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| 1 | High-resolution pseudo-inverse ghost imaging显示文摘We present a pseudo-inverse ghost imaging(PGI) technique which can dramatically enhance the spatial transverse resolution of pseudo-thermal ghost imaging(GI). In comparison with conventional GI, PGI can break the limitation on the imaging resolution imposed by the speckle’s transverse size on the object plane and also enables the reconstruction of an N-pixel image from much less than N measurements. This feature also allows high-resolution imaging of gray-scale objects. Experimental and numerical data assessing the performance of the technique are presented. | Wenlin Gong | 2015 | Photonics Research2015，3，5： | 24 |
| 2 | Ghost imaging for an axially moving target with an unknown constant speed显示文摘The influence of the axial relative motion between the target and the source on ghost imaging(GI) is investigated.Both the analytical and experimental results show that the transverse resolution of GI is reduced as the deviation of the target’s center position from the optical axis or the axial motion range increases. To overcome the motion blur,we propose a deblurring method based on speckle-resizing and speed retrieval, and we experimentally validate its effectiveness for an axially moving target with an unknown constant speed. The results demonstrated here will be very useful to forward-looking GI remote sensing. | Xiaohui Li Chenjin Deng Mingliang Chen Wenlin Gong Shensheng Han | 2015 | Photonics Research2015，3，4： | 15 |
| 3 | Performance analysis of ghost imaging lidar in background light environment显示文摘The effect of background light on the imaging quality of three typical ghost imaging(GI) lidar systems(namely narrow pulsed GI lidar, heterodyne GI lidar, and pulse-compression GI lidar via coherent detection) is investigated. By computing the signal-to-noise ratio(SNR) of fluctuation-correlation GI, our analytical results, which are backed up by numerical simulations, demonstrate that pulse-compression GI lidar via coherent detection has the strongest capacity against background light, whereas the reconstruction quality of narrow pulsed GI lidar is the most vulnerable to background light. The relationship between the peak SNR of the reconstruction image andσ(namely, the signal power to background power ratio) for the three GI lidar systems is also presented, and theresults accord with the curve of SNR-σ. | CHENJIN DENG LONG PAN CHENGLONG WANG XIN GAO WENLIN GONG SHENSHENG HAN | 2017 | Photonics Research2017，5，5： | 13 |
| 4 | Far-field super-resolution ghost imaging with a deep neural network constraint显示文摘Ghost imaging(GI)facilitates image acquisition under low-light conditions by single-pixel measurements and thus has great potential in applications in various fields ranging from biomedical imaging to remote sensing.However,GI usually requires a large amount of single-pixel samplings in order to reconstruct a high-resolution image,imposing a practical limit for its applications.Here we propose a far-field super-resolution GI technique that incorporates the physical model for GI image formation into a deep neural network.The resulting hybrid neural network does not need to pre-train on any dataset,and allows the reconstruction of a far-field image with the resolution beyond the diffraction limit.Furthermore,the physical model imposes a constraint to the network output,making it effectively interpretable.We experimentally demonstrate the proposed GI technique by imaging a flying drone,and show that it outperforms some other widespread GI techniques in terms of both spatial resolution and sampling ratio.We believe that this study provides a new framework for GI,and paves a way for its practical applications. | Fei Wang Chenglong Wang Mingliang Chen Wenlin Gong Yu Zhang Shensheng Han Guohai Situ | 2022 | Light(Science & Applications)2022，11，1： | 6 |
| 5 | Scalar-matrix-structured ghost imaging显示文摘The features of the characteristic matrix used in linear intensity correlation reconstruction methods are directly related to the quality of ghost imaging. In order to suppress the noise caused by the off-diagonal elements in the characteristic matrix, we propose a reconstruction method for ghost imaging called scalar-matrix-structured ghost imaging(SMGI). The characteristic matrix is made to approximate a scalar matrix by modifying the measurement matrix. Experimental results show that SMGI improves the peak signal-to-noise ratio of the object reconstruction significantly compared with differential ghost imaging, even in the case of a nonzero two-arm longitudinal difference, which is a promising result for practical applications. | Chao Yang Chenglong Wang Jian Guan Chi Zhang Shuxu Guo Wenlin Gong Fengli Gao | 2016 | Photonics Research2016，4，6： | 4 |
| 6 | Vascular endothelial growth factor induces multidrug resistance-associated protein 1 overexpression through phosphatidylinositol-3-kinase/protein kinase B signaling pathway and transcription factor specificity protein 1 in BGC823 cell line显示文摘Multidrug 抵抗(MDR ) 是化疗失败和癌复发的最重要的原因之一。但是 rolesof 在 MDR 遗体的联系 MDR 的蛋白质 MRP1 糟糕理解。脉管的 endothelial 生长因素(VEGF ) , themost 之一活跃、特定的脉管的生长因素,在增长,区别,和 metastasisof 癌症起一个重要作用。在 MRP1 的表示上探索 VEGF 的效果,我们使用了 recombinant 人 VEGF 刺激 K562 andBGC-823 房间线。量的即时聚合酶链反应和西方的污点分析证明在 mRNA 和蛋白质层次的 expressionof MRP1 被增加。3-(4,5-Dimethylthiazol-2-yl )-2,5-diphenyl tetrazolium 溴化物 resultsalso 证明 VEGF 显著地提高了与 adriamycin 对待的房间的 IC 50 。探索内在的规章的机制,我们构造了 MRP1 倡导者和 theluciferase 记者基因 recombinant 向量。,酶记者基因试金证明 MRP1 倡导者的活动被 VEGF 刺激显著地增加 LY294002, phosphatidylinositol-3-kinase (PI3K ) 的一个禁止者表明小径的 /proteinkinase B (Akt ) ,减少了这效果。抄写因素特性蛋白质 1 (SP1 ) 有约束力的地点 mutationpartially 由 VEGF 堵住了 MRP1 倡导者活动的起来规定。在摘要,我们的结果表明了 MRP1 的那 VEGF enhancedthe 表情,并且表明小径和 SP1 的 PI3K/Akt 可以涉及这调整。 | Juan Li Xiaojun Wu Jinling Gong Jing Yang Jiayan Leng Qiaoyun Chen Wenlin Xu | 2013 | Acta Biochimica et Biophysica Sinica2013，45，8： | 2 |
| 7 | A FAST CONVERGING SPARSE RECONSTRUCTION ALGORITHM IN GHOST IMAGING显示文摘A fast converging sparse reconstruction algorithm in ghost imaging is presented. It utilizes total variation regularization and its formulation is based on the Karush-Kuhn-Tucker (KKT) theorem in the theory of convex optimization. Tests using experimental data show that, compared with the algorithm of Gradient Projection for Sparse Reconstruction (GPSR), the proposed algorithm yields better results with less computation work. | Li Enrong Chen Mingliang Gong Wenlin Wang Hui Han Shensheng | 2012 | Journal of Electronics(China)2012，29，6： | 2 |
| 8 | Phase-retrieval ghost imaging of complex-valued objects显示文摘 | Gong Wenlin Han Shensheng | 2010 | Physi- cal Review A2010，82，02： | 1 |
| 9 | Analysis of the selectivity filter of the voltage-gated sodium channel NavRh显示文摘NaChBac 是细菌的电压门钠(Na 显示出顺序类似到电压门钙隧道的 v ) 隧道。理解 Na v 隧道,我们联合了调查 Na v Rh,海洋的细菌的 NaChBac ortholog。二个 Na + 绑定地点在我们的模拟在选择过滤器(SF ) 被识别:首先,途径地点 1 由方面组成了的细胞外的 Na + 离子 Ser181 和 Glu183 组织,然后自发地到达精力充沛地 2 由 Leu179 和 Thr178 的羰基氧形成了的更有利的地点。相反, Ca 2+ 离子对被 Glu183 在地点 1 点套住敏感,它然后堵住 Na + 和 Ca 2+ 的入口到 SF 的门厅。另外, Na + 以一种不均匀的方式通过选择过滤器渗入,类似于哺乳动物的 Na v orthologs。这里报导的学习在哺乳动物的 Na 2+ 上在 Na + 上提供卓见进离子选择的机制 > v 隧道。 | Xu Zhang Mengdie Xia Yang Li Huihui Liu Xin Jiang Wenlin Ren Jianping Wu Paul DeCaen Feng Yu Sheng Huang Jianhua He David E Clapham Nieng Yan Haipeng Gong | 2013 | Cell Research2013，23，3： | 1 |
| 10 | Lens ghost imaging with thermal light: from the far field to the near field 显示文摘 | Wenlin Gong Shensheng Han | 2010 | Phys Lett A2010，374，36： | 1 |
| 11 | Correlated imaging in scattering media 显示文摘 | Wenlin Gong Shensheng Han | 2011 | Opt Lett2011，36，3： | 1 |
| 12 | Improving Resolution by the Second-order Correlation of Light Fields显示文摘 | ZHANG Pengli GONG Wenlin Shen Xia | 2009 | Opt Lett2009，34，： | 1 |
| 13 | Correlated Imaging in Scattering Media 显示文摘 | Wenlin Gong Shensheng Han | 2011 | Optics Letters2011，36，： | 1 |
| 14 | Gravitational wave astronomy: the current status显示文摘In the centenary year of Einstein's General Theory of Relativity, this paper reviews the current status of gravitational wave astronomy across a spectrum which stretches from attohertz to kilohertz frequencies. Sect. 1 of this paper reviews the historical development of gravitational wave astronomy from Einstein's first prediction to our current understanding the spectrum. It is shown that detection of signals in the audio frequency spectrum can be expected very soon, and that a north-south pair of next generation detectors would provide large scientific benefits. Sect. 2 reviews the theory of gravitational waves and the principles of detection using laser interferometry. The state of the art Advanced LIGO detectors are then described. These detectors have a high chance of detecting the first events in the near future. Sect. 3 reviews the KAGRA detector currently under development in Japan,which will be the first laser interferometer detector to use cryogenic test masses. Sect. 4 of this paper reviews gravitational wave detection in the nanohertz frequency band using the technique of pulsar timing. Sect. 5 reviews the status of gravitational wave detection in the attohertz frequency band, detectable in the polarisation of the cosmic microwave background, and discusses the prospects for detection of primordial waves from the big bang. The techniques described in sects. 1–5 have already placed significant limits on the strength of gravitational wave sources. Sects. 6 and 7 review ambitious plans for future space based gravitational wave detectors in the millihertz frequency band. Sect. 6 presents a roadmap for development of space based gravitational wave detectors by China while sect. 7 discusses a key enabling technology for space interferometry known as time delay interferometry. | BLAIR David JU Li ZHAO ChunNong WEN LinQing CHU Qi FANG Qi CAI RongGen GAO JiangRui LIN XueChun LIU Dong WU Ling-An ZHU ZongHong REITZE David H. ARAI Koji ZHANG Fan FLAMINIO Raffaele ZHU XingJiang HOBBS George MANCHESTER Richard N. SHANNON Ryan M. BACCIGALUPI Carlo GAO Wei XU Peng BIAN Xing CAO ZhouJian CHANG ZiJing DONG Peng GONG XueFei HUANG ShuangLin JU Peng LUO ZiRen QIANG Li'E TANG WenLin WAN XiaoYun WANG Yue XU ShengNian ZANG YunLong ZHANG HaiPeng LAU Yun-Kau NI Wei-Tou | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，12： | 1 |
| 15 | Correlated imaging in scattering media显示文摘 | Wenlin Gong Shensheng Han | 2011 | Opt Lett2011，36，3： | 1 |
| 16 | A method to improve the visibility of ghost images obtained by thermal light显示文摘 | Wenlin Gong Shensheng Han | 2010 | Phys Lett A2010，374，8： | 1 |
| 17 | The influence of sparsity property of images on ghost imaging with thermal light显示文摘 | Jin Du Wenlin Gong Shensheng Hart | 2012 | Opt Lett2012，37，6： | 1 |
| 18 | Experimental investigation of the quality of lensless super-resolution ghost imaging via sparsity constraints显示文摘 | Wenlin Gong Shensheng Han | 2012 | Phys Lett A2012，376，17： | 1 |
| 19 | Generation of in situ CRISPR-mediated primary and metastatic cancer from monkey liver显示文摘Non-human primates(NHPs)represent the most valuable animals for drug discovery.However,the current main challenge remains that the NHP has not yet been used to develop an efficient translational medicine platform simulating human diseases,such as cancer.This study gen erated an in situ gen e-editi ng approach to in duce efficie nt loss-of-function mutations of Pten and p53 genes for rapid modeling primary and metastatic liver tumors using the CRISPR/Cas9 in the adult cyno molgus mon key.Un der ultraso und guida nee,the CRISPR/Cas9 was injected into the cyno molgus mon key liver through the in trahepatic portal vein.The results showed that the ultraso un d-guided CRISPR/Cas9 resulted in in dels of the Pten and p53 genes in seve n out of eight monkeys.The best mutation efficiencies for Pten and p53 were up to 74.71%and 74.68%,respectively.Furthermore,the morbidity of primary and exte nsively metastatic(lung,splee n,lymph nodes)hepatoma in CRISPR-treated mon keys was 87.5%.The ultraso un d-guided CRISPR system could have great potential to successfully pursue the desired target genes,thereby reducing possible side effects associated with hitting no n-specific off-target genes,and sign ifica ntly in creasing more efficie ncy as well as higher specificity of in situ gene editi ng in vivo,which holds promise as a powerful,yet feasible tool,to edit disease genes to build corresp on ding huma n disease models in adult NHPs and to greatly accelerate the discovery of new drugs and save economic costs. | Liping Zhong Yong Huang Jian He Nuo Yang Banghao Xu Yun Ma Junjie Liu Chao Tang Chengpiao Luo Pan Wu Zongqiang Lai Yu Huo Tao Lu Dongni Huang Wenlin Gong Lu Gan Yiqun Luo Zhikun Zhang Xiyu Liu Yongxiang Zhao | 2022 | Signal Transduction and Targeted Therapy2022，7，1： | 0 |
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