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| 1 | Differing coping mechanisms, stress level and anorectal physiology in patients with functional constipation显示文摘AIM: To investigate coping mechanisms, constipation symptoms and anorectal physiology in 80 constipated subjects and 18 controls.METHODS: Constipation was diagnosed by Rome Ⅱ criteria.Coping ability and anxiety/depression were assessed by validated questionnaires. Transit time and balloon distension test were performed.RESULTS: 34.5% patients were classified as slow transit type of constipation. The total colonic transit time (56 h vs 10 h, P<0.0001) and rectal sensation including urge sensation (79 mL vs 63 mL, P = 0.019) and maximum tolerable volume (110 mL vs95 mL, P = 0.03) differed in patients and controls. Constipated subjects had significantly higher anxiety and depression scores and lower SF-36 scores in all categories. They also demonstrated higher scores of'monitoring' coping strategy (14+6 vs9+3, P = 0.001),which correlated with the rectal distension sensation (P = 0.005), urge sensation (P=0.002), and maximum tolerable volume (P = 0.035). The less use of blunting strategy predicted slow transit constipation in both univariate (P = 0.01) and multivariate analysis (P = 0.03).CONCLUSION: Defective or ineffective use of coping strategies may be an important etiology in functional constipation and subsequently reflected in abnormal anorectal physiology. | Annie OO Chan Cecilia Cheng Wai Mo Hui Wayne HC Hu Nina YH Wong KF Lam Wai Man Wong Kam Chuen Lai Shiu Kum Lam Benjamin CY Wong | 2005 | World Journal of Gastroenterology2005，11，34： | 92 |
| 2 | 世界胃肠病学组织(WGO-OMGE)临床指南——发展中国家幽门螺杆菌感染显示文摘我非常高兴向大家推荐这份发展中国家幽门螺杆菌(H.priori)临床指南。该指南的编译是由数位在该领域具有丰富临床经验的世界知名专家共同完成的。 | Hunt RH Xiao SD Megraud F Leon-Barua R Bazzoli F Van der Merwe S vaz Coelho LG Fock KM Fedail S Cohen H Malfertheiner P Vakil N Hamid S Goh KL Wong BC Krabshuis JH 杜颖 丛衍群 戴宁 | 2007 | 胃肠病学2007，12，1： | 85 |
| 3 | KaKs_Calculator:Calculating Ka and Ks Through Model Selection and Model Averaging显示文摘KaKs_Calculator is a software package that calculates nonsynonymous (Ka) andsynonymous (Ks) substitution rates through model selection and model averag-ing. Since existing methods for this estimation adopt their specific mutation(substitution) models that consider different evolutionary features, leading todiverse estimates, KaKs Calculator implements a set of candidate models in amaximum likelihood framework and adopts the Akaike information criterion tomeasure fitness between models and data, aiming to include as many featuresas needed for accurately capturing evolutionary information in protein-coding se-quences. In addition, several existing methods for calculating Ka and Ks arealso incorporated into this software. KaKs Calculator, including source codes,compiled executables, and documentation, is freely available for academic use athttp://gffzz5c65aa98f6514e89hwuvqqbkxq5ou6owc.ffgz.tsg.suse.edu.cn/software.htm. | Zhang Zhang Jun Li Xiao-Qian Zhao Jun Wang Gane Ka-Shu Wong Jun Yu | 2006 | Genomics, Proteomics & Bioinformatics2006，4，4： | 86 |
| 4 | 沁水盆地南部注二氧化碳提高煤层气采收率微型先导性试验研究显示文摘在沁水盆地南部TL-003井进行了单井注入CO2提高煤层气采收率试验。采用间歇式注入方式,共向3号煤层注入192.8t液态CO2。生产和储层模拟评价结果表明,大部分CO2被煤层吸附,能显著提高单井产量和采收率。多井试验模拟显示,在沁南无烟煤煤层中注入CO2,能显著地提高煤层气采收率,同时实现了埋藏CO2的目标。 | 叶建平 冯三利 范志强 王国强 William D.Gunter Sam Wong John R.Robinson | 2007 | 石油学报2007，28，4： | 88 |
| 5 | 综合医院住院病人满意度量表研制初报显示文摘为客观地以服务对象为主体评价综合医院的医疗服务质量,本研究初步研制了住院病人满意度量表(IPSO),通过预调查数据,对量表作为一种测量工具进行了较系统的科学评价,以广州市3所综合医院的900例出院病人为调查对象,采用信函调查方式,初测有效回收率为30%,再测有效回收率为47%,项目应答率为93.2%。内部一致性α信度系数颇高,为0.92;初测与再测之间无显著性差异(P=0.183),且密切相关(r=0.812,P<0.0001),重测信度满意。经因予分析,因予负荷和结构与量表内容基本吻合,支持内容效度。因素内相关性强于因素间相关性的结果,有力地支持聚集和区分效度,可以初步认为,IPSO是可信的和有效的。 | 陈平雁 Chit-Ming Wong 区燕萍 胡静 张超 梁丽萍 蔡湛宇 | 1999 | 中国医院管理1999，19，2： | 155 |
| 6 | 中国妇女妊娠前后单纯服用叶酸对神经管畸形的预防效果显示文摘目的 评价妇女在妊娠前后服用单纯 40 0 μg叶酸增补剂对胎 /婴儿神经管畸形 (NTDs)的预防效果。方法 1993~ 1995年在中国北方的NTDs高发地区和南方的NTDs低发地区妇女增补叶酸的推广项目中 ,共募集从孕前或孕后任何时间开始服药的妇女 130 142名 ,未服药的妇女 1176 89名 ;设计的服药方法从婚检时开始到孕满 3个月为止 ,每天服用单纯叶酸片 40 0 μg ;最后对妇女的分娩结局进行监测并进行预防效果的对比评价研究。结果 服药组妇女生育的胎婴儿中共发现 10 2例NTDs ,对照组胎婴儿中共发现 173例NTDs。末次月经前募集的未服药妇女在孕 2 0周以后分娩的胎婴中NTDs发生率 ,北方为 4 8‰ (16 / 3 318) ,南方为 1 0‰ (2 8/ 2 82 6 5 ) ,而妊娠前后服药妇女组则分别为1 0‰ (13/ 13 0 12 )和 0 6‰ (34/ 5 86 38)。与末次月经前募集的未服药妇女组相比 ,北方服药妇女NTDs发生率明显降低 ,其中依从性大于 80 %的服药组妇女预防率达 85 % (95 %CI为 6 2 %~ 94% ) ,南方地区服叶酸的预防率为 41% (95 %CI为 3 %~ 6 4% )。结论 妇女在妊娠前后每天服用单纯叶酸 40 0 | 李竹 RobertJ Berry 李松 J David Erickson 王红 Cynthia A Moore 赵平 Joseph Mulinare 洪世欣 Lee-Yang C Wong 呼和牧人 Jacqueline Gindler 郝玲 Adolfo Correa 朱慧萍 Elaine Gunter | 2000 | 中华医学杂志2000，80，7： | 185 |
| 7 | Extensive translation of circular RNAs driven by N6-methyladenosine显示文摘广泛的 pre-mRNA 拼接背在人的 transcriptome 产生众多的圆形的 RNA (circRNAs ) 。然而,这些 circRNAs 的生物功能仍然保持大部分不清楚。这里,我们报导那 N 6-methyladenosine (m 6 一) , RNA 的最丰富的基础修正,在人的房间从 circRNAs 支持蛋白质翻译的有效开始。我们发现那一致 m 6 A 主题在 circRNAs 和单个 m 6 一个地点是足够的驾驶翻译开始。这 m 6A 驱动的翻译要求开始因素 eIF4G2 和 m 6 读者 YTHDF3,并且被 methyltransferase METTL3/14 提高,在热吃惊之上由 demethylase FTO,和 upregulated 禁止了。通过介绍的 polysome 的进一步的分析,计算预言和集体 spectrometry 揭示那 m 6 circRNAs 的 A 驱动的翻译是普遍的,与有翻译潜力的几百内长的 circRNAs。我们的学习扩展人的 transcriptome 的编码风景,并且在对环境应力的细胞的回答建议导出 circRNA 的蛋白质的一个角色。 | Yun Yang Xiaojuan Fan Miaowei Mao Xiaowei Song Ping Wu6,7 Yang Zhang Yongfeng Jin Yi Yang Ling-Ling Chen Yang Wang Catherine CL Wong Xinshu Xiao Zefeng Wang | 2017 | Cell Research2017，27，5： | 246 |
| 8 | A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01)显示文摘The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-associated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs. We report the complete genome sequence and comparative analysis of an isolate (BJ01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 2 ORFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS- associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to beinvolved in the immunoreactions between the virus and its host. Two amino acid changes have been detected in the Mprotein, which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides noevidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of otherpossible SARS-related pathogen(s). | QIN E'de ZHU Qingyu YU Man FAN Baochang CHANG Guohui SI Bingyin YANG Bao PENG Wenming JIANG Tao LIU Bohua DENG Yongqiang LIU Hong ZHANG Yu WANG Cui LI Yuquan GAN Yonghua LI Xiaoyu L Fushuang TAN Gang CAO Wuchun, YANG Ruifu Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China WANG Jian, LI Wei, XU Zuyuan, LI Yan, WU Qingfa, LIN Wei, CHEN Weijun, TANG Lin, DENG Yajun, HAN Yujun, LI Changfeng, LEI Meng, LI Guoqing, LI Wenjie, L Hong, SHI Jianping, TONG Zongzhong, ZHANG Feng, LI Songgang, LIU Bin, LIU Siqi, DONG Wei, WANG Jun, Gane K-S Wong, YU Jun & YANG Huanming* Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300 National Center for Genome Information, Beijing 101300, China | 2003 | Chinese Science Bulletin2003，48，10： | 121 |
| 9 | Heart-type fatty acid binding protein (H-FABP) as a biomarker for acute myocardial injury and long-term post-ischemic prognosis显示文摘尖锐心肌的梗塞(AMI ) 是一个威胁生活的事件。甚至与及时处理,尖锐 ischemic 心肌的损害和随后的局部缺血灌注损害(IRI ) 能仍然是困难的问题处理。除了放射学并且另外的辅助考试,适用的心脏的 biomarkers 的实验室测试为这混乱监视的早诊断和结束也是必要的。心类型丰满的酸绑定蛋白质(H-FABP ) 主要在 cardiomyocytes 内存在,最近为心肌的损害作为潜在地有希望的 biomarker 出现了。在这评论,我们在对心肌的损害和 IRI 的评价讨论 H-FABP 的敏感和特性,特别在早阶段,和它与另外的通常使用的心脏的 biomarkers 比较的长期的预示的价值,包括肌球素( Mb ),心脏的 troponin 我( cTnI ),肌酸 kinase MB ( CK-MB ),C反应的蛋白质( CRP ),肝糖 phosphorylase isoenzyme BB ( GPBB ),和高敏感的心脏的 troponin T ( hs-cTnT )。有另外的 biomarkers 的 H-FABP 的联合申请的潜力和值也被讨论。最后, H-FABP 的前景被总结;几个技术问题被讨论在临床的实践便于 H-FABP 的更宽的申请。 | Xiao-dong YE Yi HE Sheng WANG Gordon T WONG Michael G IRWIN Zhengyuan XIA | 2018 | Acta Pharmacologica Sinica2018，39，7： | 72 |
| 10 | The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis显示文摘上皮间充质的转变(EMT ) 把上皮的肿瘤房间变换成侵略、变形的癌症房间,导致在癌症病人的死亡。尽管扭曲为胸和另外的癌症是 EMT 和转移的一个主人管理者,为调停扭曲的基因抄写负责的机制仍然保持未知。在这研究, TWIST 蛋白质建筑群的纯化和描述表明那扭曲与改变的 Mi2/nucleosome 和 deacetylase (Mi2/NuRD ) 的几个部件交往建筑群, MTA2, RbAp46, Mi2 和 HDAC2,和成员他们到为 transcriptional 压抑的 E-cadherin 倡导者的近似区域。从取决于的房间线高效地为转移扭曲的癌症的这些扭曲建筑群部件的弄空在老鼠在文化和肺转移压制房间移植和侵略。这些调查结果不仅提供在扭曲和 Mi2/NuRD 建筑群之间的新奇机械学、功能的连接而且为在癌症复杂的 Mi2/NuRD 的部件建立新必要角色转移。 | Junjiang Fu Li Qin Tao He Jun Qin Jun Hong Jiemin Wong Lan Liao Jianming XU | 2011 | Cell Research2011，21，2： | 51 |
| 11 | 中文大学生版Buss-Perry攻击性量表的修订与信效度分析显示文摘目的:引进Buss-Perry攻击性量表(BPAQ),并在大学生群体中进行修订,用来测量我国大学生的攻击性水平。方法:在不同行政区域的9所综合型大学抽取1722名在校大学生。对样本编号后,奇数组(n=864)被用于探索性因素分析以确认因子结构;偶数组(n=858)被用于对所得维度进行验证性因素分析。用大学生社会技能量表(ChUSSI)和羞涩量表(RCBS)为效标。抽取其中一所大学的165名学生于初评后2周进行重测。结果:通过探索性因素分析,得到由敌意、身体攻击、冲动、易怒性4个分量表(共22个项目)构成的中文大学生版Buss-Perry攻击性量表(CC-BPAQ);验证性因素分析显示数据拟合良好(GFI=0.917,AGFI=0.896,CFI=0.899,RMSEA=0.059);CC-BPAQ的敌意、身体攻击和易怒性分量表得分与ChUSSI得分呈负相关(r=-0.23、-0.19、-0.20,均P<0.01),CC-BPAQ的4个分量表得分均与RCBS得分呈正相关(r=0.45、0.21、0.11、0.32,均P<0.01)。总量表的内部一致性Cronbachα系数为0.89,4个分量表的α系数为0.73~0.85;总量表的重测信度为0.91,4个分量表的重测信度为0.75~0.80。结论:修订后的中文大学生版Buss-Perry攻击性量表具有良好的信度和效度,可以用于大学生的攻击性测量。 | 吕路 高见和至 董冬 WONG Law rence 王翕 | 2013 | 中国心理卫生杂志2013，27，5： | 52 |
| 12 | Chaperone-mediated autophagy: roles in disease and aging显示文摘这评论集中于调停女伴的 autophagy (CMA ) ,在 lysosomes 贡献细胞内部的蛋白质的降级的解朊的系统之一。CMA 底层蛋白质有选择地通过在膜和奉献蛋白质 translocation 建筑群的双方定位的女伴的协调行动被指向到 lysosomes 和 translocated 进 lysosomal 腔。CMA 许可证的选择与在细胞的 transcriptional 程序的酶的新陈代谢的进程和子集为 CMA 支持一个调节角色的规章的目的预定了特定的蛋白质的降级。另外, CMA 通过移动贡献细胞的质量控制损坏或失灵蛋白质。这里,我们在 CMA 的分子的动力学,规定和生理学的理解描述最近的进展,并且在对象 neurodegeneration 和癌症那样的严重人的混乱的 CMA 机能障碍的贡献的支持讨论证据。 | Ana Maria Cuervo Esther Wong | 2014 | Cell Research2014，24，1： | 57 |
| 13 | Variations between rice cultivars in iron and manganese plaque on roots and the relation with plant cadmium uptake显示文摘To understand certain mechanisms causing variations between rice cultivars with regard to cadmium uptake and tolerance,pot soil experiments were conducted with two rice cultivars of different genotypes under different soil Cd levels.The relationships between plant Cd uptake and iron/manganese(Fe/Mn) plaque formation on roots were investigated.The results showed that rice cultivars di?ered markedly in Cd uptake and tolerance.Under soil Cd treatments,Cd concentrations and accumulations in the cultivar Shanyou 63(the genotype indica) were significantly higher than those in the cultivar Wuyunjing 7(the genotype japonica)(P < 0.01,or P < 0.05),and Shanyou 63 was more sensitive to Cd toxicity than Wuyunjing 7.The differences between the rice cultivars were the largest at relatively low soil Cd level(i.e.,10 mg/kg).Fe concentrations in dithionite-citrate-bicarbonate root extracts of Shanyou 63 were generally lower than that of Wuyunjing 7,and the difference was the most significant under the treatment of 10 mg Cd/kg soil.The results indicated that the formation of iron plaque on rice roots could act as a barrier to soil Cd toxicity,and may be a 'buffer' or a 'reservoir' which could reduce Cd uptake into rice roots.And the plaque may contribute,to some extent,to the genotypic differences of rice cultivars in Cd uptake and tolerance. | Jianguo Liu Changxun Cao Minghung Wong Zhijun Zhang Yuhong Chai | 2010 | Journal of Environmental Sciences2010，22，7： | 43 |
| 14 | 中国儿童孤独症谱系障碍患病率的系统综述(英文)显示文摘背景中国孤独症和孤独症谱系障碍(autism spectrum disorders,ASD)的患病率缺乏可靠的估计。目的运用Meta分析综合评价中国18岁以下人群孤独症和ASD患病情况,并分析其在性别、民族、城乡等不同因素间的差异。方法检索中国知识资源总库、中国科技期刊数据库、万方数据检索系统、中国生物医学文摘数据库、PubMed和Web of Science等数据库,收集关于中国孤独症谱系障碍患病率的文献,按照预先制定的纳入及排除标准筛选相关研究。采用R-2.1 5.2软件对资料进行统计学分析。结果共纳入24项研究,其中5项来自香港和台湾的注册研究(涉及14,570,369名儿童),19项来自大陆以人群为基础的筛查和诊断研究(合并样本量为771,413名儿童)。港台注册研究报道的孤独症年患病率为1.8~424.6/10,000。中国大陆的18项研究(剔除一个患病率最低的全国性研究)报道孤独症患病率为2.8~30.4/10,000,合并后孤独症患病率为12.8/10,000(95%CI,9.4~17.5)。5项研究报道ASD(患病率为7.3~75.3/10,000)合并后患病率24.5/10,000(95%CI,10.4~57.4)。不同性别、居住地点、发表时间和抽样来源之间报道的患病率存在明显差异。结论港台注册研究报道的孤独症患病率存着巨大差异(达200倍),大陆以人群为基础的筛查诊断研究报道的患病率存在较大差异(10~15倍),凸显迫切需要建立标准的方法来估计孤独症和ASD的患病率。只有方法学质量得到改善,才有可能为这些不常见但严重致残的疾病提供循证的防治策略。 | 万玉美 胡强 李婷 姜丽娟 杜亚松 Lei FENG John Chee-Meng WONG 李春波 | 2013 | 上海精神医学2013，25，2： | 45 |
| 15 | Phytochemistry,pharmacology,and clinical trials of Morus alba显示文摘The present review is aimed at providing a comprehensive summary on the botany,utility,phytochemistry,pharmacology,and clinical trials of Morus alba(mulberry or sang shu).The mulberry foliage has remained the primary food for silkworms for centuries.Its leaves have also been used as animal feed for livestock and its fruits have been made into a variety of food products.With flavonoids as major constituents,mulberry leaves possess various biological activities,including antioxidant,antimicrobial,skin-whitening,cytotoxic,anti-diabetic,glucosidase inhibition,anti-hyperlipidemic,anti-atherosclerotic,anti-obesity,cardioprotective,and cognitive enhancement activities.Rich in anthocyanins and alkaloids,mulberry fruits have pharmacological properties,such as antioxidant,anti-diabetic,anti-atherosclerotic,anti-obesity,and hepatoprotective activities.The root bark of mulberry,containing flavonoids,alkaloids and stilbenoids,has antimicrobial,skin-whitening,cytotoxic,anti-inflammatory,and anti-hyperlipidemic properties.Other pharmacological properties of M.alba include anti-platelet,anxiolytic,anti-asthmatic,anthelmintic,antidepressant,cardioprotective,and immunomodulatory activities.Clinical trials on the efficiency of M.alba extracts in reducing blood glucose and cholesterol levels and enhancing cognitive ability have been conducted.The phytochemistry and pharmacology of the different parts of the mulberry tree confer its traditional and current uses as fodder,food,cosmetics,and medicine.Overall,M.alba is a multi-functional plant with promising medicinal properties. | Eric Wei-Chiang CHAN Phui-Yan LYE Siu-Kuin WONG | 2016 | Chinese Journal of Natural Medicines2016，14，1： | 40 |
| 16 | Nat Genet:单细胞分析解开结直肠癌细胞的神秘面纱显示文摘结合单细胞基因组学和计算机技术,一个研究团队(包括来自杰克逊实验室(JAx)单细胞生物学主任Paul Robson博士在内)鉴定出了11种结直肠癌肿瘤的癌细胞组成及邻近的非癌细胞。这对于更好的肿瘤靶向诊断和治疗很重要。”使用单细胞测序。”JAX科学家、这篇发表在Nature Genetics上的文章共同第一作者Elise Courtois说道。”我们可以根据肿瘤中的细胞组成将结直肠癌进一步分类。因为每种亚型的肿瘤病人生存率存在差别,我们的方法将为肿瘤医生提供更多的关于肿瘤预后和治疗的信息。” | Huipeng Li, Elise T Courtois, Debarka Sengupta, Yuliana Tan Shyam Prabhakar Elise T Courtois, Yuliana Tan Paul Robson Debarka Sengupta Kok Hao Chen, Jolene Jie Lin Goh Paul Jongjoon Choi Say Li Kong, Axel M Hillmer Iain Beehuat Tan Clarinda Chua Iain Beehuat Tan Lim Kiat Hon Wah Siew Tan Mark Wong Lawrence J K Wee Iain Beehuat Tan Paul Robson Paul Robson Paul Robson | 2017 | 现代生物医学进展2017，17，15： | 37 |
| 17 | Guidelines for evaluation and management of cerebral collateral circulation in ischaemic stroke 2017显示文摘Collateral circulation plays a vital role in sustaining blood flow to the ischaemic areas in acute,subacute or chronic phases after an ischaemic stroke or transient ischaemic attack.Good collateral circulation has shown protective effects towards a favourable functional outcome and a lower risk of recurrence in stroke attributed to different aetiologies or undergoing medical or endovascular treatment.Over the past decade,the importance of collateral circulation has attracted more attention and is becoming a hot spot for research.However,the diversity in imaging methods and criteria to evaluate collateral circulation has hindered comparisons of findings from different cohorts and further studies in exploring the clinical relevance of collateral circulation and possible methods to enhance collateral flow.The statement is aimed to update currently available evidence and provide evidence-based recommendations regarding grading methods for collateral circulation,its significance in patients with stroke and methods under investigation to improve collateral flow. | Liping Liu Jing Ding Xinyi Leng Yuehua Pu Li-An Huang Anding Xu Ka Sing Lawrence Wong Xin Wang Yongjun Wang 无 | 2018 | Stroke & Vascular Neurology2018，3，3： | 37 |
| 18 | 山西沁水盆地柿庄北区块3#煤层注入埋藏CO_2提高煤层气采收率试验和评价显示文摘对沁水盆地南部柿庄北区块进行了深煤层注入地质和工程评价,认为柿庄北区块适合进行深煤层注入CO2开采煤层气技术的应用;通过SX-001井的微型先导性试验,对SX-001井的注入前后产气量与产水量、气体成分变化和井底压力变化规律进行了总结。通过现场试验,注入CO2后SX-001井的产气量是注入前的2.45倍;在小于煤岩破裂压力的条件下,每天注入20 t的CO2能够实现顺利注入,并且压力上升速度较慢;注入CO2后,煤岩发生膨胀,局部煤层的渗透率降低,排采一段时间后恢复;在目的煤层中注入的CO2的影响范围内,烃类气体总的置换效率达到14.18 cm3/g。该试验成果证明柿庄北区块通过注入CO2开采煤层气实现了CO2的埋藏,提高了煤层气井的采收率。 | 叶建平 张兵 Sam Wong | 2012 | 中国工程科学2012，14，2： | 33 |
| 19 | 古村落景区游客拥挤感知维度与游憩情绪影响机制研究--以西递、宏村为例显示文摘拥挤感知被认为是影响游客的游憩体验和满意度的重要指标,通过构建拥挤感知的多维度变化来探讨游客情绪的变化对满意度的影响研究仍不成熟。本文以西递、宏村为研究案例地,运用结构方程模型分析方法,构建空间拥挤、人潮拥挤和体验拥挤维度对游客游憩过程的影响模型,探讨了游客拥挤三个维度的影响因素。研究表明:(1)人潮拥挤对情感依附型游客积极情绪呈正向影响;(2)空间拥挤增加消极情绪,与游客满意度呈负相关关系;(3)体验拥挤对游客积极情绪呈显著负向影响;(4)人潮拥挤—积极情绪—满意度(0.359)之间的相互关系强于人潮拥挤—消极情绪—满意度(0.128);空间拥挤—积极情绪—游客满意度(-0.241)的关联度强于空间拥挤—消极情绪—游客满意度(-0.142);体验拥挤—积极情绪—游客满意度(-0.167)之间的影响关系弱于体验拥挤—消极情绪—游客满意度(-0.213);(5)人口特征对拥挤感知的影响差异显著。 | 张圆刚 余向洋 Wong IpKin Anthony 程静静 尹寿兵 | 2018 | 人文地理2018，33，2： | 34 |
| 20 | Response of microbial communities to biochar-amended soils:a critical review显示文摘Application of biochar to soils changes soil physicochemical properties and stimulates the activities of soil microorganisms that influence soil quality and plant performance.Studying the response of soil microbial communities to biochar amendments is important for better understanding interactions of biochar with soil,as well as plants.However,the effect of biochar on soil microorganisms has received less attention than its influences on soil physicochemical properties.In this review,the following key questions are discussed:(i)how does biochar affect soil microbial activities,in particular soil carbon(C)mineralization,nutrient cycling,and enzyme activities?(ii)how do microorganisms respond to biochar amendment in contaminated soils?and(iii)what is the role of biochar as a growth promoter for soil microorganisms?Many studies have demonstrated that biochar-soil application enhances the soil microbial biomass with substantial changes in microbial community composition.Biochar amendment changes microbial habitats,directly or indirectly affects microbial metabolic activities,and modifies the soil microbial community in terms of their diversity and abundance.However,chemical properties of biochar,(especially pH and nutrient content),and physical properties such as pore size,pore volume,and specific surface area play significant roles in determining the efficacy of biochar on microbial performance as biochar provides suitable habitats for microorgan-isms.The mode of action of biochar leading to stimulation of microbial activities is complex and is influenced by the nature of biochar as well as soil conditions. | Kumuduni Niroshika Palansooriya James Tsz Fung Wong Yohey Hashimoto Longbin Huang Jörg Rinklebe Scott X.Chang Nanthi Bolan Hailong Wang Yong Sik Ok | 2019 | Biochar2019，1，1： | 34 |
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