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| 1 | Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis显示文摘AIM:To test the hypothesis that liver cirrhosis is associated with mobilization of hematopoietic progenitor cells. METHODS:Peripheral blood samples from 72 patients with liver cirrhosis of varying etiology were analyzed by flow cytometry.Identified progenitor cell subsets were immunoselected and used for functional assays in vitro. Plasma levels of stromal cell-derived factor-1(SDF-1) were measured using an enzyme linked immunosorbent assay.RESULTS:Progenitor cells with a CD133 + /CD45 + CD14 + phenotype were observed in 61%of th patients.Between 1%and 26%of the peripheral bloo mononuclear cells(MNCs)displayed this phenotype Furthermore,a distinct population of c-kit + progenito cells(between 1%and 38%of the MNCs)could b detected in 91%of the patients.Additionally,18% of the patients showed a population of progenito cells(between 1%and 68%of the MNCs)that wa characterized by expression of breast cancer resistanc protein-1.Further phenotypic analysis disclosed tha the circulating precursors expressed CXC chemokin receptor 4,the receptor for SDF-1.In line with thi finding,elevated plasma levels of SDF-1 were presen in all patients and were found to correlate with th number of mobilized CD133 + progenitor cells. | Ursula M Gehling Marc Willems Kathleen Schlagner Ralf A Benndorf Maura Dandri Jrg Petersen Martina Sterneck Joerg-Matthias Pollok Dieter K Hossfeld Xavier Rogiers | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 2 | 环境中的药物——LC-MS/MS分析地表水和地下水显示文摘 | Alida(Linda)AM Stolker Willem Niesing Frank Bakker Johanna(Ans)FM Versteegh Elbert A Hogendoorn Udo A Th Brinkman | 2007 | 环境化学2007，26，4： | 4 |
| 3 | Colonic stenting versus emergency surgery for acute left-sided malignant colonic obstruction: a multicentre randomised trial显示文摘 | Jeanin E van Hooft Willem A Bemelman Bas Oldenburg Andreas W Marinelli Martijn F Lutke Holzik Marina J Grubben Mirjam A Sprangers Marcel G Dijkgraaf Paul Fockens | 2011 | Lancet Oncology2011，，4： | 3 |
| 4 | Quality of life after laparoscopic and open colorectal surgery: A systematic review显示文摘This study was a systematic review of the available evidence on quality of life in patients after laparoscopic or open colorectal surgery. A systematic review was performed of all randomized clinical trials (RCTs) that compared laparoscopic with open colorectal surgery. Study selection, quality assessment and data extraction were carried out independently by two reviewers. Primary endpoint was quality of life after laparoscopic and open colorectal surgery, as assessed by validated questionnaires. The search resulted in nine RCTs that included 2263 patients. Shortand long-term results of these RCTs were described in 13 articles. Postoperative follow-up ranged from 2 d to 6.7 years. Due to clinical heterogeneity, no meta-analysis could be conducted. Four RCTs did not show any difference in quality of life between laparoscopic or open colorectal surgery. The remaining five studies reported a better quality of life in favor of the laparoscopic group on a few quality of life scales at time points ranging from 1 wk to 2 years after surgery. In conclusion, based on presently available high-level evidence, this systematic review showed no clinically relevant differences in postoperative quality of life between laparoscopic and open colorectal surgery. | Sanne AL Bartels Malaika S Vlug Dirk T Ubbink Willem A Bemelman | 2010 | World Journal of Gastroenterology2010，16，40： | 3 |
| 5 | Modeling piezoelectric actuators显示文摘 | Willem L | 2000 | IEEE/ASME Transactions on Mechatronics2000，5，4： | 1 |
| 6 | Passivity, feedback equivalence, and the global stabilization of minimum phase nonlinear systems显示文摘 | Byrnes C I Isidori A Willems J C | 1998 | IEEE Trans on Automatic Control1998，36，11： | 1 |
| 7 | Preparation and characterization of Carbon Nanotube/Polyacrylonitrile Composites显示文摘 | Pirlot C Willems I Fonseca A | 2002 | Adv Eng Mater2002，4，3： | 1 |
| 8 | Passivity, feedback equivalence and the global stabilization of minimum phase nonlinear systems显示文摘 | Byrnes C Isidori A Willems J | 1991 | IEEE Trans Autom Control1991，36，11： | 1 |
| 9 | Passivity,feedback equivalence,and global stabilization of minimum phase nonlinear systems显示文摘 | Byrnes C I Isidori A Willems J C | 1991 | IEEE Trans Automat Control1991，36，11： | 1 |
| 10 | Antimicrobial peptides from plants显示文摘 | Willem F B Cammue B P A De Bone M F C | 1997 | Critical Reviews in Plant Sciences1997，16，3： | 1 |
| 11 | Classification of 6-dimensional nilpotent Lie algebras over fields of characteristic not 2 显示文摘 | Willem A de Graaf | 2007 | Journal of Algebra2007，309，： | 1 |
| 12 | Cullinbasedubiquitinligases:Cul3BTB complexes join the family显示文摘 | Pintard L Willem A Peter M | 2004 | EMBO J2004，23，8： | 1 |
| 13 | Social capital and political bias in knowledge sharing:an exploratory study显示文摘 | WILLEM A SCARBROUGH H | | 0，，10： | 1 |
| 14 | Study on the transformation of intact yeast cells by LiAc/SS-DNA/ PEG procedure 显示文摘 | Gietz R D Schiestl R H Willems A R | 1995 | Yeast1995，11，4： | 1 |
| 15 | Passivity,feedback equivalence,and the global stabilization of minimum-phase nonlinear systems显示文摘 | BYRNES C I ISIDORI A WILLEMS J C | 1991 | IEEE Trans on Automatic Control1991，36，11： | 1 |
| 16 | Knowledge sharing in public sector organizations:the effect of organizational characteristics on inter-departmental knowledge sharing显示文摘 | WILLEM A BUELENS M | | 0，，14： | 1 |
| 17 | Renal Sympathetic Denervation as an Adjunct to Catheter Ablation for the Treatment of Ventricular Electrical Storm in the Settins of Acute Mvocardial Infarction显示文摘 | Hoffmann B A Steven D Willems S | 2013 | Journal of cardiovascular electrophysiology2013，24，10： | 1 |
| 18 | The phylogeny of the genus Clostridium: proposal of five new genera and eleven new species eombinations显示文摘 | COLLINS M D LAWSON P A WILLEMS A | 1994 | Int J Syst Baeteriol1994，44，4： | 1 |
| 19 | Classification of 6-dim Nilporent Lie Algebras over Fields of Characteristic Not 2 显示文摘 | WILLEM A | 2007 | Journal of Algebra2007，309，： | 1 |
| 20 | Severe pulmonary embolism: pulmonary artery clot load scores and cardiovascular parameters as pre- dictors of mortality 显示文摘 | Ghaye B Ghuyson A Willems V | 2006 | Radiology2006，239，5： | 1 |
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