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| 1 | 静脉血栓栓塞症的抗血栓治疗:美国《胸科学》杂志指南显示文摘包括深静脉血栓和肺栓塞在内的静脉血栓栓塞症是癌症患者的主要并发症,发生率为4%~20%,并且是常见的潜在致命性急症。本文介绍了美国《胸科学》杂志指南中VET的抗血栓治疗的部分内容,其以第9版《美国胸内科医师学会循证临床实践指南》中的《静脉血栓栓塞症的抗血栓治疗:抗血栓治疗和阻止血栓形成》一文为参照,基于静脉血栓栓塞症治疗的Ⅲ期试验的发表年份,对口服抗凝剂(达比加群、利伐沙班、阿哌沙班、依度沙班)进行先后阐述(但是这一排序并不是指南专家组对药剂的优劣排序),以为临床医生提供参考。 | Kearon C Akl EA Ornelas J Blaivas A Jimenez D Bounameaux H Huisman M King CS MorrisT Sood N Stevens SM Vintch JRE Wells P Woller SC Moores CL 本刊编辑部 | 2016 | 中国全科医学2016，19，9： | 10 |
| 2 | 人类组织中未识别的间质结构及其分布显示文摘基于探针的共聚焦激光显微镜(pCLE)是一种体内实时成像技术,通常在静脉注射荧光素后,对深度60~70μm的人体组织进行结构评估。在未知解剖关系的肝外胆管pCLE检查中,充满荧光素的窦隙由20μm宽的黑暗分支带围绕大的多边形空间,呈现网状模式(reticular pattern),冷冻活检证实为黏膜下层的一部分。 | 张仕强 方三高 Benias P C Wells R G Sackey-Aboagye B | 2018 | 临床与实验病理学杂志2018，34，11： | 7 |
| 3 | 叶酸与甲酰四氢叶酸用于减少甲氨蝶呤治疗副作用(摘要)显示文摘1 背景 甲氨蝶呤用于治疗许多风湿病,其短期疗效已被证实。但毒性使不少患者不能从中受益,其中叶酸缺乏可增加其毒性。类风湿关节炎患者常有叶酸缺乏,经甲氨蝶呤治疗后叶酸储备就进一步减少。甲氨蝶呤的胃肠道和血液学副作用都与叶酸缺乏有关,可以预见,叶酸补充疗法将有助改善低剂量甲氨蝶呤治疗的副作用。对此,已有不少试验开展,并提出不同的副作用减少率。 | Ortiz Z SheaB Suarez Almazor M Moher D Wells G Tugwell P 姚如愚 | 2001 | 循证医学2001，1，1： | 4 |
| 4 | Faecalibacterium prausnitzii and human intestinal health显示文摘 | S Miquel R Martín O Rossi LG Bermúdez-Humarán JM Chatel H Sokol M Thomas JM Wells P Langella | 2013 | Current Opinion in Microbiology2013，，： | 3 |
| 5 | Acute colonic pseudo-obstruction: A systematic review of aetiology and mechanisms显示文摘AIM To critically review the literature addressing the definition, epidemiology, aetiology and pathophysiology of acute colonic pseudo-obstruction(ACPO).METHODS A systematic search was performed to identify articles investigating the aetiology and pathophysiology of ACPO. A narrative synthesis of the evidence was undertaken. RESULTS No consistent approach to the definition or reporting of ACPO has been developed, which has led to overlapping investigation with other conditions. A vast array of risk factors has been identified, supporting a multifactorial aetiology. The pathophysiological mechanisms remain unclear, but are likely related to altered autonomic regulation of colonic motility, in the setting of other predisposing factors. CONCLUSION Future research should aim to establish a clear and consistent definition of ACPO, and elucidate the pathophysiological mechanisms leading to altered colonic function. An improved understanding of the aetiology of ACPO may facilitate the development of targeted strategies for its prevention and treatment. | Cameron I Wells Gregory O’Grady Ian P Bissett | 2017 | World Journal of Gastroenterology2017，23，30： | 2 |
| 6 | 显示文摘 | Wells J W Kallehauge J F Hofmann P | 2007 | J Phys:Condens Matter2007，19，17： | 1 |
| 7 | The Determinants of Venture Capital Funding : Evidence Across Countries 显示文摘 | Jengl A Wells P C | 2000 | Journal of Corporate Finance2000，，6： | 1 |
| 8 | Importance of left atrial appendage flow as a predictor of thromboembolic events in patients with atrial fibrillation显示文摘 | Kamp O Verhorst P M J Welling R C | 1999 | Eur Heart J1999，20，13： | 1 |
| 9 | Derivation of a simple clinical model to categorize patients probalfility of pulmonary embolism:increasing the models utility with the SimpliRed D-Dimmer显示文摘 | Wells P S Anderson D R Rodger M | 2000 | Thromb Haemost2000，83，： | 1 |
| 10 | Complexity of the discrete time-cost tradeoff problem for project networks 显示文摘 | De P Dunne E J Ghosh J B Wells C E | 1997 | Operations Research1997，45，2： | 1 |
| 11 | Evaluation of time- temperature related quality changes in icecream during storage 显示文摘 | DOLAN K D SINGH R P WELLS J H | 1985 | Journal of Food Processing and Preservation1985，9，： | 1 |
| 12 | Multi-modal volume registration by maximization of mutual infcrmation显示文摘 | Wells W M Ⅲ Viola P Atsumi H | 1996 | Med Image Anal1996，3，1： | 1 |
| 13 | Optimization of a bath for electroless plating and its use for the produc- tion of nickel - phosphorus - silicon carbide coatings 显示文摘 | Kalantary M R Holbrook K A Wells P B | 1993 | Transaction of Institute of Metal Finishing1993，71，2： | 1 |
| 14 | Large scale production of recombinant human lactoferrin in the milk of transgenic cows 显示文摘 | VAN BERKEL P H WELLING M M GEERTS M | 2002 | Nat Biotechnol2002，20，5： | 1 |
| 15 | Two sesquiterpene furans with new carbocyclic ringsystems and related thiol acetates from a species of thesponge genus Dysidea显示文摘 | KAZLAUSKAS R MURPHY P T WELLS R J | 1978 | Tetrahedron Lett1978，49，： | 1 |
| 16 | Effects of seed dispersal on spatial genetic structure in populations of Rutidosis leptorrhychoides with different levels of correlated paternity显示文摘 | WELLS G P YOUNG A G | 2002 | Genetical Research2002，79，3： | 1 |
| 17 | Surgical management of spinal cord hemangioblastomas in patients with yon Hippel-Lindau disease显示文摘 | Lonser RR Well P J Wznebo JE | 2003 | J Neurosurg2003，98，1： | 1 |
| 18 | Differentialion of the origin of wide QRS complexes by the net amplitude of the QRS in lead V6显示文摘 | Kremers MS Wells P Black W | 1989 | Am J Cardiol1989，64，16： | 1 |
| 19 | Integrated strategies for the diagnosis of venous thromboembolism显示文摘 | Wells P S | 2007 | J Thromb Haemost2007，5，： | 1 |
| 20 | Alignment by maximization of mutual information显示文摘 | P A Viola W M Wells III | 1997 | International Journal of Computer Vision1997，24，2： | 1 |
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