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| 1 | Spatial energy efficiency patterns and the coupling relationship with industrial structure: A study on Liaoning Province, China显示文摘用在辽宁省的 14 个府级的城市的一件样品,这研究首先从下列三个观点探索了空间层次和精力效率的结构的特征:精力技术效率基于数据包封分析,精力消费每 GDP,和精力利用效率联合起来联合以前的二个索引。在在每个城市里测量并且分析工业结构的前进,合理性,和集中以后,我们在辽宁关于精力效率和工业结构的联合特征做了一些归纳,用联合的度等级模型。一些我们的结论如下:(1 ) 14 个城市在他们的精力效率显著地不同,与享受最高的精力效率的沈阳, Dalian,鞍山,和 Jinzhou。象 Fushun 和 Benxi 那样的西北的辽宁和另外的重工业的城市属于低效率、高消费的区域。(2 ) 在有更高的效率的区域,精力的空间模式技术效率,分别地,精力消费每 GDP,和精力利用效率联合起来是,塑造的 II 和 H- 。地理上,精力利用效率从东方显示出不同趋势到西方并且从北方到南方。象经济开发的 binuclear 结构那样的因素在精力效率的这个空间模式上有主要效果。(3 ) 东南的辽宁享受高度先进的工业结构。有高度合理的工业结构的区域形成 H 形状,与在二杆的沈阳和 Dalian。在中间、南部的辽宁的城市的凝块有高度集中的工业结构。(4 ) 总的来说,在精力效率和工业结构之间联合在辽宁是低的,除了在两结束的沈阳和 Dalian,在在先进工业结构和精力效率之间联合比在另外的城市里高的地方。 | GUAN Wei XU Shuting | 2015 | Journal of Geographical Sciences2015，25，3： | 8 |
| 2 | Highly active zigzag-like Pt-Zn alloy nanowires with high-index facets for alcohol electrooxidation显示文摘The development of highly efficient Pt-based alloy nanocatalysts is important but remains challenging for fuel cells commercialization.Here,a new class of zigzag-like platinum-zinc (Pt-Zn) alloy nanowires (NWs) with rough surface and controllable composition is reported.The merits of anisotropic one-dimensional nanostructure,stable high-index facets and coordinatively unsaturated Pt sites endow the composition-optimal Pt94Zn6 NWs with a mass activity of 7.2 and 6.2 times higher than that of commercial Pt black catalysts toward methanol/ethanol oxidation,respectively.Alloying-induced d-band electron modulation and lattice strain effects weaken the adsorption strength of poisoning species,which originally enhances the catalytic activity of Pt-Zn NWs.This study provides a new perspective of Pt-Zn electrocatalysts with intrinsic mechanism for enhanced catalytic performance. | Yanchao Xu Xiaoqiang Cui Shuting Wei Qinghua Zhang Lin Gu Fanqi Meng Jinchang Fan Weitao Zheng | 2019 | Nano Research2019，12，5： | 7 |
| 3 | Microcavity top-emission perovskite light-emitting diodes显示文摘Light-emitting diodes(LEDs)based on perovskites show great potential in lighting and display applications.However,although perovskite films with high photoluminescence quantum efficiencies are commonly achieved,the efficiencies of perovskite LEDs are largely limited by the low light out-coupling efficiency.Here,we show that high-efficiency perovskite LEDs with a high external quantum efficiency of 20.2% and an ultrahigh radiant exitance up to 114.9mWcm^(−2) can be achieved by employing the microcavity effect to enhance light extraction.The enhanced microcavity effect and light outcoupling efficiency are confirmed by the study of angle-dependent emission profiles.Our results show that both the optical and electrical properties of the device need to be optimized to achieve high-performance perovskite LEDs. | Yanfeng Miao Lu Cheng Wei Zou Lianghui Gu Ju Zhang Qiang Guo Qiming Peng Mengmeng Xu Yarong He Shuting Zhang Yu Cao Renzhi Li Nana Wang Wei Huang Jianpu Wang | 2020 | Light(Science & Applications)2020，9，1： | 4 |
| 4 | Quantized Phase Step Technique Based on Different Frequency Signals and Its Characteristics显示文摘 | DU Baoqiang DONG Shaofeng ZHOU Wei WANG Yanfeng GUO Shuting | 2013 | Chinese Journal of Electronics2013，22，3： | 4 |
| 5 | The formation of perovskite multiple quantum well structures for high performance light-emitting diodes显示文摘Recent works showed that high efficient perovskite light-emitting diodes can be achieved from solution-processed,self-organized multiple quantum wells(MQWs)with an energy cascade.We investigate how the mixing of QWs with different band gaps can affect the perovskite LED device performance.We find that the annealing process can significantly affect the constitution of the MQWs films,where the dominant phase can evolve from large band gap QWs to small band gap QWs.The optimal constitution for LED application lies in a transition point of small-n QWs dominant phase to large-n QWs dominant phase,when the MQW film presents highest photoluminescence while still remains uniform film morphology. | Yan Sun Li Zhang Nana Wang Shuting Zhang Yu Cao Yanfeng Miao Mengmeng Xu Hao Zhang Hai Li Chang Yi Jianpu Wang Wei Huang | 2018 | npj Flexible Electronics2018，2，1： | 4 |
| 6 | Isogeometric topology optimization based on energy penalization for symmetric structure显示文摘We present an energy penalization method for isogeometric topology optimization using moving morphable components(ITO–MMC),propose an ITO–MMC with an additional bilateral or periodic symmetric constraint for symmetric structures,and then extend the proposed energy penalization method to an ITO–MMC with a symmetric constraint.The energy penalization method can solve the problems of numerical instability and convergence for the ITO–MMC and the ITO–MMC subjected to the structural symmetric constraint with asymmetric loads.Topology optimization problems of asymmetric,bilateral symmetric,and periodic symmetric structures are discussed to validate the effectiveness of the proposed energy penalization approach.Compared with the conventional ITO–MMC,the energy penalization method for the ITO–MMC can improve the convergence rate from 18.6%to 44.5%for the optimization of the asymmetric structure.For the ITO–MMC under a bilateral symmetric constraint,the proposed method can reduce the objective value by 5.6%and obtain a final optimized topology that has a clear boundary with decreased iterations.For the ITO–MMC under a periodic symmetric constraint,the proposed energy penalization method can dramatically reduce the number of iterations and obtain a speedup of more than 2. | Xianda XIE Shuting WANG Ming YE Zhaohui XIA Wei ZHAO Ning JIANG Manman XU | 2020 | Frontiers of Mechanical Engineering2020，15，1： | 3 |
| 7 | Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer’s disease显示文摘Gene therapy represents a promising treatment for the Alzheimer’s disease(AD). However,gene delivery specific to brain lesions through systemic administration remains big challenge. In our previous work, we have developed an siRNA nanocomplex able to be specifically delivered to the amyloid plaques through surface modification with both CGN peptide for the blood–brain barrier(BBB)penetration and QSH peptide for β-amyloid binding. But, whether the as-designed nanocomplex could indeed improve the gene accumulation in the impaired neuron cells and ameliorate AD-associated symptoms remains further study. Herein, we prepared the nanocomplexes with an siRNA against β-site amyloid precursor protein-cleaving enzyme 1(BACE1), the rate-limiting enzyme of Aβ production, as the therapeutic siRNA of AD. The nanocomplexes exhibited high distribution in the Aβ deposits-enriched hippocampus, especially in the neurons near the amyloid plaques after intravenous administration. In APP/PS1 transgenic mice, the nanocomplexes down-regulated BACE1 in both mRNA and protein levels,as well as Aβ and amyloid plaques to the level of wild-type mice. Moreover, the nanocomplexes significantly increased the level of synaptophysin and rescued memory loss of the AD transgenic mice without hematological or histological toxicity. Taken together, this work presented direct evidences that the design of precise gene delivery to the AD lesions markedly improves the therapeutic outcome. | Qian Guo Xiaoyao Zheng Peng Yang Xiaoying Pang Kang Qian Pengzhen Wang Shuting Xu Dongyu Sheng Liuchang Wang Jinxu Cao Wei Lu Qizhi Zhang Xinguo Jiang | 2019 | Acta Pharmaceutica Sinica B2019，9，3： | 2 |
| 8 | 空间模式的学习和在中国的精力 eco 效率的空间效果显示文摘精力 eco 效率是集成从精力利用产生的生态、经济的好处的一个概念并且在 energy-environment-economy 系统用作效率的一项措施。就不受欢迎的输出而言用基于呆滞的措施(SBM ) 当模特儿,这研究首先从 1997 ~ 2012 在中国测量省的精力 eco 效率。它然后从三个方面分析精力 eco 效率的空间分发和进化:空间模式的规模,紧张,和谷物。最后,它借助于一个空间 econometric 模型在不同的省检验空间溢出效果和精力 eco 效率的影响因素。下列结论被得出:(1 ) 全面精力 eco 效率在中国是相对低的,与为大约 40% 的精力低效的区域财务。当 Ningxia, Gansu, Qinghai,和 Xinjiang 是有低效率的代表性的区域时,广东,海南和福建省享受最高的精力 eco 效率。因此,瓷器全面精力 eco 效率的进化的模式是 U 字形的。在本地区域之中,进化的四个主要模式被发现:增加,波动,变异,并且铺平。(2 ) 在省的水平,瓷器精力 eco 效率全球性并且局部地展示重要空间凝块。高高度的凝块主要在东方、南部的沿海的区域和低低的凝块发生在西北的区域和黄河的中间的活动范围。在空间模式的变化与高度低、低高度的凝块主要在区域发生了,与发生在 Beijing-Tianjin-Hebei 区域的最显著的变化。(3 ) 在那里存在在在中国的省之中的精力 eco 效率的重要空间效果。为一个给定的区域的精力 eco 效率,从邻近的区域的空间溢出在邻近的区域超过错误的影响。工业结构在精力 eco 效率上有最大的影响。 | GUAN Wei XU Shuting | 2016 | Journal of Geographical Sciences2016，26，9： | 2 |
| 9 | Nlrc3-like is required for microglia maintenance in zebrafish显示文摘Microglia are tissue-resident macrophages residing in the central nervous system (CNS) and play critical roles in removing cellular debris and infectious agents as well as regulating neurogenesis and neuronal activities. Yet, the molecular basis underlying the establishment of microglia pool and the maintenance of their homeostasis in the CNS remain largely undefined. Here we report the identification and characterization of a mutant zebrafish, which harbors a point mutation in the nucleotide-binding oligomerization domain (NOD) like receptor gene nlrc3-like, resulting in the loss of microglia in a temperature sensitive manner. Temperature shift assay reveals that the late onset of nlrc3-like deficiency leads to excessive microglia cell death. Further analysis shows that the excessive microglia death in nlrc3-like deficient mutants is attributed, at least in part, to aberrant activation of canonical inflammasome pathway. Our study indicates that proper regulation of inflammasome cascade is critical for the maintenance of microglia homeostasis. | Tienan Wang Bo Yan Liang Lou Xi Lin Tao Yu Shuting Wu Qing Lu Wei Liu Zhibin Huang Mingjie Zhang Wenqing Zhang Zilong Wen | 2019 | Journal of Genetics and Genomics2019，46，6： | 2 |
| 10 | Manipulations of micro/nanoparticles using gigahertz acoustic streaming tweezers显示文摘Contactless acoustic manipulation of micro/nanoscale particles has attracted considerable attention owing to its near independence of the physical and chemical properties of the targets,making it universally applicable to almost all biological systems.Thin-film bulk acoustic wave(BAW)resonators operating at gigahertz(GHz)frequencies have been demonstrated to generate localized high-speed microvortices through acoustic streaming effects.Benefitting from the strong drag forces of the high-speed vortices,BAW-enabled GHz acoustic streaming tweezers(AST)have been applied to the trapping and enrichment of particles ranging in size from micrometers to less than 100 nm.However,the behavior of particles in such 3D microvortex systems is still largely unknown.In this work,the particle behavior(trapping,enrichment,and separation)in GHz AST is studied by theoretical analyses,3D simulations,and microparticle tracking experiments.It is found that the particle motion in the vortices is determined mainly by the balance between the acoustic streaming drag force and the acoustic radiation force.This work can provide basic design principles for AST-based lab-on-a-chip systems for a variety of applications. | Hang Wu Zifan Tang Rui You Shuting Pan Wenpeng Liu Hongxiang Zhang Tiechuan Li Yang Yang Chongling Sun Wei Pang Xuexin Duan | 2022 | Nanotechnology and Precision Engineering2022，5，2： | 1 |
| 11 | Molecularly imprinted micro and nanospheres for the selective recognition of 17β-estradiol显示文摘 | WEI Shuting MOLINELLI A MIZAIKOFF B | 2006 | Biosens Bioelectron2006，21，： | 1 |
| 12 | Development of pretreatment protocol for DNA extraction from biofilm attached to biologic activated carbon(BAC)granules显示文摘The biologic activated carbon(BAC)process is widely used in drinking water treatments.A comprehensive molecular analysis of the microbial community structure provides very helpful data to improve the reactor performance.However,the bottleneck of deoxyribonucleic acid(DNA)extraction from BAC attached biofilm has to be solved since the conventional procedure was unsuccessful due to firm biomass attachment and adsorption capacity of the BAC granules.In this study,five pretreatments were compared,and adding skim milk followed by ultrasonic vibration was proven to be the optimal choice.This protocol was further tested using the vertical BAC samples from the full-scale biofilter of Pinghu Water Plant.The results showed the DNAyielded a range of 40μg·g^(-1) BAC(dry weight)to over 100μg·g^(-1) BAC(dry weight),which were consistent with the biomass distribution.All results suggested that the final protocol could produce qualified genomic DNA as a template from the BAC filter for downstream molecular biology researches. | Shuting ZHANG Bo WEI Xin YU Bing LIU Zhuoying WU Li GU | 2010 | Frontiers of Environmental Science & Engineering2010，4，4： | 1 |
| 13 | Molecularly imprinted micro and nanospheres for the selective recognition of 17-estradiol显示文摘 | Wei Shuting Alexandra Molinelli Boris Mizaikoff | 2006 | Biosensors and Bioelectronics2006，，21： | 1 |
| 14 | Capturing molecules with templated materils-Analysis and rational design of molecularly imprinted polymers显示文摘 | Wei Shuting Michael Jakusch Boris Mizaikoff | 2006 | Analytica Chimica Acta2006，578，1： | 1 |
| 15 | Primary assessment of the diversity of Omicron sublineages and the epidemiologic features of autumn/winter 2022 COVID-19 wave in Chinese mainland显示文摘With the recent ongoing autumn/winter 2022 COVID-19 wave and the adjustment of public health control measures,there have been widespread SARS-CoV-2 infections in Chinese mainland.Here we have analyzed 369 viral genomes from recently diagnosed COVID-19 patients in Shanghai,identifying a large number of sublineages of the SARS-CoV-2 Omicron family.Phylogenetic analysis,coupled with contact history tracing,revealed simultaneous community transmission of two Omicron sublineages dominating the infections in some areas of China(BA.5.2 mainly in Guangzhou and Shanghai,and BF.7 mainly in Beijing)and two highly infectious sublineages recently imported from abroad(XBB and BQ.1).Publicly available data from August 31 to November 29,2022 indicated an overall severe/critical case rate of 0.035%nationwide,while analysis of 5706 symptomatic patients treated at the Shanghai Public Health Center between September 1 and December 26,2022 showed that 20 cases(0.35%)without comorbidities progressed into severe/critical conditions and 153 cases(2.68%)with COVID-19-exacerbated comorbidities progressed into severe/critical conditions.These observations shall alert healthcare providers to place more resources for the treatment of severe/critical cases.Furthermore,mathematical modeling predicts this autumn/winter wave might pass through major cities in China by the end of the year,whereas some middle and western provinces and rural areas would be hit by the upcoming infection wave in mid-to-late January 2023,and the duration and magnitude of upcoming outbreak could be dramatically enhanced by the extensive travels during the Spring Festival(January 21,2023).Altogether,these preliminary data highlight the needs to allocate resources to early diagnosis and effective treatment of severe cases and the protection of vulnerable population,especially in the rural areas,to ensure the country’s smooth exit from the ongoing pandemic and accelerate socio-economic recovery. | Gang Lu Yun Ling Minghao Jiang Yun Tan Dong Wei Lu Jiang Shuting Yu Fangying Jiang Shuai Wang Yao Dai Jinzeng Wang Geng Wu Xinxin Zhang Guoyu Meng Shengyue Wang Feng Liu Xiaohong Fan Saijuan Chen | 2023 | Frontiers of Medicine2023，17，4： | 1 |
| 16 | Molecularly imprinted micro and nanospheres for the selective recognition of 17β- estradiol 显示文摘 | Wei Shuting Alexandra M Boris M | 2006 | Biosensors and Bioelectronics2006，21，10： | 1 |
| 17 | Host protection against Omicron BA.2.2 sublineages by prior vaccination in spring 2022 COVID-19 outbreak in Shanghai显示文摘The Omicron family of SARS-CoV-2 variants are currently driving the COVID-19 pandemic.Here we analyzed the clinical laboratory test results of 9911 Omicron BA.2.2 sublineages-infected symptomatic patients without earlier infection histories during a SARS-CoV-2 outbreak in Shanghai in spring 2022.Compared to an earlier patient cohort infected by SARS-CoV-2 prototype strains in 2020,BA.2.2 infection led to distinct fluctuations of pathophysiological markers in the peripheral blood.In particular,severe/critical cases of COVID19 post BA.2.2 infection were associated with less pro-inflammatory macrophage activation and stronger interferon alpha response in the bronchoalveolar microenvironment.Importantly,the abnormal biomarkers were significantly subdued in individuals who had been immunized by 2 or 3 doses of SARS-CoV-2 prototypeinactivated vaccines,supporting the estimation of an overall 96.02% of protection rate against severe/critical disease in the 4854 cases in our BA.2.2 patient cohort with traceable vaccination records.Furthermore,even though age was a critical risk factor of the severity of COVID-19 post BA.2.2 infection,vaccination-elicited protection against severe/critical COVID-19 reached 90.15% in patients aged≥60 years old.Together,our study delineates the pathophysiological features of Omicron BA.2.2 sublineages and demonstrates significant protection conferred by prior prototype-based inactivated vaccines. | Ziyu Fu Dongguo Liang Wei Zhang Dongling Shi Yuhua Ma Dong Wei Junxiang Xi Sizhe Yang Xiaoguang Xu Di Tian Zhaoqing Zhu Mingquan Guo Lu Jiang Shuting Yu Shuai Wang Fangyin Jiang Yun Ling Shengyue Wang Saijuan Chen Feng Liu Yun Tan Xiaohong Fan | 2023 | Frontiers of Medicine2023，17，3： | 1 |
| 18 | Comparison of the community structures of ammonia-oxidizing bacteria and archaea in rhizoplanes of floating aquatic macrophytes显示文摘 | Bo Wei Xin Yu Shuting Zhang Li Gu | 2010 | Microbiological Research2010，，6： | 1 |
| 19 | Copper-linked IT MoS2/Cu2O Heterostructure for Efficient Photocatalytic Hydrogen Evolution显示文摘Metallic IT phase molybdenum disulfide(lT MoS2)is an excellent catalyst due to the abundant active sites and good conductivity.However,complex synthesis and unstable nature of IT MoS2 still limit its practical application.Herein,we propose a simple method to trigger the phase transition of MoS2.This phase transition is first predicted by density functional theory(DFT)calculations and then confirmed by Raman spectroscopy and high-resolution transmission electron microscopy(HRTEM).IT MoS2/CU2O heterostructure catalyst is then developed,showing enhanced photocatalytic hydrogen evolution. | YIN Yage WEI Shuting ZHANG Lei GUO Ziwang HUANG Haihua SAl Shiran WU Jiandong XU Yanchao LIU Ying ZHENG Lirong FAN Xiaofeng CUI Xiaogiang | 2020 | Chemical Research in Chinese Universities2020，36，6： | 0 |
| 20 | Spatial-temporal heterogeneity and determinants of HIV prevalence in the Mano River Union countries显示文摘Background:Utilizing population-based survey data in epidemiological research with a spatial perspective can integrate valuable context into the dynamics of HIV prevalence in West Africa.However,the situation in the Mano River Union(MRU)countries is largely unknown.This research aims to perform an ecological study to determine the HIV prevalence patterns in MRU.Methods:We analyzed Demographic and Health Survey(DHS)and AIDS Indicator Survey(AIS)data on HIV prevalence in MRU from 2005 to 2020.We examined the country-specifc,regional-specifc and sex-specifc ratios of respondents to profle the spatial–temporal heterogeneity of HIV prevalence and determine HIV hot spots.We employed Geodetector to measure the spatial stratifed heterogeneity(SSH)of HIV prevalence for adult women and men.We assessed the comprehensive correct knowledge(CCK)about HIV/AIDS and HIV testing uptake by employing the Least Absolute Shrinkage and Selection Operator(LASSO)regression to predict which combinations of CCKs can scale up the ratio of HIV testing uptake with sex-specifc needs.Results:In our analysis,we leveraged data for 158,408 respondents from 11 surveys in the MRU.From 2005–2015,Cote d’Ivoire was the hot spot for HIV prevalence with a Gi_Bin score of 3,Z-Score 8.0–10.1 and P<0.001.From 2016 to 2020,Guinea and Sierra Leone were hot spots for HIV prevalence with a Gi_Bin score of 2,Z-Score of 3.17 and P<0.01.The SSH confrmed the signifcant diferences in HIV prevalence at the national level strata,with a higher level for Cote d’Ivoire compared to other countries in both sexes with q-values of 0.61 and 0.40,respectively.Our LASSO model predicted diferent combinations of CCKs with sex-specifc needs to improve HIV testing uptake.Conclusions:The spatial distribution of HIV prevalence in the MRU is skewed and the CCK about HIV/AIDS and HIV testing uptake are far below the threshold target set by UNAIDS for ending the epidemic in the sub-region.Geodetector detected statistically signifcant SSH within and between countries in the MRU.Our LASSO model predicted that diferent emphases should be implemented when popularizing the CCK about HIV/AIDS for adult women and men. | Idrissa Laybohr Kamara Liang Wang Yaxin Guo Shuting Huo Yuanyuan Guo Chengdong Xu Yilan Liao William J.Liu Wei Ma George F.Gao | 2022 | Infectious Diseases of Poverty2022，11，6： | 0 |
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