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| 1 | Passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts and assessment of clinical outcomes显示文摘AIM To assess for passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts(TIPS) and compare outcomes with maximally dilated TIPS.METHODS Polytetrafluoroethylene covered TIPS(Viatorr) from July 2002 to December 2013 were retrospectively reviewed at two hospitals in a single institution. Two hundred and thirty patients had TIPS maximally dilated to 10 mm(m TIPS), while 43 patients who were at increased risk for hepatic encephalopathy(HE), based on clinical evaluation or low pre-TIPS portosystemic gradient(PSG), had 10 mm TIPS sub-maximally dilated to 8 mm(sm TIPS). Group characteristics(age, gender, Model for End-Stage Liver Disease score, post-TIPS PSG and clinical outcomes were compared between groups, including clinical success(ascites or varices), primary patency,primary assisted patency, and severe post-TIPS HE. A subset of fourteen patients with sm TIPS underwent follow-up computed tomography imaging after TIPS creation, and were grouped based on time of imaging(< 6 mo and > 6 mo). Change in diameter and crosssectional area were measured with 3D imaging software to evaluate for passive expansion.RESULTS Patient characteristics were similar between the sm TIPS and m TIPS groups, except for pre-TIPS portosystemic gradient, which was lower in the sm TIPS group(19.4 mm Hg ± 6.8 vs 22.4 mm Hg ± 7.1, P = 0.01). Primary patency and primary assisted patency between sm TIPS and m TIPS was not significantly different(P = 0.64 and 0.55, respectively). Four of the 55 patients(7%) with sm TIPS required TIPS reduction for severe refractory HE, while this occurred in 6 of the 218 patients(3%) with m TIPS(P = 0.12). For the 14 patients with follow-up computed tomography(CT) imaging, the median imaging follow-up was 373 d. There was an increase in median TIPS diameter, median percent diameter change, median area, and median percent area change in patients with CT follow-up greater than 6 mo after TIPS placement compared to follow-up within 6 mo(8.45 mm, 5.58%, 56.04 mm^2, and 11.48%, respectively, P = 0.01).CONCLUSION Passive expansion of sm TIPS does occur but clinical outcomes of sm TIPS and m TIPS were similar. Sub-maximal dilation can prevent complications related to overshunting in select patients. | Michael C Hsu Charles N Weber S William Stavropoulos Timothy W Clark Scott O Trerotola Richard D Shlansky Goldberg Michael C Soulen Gregory J Nadolski | 2017 | World Journal of Hepatology2017，9，12： | 11 |
| 2 | Standardized surgery for colonic cancer:complete mesocolic excision and central ligation-technical notes and outcome显示文摘 | Hohenberger W Weber K Matzel K | | 0，，04： | 2 |
| 3 | 奈必洛尔和缬沙坦固定剂量联合治疗高血压的疗效与安全性研究显示文摘任意2类降压药物固定剂量联合降压作用强于单独增加一类药物剂量的作用。该研究评估β受体阻滞剂奈必洛尔(nebivolol)和血管紧张素受体拮抗剂缬沙坦(valsartan)固定剂量联合治疗成人高血压的疗效与安全性。方法:研究人员在美国401个医疗中心进行了为期8周、临床试验3期、多中心、随机、双盲、安慰剂平行对照试验。参与者均为≥18岁的高血压患者(但血压≤180/110mm Hg,1mm Hg=0.133kPa),以15例为一治疗组, | 刘莉 叶鹏 Giles TD Weber MA Basile J Gradman AH Bharucha DB Chen W Pattathil M | 2014 | 中华高血压杂志2014，22，8： | 2 |
| 4 | Which Time-to-Peak Threshold Best Identifies Penumbral Flow?: A Comparison of Perfusion-Weighted Magnetic Resonance Imaging and Positron Emission Tomography in Acute Ischemic Stroke显示文摘 | J Sobesky O Zaro Weber F -G. Lehnhardt V Hesselmann A Thiel C Dohmen A Jacobs M Neveling W -D. Heiss | 2004 | Stroke2004，，12： | 2 |
| 5 | SLALOM:Semiconductor laser amplifier in a loop mirror显示文摘 | Eiselt M Pieper W Weber H G | | 0，，： | 2 |
| 6 | Stent-angioplasty of intracranial vertebral and basilar artery stenoses in symptomatic patients 显示文摘 | Weber W Mayer TE Henkes H | 2005 | Eur J Radiol2005，55，2： | 1 |
| 7 | Measurement of excited-state-absorption loss for Ce^3+ in Y3Al5O12 and implications for tunable 5d→4f rare earth laser显示文摘 | Jacobs R R Krupke W F Weber M | 1978 | J Appl Phys Lett(S0003-6951)1978，，33： | 1 |
| 8 | Photopoly-met8 for holography显示文摘 | Smothers W K Monroe R M Weber A M | 1990 | SPIE1990，1212，： | 1 |
| 9 | Seed yield losses from lodging combine harvesting in soybeans 显示文摘 | Weber C R Fehr W R | 1966 | Agronomy Journal1966，58，： | 1 |
| 10 | 3-Hydroxypropionic acid as a nematicidal principle in endophytic fungi显示文摘 | Michael Schwarz Barbel Kopcke Roland W S Weber | 2004 | Phytochemistry2004，65，： | 1 |
| 11 | Effect of ecological factors on the inhibitory spectrum and activity of bacteriocins 显示文摘 | Ganzle M G Weber S Hammes W P | 1999 | Intemational Journal of Food Microbiology1999，48，： | 1 |
| 12 | Identification of molecular markers linked to Rdrl,a gene conferring resistance to blackspot in roses显示文摘 | Von Malek B Weber W E Debener T | 2000 | Theor Appl Genet2000，101，： | 1 |
| 13 | Inhibitors of protein tyrosine kinase suppress TNF-stimulated induction of endothelial cell adhesion molecules 显示文摘 | WEBER C NEGRESCU E ERL W | 1995 | The Journal of Immunology1995，155，1： | 1 |
| 14 | Improved acid neutralisation capacity assessment of iron carbonates by titration and theoretical calculation显示文摘 | Weber P A Thomas J E Skinner W M | 2004 | Applied Geochemistry2004，19，： | 1 |
| 15 | UV Laser Polishing of Thick Diamond Films for IR Windows 显示文摘 | S Gloor W Luthy H P Weber | 1999 | Aplied Surface Science1999，，138139： | 1 |
| 16 | Pharmaeokinetics of galanthamine in humans and corresponding cholinesterase inhibition显示文摘 | Bickel U Thomsen T Weber W | 1991 | Clin Pharmacol Ther1991，50，4： | 1 |
| 17 | Toxic spongiform leucoencephalopathy after inhaling heroin vapour显示文摘 | Weber W Henkes H Moller P | 1998 | Eur Radiol1998，8，5： | 1 |
| 18 | Enhancement of transport critical current densities in (Bi,Pb)2Sr2Ca2Cu3O10/Ag tapes at 77K following fast neutron irradiation显示文摘 | HC Q Y WEBER H W SAUERZOPF F M | 1994 | Appl Phys Lett1994，65，4： | 1 |
| 19 | Ocean Surface Currents Mapped by Radar显示文摘 | Barrick D E Evans M W Weber B L | 1977 | Science1977，198，： | 1 |
| 20 | Vendor Selection Criteria and Methods显示文摘 | Weber C A Current J R Benton W C | 1991 | European Journal of Operational Research1991，50，： | 1 |
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