|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Robust adaptive cross-coupling position control of biaxial motion system显示文摘The stability and synchronous performance are usually hard to be improved simultaneously in the biaxial cross-coupling position motion control system.Based on analyzing the characteristics of the cross-coupling control system,a robust adaptive cross-coupling control strategy is proposed.To restrict influences of destabilizing factors and improve both of stability and synchronous performance,the strategy forces dual axes to track the same reference model using Narendra adaptive control theory.And then,a robust parameters adaptive law is proposed.The stability analysis of the proposed strategy is conducted by applying Lyapunov stability theory.Related simulations and experiments indicate that the proposed strategy can improve synchronous performance and stability simultaneously. | CHEN Wei WANG DianDian GENG Qiang XIA ChangLiang | 2016 | Science China(Technological Sciences)2016，59，4： | 12 |
| 2 | Comparison of the effects of two typesof multileaf collimators on tumor control probabilityin radiotherapy for breast cancer after conservativesurgery based on the EUD model显示文摘Objective To compute and compare the tumor control probability(TCP) of volumetric modulated arc therapy(VMAT) for breast cancer after conservative surgery based on two types of multileaf collimator(MLC) through a retrospective planning study.Methods For a group of 9 patients diagnosed with left breast cancer,VMAT plan based on Agility MLC and beam modulator(BM) MLC were designed.The prescription dose was 50 Gy covering at least 95% of the planning target volume,2 Gy per fraction.TCPs were calculated according to dose-volume histogram(DVH) analysis.Results The TCP of the BM VMAT plan was slightly higher than that of the Agility VMAT plan(94.61% vs 94.23%) but was inferior with respect to delivery efficiency;the delivery time was reduced for Agility VMAT plan by 35% compared to BM VMAT plan.Conclusion For breast cancer radiation therapy after conservative surgery,BM VMAT plans provide slightly higher TCP while the delivery of Agility VMAT plans is significantly faster than the BM VMAT plans. | Fuli Zhang Yadi Wang Weidong Xu Huayong Jiang Junmao Gao Qingzhi Liu Na Lu Diandian Chen Bo Yao Jun Hou Heliang He Jianping Chen | 2017 | Oncology and Translational Medicine2017，3，2： | 2 |
| 3 | Fabrication of Mo–Cu composites by a diffusion-rolling procedure显示文摘 | Yihang Yang Gaoyong Lin Xiaoying Wang Diandian Chen Aokui Sun Dezhi Wang | 2014 | International Journal of Refractory Metals and Hard Materials2014，，： | 1 |
| 4 | A dosimetric evaluation of flattening filter-free volumetric modulated arc therapy for postoperative treatment of cervical cancer显示文摘Objective The aim of the study was to compare flattening filter-free(FFF) beams and conventional flattening filter(FF) beams in volumetric modulated arc therapy(VMAT) for cervical cancer after surgery, through a retrospective planning study.Methods VMAT plans of FFF beams and normal FF beams were designed for a cohort of 15 patients. The prescribed dose was 45 Gy to 1.8 Gy per fraction, and at least 95% of the planning target volume received this dose. Doses were computed with a commercially available treatment planning system using a Monte Carlo(MC) algorithm. Plans were compared according to dose-volume histogram analysis in terms of planning target volume homogeneity and conformity indices(HI and CI), as well as organs at risk(OAR) dose and volume parameters. Results FFF-VMAT was similar to FF-VMAT in terms of CI, but inferior to FF-VMAT considering HI. No statistically differences were observed between FFF-VMAT and FF-VMAT in following organ at risks including pelvic bone marrow, small bowel, bladder, rectum, and normal tissue(NT)..Conclusion For patients with cervical cancer after hysterectomy, the FFF beam achieved target and OAR dose distribution similar to that of the FF beam. Reduction of beam-on time in cervical cancer is beneficial. | Fuli Zhang Huayong Jiang Weidong Xu Yadi Wang Junmao Gao Qingzhi Liu Ping Wang Na Lu Diandian Chen Bo Yao Jun Hou Heliang He Jianping Chen | 2016 | Oncology and Translational Medicine2016，2，4： | 1 |
| 5 | Automatic delineation of organs at risk in non-small cell lung cancer radiotherapy based on deep learning networks显示文摘Objective To introduce an end-to-end automatic segmentation method for organs at risk(OARs)in chest computed tomography(CT)images based on dense connection deep learning and to provide an accurate auto-segmentation model to reduce the workload on radiation oncologists.Methods CT images of 36 lung cancer cases were included in this study.Of these,27 cases were randomly selected as the training set,six cases as the validation set,and nine cases as the testing set.The left and right lungs,cord,and heart were auto-segmented,and the training time was set to approximately 5 h.The testing set was evaluated using geometric metrics including the Dice similarity coefficient(DSC),95%Hausdorff distance(HD95),and average surface distance(ASD).Thereafter,two sets of treatment plans were optimized based on manually contoured OARs and automatically contoured OARs,respectively.Dosimetric parameters including Dmax and Vx of the OARs were obtained and compared.Results The proposed model was superior to U-Net in terms of the DSC,HD95,and ASD,although there was no significant difference in the segmentation results yielded by both networks(P>0.05).Compared to manual segmentation,auto-segmentation significantly reduced the segmentation time by nearly 40.7%(P<0.05).Moreover,the differences in dose-volume parameters between the two sets of plans were not statistically significant(P>0.05).Conclusion The bilateral lung,cord,and heart could be accurately delineated using the DenseNet-based deep learning method.Thus,feature map reuse can be a novel approach to medical image auto-segmentation. | Anning Yang Na Lu Huayong Jiang Diandian Chen Yanjun Yu Yadi Wang Qiusheng Wang Fuli Zhang | 2022 | Oncology and Translational Medicine2022，8，2： | 1 |
| 6 | Dosimetric comparison of different multileaf collimators in volumetric modulated arc therapy for malignant pleural mesothelioma显示文摘Objective The aiom of the study was to compare the impacts of two types of multileaf collimators(MLC) [standard MLC with a width of 10 mm(s MLC) and micro-MLC with a width of 5 mm(m MLC)] on volumetric modulated arc therapy(VMAT) planning for malignant pleural mesothelioma. Methods VMAT for ten patients with inoperable malignant pleural mesotheliomas was retrospectively planned with the s MLC and m MLC. Histogram-based dose-volume parameters of the planning target volume(PTV) [conformity index(CI) and homogeneous index(HI)] and organs-at-risk were compared for VMAT plans with s MLC(s MLC-VMAT) and m MLC(m MLC-VMAT). Results The m MLC-VMAT plans were more efficient(average delivery time: 2.67±1.49 min) than the s MLC-VMAT plans(average delivery time: 4.21 ± 2.03 min; P < 0.05). Moreover, compared to the s MLC plans, the m MLC plans demonstrated advantages in the dose coverage of the PTV(CI 0.75 ± 0.08 vs 0.73 ± 0.09; HI 1.09 ± 0.02 vs 1.10 ± 0.02), although the difference was not statistically significant(P > 0.05). In addition, significant dose sparing in the fraction of the ipsilateral lung volume receiving > 20 Gy(V20; 54.72 ± 27.08 vs 58.52 ± 29.30) and > 30 Gy(V30; 42.74 ± 27.86 vs 46.86 ± 31.49) radiation, respectively, was observed for the m MLC plans(P < 0.05). Conclusion Comparing s MLC-VMAT and m MLC-VMAT not only demonstrated the higher efficiency and better optimal target coverage of m MLC-VMAT, but also considerably improved the dose sparing of the ipsilateral lung in the VMAT plans for malignant pleural mesothelioma. | Fuli Zhang Huayong Jiang Weidong Xu Yadi Wang Junmao Gao Qingzhi Liu Na Lu Diandian Chen Bo Yao Jun Hou Jianping Chen | 2015 | Oncology and Translational Medicine2015，1，4： | 0 |
| 7 | 两种四维CT重建算法对肺癌放疗靶区勾画影响的体模研究(英文)显示文摘Objective: The purpose of this study was to evaluate the performance of the phase-binning algorithm and amplitude-binning algorithm for four-dimensional computed tomography(4DCT) reconstruction in lung cancer radiation therapy. Methods: Quasar phantom data were used for evaluation. A phantom of known geometry was mounted on a four-dimensional(4D) motion platform programmed with twelve respiratory waves(twelve lung patients trajectories) and scanned with a Philips Brilliance Big bore 16-slice CT simulator. The 4DCT images were reconstructed using both phase- and amplitude-binning algorithms. Internal target volumes(ITVs) of the phase- and amplitude-binned image sets were compared by evaluation of shape and volume distortions. Results: The phantom experiments illustrated that, as expected, maximum inhalation occurred at the 0% amplitude and maximum exhalation occurred at the 50% amplitude of the amplitude-binned 4DCT image sets. The amplitude-binned algorithm rendered smaller ITV than the phase-binning algorithm. Conclusion: The amplitude-binning algorithm for 4DCT reconstruction may have a potential advantage in reducing the margin and protecting normal lung tissue from unnecessary irradiation. | Fuli Zhang Huayong Jiang Weidong Xu Yadi Wang Qingzhi Liu Na Lu Diandian Chen Bo Yao | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，12： | 0 |
| 8 | Dosimetric analysis of tomotherapy-based intensity-modulated radiotherapy with and without bone marrow sparing for the treatment of cervical cancer显示文摘Objective The aim of the study was to compare tomotherapy-based bone marrow-sparing intensity-modulated radiotherapy(BMS-IMRT) with intensity-modulated radiotherapy(IMRT) without entering the pelvic bone marrow as a planning constraint in the treatment of cervical cancer after hysterectomy. Methods BMS-IMRT and IMRT plans were designed for a cohort of nine patients. The prescribed dose was 45 Gy in 1.8 Gy daily fractions, and 95% of the planned target volume received this dose. The doses were computed using a commercially available treatment planning system with the convolution/superposition algorithm. Plans were compared according to dose-volume histogram analysis in terms of planning target volume homogeneity and conformity indices(HI and CI) as well as organ at risk dose and volume parameters. Results BMS-IMRT had advantages over IMRT in terms of CI, but was equivalent to the latter in HI. V5, V10, V20, V30, and V40 of pelvic bone marrow in BMS-IMRT decreased by 0.06%, 17.33%, 22.19%, 13.85%, and 16.46%, respectively, compared with IMRT. Except for V30 of the small bowel and V30 and V40 of the bladder, no statistically significant differences were found between BMS-IMRT and IMRT in the small bowel, bladder, and rectum. Conclusion For cervical cancer patients receiving tomotherapy-based radiotherapy after hysterectomy, BMS-IMRT reduced pelvic bone marrow volume receiving low-dose radiation, and it may be conducive to preventing acute hematologic toxicity. | Fuli Zhang Weidong Xu Huayong Jiang Yadi Wang Junmao Gao Qingzhi Liu Na Lu Diandian Chen Bo Yao Jianping Chen Heliang He | 2015 | Oncology and Translational Medicine2015，1，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员