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| 1 | Robust adaptive cross-coupling position control of biaxial motion system显示文摘The stability and synchronous performance are usually hard to be improved simultaneously in the biaxial cross-coupling position motion control system.Based on analyzing the characteristics of the cross-coupling control system,a robust adaptive cross-coupling control strategy is proposed.To restrict influences of destabilizing factors and improve both of stability and synchronous performance,the strategy forces dual axes to track the same reference model using Narendra adaptive control theory.And then,a robust parameters adaptive law is proposed.The stability analysis of the proposed strategy is conducted by applying Lyapunov stability theory.Related simulations and experiments indicate that the proposed strategy can improve synchronous performance and stability simultaneously. | CHEN Wei WANG DianDian GENG Qiang XIA ChangLiang | 2016 | Science China(Technological Sciences)2016，59，4： | 12 |
| 2 | Comparison of the effects of two typesof multileaf collimators on tumor control probabilityin radiotherapy for breast cancer after conservativesurgery based on the EUD model显示文摘Objective To compute and compare the tumor control probability(TCP) of volumetric modulated arc therapy(VMAT) for breast cancer after conservative surgery based on two types of multileaf collimator(MLC) through a retrospective planning study.Methods For a group of 9 patients diagnosed with left breast cancer,VMAT plan based on Agility MLC and beam modulator(BM) MLC were designed.The prescription dose was 50 Gy covering at least 95% of the planning target volume,2 Gy per fraction.TCPs were calculated according to dose-volume histogram(DVH) analysis.Results The TCP of the BM VMAT plan was slightly higher than that of the Agility VMAT plan(94.61% vs 94.23%) but was inferior with respect to delivery efficiency;the delivery time was reduced for Agility VMAT plan by 35% compared to BM VMAT plan.Conclusion For breast cancer radiation therapy after conservative surgery,BM VMAT plans provide slightly higher TCP while the delivery of Agility VMAT plans is significantly faster than the BM VMAT plans. | Fuli Zhang Yadi Wang Weidong Xu Huayong Jiang Junmao Gao Qingzhi Liu Na Lu Diandian Chen Bo Yao Jun Hou Heliang He Jianping Chen | 2017 | Oncology and Translational Medicine2017，3，2： | 2 |
| 3 | Fabrication of Mo–Cu composites by a diffusion-rolling procedure显示文摘 | Yihang Yang Gaoyong Lin Xiaoying Wang Diandian Chen Aokui Sun Dezhi Wang | 2014 | International Journal of Refractory Metals and Hard Materials2014，，： | 1 |
| 4 | Chromatographicngerprints and quantitative analysis of isoflavones in Tofu-type soybeans显示文摘 | Diandian S Qingli W Willian J S | 2012 | Bone2012，130，2： | 1 |
| 5 | A human ECG identifieation system based on ensemble empirical mode decomposition显示文摘 | Zhao Zhidong Yang Lei Chert Diandian | 2013 | Sensors2013，13，5： | 1 |
| 6 | A dosimetric evaluation of flattening filter-free volumetric modulated arc therapy for postoperative treatment of cervical cancer显示文摘Objective The aim of the study was to compare flattening filter-free(FFF) beams and conventional flattening filter(FF) beams in volumetric modulated arc therapy(VMAT) for cervical cancer after surgery, through a retrospective planning study.Methods VMAT plans of FFF beams and normal FF beams were designed for a cohort of 15 patients. The prescribed dose was 45 Gy to 1.8 Gy per fraction, and at least 95% of the planning target volume received this dose. Doses were computed with a commercially available treatment planning system using a Monte Carlo(MC) algorithm. Plans were compared according to dose-volume histogram analysis in terms of planning target volume homogeneity and conformity indices(HI and CI), as well as organs at risk(OAR) dose and volume parameters. Results FFF-VMAT was similar to FF-VMAT in terms of CI, but inferior to FF-VMAT considering HI. No statistically differences were observed between FFF-VMAT and FF-VMAT in following organ at risks including pelvic bone marrow, small bowel, bladder, rectum, and normal tissue(NT)..Conclusion For patients with cervical cancer after hysterectomy, the FFF beam achieved target and OAR dose distribution similar to that of the FF beam. Reduction of beam-on time in cervical cancer is beneficial. | Fuli Zhang Huayong Jiang Weidong Xu Yadi Wang Junmao Gao Qingzhi Liu Ping Wang Na Lu Diandian Chen Bo Yao Jun Hou Heliang He Jianping Chen | 2016 | Oncology and Translational Medicine2016，2，4： | 1 |
| 7 | Automatic delineation of organs at risk in non-small cell lung cancer radiotherapy based on deep learning networks显示文摘Objective To introduce an end-to-end automatic segmentation method for organs at risk(OARs)in chest computed tomography(CT)images based on dense connection deep learning and to provide an accurate auto-segmentation model to reduce the workload on radiation oncologists.Methods CT images of 36 lung cancer cases were included in this study.Of these,27 cases were randomly selected as the training set,six cases as the validation set,and nine cases as the testing set.The left and right lungs,cord,and heart were auto-segmented,and the training time was set to approximately 5 h.The testing set was evaluated using geometric metrics including the Dice similarity coefficient(DSC),95%Hausdorff distance(HD95),and average surface distance(ASD).Thereafter,two sets of treatment plans were optimized based on manually contoured OARs and automatically contoured OARs,respectively.Dosimetric parameters including Dmax and Vx of the OARs were obtained and compared.Results The proposed model was superior to U-Net in terms of the DSC,HD95,and ASD,although there was no significant difference in the segmentation results yielded by both networks(P>0.05).Compared to manual segmentation,auto-segmentation significantly reduced the segmentation time by nearly 40.7%(P<0.05).Moreover,the differences in dose-volume parameters between the two sets of plans were not statistically significant(P>0.05).Conclusion The bilateral lung,cord,and heart could be accurately delineated using the DenseNet-based deep learning method.Thus,feature map reuse can be a novel approach to medical image auto-segmentation. | Anning Yang Na Lu Huayong Jiang Diandian Chen Yanjun Yu Yadi Wang Qiusheng Wang Fuli Zhang | 2022 | Oncology and Translational Medicine2022，8，2： | 1 |
| 8 | 慧眼存真:美国费城艺术博物馆收藏的中国绘画显示文摘一九二九年美国费城艺术博物馆(the Philadelphia Museum of Art)的年度报告中,提及当地商人爱德华·罗比内特(Edward B.Robinette,公元一八八五~一九三六年)的慷慨捐赠,其中包含了三百余幅弗拉基米尔·格里高利维奇·西姆科维奇(Vladimir Gregorievitch Simkhovitch)收藏的中国古典绘画。报告中如此形容这批藏品:'或许除了波士顿美术馆。 | Li Diandian 呼格 | 2017 | 美成在久2017，，2： | 0 |
| 9 | Sn content gradient GeSn with strain controlled for high performance GeSn mid-infrared photodetectors显示文摘GeSn detectors have attracted a lot of attention for mid-infrared Si photonics,due to their compatibility with Si complementary metal oxide semiconductor technology.The GeSn bandgap can be affected by Sn composition and strain,which determines the working wavelength range of detectors.Applying the Sn content gradient GeSn layer structure,the strain of GeSn can be controlled from fully strained to completely relaxed.In this work,the strain evolution of GeSn alloys was investigated,and the effectiveness of gradually increasing Sn composition for the growth of high-Sn-content GeSn alloys was revealed.Relaxed GeSn thick films with Sn composition up to 16.3%were grown,and GeSn photodetectors were fabricated.At 77 K,the photodetectors showed a cutoff wavelength up to 4.2μm and a peak responsivity of 0.35 A/W under 1 V at 2.53μm.These results indicate that GeSn alloys grown on a Sn content gradient GeSn structure have promising application in mid-infrared detection. | XIANGQUAN LIU JUN ZHENG CHAOQUN NIU TAORAN LIU QINXING HUANG MINGMING LI DIANDIAN ZHANG YAQING PANG ZHI LIU YUHUA ZUO BUWEN CHENG | 2022 | Photonics Research2022，10，7： | 0 |
| 10 | Current progress of computational modeling for guiding clinical atrial fibrillation ablation显示文摘Atrial fibrillation(AF)is one of the most common arrhythmias,associated with high morbidity,mortality,and healthcare costs,and it places a significant burden on both individuals and society.Anti-arrhythmic drugs are the most commonly used strategy for treating AF.However,drug therapy faces challenges because of its limited efficacy and potential side effects.Catheter ablation is widely used as an alternative treatment for AF.Nevertheless,because the mechanism of AF is not fully understood,the recurrence rate after ablation remains high.In addition,the outcomes of ablation can vary significantly between medical institutions and patients,especially for persistent AF.Therefore,the issue of which ablation strategy is optimal is still far from settled.Computational modeling has the advantages of repeatable operation,low cost,freedom from risk,and complete control,and is a useful tool for not only predicting the results of different ablation strategies on the same model but also finding optimal personalized ablation targets for clinical reference and even guidance.This review summarizes three-dimensional computational modeling simulations of catheter ablation for AF,from the early-stage attempts such as Maze III or circumferential pulmonary vein isolation to the latest advances based on personalized substrate-guided ablation.Finally,we summarize current developments and challenges and provide our perspectives and suggestions for future directions. | Zhenghong WU Yunlong LIU Lv TONG Diandian DONG Dongdong DENG Ling XIA | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，10： | 0 |
| 11 | Dosimetric comparison of different multileaf collimators in volumetric modulated arc therapy for malignant pleural mesothelioma显示文摘Objective The aiom of the study was to compare the impacts of two types of multileaf collimators(MLC) [standard MLC with a width of 10 mm(s MLC) and micro-MLC with a width of 5 mm(m MLC)] on volumetric modulated arc therapy(VMAT) planning for malignant pleural mesothelioma. Methods VMAT for ten patients with inoperable malignant pleural mesotheliomas was retrospectively planned with the s MLC and m MLC. Histogram-based dose-volume parameters of the planning target volume(PTV) [conformity index(CI) and homogeneous index(HI)] and organs-at-risk were compared for VMAT plans with s MLC(s MLC-VMAT) and m MLC(m MLC-VMAT). Results The m MLC-VMAT plans were more efficient(average delivery time: 2.67±1.49 min) than the s MLC-VMAT plans(average delivery time: 4.21 ± 2.03 min; P < 0.05). Moreover, compared to the s MLC plans, the m MLC plans demonstrated advantages in the dose coverage of the PTV(CI 0.75 ± 0.08 vs 0.73 ± 0.09; HI 1.09 ± 0.02 vs 1.10 ± 0.02), although the difference was not statistically significant(P > 0.05). In addition, significant dose sparing in the fraction of the ipsilateral lung volume receiving > 20 Gy(V20; 54.72 ± 27.08 vs 58.52 ± 29.30) and > 30 Gy(V30; 42.74 ± 27.86 vs 46.86 ± 31.49) radiation, respectively, was observed for the m MLC plans(P < 0.05). Conclusion Comparing s MLC-VMAT and m MLC-VMAT not only demonstrated the higher efficiency and better optimal target coverage of m MLC-VMAT, but also considerably improved the dose sparing of the ipsilateral lung in the VMAT plans for malignant pleural mesothelioma. | Fuli Zhang Huayong Jiang Weidong Xu Yadi Wang Junmao Gao Qingzhi Liu Na Lu Diandian Chen Bo Yao Jun Hou Jianping Chen | 2015 | Oncology and Translational Medicine2015，1，4： | 0 |
| 12 | 两种四维CT重建算法对肺癌放疗靶区勾画影响的体模研究(英文)显示文摘Objective: The purpose of this study was to evaluate the performance of the phase-binning algorithm and amplitude-binning algorithm for four-dimensional computed tomography(4DCT) reconstruction in lung cancer radiation therapy. Methods: Quasar phantom data were used for evaluation. A phantom of known geometry was mounted on a four-dimensional(4D) motion platform programmed with twelve respiratory waves(twelve lung patients trajectories) and scanned with a Philips Brilliance Big bore 16-slice CT simulator. The 4DCT images were reconstructed using both phase- and amplitude-binning algorithms. Internal target volumes(ITVs) of the phase- and amplitude-binned image sets were compared by evaluation of shape and volume distortions. Results: The phantom experiments illustrated that, as expected, maximum inhalation occurred at the 0% amplitude and maximum exhalation occurred at the 50% amplitude of the amplitude-binned 4DCT image sets. The amplitude-binned algorithm rendered smaller ITV than the phase-binning algorithm. Conclusion: The amplitude-binning algorithm for 4DCT reconstruction may have a potential advantage in reducing the margin and protecting normal lung tissue from unnecessary irradiation. | Fuli Zhang Huayong Jiang Weidong Xu Yadi Wang Qingzhi Liu Na Lu Diandian Chen Bo Yao | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，12： | 0 |
| 13 | 吉姆·贾木许:似曾小小兴亡显示文摘当《李米的猜想》被部分影评人称为'今年最好的华语片'之后,质疑之声也不绝于耳。姑且不去论这个电影的好坏,熟悉吉姆.贾木许的人应该知道,周迅的扮相抄足了贾木许《地球之夜》中的一个片段。和薇诺拉.赖德一样,周迅白色大衬衣,烟不离手,还有电影开头两个同性恋坐在出租车后排表情怪异地缠绵,一模一样。当然,如果贾木许本人看到《李米的猜想》,大概也会一笑置之。因为贾木许阐述过他的创作黄金定律:'没有什么是真正的原创,从一切可能的地方偷来灵感,然后激发你自己的想象力。' | Diandian | 2009 | 东方电影2009，0，3： | 0 |
| 14 | Analytical and numerical simulations of uplift processes at the Tibet-Sichuan boundary显示文摘Previous studies have shown that the uplift of Tibetan plateau started in response to the collision of Indian plate and Eurasian plate. During this process, the crust of Tibetan plateau has been greatly thickened which leads to significant elevations. The elevation gradient is extremely large at the east boundary of Tibetan plateau where Longmenshan fault exists, dropping from 4500 to 500 m within a distance of100 km, while it is more gentle at the south and north sides of Sichuan basin. Such a difference of elevation gradient has been explained with a crustal channel flow model. However, previous crustal flow models consider the thickness of the lower crust as a constant which is highly simplified. Therefore, it is essential to build a more realistic crustal flow model, in which the thickness of the lower crust is variable and dependent on the inflow velocity of crustal materials. Here we build up both analytical and numerical models to study the mechanism and process of the uplift of Tibetan plateau at the eastern boundary.The results of the analytical model show that if the thickness of the lower crust can vary during the uplift process, the lower crustal viscosity of the Sichuan basin needs to be 1022 Pas to fit the observed elevation gradient. Such a viscosity is one-order magnitude larger than the previous results. Numerical model results further show that the state of stresses at the plateau boundary changes during uplift processes. Such a stress state change may cause the formation of different fault types in the Longmenshan fault area during its uplift history. | Diandian Peng Wei Leng | 2017 | Earthquake Science2017，30，3： | 0 |
| 15 | Dosimetric analysis of tomotherapy-based intensity-modulated radiotherapy with and without bone marrow sparing for the treatment of cervical cancer显示文摘Objective The aim of the study was to compare tomotherapy-based bone marrow-sparing intensity-modulated radiotherapy(BMS-IMRT) with intensity-modulated radiotherapy(IMRT) without entering the pelvic bone marrow as a planning constraint in the treatment of cervical cancer after hysterectomy. Methods BMS-IMRT and IMRT plans were designed for a cohort of nine patients. The prescribed dose was 45 Gy in 1.8 Gy daily fractions, and 95% of the planned target volume received this dose. The doses were computed using a commercially available treatment planning system with the convolution/superposition algorithm. Plans were compared according to dose-volume histogram analysis in terms of planning target volume homogeneity and conformity indices(HI and CI) as well as organ at risk dose and volume parameters. Results BMS-IMRT had advantages over IMRT in terms of CI, but was equivalent to the latter in HI. V5, V10, V20, V30, and V40 of pelvic bone marrow in BMS-IMRT decreased by 0.06%, 17.33%, 22.19%, 13.85%, and 16.46%, respectively, compared with IMRT. Except for V30 of the small bowel and V30 and V40 of the bladder, no statistically significant differences were found between BMS-IMRT and IMRT in the small bowel, bladder, and rectum. Conclusion For cervical cancer patients receiving tomotherapy-based radiotherapy after hysterectomy, BMS-IMRT reduced pelvic bone marrow volume receiving low-dose radiation, and it may be conducive to preventing acute hematologic toxicity. | Fuli Zhang Weidong Xu Huayong Jiang Yadi Wang Junmao Gao Qingzhi Liu Na Lu Diandian Chen Bo Yao Jianping Chen Heliang He | 2015 | Oncology and Translational Medicine2015，1，3： | 0 |
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