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| 1 | 慢性肾脏病中的炎症和动脉硬化:慢性肾功能不全队列研究中的发现显示文摘慢性肾脏病(chronic kidney disease,CKD)和动脉硬化程度与心血管病发病率和死亡率增加相关。目前认为炎症在动脉硬化发展中发挥作用,而CKD被认为是一种促炎症反应的状态。CKD患者的动脉僵硬度增加,横断面数据提示CKD中增多的炎症标志物与较高动脉僵硬度值相关。 | Peyster E Chen J Feldman HI Go AS Gupta J Mitra N Pan Q Porter A Rahman M Raj D Reilly M Wing MR Yang W Townsend RR 陈云 叶鹏 | 2017 | 中华高血压杂志2017，25，11： | 12 |
| 2 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 3 | 系统性药物治疗儿童银屑病的安全性显示文摘银屑病是一种常见的慢性炎症性皮肤病。成年人的发病率为2%~3%,其中大约有三分之一的患者在18岁之前发病。在儿童期,该病的发病率呈线性增长。从1970年至2000年,儿童银屑病的发病率增加了一倍多。尽管对许多轻度银屑病患儿而言,局部治疗已足够,但对更多可能影响生活质量的重度或顽固性的银屑病患儿,则往往需要系统性治疗。 | bronckers imgj seyger mmb west dp lara-corrales i tollefson m tom wl hogeling m belazarian l zachariae c mahé e siegfried e philipp s szalai z vleugels ra holland k murphy r baselga e cordoro k lambert j alexopoulos a mrowietz u kievit w paller as 邓婕(编译) 张锡宝(审校) 无 | 2017 | 皮肤性病诊疗学杂志2017，24，5： | 3 |
| 4 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 5 | Pharmacology of botulinum toxin显示文摘 | Huang W Foster JA Rogachefsky AS | 2000 | J Am Acad Dermatol2000，43，： | 2 |
| 6 | Effect of middle cerebral artery occlusion on the passage of pituitary adenylate cyclase activating polypeptide across the blood-brain barrier in the rat显示文摘 | Pan W Relglodi D | 2000 | Regul Peptide2000，91，： | 1 |
| 7 | Prediction of deleterious human alleles显示文摘 | Sunyaev S Ramensky V Koch I Lathe W 3rd Kondrashov AS Bork P | | 0，，： | 1 |
| 8 | Hepatitis B virus vari ants 显示文摘 | Chotiyaputta W Lok AS | 2009 | Nat Rev Gastroenterol I-lepatol2009，6，8： | 1 |
| 9 | Single-Site Laparoscopic Colorectal Surgery Provides Similar Clinical Outcomes Compared With Standard Laparoscopic Surgery : An Analysis of 626 Patients 显示文摘 | Sangster W Messaris E Berg AS | 2015 | Dis Colon Rectum2015，58，9： | 1 |
| 10 | Crofelemer, an antisecretory antidiarrheal proanthocyanidin oligomer extracted from Croton lechleri, targets two distinct intestinal chloride channels 显示文摘 | Tradtrantip L Namkung W Verkman AS | 2010 | Mol Pharmacol2010，77，1： | 1 |
| 11 | A clinical and polysomnographic comparison of neuroleptic-induced akathisia and the idiopathic restless legs syndrome显示文摘 | Walters AS Hening W Rubinstein M | 1991 | Sleep1991，14，4： | 1 |
| 12 | Ultrasound diagnosis of fetal lunge maturity显示文摘 | Sohn C Stolz W Gast AS | | 0，，02： | 1 |
| 13 | Novel function of complement C3d as an autologous helper T-cell target显示文摘 | Knopf PM Rivera DS Hai SH McMurry J Martin W De Groot AS | | 0，，03： | 1 |
| 14 | Population Pharmacokineticsof Dexmedetomidine in Critically 111 Patients 显示文摘 | Pyry AV Tuula AS Andrew W | 2013 | Clin Drug Investig2013，33，8： | 1 |
| 15 | Arson laser photocoagulation induced modification of gene expression in the retina 显示文摘 | Wilson AS Hobbs BG Shen W Y | 2003 | Invest Ophthalmol Vis Sci2003，44，： | 1 |
| 16 | Nitric oxide release by macrophages in respondse to particulate wear debris显示文摘 | Shanbhag AS Macaulay W Stefanovic-Racic M | 1998 | J Biomed Mater Res1998，41，3： | 1 |
| 17 | Science and technology for water purification in the coming decades显示文摘 | SHANNONL M A BOHN P W ELIMELECH M GEORGIADIS J G MARIAS B J MAYES A M | 2008 | Nature2008，452，3： | 1 |
| 18 | Attenuation of streptozotocin-induced microvascular changes in the mouse retina with the endothelin receptor A antagonist atrasentan显示文摘 | Wang Z Yadav AS Leskova W | 2010 | Exp Eye Res2010，91，： | 1 |
| 19 | In vitro Etest synergy of doripenem with amikacin, colistin, and levofloxacin against Pseudomonas aeruginosa with defined carbapenem resistance mechanisms as determined by the Etest method显示文摘 | He W Kaniga K Lynch AS | 2012 | Diagn Mi- crobiol Infect Dis2012，74，4： | 1 |
| 20 | Thyrotropin receptor epitopes and their relation to histoeompatibility leukocyte antigen- DR molecules in Graves' disease显示文摘 | Inaha H Martin W De Groot AS | 2006 | J Clin Endoerinol Metab2006，91，6： | 1 |
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