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1得与失:苦苣苔科新的属级界定与分类系统——中国该科植物之变迁(英文)显示文摘过去20年对苦苣苔科植物的分子系统学研究已经极大地拓展了对这个科的种间关系与属一级之界定的理解。该文提供了一个苦苣苔科植物新分类系统,与传统的经典形态学分类系统比较,这一新系统被认为能更好地反映科下分类单元彼此之间的自然关系。众多传统意义上的属被分割、合并或者重新定义,这些巨大的分类变动正在影响着中国的苦苣苔科植物系统分类。此外,基于最近采集的材料,一些新属得以建立,一方面说明在中国还有相当多的野外工作需要做;而另一方面则再次证明了中国的苦苣苔科植物多样性是如此之丰富。在此,针对目前已经完成的工作和分类结论,对中国苦苣苔科植物的新分类系统进行了总结与概述,并深入地讨论了部分传统分类学上存在困惑的疑难属。MOLLER Michael 韦毅刚 温放 CLARK John L. WEBER Anton 2016广西植物2016,36,1:35
2加拿大一枝黄花在中国的潜在入侵区预测(英文)显示文摘加拿大一枝黄花Solidago canadensis是原产于北美的菊科Asteraceae多年生草本植物, 上世纪30年代引入我国, 现广泛分布于我国东部地区的部分省市, 并已成为该区域的农业和环境杂草。为了预测加拿大一枝黄花在我国的潜在分布区, 本研究采用相同气候方法对其进行了估测。我们用加拿大一枝黄花的原产地——美国的气候参数作为参照, 将其与我国各地气象站的气候数据进行匹配。结果表明, 加拿大一枝黄花在我国的潜在分布区的纬度跨度为25°–50°, 所以其潜在的入侵区将远大于目前的实际分布区, 甚至东北的部分地区也将适宜于该物种的生长。据此, 我们建议相关管理部门应加强该物种的监测工作, 以防其进一步向目前入侵区以外的周边地区蔓延。陆建忠 翁恩生 吴晓雯 Ewald WEBER 赵斌 李博 2007植物分类学报2007,45,5:27
3血管内超声去肾交感神经术治疗高血压:一项多中心,国际,单盲,随机,假手术对照试验显示文摘早期研究表明,基于射频的去肾交感神经术可降低中度高血压患者的血压。研究者研究了在没有使用抗高血压药物的情况下,使用血管内超声去。肾交感神经术是否会降低高血压患者的动态血压。刘青 叶鹏 Azizi M Schmieder RE Mahfoud F Weber MA Daemen J Davies J Basile J Kirtane AJ Wang Y Lobo MD Saxena M Feyz L Rader F Lurz P Sayer J Sapoval M Levy T Sanghvi K Abraham J Sharp ASP Fisher NDL Bloch MJ Reeve-Stoffer H Coleman L Mullin C Mauri L 2018中华高血压杂志2018,26,10:27
4Chemokine expression in hepatocellular carcinoma versus colorectal liver metastases显示文摘AIM: To evaluate and compare the expression profiles of CXCL12 (SDF-1), CCL19 (MIP-3β), CCL20 (MIP-3α) and CCL21 (6Ckine, Exodus2) and their receptors on RNA and protein levels in hepatocellular carcinoma (HCC) versus colorectal liver metastases (CRLM) and to elucidate their impact on the carcinogenesis and progression of malignant liver diseases. METHODS: Chemokine expression was analyzed by RT-PCR and ELISA in 11 cases of HCC specimens and in 23 cases of CRLM and corresponding adjacent non- tumorous liver tissues, respectively. Expressions of their receptors CXCR4, CCR6 and CCR7 were analyzed by RT- PCR and Western blot analysis in the same cases of HCC and CRLM. RESULTS: Significant up-regulation for CCL20/CCR6 was detected in both cancer types. Moreover, CCL20 demonstrated significant overexpression in CRLM in relation to the HCC tissues. Being significantly up- regulated only in CRLM, CXCR4 displayed an aberrant expression pattern with respect to the HCC tissues. CONCLUSION: Correlation of CXCR4 expression with CRLM suggests CXCR4 as a potential predictive factor for CRLM. High level expression of CCL20 and its receptor CCR6 in HCC and CRLM with marked up- regulation of CCL20 in CRLM in relation to HCC tissues indicates involvement of the CCL20/CCR6 ligand-receptor pair in the carcinogenesis and progression of hepatic malignancies.Claudia Rubie Vilma Oliveira Frick Mathias Wagner Christina Weber Bianca Kruse Katja Kempf Jochen Knig Bettina Rau Martin Schilling 2006World Journal of Gastroenterology2006,12,41:24
5Long-term outcome and prognostic factors of patients with hilar cholangiocarcinoma显示文摘AIM: To evaluate the long-term outcome and prognostic factors of patients with hilar cholangiocarinoma. METHODS: Ninety-six consecutive patients underwent treatment for malignant hilar bile duct tumors during 1995–2005. Of the 96 patients, 20 were initially treated with surgery (n = 2 R0 / n = 18 R1). In non-operated patients, data analysis was performed retrospectively. RESULTS: Among the 96 patients, 76 were treated with endoscopic transpapillary (ERC, n = 45) and/or percutaneous transhepatic biliary drainage (PTBD, n = 31). The mean survival time of these 76 patients undergoing palliative endoscopic and/or percutaneous drainage was 359 ± 296 d. The mean survival time of patients with initial bilirubin levels > 10 mg/dL was significantly lower (P < 0.001) than patients with bilirubin levels < 10 mg/dL. The mean survival time of patients with Bismuth stage Ⅱ (n = 8), Ⅲ (n = 28) and Ⅳ (n = 40) was 496 ± 300 d, 441 ± 385 d and 274 ± 218 d, respectively. Thus, patients with advanced Bismuth stage showed a reduced mean survival time, but the difference was not significant. The type of biliary drainage had no significant beneficial effect on the mean survival time (ERC vs PTBD, P = 0.806). CONCLUSION: Initial bilirubin level is a significant prognostic factor for survival of patients. In contrast, age, tumor stage according to the Bismuth-Corlette classification, and types of intervention are not significant prognostic parameters for survival. Palliative treatment with endoscopic or percutaneous biliary drainage is still suboptimal, new diagnostic and therapeutic tools need to be evaluated.Andreas Weber Sonja Landrock Jochen Schneider Manfred Stangl Bruno Neu Peter Born Meinhard Classen Thomas Rsch Roland M Schmid Christian Prinz 2007World Journal of Gastroenterology2007,13,9:23
6Diagnostic approaches for cholangiocarcinoma显示文摘Cholangiocarcinomas arise from the epithelial cells of the bile ducts and are associated with poor prognosis. Despite new diagnostic approaches, the definite diagnosis of this malignancy continues to be challenging. Cholangiocarcinomas often grow longitudinally along the bile duct rather than in a radial direction. Thus, large tumor masses are frequently absent and imaging techniques, including ultrasound, CT, and MRI have only limited sensitivity. Tissue collection during endoscopic (ERCP) and/or percutaneous transhepatic (PTC) procedures are usually used to confirm a definitive diagnosis of cholangiocarcinoma. However, forceps biopsy and brush cytology provide positive results for malignancy in about only 50% of patients. Percutaneous and peroral cholangioscopy using fiber-optic techniques were therefore developed for direct visualization of the biliary tree, yielding additional information about endoscopic appearance and tumor extension, as well as a guided biopsy acquistion. Finally, endoscopic ultrasonography (EUS) complements endoscopic and percutaneous approaches and may provide a tissue diagnosis of tumors in the biliary region through fine-needle aspiration. In the future, new techniques allowing for early detection, including molecular markers, should be developed to improve the diagnostic sensitivity in this increasing tumor entity.Andreas Weber Roland M Schmid Christian Prinz 2008World Journal of Gastroenterology2008,14,26:21
7In vitro activity of moxifloxacin and piperacillin/sulbactam against pathogens of acute cholangitis显示文摘AIM: To analyze the in vitro activity of moxifloxacin and piperacillin/sulbactam against pathogens isolated from patients with acute cholangitis. METHODS: In this prospective study a total of 65 patients with acute cholangitis due to biliary stone obstruction (n = 7), benign biliary stricture (n = 16), and malignant biliary stricture (n = 42) were investigated with regard to spectrum of bacterial infection and antibiotic resistance. Pathogens were isolated from bile cultures in all study patients. In 22 febrile patients, blood cultures were also obtained. In vitro activity of moxifloxacin and piperacillin/ sulbactam was determined by agar diffusion. RESULTS: Thirty-one out of 65 patients had positive bile and/or blood cultures. In 31 patients, 63 isolates with 17 different species were identified. The predominant strains were Enterococcus species (26/63), E.coli (13/63) and Klebsiella species (8/63). A comparable in vitro activity of moxifloxacin and piperacillin/sulbactam was observed for E.coli and Klebsiella species. In contrast, Enterococcus species had higher resistances towards moxifloxacin. Overall bacteria showed antibiotic resistances in vitro of 34.9% for piperacillin/sulbactam and 36.5% for moxifloxacin.CONCLUSION: Enterococcus species , E.coli and Klebsiella species were the most common bacteria isolated from bile and/or blood from patients with acute cholangitis. Overall, a mixed infection with several species was observed, and bacteria showed a comparable in vitro activity for piperacillin/sulbactam and moxifloxacin.Andreas Weber Wolfgang Huber Klaus Kamereck Philipp Winkle Petra Voland Hans Weidenbach Roland M Schmid Christian Prinz 2008World Journal of Gastroenterology2008,14,20:18
8Endoscopic transpapillary brush cytology and forceps biopsy in patients with hilar cholangiocarcinoma显示文摘AIM: To evaluate the sensitivity of brush cytology and forceps biopsy in a homogeneous patient group with hilar cholangiocarcinoma.METHODS: Brush cytology and forceps biopsy were routinely performed in patients with suspected malignant biliary strictures. Fifty-eight consecutive patients undergoing endoscopic retrograde cholangio-pancreatography (ERCP) including forceps biopsy and brush cytology in patients with hilar cholangiocarcinoma between 1995-2005.RESULTS: Positive results for malignancy were obtained in 24/58 patients (41.4%) by brush cytology and in 31/58 patients (53.4%) by forceps biopsy. The combination of both techniques brush cytology and forceps biopsy resulted only in a minor increase in diagnostic sensitivity to 60.3% (35/58 patients). In 20/58 patients (34.5%), diagnosis were obtained by both positive cytology and positive histology, in 11/58 (19%) by positive histology (negative cytology) and only 4/58 patients (6.9%) were confirmed by positive cytology (negative histology).CONCLUSION: Brush cytology and forceps biopsy have only limited sensitivity for the diagnosis of malignant hilar tumors. In our eyes, additional diagnostic techniques should be evaluated and should become routine in patients with negative cytological and histological findings.Andreas Weber Claus von Weyhern Falko Fend Jochen Schneider Bruno Neu Alexander Meining Hans Weidenbach Roland M Schmid Christian Prinz 2008World Journal of Gastroenterology2008,14,7:17
9高危患者目标血压与心血管病预后显示文摘指南推荐血压目标值应〈140/90 mmHg(1mmHg=0.133kPa)以减少心血管事件的发生。但与其他心血管病预后(如冠状动脉事件)相比,包括脑卒中及心力衰竭在内的心血管病预后与收缩压下降关系更密切。一些心血管事件(如冠状动脉事件)风险在收缩压低时亦增高,风险-收缩压关系呈J形曲线,而脑卒中与血压不是J形曲线关系。B?hm M Schumacher H Teo KK Lonn EM Mahfoud F Mann JF Mancia G Redon J Schmieder RE Sliwa K Weber MA Williams BYusuf S 曲浥晨 叶鹏 2017中华高血压杂志2017,25,6:14
10赤豆荚果总黄酮提取物对原代培养大鼠肝细胞氧化损伤的保护作用显示文摘目的:探讨赤豆荚果总黄酮提取物抗氧化作用以及对培养大鼠原代肝细胞氧化损伤的保护作用。方法:采用Photochem抗氧化测定仪对赤豆荚果总黄酮提取物体外抗氧化作用进行评价,同时评价其对培养大鼠原代肝细胞Fe2+氧化损伤保护作用的量效、时效关系。结果:赤豆荚果总黄酮提取物具有较强的抗氧化作用,在40,80,120ng剂量下,抗氧化作用大于芹菜素(P<0.05)。培养的原代肝细胞中加入100 μmol/L Fe2+后肝细胞活性减弱,培养液中ALT活力升高(P<0.05),脱落明显。加入提取物后,可有效抑制上述损伤作用。论:赤豆荚果总黄酮提取物具有较强的体外抗氧化作用,对Fe2+导致的大鼠原代肝细胞氧化损伤具有保护作用。李波 赵青威 Nadine Weber 楼宜嘉 Peter Proksch 2005营养学报2005,27,5:13
11恶性黑色素瘤的免疫治疗进展显示文摘黑色素瘤是常发于皮肤、进展声速的恶性肿瘤。近几十年来该病的发病率和死亡率均呈现上升趋势。2011年全球约诊断出70230例新发恶性黑色素瘤病例,Jeffrey Weber 2012中国肿瘤临床2012,29,9:13
12BAYQIK~——高浓度二氧化硫烟气制酸创新工艺显示文摘介绍拜耳技术服务公司开发的准等温接触高浓度二氧化硫烟气制酸创新工艺BAYQIK。详述该工艺的理论基础、反应器结构、模型建立、中间试验以及在铅冶炼烟气制酸装置中的应用。BAYQIK艺的特点在于采用列管式固定床反应器,传统钒催化剂装在管内,冷却介质在壳程流动。氧化过程放出的热量被连续移走,从而使催化剂始终处于可承受的最高温度以下,即使反应器进气φ(SO2)超过50%。BAYQIK工艺可提供各种经济和工艺优点,包括可降低投资与操作成本,对于新建装置和扩能改造项目同样适用。T. WEBER M. KUERTEN B. ERKES K. STEMMER 段立文(译) 2010硫酸工业2010,,1:12
13Can inhibin-B predict the outcome of microsurgical epididymal sperm aspiration in patients with suspected primary obstructive azoospermia?显示文摘瞄准:评估 inhibin-B 是否能预言 microsurgicalepidymal 精子渴望(方山) 的结果在有怀疑的主要妨碍的精子缺乏(OA ) 的病人的过程并且如果 inhibin-B 能在这些病人的诊断病情的检查代替阴囊的活体检视。方法:Inhibin-B 层次和阴囊的活体检视分数与有怀疑的主要 OA 的 MESAin 43 病人的结果有关。当 epididymalsperm 能在过程期间被识别时,方山被认为成功。结果:精子从 43 个病人(65%) 在在 28 的 epididymalaspirate 是在场的。Inhibin-B 价值不是有成功或失败的方山的显著地不同的住院病人。然而,修改 Johnsen 分数在有失败的方山的病人是显著地更低的(P = 0.003 ) 。失灵的睾丸网阻塞 orepididymal 与怀疑的主要 OA 在 15% 病人被发现,尽管有正常 inhibin-B 层次和正常阴囊的组织学,由失败的方山思考了。结论: Inhibin-B 不能用怀疑的主要 OA 在病人的病情的检查作为一个诊断工具代替阴囊的活体检视。阴囊的活体检视在识别可能有正常 inhibin-B 价值的有精子发生的拘捕的病人是有用的。Marij Smit Gert R. Dohle Mark F. Wildhagen Rob F. A. Weber 2007Asian Journal of Andrology2007,9,3:12
14激光光束传输因子M^2的一些问题显示文摘本文讨论与 M2 因子有关的一些问题 ,指出在近轴近似条件下由光束的二阶强度矩定义的 M2 因子满足 M2 ≥ 1 ,其中只有对基模高斯光束等式才成立 .由光束的功率通量值定义的 M2 因子 ( M2pc)有可能小于 1 ,M2pc的大小取决于所定义的光斑半径内包含的光功率的百分数 .通过计算光场的二阶矩 ,我们获得了轴向相干叠加的高斯光束的 M2高春清 Weber Horst 2001光子学报2001,30,2:11
15Passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts and assessment of clinical outcomes显示文摘AIM To assess for passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts(TIPS) and compare outcomes with maximally dilated TIPS.METHODS Polytetrafluoroethylene covered TIPS(Viatorr) from July 2002 to December 2013 were retrospectively reviewed at two hospitals in a single institution. Two hundred and thirty patients had TIPS maximally dilated to 10 mm(m TIPS), while 43 patients who were at increased risk for hepatic encephalopathy(HE), based on clinical evaluation or low pre-TIPS portosystemic gradient(PSG), had 10 mm TIPS sub-maximally dilated to 8 mm(sm TIPS). Group characteristics(age, gender, Model for End-Stage Liver Disease score, post-TIPS PSG and clinical outcomes were compared between groups, including clinical success(ascites or varices), primary patency,primary assisted patency, and severe post-TIPS HE. A subset of fourteen patients with sm TIPS underwent follow-up computed tomography imaging after TIPS creation, and were grouped based on time of imaging(< 6 mo and > 6 mo). Change in diameter and crosssectional area were measured with 3D imaging software to evaluate for passive expansion.RESULTS Patient characteristics were similar between the sm TIPS and m TIPS groups, except for pre-TIPS portosystemic gradient, which was lower in the sm TIPS group(19.4 mm Hg ± 6.8 vs 22.4 mm Hg ± 7.1, P = 0.01). Primary patency and primary assisted patency between sm TIPS and m TIPS was not significantly different(P = 0.64 and 0.55, respectively). Four of the 55 patients(7%) with sm TIPS required TIPS reduction for severe refractory HE, while this occurred in 6 of the 218 patients(3%) with m TIPS(P = 0.12). For the 14 patients with follow-up computed tomography(CT) imaging, the median imaging follow-up was 373 d. There was an increase in median TIPS diameter, median percent diameter change, median area, and median percent area change in patients with CT follow-up greater than 6 mo after TIPS placement compared to follow-up within 6 mo(8.45 mm, 5.58%, 56.04 mm^2, and 11.48%, respectively, P = 0.01).CONCLUSION Passive expansion of sm TIPS does occur but clinical outcomes of sm TIPS and m TIPS were similar. Sub-maximal dilation can prevent complications related to overshunting in select patients.Michael C Hsu Charles N Weber S William Stavropoulos Timothy W Clark Scott O Trerotola Richard D Shlansky Goldberg Michael C Soulen Gregory J Nadolski 2017World Journal of Hepatology2017,9,12:11
16炎症与癌症:肿瘤的发生、进展和转移以及中药植物药(英文)显示文摘古往今来,癌症都被视为一个炎症过程。过去20多年的研究已经从分子水平证实大部分慢性疾病包括癌症都是由炎症反应失调所引起的。转录因子如核因子κB与信号转导和转录激活因子3以及它们的基因产物如肿瘤坏死因子、白细胞介素1、白细胞介素6、趋化因子、环氧合酶2、血管内皮生长因子、黏附分子等的发现为阐释炎症在癌症过程中的作用提供了分子基础。肿瘤的发生、发展和转移以及机体无法对其产生免疫抑制都可以部分地用慢性全身炎症反应来解释。中药用于治疗癌症及炎症具有悠久的历史。本文介绍了近期有关癌症与炎症的研究进展以及用于治疗癌症的中药和中药复方。Daniel Weber Janelle M Wheat Geoffrey M Currie 2010中西医结合学报2010,8,11:10
17The secondary metabolite bioinformatics portal: Computational tools to facilitate synthetic biology of secondary metabolite production显示文摘Natural products are among the most important sources of lead molecules for drug discovery.With the development of affordable whole-genome sequencing technologies and other‘omics tools,the field of natural products research is currently undergoing a shift in paradigms.While,for decades,mainly analytical and chemical methods gave access to this group of compounds,nowadays genomics-based methods offer complementary approaches to find,identify and characterize such molecules.This paradigm shift also resulted in a high demand for computational tools to assist researchers in their daily work.In this context,this review gives a summary of tools and databases that currently are available to mine,identify and characterize natural product biosynthesis pathways and their producers based on‘omics data.A web portal called Secondary Metabolite Bioinformatics Portal(SMBP at http://gffzz02e507a9d8884f08h60wqfvkpn6f56c0o.ffgz.tsg.suse.edu.cn)is introduced to provide a one-stop catalog and links to these bioinformatics resources.In addition,an outlook is presented how the existing tools and those to be developed will influence synthetic biology approaches in the natural products field.Tilmann Weber Hyun Uk Kim 2016Synthetic and Systems Biotechnology2016,1,2:10
18Current Status and Future Challenges of Weather Radar Polarimetry: Bridging the Gap between Radar Meteorology/Hydrology/Engineering and Numerical Weather Prediction显示文摘After decades of research and development, the WSR-88 D(NEXRAD) network in the United States was upgraded with dual-polarization capability, providing polarimetric radar data(PRD) that have the potential to improve weather observations,quantification, forecasting, and warnings. The weather radar networks in China and other countries are also being upgraded with dual-polarization capability. Now, with radar polarimetry technology having matured, and PRD available both nationally and globally, it is important to understand the current status and future challenges and opportunities. The potential impact of PRD has been limited by their oftentimes subjective and empirical use. More importantly, the community has not begun to regularly derive from PRD the state parameters, such as water mixing ratios and number concentrations, used in numerical weather prediction(NWP) models.In this review, we summarize the current status of weather radar polarimetry, discuss the issues and limitations of PRD usage, and explore potential approaches to more efficiently use PRD for quantitative precipitation estimation and forecasting based on statistical retrieval with physical constraints where prior information is used and observation error is included. This approach aligns the observation-based retrievals favored by the radar meteorology community with the model-based analysis of the NWP community. We also examine the challenges and opportunities of polarimetric phased array radar research and development for future weather observation.Guifu ZHANG Vivek N.MAHALE Bryan J.PUTNAM Youcun QI Qing CAO ANDrew D.BYRD Petar BUKOVCIC Dusan S.ZRNIC Jidong GAO Ming XUE Youngsun JUNG Heather D.REEVES Pamela L.HEINSELMAN AlexANDer RYZHKOV Robert D.PALMER Pengfei ZHANG Mark WEBER Greg M.MCFARQUHAR Berrien MOORE III Yan ZHANG Jian ZHANG J.VIVEKANANDAN Yasser AL-RASHID Richard L.ICE Daniel S.BERKOWITZ Chong-chi TONG Caleb FULTON Richard J.DOVIAK 2019Advances in Atmospheric Sciences2019,36,6:9
19Pretreatment neutrophil-to-lymphocyte ratio predicts worse survival outcomes and advanced tumor staging in patients undergoing radical cystectomy for bladder cancer显示文摘Objective:To determine the role of neutrophil-to-lymphocyte ratio(NLR)in prognosticating survival outcomes in patients with advanced/metastatic urothelial bladder cancer.Methods:We retrospectively reviewed 84 patients undergoing radical cystectomy(RC)for UCB from January 2002 to June 2012.NLR was computed(median:5 days)prior to surgery.No patients received neoadjuvant chemotherapy.NLR was analyzed as a continuous variable and a cut-off point of 2.7 was obtained,with a statistical receiver operating characteristics of 0.74.KaplaneMeier curves,multivariate Cox proportional hazard and logistics regression models were used to predict NLR association with survival outcomes.Results:The median follow-up period was 30.1 months(range:3.2e161.7)owing to high recurrence rate and subsequent mortalities,compared to the median 64.7 months in patients alive at the end of study period.NLR2.7 was associated with worse survival outcomes(5-year disease-specific survival:22%vs 58%,p Z 0.017,95%CI:1.193e6.009;5-year overall survival:23%vs 60%,p Z 0.008,95%CI:1.322e6.147).Furthermore,on multivariate analyses,higher NLR was independently associated with higher recurrence rate(p Z 0.007,HR Z6.999,95%CI:1.712e28.606),higher T staging(p Z 0.021,HR Z 3.479,95%CI:1.212e9.990)and lymph node involvement(p Z 0.009,HR Z 4.534,95%CI:1.465e14.034).Yu Guang Tan Ernest Eu Weber Lau Kam On Hong Hong Huang 2017Asian Journal of Urology2017,4,4:9
20上部地壳的流体作用与大理岩的低温塑性显示文摘本文应用光学显微镜、透射电子显微镜和阴极发光显微镜系统研究了 Waterberg断层带 (纳米比亚 )内粗晶大理岩中发育的构造岩。宏观碎裂结构与微观糜棱状结构是断层构造岩的主要特点。巨大的变形碎屑与弥漫的细小颗粒基质形成了鲜明的反差。广泛发育的压溶缝合线与多阶段方解石细脉遍布构造带不同部位。TEM亚微分析表明 ,细粒基质是由粗大碎屑经过亚颗粒旋转 ,并伴随着局部颗粒边界迁移形成的动态重结晶颗粒。虽然亚颗粒粒度具有简单的峰值分布 (~ 0 .3~0 .4μm) ,但动态重结晶颗粒的粒度却具有较大的变化范围 (0 .1~ 3.0μm )并具有多峰值分布的趋势。 TEM亚微结构 (晶格位错结构 )分析与亚颗粒、动态重结晶粒度、变形双晶宽度统计分析充分证明变形—恢复过程的非稳态特点。结合阴极发光分析阐明在上部地壳环境中 ,方解石大理岩经历脆性变形过程中 ,流体相广泛介入到变形作用中 ,并促进岩石的非稳态脆 -韧性转变与低温塑性的出现。刘俊来 Weber K Walter J 2000岩石学报2000,16,4:9
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