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| 1 | Characteristics of dissolved organic matter(DOM) in leachate with different landfill ages显示文摘学习的主要目的是调查溶解有机物(DOM ) 的特征在沥滤通过化学、分光镜、元素的分析与不同垃圾堆年龄吃了。胡敏酸(哈) , fulvic (FA ) ,并且吸水(HyI ) 部分被与阳离子交换尸方法相结合的 XAD-8 树脂孤立并且净化。荧光刺激排放矩阵光谱学(EEM ) 的分析结果表明荧光山峰是为年轻垃圾堆的像蛋白质的荧光沥滤当为中等、旧的垃圾堆的荧光山峰沥滤时,吃了吃分别地是象腐殖一样和象 fulvic 一样荧光。元素的分析证明那碳,氢,和氮内容与垃圾堆年龄减少了,当氧内容增加了时。而且,在这些孤立的部分的氮内容列在后面:哈 >
HyI >
FA。元素的分析,英尺红外,和荧光 EEM 的结果也证实脂肪族的功能的组的芳香的碳和部分更充满沥滤与增加垃圾堆年龄吃了样品。 | HUO Shouliang XI Beidou YU Haichan HE Liansheng FAN Shilei LIU Hongliang | 2008 | Journal of Environmental Sciences2008，20，4： | 52 |
| 2 | Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020显示文摘African swine fever virus(ASFV)has been circulating in China for more than two years,and it is not clear whether the biological properties of the virus have changed.Here,we report on our surveillance of ASFVs in seven provinces of China,from June to December,2020.A total of 22 viruses were isolated and characterized as genotype II ASFVs,with mutations,deletions,insertions,or short-fragment replacement occurring in all isolates compared with Pig/HLJ/2018(HLJ/18),the earliest isolate in China.Eleven isolates had four different types of natural mutations or deletion in the EP402R gene and displayed a nonhemadsorbing(non-HAD)phenotype.Four isolates were tested for virulence in pigs;two were found to be as highly lethal as HLJ/18.However,two non-HAD isolates showed lower virulence but were highly transmissible;infection with 106 TCID50 dose was partially lethal and caused acute or sub-acute disease,whereas 103 TCID50 dose caused non-lethal,sub-acute or chronic disease,and persistent infection.The emergence of lower virulent natural mutants brings greater difficulty to the early diagnosis of ASF and creates new challenges for ASFV control. | Encheng Sun Zhenjiang Zhang Zilong Wang Xijun He Xianfeng Zhang Lulu Wang Wenqing Wang Lianyu Huang Fei Xi Haoyue Huangfu Ghebremedhin Tsegay Hong Huo Jianhong Sun Zhijun Tian Wei Xia Xuewu Yu Fang Li Renqiang Liu Yuntao Guan Dongming Zhao Zhigao Bu | 2021 | Science China(Life Sciences)2021，64，5： | 46 |
| 3 | Anti-Helicobacter pylori therapy followed by celecoxib on progression of gastric precancerous lesions显示文摘AIM:To evaluate whether celecoxib,a selective cyclooxygenase 2(COX-2) inhibitor,could reduce the severity of gastric precancerous lesions following Helicobacter pylori(H pylori) eradication.METHODS:H pylori-eradicated patients with gastric precancerous lesions randomly received either celecoxib(n=30) or placebo(n=30) for up to 3 mo.COX-2 expression and activity was determined by immunostaining and prostaglandin E2(PGE2) assay,cell proliferation by Ki-67 immunostaining,apoptosis by TUNEL staining and angiogenesis by microvascular density(MVD) assay using CD31 staining.RESULTS:COX-2 protein expression was significantly increased in gastric precancerous lesions(atrophy,intestinal metaplasia and dysplasia,respectively) compared with chronic gastritis,and was concomitant with an increase in cell proliferation and angiogenesis.A significant improvement in precancerous lesions was observed in patients who received celecoxib compared with those who received placebo(P<0.001).Of these three changes,84.6% of sites with dysplasia regressed in patients treated with celecoxib(P=0.002) compared with 60% in the placebo group,suggesting that celecoxib was effective on the regression of dysplasia.COX-2 protein expression(P<0.001) and COX-2 activity(P<0.001) in the gastric tissues were consistently lower in celecoxib-treated patients compared with the placebo-treated subjects.Moreover,it was also shown that celecoxib suppressed cell proliferation(P<0.01),induced cell apoptosis(P<0.01) and inhibited angiogenesis with decreased MVD(P<0.001).However,all of these effects were not seen in placebo-treated subjects.Furthermore,COX-2 inhibition resulted in the up-regulation of PPARγ expression,a protective molecule with anti-neoplastic effects.CONCLUSION:H pylori eradication therapy followed by celecoxib treatment improves gastric precancerous lesions by inhibiting COX-2 activity,inducing apoptosis,and suppressing cell proliferation and angiogenesis. | Li-Jing Zhang Shi-Yan Wang Xiao-Hui Huo Zhen-Long Zhu Jian-Kun Chu Jin-Cheng Ma Dong-Sheng Cui Ping Gu Zeng-Ren Zhao Ming-Wei Wang Jun Yu | 2009 | World Journal of Gastroenterology2009，15，22： | 32 |
| 4 | Chinese Multidisciplinary Expert Consensus on the Diagnosis and Treatment of Hyperuricemia and Related Diseases显示文摘 | Zou, He-Jian Wu, Hu-Sheng Zhou, Jing-Guo Zeng, Xue-Jun Dai, Lie Wu, Hua-Xiang Zhu, Xiao-Xia Mei, Chang-Lin Hao, Chuan-Ming Chen, Nan Liu, Bi-Cheng Chen, Jiang-Hua Yang, Li Nie, Jing Yu, Chen Peng, Ai Yu, Sheng-Qiang Li, Lin Ge, Jun-Bo Huo, Yong Zhang, Shu-Yang Chen, Yun-Dai Dong, Yu-Gang Liang, Chun Dai, Yu-Xiang Gao, Xin Li, Chang-Gui Zhao, Jia-Jun Chen, Hai-Bing Cheng, Zhi-Feng Lin, Huan-Dong Guan, Yang-Tai Wang, Kai Luo, Ben-Yan Dai, Ruo-Lian Jiang, Quan Xue, Luan Liang, Chao-Chao Chen, Ming Fan, Song | 2017 | Chinese Medical Journal2017，，20： | 30 |
| 5 | One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs显示文摘CRISPR/Cas9 系统是一个有效编辑基因的方法,但是编辑基因的动物的多数显示出 mosaicism,与编辑仅仅在房间的部分发生。这里,我们证明那单个基因或多重基因能被 Cas9 mRNA 和多重邻近的单个指南的 RNA 的 zygotic 注射完全在老鼠和猴子胚胎击倒(spaced 10-200 bp 分开) 指向仅仅一把单个钥匙每基因的 exon。个别地在 Y 染色体上跟随八基因的指向的删除的 F0 老鼠的 Phenotypic 分析在产生猛烈老鼠表明了这条途径的坚韧性。重要地,这条途径在高效率交付完全的基因大美人(Arntl 上的 100% 并且 91% 在 Prrt2 上) 在猴子胚胎。最后,我们能在一个单个步骤产生一只完全的 Prrt2 猛烈猴子,表明在很快建立编辑基因的猴子模型的这条途径的实用性。 | Erwei Zuo Yi-Jun Cai Kui Li Yu Wei Bang-An Wang Yidi Sun Zhen Liu Jiwei Liu Xinde Hu Wei Wei Xiaona Huo Linyu Shi Cheng Tang Dan Liang Yan Wang Yan-Hong Nie Chen-Chen Zhang Xuan Yao Xing Wang Changyang Zhou Wenqin Ying Qifang Wang Ren-Chao Chen Qi Shen Guo-Liang Xu Jinsong Li Qiang Sun Zhi-Qi Xiong Hui Yang | 2017 | Cell Research2017，27，7： | 21 |
| 6 | Ulva prolifera green-tide outbreaks and their environmental impact in the Yellow Sea, China显示文摘The Ulva prolifera green tides in the Yellow Sea, China, which have been occurring since 2007, are a serious environmental problem attracting worldwide attention. Despite extensive research, the outbreak mechanisms have not been fully understood. Comprehensive analysis of anthropogenic and natural biotic and abiotic factors reveals that human activities, regional physicochemical conditions and algal physiological characteristics as well as ocean warming and biological interactions(with microorganism or other macroalgae) are closely related to the occurrence of green tides. Dynamics of these factors and their interactions could explain why green tides suddenly occurred in 2007 and decreased abruptly in 2017.Moreover, the consequence of green tides is serious. The decay of macroalgal biomass could result in hypoxia and acidification, possibly induce red tide and even have a long-lasting impact on coastal carbon cycles and the ecosystem. Accordingly, corresponding countermeasures have been proposed in our study for future reference in ecosystem management strategies and sustainable development policy. | Yongyu Zhang Peimin He Hongmei Li Gang Li Jihua Liu Fanglue Jiao Jianheng Zhang Yuanzi Huo Xiaoyong Shi Rongguo Su Naihao Ye Dongyan Liu Rencheng Yu Zongling Wang Mingjiang Zhou Nianzhi Jiao | 2019 | National Science Review2019，6，4： | 17 |
| 7 | Cardioprotective effects of Guanxinshutong (GXST) against myocardial ischemia/ reperfusion injury in rats显示文摘对 cardioprotective 药的灌注损害的 BackgroundThe 保护的效果最近被评估了并且发现了不适当。Guanxinshutong (GXST ) ,传统的植物的联合和蒙古的药,在在临床的试用对待心绞痛有效、安全。我们在老鼠对心肌的局部缺血和灌注(MI/R ) 损害估计 GXST 的 cardioprotective 效果并且探索它的可能的 mechanism.MethodsForty -- 五只男 Sprague Dawley 老鼠被使随机化进三个组:non-MI/R 组(假冒, n = 15 ) ,与车辆对待的 MI/R 组(控制, n = 15 ) 并且与 GXST 对待的 MI/R 组(药, n = 15 ) 。MI/R 被左前面的下降冠的动脉(男孩) 的结扎导致 30 分钟,在控制和药组由 2/24 小时灌注列在后面。在假冒的组,没有吸藏, LAD 被暴露。GXST 粉末(在药组) 或盐(在控制和假冒的组) 在外科以前从 7 白天经由直接胃的 gavage 被管理。血样品从颈动脉动脉被收集(10 只老鼠各组织) 在 2 小时灌注以后,决定肿瘤坏死 factor-α 的层次;(TNF-α) , interleukin-1β(IL-1β) , interleukin-6 (IL-6 ) 和用连接酶的 immunosorbent 试金的细胞间的粘附 molecule-1 (ICAM-1 ) 。动物然后被牺牲,心为组织病理学说和西方的污点分析被收获。梗塞尺寸在留下被测量在在 24 小时 reperfusion.ResultsGXST 以后的每个组的五只老鼠显著地减少了 TNF-α 的层次;, IL-1β, IL-6, ICAM-1, apoptosis 索引(AI ) 和梗塞缩放。GXST 显然也禁止了原子因素 kappa B (NF-κ B ) 活动什么时候与控制组相比(所有 P <0.05 ).ConclusionsGXST 在在老鼠保护心肌层免于 MI/R 损害是有效的。它的可能的 cardioprotective 机制包含煽动性的反应和 apoptosis 追随者 MI/R 损害的抑制。 | Zhuo Llang Li-Feng Llu Tian-Ming Yao Yu Huo Ya-Ling Han | 2012 | Journal of Geriatric Cardiology2012，9，2： | 13 |
| 8 | A versatile cooperative template-directed coating method to synthesize hollow and yolk-shell mesoporous zirconium titanium oxide nanospheres as catalytic reactors显示文摘 | Buyuan Guan Tao Wang Shangjing Zeng Xue Wang Dong An Dongmei Wang Yu Cao Dingxuan Ma Yunling Liu Qisheng Huo | 2014 | Nano Research2014，7，2： | 12 |
| 9 | Effects of bamboo vinegar powder on growth performance and mRNA expression levels of interleukin-10,interleukin-22,and interleukin-25 in immune organs of weaned piglets显示文摘The aim of this study was to explore the effects of bamboo vinegar powder on growth performance,diarrhea situation and mRNA expression levels of cytokines i.e., interleukin-10(IL-10), interleukin-22(IL-22), and interleukin-25(IL-25) in immune organs of weaned piglets, and to accumulate theoretical data for the application of bamboo vinegar powder in weaned piglet production. Forty-five crossbred(Duroc × Landrace × Yorkshire, all male) weaned piglets with similar body weight(6.74 ± 0.17 kg) at 31 days of age were randomly assigned to 5 treatments with 3 replicates per treatment and 3 piglets in each replicate. The five treatments were as follows: CON(a basal diet), ANT(the basal diet + 0.12% antibiotics),BV1(the basal diet + 0.1% bamboo vinegar powder), BV5(the basal diet + 0.5% bamboo vinegar powder),BV10(the basal diet + 1.0% bamboo vinegar powder). This experiment lasted 35 days. The growth performance and diarrhea situation were recorded. The relative mRNA expression levels of IL-10, IL-22 and IL-25 in liver, spleen, duodenum and mesenteric lymph nodes were detected by real-time PCR. Feed:gain of BV5 was significantly lower than that of CON(P < 0.05). In comparison with CON, diarrhea rate and diarrhea index of BV1 and BV5 all tended to decrease(P < 0.1). Compared with CON, mRNA expression level of IL-10 in liver of ANT tended to be lower(P < 0.1) and these of BV1, BV5 and BV10 were significantly reduced(P < 0.05). The mRNA expression levels of IL-10 in duodenum of ANT, BV1, BV5 and BV10 were all lower than those of CON, of which BV10 had significantly decreased IL-10 mRNA expression in duodenum(P < 0.05). The mRNA expression levels of IL-22 in duodenum of ANT, BV1, BV5 and BV10 all tended to be inhibited compared with CON(P < 0.1). With the increase of bamboo vinegar powder dosage, mRNA expression levels of IL-25 in spleen and mesenteric lymph nodes of BV1, BV5 and BV10 tended to be up-regulated. Overall, bamboo vinegar powder could improve growth performance,and regulate mRNA expression levels of IL-10, IL-22 and IL-25 in immune organs of weaned piglets. The dosage at 0.5% showed optimum effects. | Yongjiu Huo Zhengxu Liu Han Xuan Chunbin Lu Lihuai Yu Wenbin Bao Guoqi Zhao | 2016 | Animal Nutrition2016，，2： | 11 |
| 10 | Economic burden and its associated factors of hospitalized patients infected with A (H7N9) virus: a retrospective study in Eastern China, 2013–2014显示文摘Background:H7N9 continues to cause human infections and remains a pandemic concern.Understanding the economic impacts of this novel disease is important for making decisions on health resource allocation,including infectious disease prevention and control investment.However,there are limited data on such impacts.Methods:Hospitalized laboratory-confirmed H7N9 patients or their families in Jiangsu Province of China were interviewed.Patients’direct medical costs of hospitalization were derived from their hospital bills.A generalized linear model was employed to estimate the mean direct medical costs of patients with different characteristics.Results:The mean direct cost of hospitalization for H7N9 was estimated to be¥71060(95%CI,48180–104820),i.e.,US$10996(95%CI,7455–16220),and was¥12060(US$1861),¥136120(US$21001)and¥218610(US$33728)for those who had mild or severe symptoms or who died,respectively.The principal components of the total fees differed among patients with different disease severity,although medication fees were always the largest contributors.Disease severity,proportion of reimbursement and family member monthly average income were identified as the key factors that contributed to a patient’s direct medical cost of hospitalization.Conclusions:The direct medical costs of hospitalized patients with H7N9 are significant,and far surpass the annual per capita income of Jiangsu Province,China.The influencing factors identified should be taken into account when developing related health insurance policies and making health resource allocation.Trial registration:Not applicable.This is a survey study with no health care intervention implemented on human participants. | Xiang Huo Li-Ling Chen Lei Hong Lun-Hui Xiang Fen-Yang Tang Shan-Hui Chen Qiang Gao Cong Chen Qi-gang Dai Chuan-Wu Sun Ke Xu Wen-Jun Dai Xian Qi Chang-Cheng Li Hui-Yan Yu Yin Zhou Hao-Di Huang Xing-Yang Pan Chang-sha Xu Ming-Hao Zhou Chang-Jun Bao | 2016 | Infectious Diseases of Poverty2016，5，1： | 10 |
| 11 | Chinese expert consensus on the non-invasive imaging examination pathways of stable coronary artery disease显示文摘 | Yun-Dai CHEN Wei-Yi FANG Ji-Yan CHEN Zhan-Ming FAN Chuan-Yu GAO Jun-Bo GE Zuo-Xiang HE Yong HUO Lang LI Si-Jin LI Xi-Lie LU Bin LV Ju-Ying QIAN Ya-Jun SHI Zhu-Jun SHEN Jing WANG Yi-Ning WANG Lei XU Li YANG Bo YU Mei ZHANG Jun-Jie YANG Shu-Yang ZHANG Xiao-Li ZHANG Shi-Hua ZHAO Yang ZHENG Yu-Chi HAN Guang ZHI | 2018 | Journal of Geriatric Cardiology2018，15，1： | 10 |
| 12 | Monitoring of 943 organic micropollutants in wastewater from municipal wastewater treatment plants with secondary and advanced treatment processes显示文摘To perform a systematic survey on the occurrence and removal of micropollutants during municipal wastewater treatment, 943 semi-volatile organic chemicals in 32 wastewater samples including influents of secondary treatments, secondary effluents and final effluents(effluents of advanced treatments), which were collected from seven full-scale municipal wastewater treatment plants(MWTPs) in China, were examined by gas chromatography-mass spectrometry(GC-MS) coupled with an automated identification and quantification system with a database(AIQS-DB). In total, 196 and 145 chemicals were detected in secondary and final effluents, respectively. The majority of the total concentrations(average removal efficiency, 87.0%±5.9%) of the micropollutants were removed during secondary treatments. However, advanced treatments achieved different micropollutant removal extents from secondary effluents depending on the different treatment processes employed. Highly variable removal efficiencies of total concentrations(32.7%–99.3%) were observed among the different advanced processes. Among them,ozonation-based processes could remove 70.0%–80.9% of the total concentrations of studied micropollutants. The potentially harmful micropollutants, based on their detection frequency and concentration in secondary and final effluents, were polycyclic aromatic hydrocarbons(PAHs)(2-methylnaphthalene, fluoranthene, pyrene, naphthalene and phenanthrene), phosphorus flame retardants(tributyl phosphate(TBP), tris(2-chloroethyl)phosphate(TCEP) and tris(1,3-dichloro-2-propyl) phosphate(TDCP)), phthalates(bis(2-ethylhexyl)phthalate(DEHP)), benzothiazoles(benzothiazole,2-(methylthio)-benzothiazol, and 2(3H)-benzothiazolone) and phenol. This study indicated that the presence of considerable amounts of micropollutants in secondary effluent creates the need for suitable advanced treatment before their reuse. | Juan Wang Zhe Tian Yingbin Huo Min Yang Xingcan Zheng Yu Zhang | 2018 | Journal of Environmental Sciences2018，30，5： | 9 |
| 13 | Assessment of the sources and transformations of nitrogen in a plain river network region using a stable isotope approach显示文摘The great spatial and temporal variability in hydrological conditions and nitrogen(N)processing introduces large uncertainties to the identification of N sources and quantifying N cycles in plain river network regions. By combining isotopic data with chemical and hydrologic measurements, we determined the relative importance of N sources and biogeochemical N processes in the Taige River in the East Plain Region of China. The river was polluted more seriously by anthropogenic inputs in winter than in summer. Manure and urban sewage effluent were the main nitrate(NO-3) sources, with the nitrification of N-containing organic materials serving as another important source of NO-3. In the downstream, with minor variations in hydrological conditions, nitrification played a more important role than assimilation for the decreasing ammonium(NH+4-N) concentrations.The N isotopic enrichment factors(ε) during NH+4utilization ranged from- 13.88‰ in March to- 29.00‰ in July. The ratio of the increase in δ18O and δ15N of river NO-3in the downstream was 1.04 in January and 0.92 in March. This ratio indicated that NO-3assimilation by phytoplankton was responsible for the increasing δ15N and δ18O values of NO-3in winter. The relationships between δ15N of particulate organic nitrogen and isotopic compositions of dissolved inorganic nitrogen indicated that the phytoplankton in the Taige River probably utilized NH+4preferentially and mainly in summer, while in winter, NO-3assimilation by phytoplankton was dominant. | Jingtao Ding Beidou Xi Qigong Xu Jing Su Shouliang Huo Hongliang Liu Yijun Yu Yanbo Zhang | 2015 | Journal of Environmental Sciences2015，27，4： | 9 |
| 14 | Quality Control and Nonclinical Research on CAR-T Cell Products: General Principles and Key Issues显示文摘Adoptive cell therapy using chimeric antigen receptor T (CAR-T) cells, which is a promising cancer immunotherapy strategy, has been developing very rapidly in recent years. CAR-T cells are genetically modified T cells that can specifically recognize tumor specific antigens on the surface of tumor cells, and then effectively kill tumor cells. At present, exciting results are being achieved in clinical applications of CAR-T cells for patients with hematological malignancies. The research and development of CAR-T cells for various targets and for the treatment of solid tumors have become a hot topic worldwide, so an increasing number of investigational new drug applications (INDAs) and new drug applications (NDAs) of CAR-T cell products are expected to be submitted in future. The quality control and nonclinical research of these products are of great significance in ensuring the safety and effectiveness of these products;however, they also present great challenges and difficulties. This article discusses the general principles of and key issues regarding the quality control and nonclinical research of CAR-T cell products based on their product characteristics and on relevant guidelines for gene and cell therapy products. | Yonghong Li Yan Huo Lei Yu Junzhi Wang | 2019 | Engineering2019，5，1： | 9 |
| 15 | Optical properties of NaY(MoO4)2:Eu3+ nanophosphors prepared by molten salt method显示文摘We synthesized NaY(MoO4)2:Eu3+phosphors of different doping concentrations by a molten salt method.This facile way possesses advantages such as simple process,lower calcination temperature(350℃)and small particle size(70 nm).The crystal system is tetragonal phase and crystal lattice is body centered.The photo luminescence measurements including emission spectra,excitation spectra and fluorescence decay curves were carried out,elucidating that NaY(MoO4)2:Eu3+can be effectively excited by near UV and blue light.Moreover,it can be concluded that Eu3+energy transfer type is exchange interaction.Huang-Rhys factor and the critical energy transfer distance(Rc)were calculated to be 0.043 and 0.995 nm,respectively.Auzel’s model was used to obtain the intrinsic radiative transition lifetime of5 D0 level(τ0=0.923 ms).Furthermore,a calculation method was used to calculate refractive index n of nontransparent NaY(MoO4)2:1 mol%Eu3+phosphor,and n was obtained to be 1.86. | Lin Bai Qingyu Meng Mingxue Huo Yu Sui | 2019 | Journal of Rare Earths2019，37，12： | 8 |
| 16 | Multiple-Element Matching Reservoir Formation and Quantitative Prediction of Favorable Areas in Superimposed Basins显示文摘在韦斯特中国的附加的盆经历了多级式的构造事件和 multicycle 烃水库形成,并且复杂的烃水库在这种类型的盆广泛地被发现了。大多数复杂的烃水库被重定位,规模重建,部件变化和阶段国家转变描绘,并且他们的分布是很困难的预言。研究显示出那地区性的 caprock (C) ,高质量的沉积外形(存款, D ) , paleohighs (山, M ) 并且来源岩石(S) 是贡献复杂的烃水库形成和西方的附加的盆的分发的四个地质的元素。四个元素的纵的顺序的联合控制烃水库形成的阶层,并且平面重迭和联合控制烃水库的范围,他们在 geohistory 的同时的联合效果决定烃水库形成的时间。多重元素的匹配水库形成介绍水库形成的一个基本模式在里面附加的盆,和我们建议它被表示为 T-CDMS。基于多重元素的匹配水库形成模式,一个全面水库形成索引(Tcdms ) 在这篇论文被开发描绘水库形成条件,和一个方法被介绍在附加的盆预言水库形成范围和出现的概率。通过新理论,方法和技术的申请,在奥陶纪的出现的有利水库形成范围和概率在四个不同水库形成时期在 Tarim 盆指向地区被预言。结果证明中央 Tarim, Yinmaili 和 Lunnan 是奥陶纪油和煤气的地可能形成了的三个很有利的区域。有当前发现的烃水库的预言结果的巧合到达 97% 。这反映新理论,方法和技术的有效性和可靠性。 | WANG Huaijie PANG Xiongqi WANG Zhaoming YU Qiuhua HUO Zhipeng MENG Qingyang | 2010 | Acta Geologica Sinica(English Edition)2010，84，5： | 8 |
| 17 | Effects of Salinity on Embryonic Development, Survival, and Growth of Crassostrea hongkongensis显示文摘This study examined the effects of salinity on embryonic development, survival, and growth of the Hong Kong oyster Crassostrea hongkongensis. The embryos, larvae, and juveniles of C. hongkongensis were held in artificial seawater at three different salinities(low, 15; medium, 23; and high, 30) to determine the optimum hatchery and nursery conditions for mass production of the seeds. Results showed that the percentage production of straight-hinged larvae from fertilized eggs was significantly lower at the high salinity than at the low- and medium-salinities(P < 0.05). The survival rates of larvae and juveniles differed significantly among the three salinity trials, with the highest survival rate observed at the low salinity(P < 0.05). The shell height of larvae was significantly larger at the low salinity than at the high and medium salinities from days 9 to 15(P < 0.05), whereas that of juveniles was significantly larger at the low salinity than at the high and medium salinities on day 70(P < 0.05). These results indicate that the larvae and juveniles of C. hongkongensis are tolerant to a wide range of salinities(15 to 30), but show better growth and survival at relatively low salinities. Thus, it is recommended to use relatively low salinities in hatchery and nursery systems for improved yields of C. hongkongensis. | HUO Zhongming WANG Zhaoping LIANG Jian ZHANG Yuehuan SHEN Jianping YAO Tuo SU Jiaqi YU Ruihai | 2014 | Journal of Ocean University of China2014，13，4： | 6 |
| 18 | Historical records of polycyclic aromatic hydrocarbon deposition in a shallow eutrophic lake:Impacts of sources and sedimentological conditions显示文摘Sediment core samples collected from Lake Chaohu were analyzed for 15 priority polycyclic aromatic hydrocarbons(PAHs)to assess the spatial and temporal distributions of the PAHs during lacustrine sedimentary processes and regional economic development.Assessing the PAH sedimentary records over an approximately 100-year time span,we identified two stages in the PAH inputs and sources(before the 1970 s and after the 1970s)in the eastern lake region near a village,whereas three stages(before the 1950 s,1950s–1990s and after the1990s)were identified in the western lake region near urban and industrial areas.Rapid increases in the PAH depositional fluxes occurred during the second stage due to increased human activities in the Lake Chaohu basin.The composition and isomeric ratios of the PAHs revealed that pyrolysis is the main source of PAHs in this lake.Strong positive relationships between PAH concentration and the total organic carbon concentration,sediment grain size(< 4 μm),as well as the local population and Gross Domestic Product indicated that the sedimentary conditions impact the depositional characteristics of the PAHs;simultaneously,socioeconomic activities,such as energy consumption and the levels of urban industrialization and civilization,affect both the composition and abundance of the PAHs. | Chaocan Li Shouliang Huo Zhiqiang Yu Wei Guo Beidou Xi Zhuoshi He Xiangying Zeng Fengchang Wu | 2016 | Journal of Environmental Sciences2016，28，3： | 6 |
| 19 | Microencapsulated ammonium polyphosphate by polyurethane with segment of dipentaerythritol and its application in flame retardant polypropylene显示文摘Dipentaerythritol(DPER),4,40-diphenylmethanediisocyanate(MDI)and melamine(MEL)are used as raw materials to microencapsulate ammonium polyphosphate(MAPP)in situ polymerization.The MAPP is characterized by Fourier transform infrared(FT-IR),scanning electron microscopy(SEM),transmission electron microscopy(TEM)and thermal gravimetric analysis(TGA).The results show that the coating operation can effectively improve water resistance of ammonium polyphosphate(APP),and MAPP has higher residual rate than that of APP after combustion.The flame retardant action of MAPP and APP in polypropylene(PP)is investigated by the limited oxygen index(LOI),vertical burning test(UL-94),TGA,SEM,and cone calorimeter test(CCT).The LOI value of the PP/MAPP composite at the same loading is higher than that of PP/APP composite.UL 94 ratings of PP/MAPP composites are raised to V-0 at 20 wt%loading.The results of CCT also show that MAPP is more efficient than APP.The morphological structures observed by digital photos and SEM demonstrated that MAPP could be promoted to form the continuous and compact intumescent char layer.The flame retardant mechanism of PP/MAPP is also discussed. | Shouwu Yu Shujuan Xiao Zewen Zhao Xiaowen Huo Junfu Wei | 2019 | Chinese Journal of Chemical Engineering2019，27，7： | 6 |
| 20 | Two Cases of Multi-antibiotic Resistant Cronobacter spp. Infections of Infants in China*显示文摘Infections by Cronobacter spp. are hazardous to infants since they can lead to neonatal meningitis, bacteremia, and necrotizing enterocolitis. Cronobacter spp. are frequently resistant to β-lactam derivatives, macrolides, and aminoglycosides. In addition, multi-resistant strains have also been detected. In China, the isolation rate of Cronobacter spp. from commercial powdered infant formula(PIF) or follow-up formula(FUF) is relatively high. Nevertheless, clinical cases of Cronobacter infection have been ignored to date. Here we describe two cases of Cronobacter infection detected at the Wuhan Women and Children Medical Care Center Hospital(Wuhan City, China). We provide the genomic analysis of the isolates and the antibiotic-resistance profiles of the two strains. The Cronobacter strains identified in this study were not susceptible to third-generation cephalosporins, aminoglycoside, and/or trimethoprim-sulfamethoxazole. Whole genome sequencing revealed various genes known to encode antibiotic resistance. Future studies are needed to determine whether the genes predicted in this study are functional. As with Enterobacter spp., the antibiotic resistance of Cronobacter is a serious issue that requires more attention. | CUI Jing Hua YU Bo XIANG Yun ZHANG Zhen ZHANG Ting ZENG Ying Chun CUI Zhi Gang HUO Xi Xiang | 2017 | Biomedical and Environmental Sciences2017，30，8： | 6 |
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