 |
| 20 | Quality of Medication Use in Primary Care-mapping the Problem, Working to a Solution: a Systematic Review of the Literature显示文摘 | Garfield S Barber N Walley P | 2009 | BMC Med2009,7,: | 1 |