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| 1 | The cost of obsessive- compulsive disorder (OCD) in China: a multi- center cross- sectional survey based on hospitals显示文摘Background Obsessive-compulsive disorder(OCD)is considered a very debilitating disorder with severe loss of quality of life and income.Aims This study estimates the quality of life and economic consequences of OCD in China.Methods The research team interviewed 639 patients with OCD in 13 hospitals in 12 cities in China.The direct method was used to get the direct cost of OCD.Indirect costs associated with OCD were estimated using the human capital approach.Linear regression analysis was conducted for quality of life and generalised linear model analysis was conducted for total cost.Sensitivity analysis was used to analyse the uncertainty of total cost.Results The mean quality of life score for OCD was 52.78(20.46).The annual total cost of OCD per capita was 24503.78(95%CI:22621.53 to 26386.03)renminbi(RMB)(US$3465.88(95%CI:US$3199.65 to US$3732.11)).The annual cost of OCD in China was estimated to be 37.74 billion(95%CI:34.95 billion to 40.53 billion)RMB(equal to US$5.34 billion(95%CI:US$4.94 billion to US$5.73 billion)).Sensitivity analysis showed that the total annual cost of OCD in China was between 23.15 billion RMB(US$3.27 billion)and 370.00 billion RMB(US$52.33 billion).Worse social function status,more psychiatric symptoms and higher Yale Brown Obsessive-Compulsive Scale(Y-BOCS)score were associated with worse quality of life.The numbers of clinic visits and hospitalisations,socioeconomic status,education,Y-BOCS scores and age were found to be significantly associated with total cost.Conclusions OCD is associated with low quality of life and high costs in China.The findings call for concerted efforts to improve services for patients with OCD.Improvements may include early detection and diagnosis,the provision of evidence-based treatments and relapse prevention strategies. | Weili Yang Zhen Tang Xijin Wang Xiancang Ma Yuqi Cheng Bin Wang Ping Sun Wenxin Tang Jia Luo Changhong Wang Ping Li Guiyun Xu Jun Yan Vlasios Brakoulias Zhen Wang | 2021 | General Psychiatry2021，34，6： | 3 |
| 2 | Sulfur dioxide fumigation alone or in combination with CO 2-enriched atmosphere extends the market life of highbush blueberry fruit显示文摘 | Celia M Cantína Ioannis S Minasa Vlasios Goulas | | 0，，： | 1 |
| 3 | Sulfur dioxide fumigation alone or in combination with CO2 - enriched atmosphere extends the market life of highbush blueberry fruit显示文摘 | CELIA M C IOANNIS S M VLASIOS G | 2012 | Postharvest Biology and Technology2012，，67： | 1 |
| 4 | The Economic Growth Enigma: Capital, Labour and Useful Energy? 显示文摘 | Robert A Vlasios V | 2014 | Energy Policy2014，64，： | 1 |
| 5 | Sulfur dioxide fumiga- tion alone or in combination with C02-enriched atmosphere ex- tends the market life of highbush blueberry fruit 显示文摘 | Celia M C Ioannis S M Vlasios G | 2012 | Postharvest Biol Tec2012，67，： | 1 |
| 6 | Chemoembolization of Hepatocellular Carcinoma with Hepasphere 30–60 μm. Safety and Efficacy Study显示文摘 | Katerina Malagari Maria Pomoni Hippokratis Moschouris Alexios Kelekis Angelos Charokopakis Evanthia Bouma Themistoklis Spyridopoulos Achilles Chatziioannou Vlasios Sotirchos Theodoros Karampelas Constantin Tamvakopoulos Dimitrios Filippiadis Enangelos Kar | 2014 | CardioVascular and Interventional Radiology2014，，1： | 1 |
| 7 | Diagnostic subtyping of obsessive-compulsive disorder: Have we got it all wrong显示文摘 | Vlasios Brakoulias | 2012 | Australian & New Zealand Journal of Psychiatry2012，47，： | 1 |
| 8 | Psychic euosmia among obsessive-compulsive personality disorder patients:A case control study显示文摘BACKGROUND Psychic euosmia(PE)has been described as a supposed psychological predisposition for which pleasant smells elicit an immediate sense of pleasure,order and calmness in obsessive-compulsive personality disorder(OCPD).In this study we tried to verify the interpretation that PE is the counterpart of disgust that has been associated to contamination and moral purity.Disgust and morality are significantly associated in people with obsessive-compulsive personality traits.We expected that OCPD patients would experience higher levels of PE.AIM To investigate the PE frequency in OCPD patients and healthy controls(HC)and to evaluate the relationship between PE and disgust.METHODS A single-center,case-control study was conducted in an outpatient service for obsessive-compulsive and related disorders.The sample consisted of 129 subjects:45 OCPD patients and 84 HC.In both groups we submitted the Disgust Scale Revised(DS-R)and the self-report Structured Clinical Interview for DSM-5 Screening Personality Questionnaire to which we added an additional yes or no question to investigate the presence of PE.In order to verify differences between groups,t-test was employed for continuous variables and 2 test for categorical variable;odds ratio was employed to analyze group differences in the PE survey.Correlation was explored with Pearson r correlations.RESULTS No differences were observed between groups in gender composition or education.A slight significant difference was found in mean age(t=1.988;P=0.049).The present study revealed significantly higher proportions of PE among OCPD patients when compared to HC(OR:5.3,2.28-12.46).Patients with OCPD were more likely to report PE(n=36;80%)whereas a much lower proportion endorsed PE in the HC group(n=36;42.9%).Interestingly,no differences were observed between groups in mean score for the Disgust Scale.There was also no difference between the two groups in any of the Disgust Scale Revised subscales.Moreover,no significant correlations were observed in the OCPD group between PE and Disgust Scale Revised subscales.CONCLUSION Results suggested that PE might be part of the clinical spectrum of OCPD,and it does not reflect the counterpart of disgust.This could also indicate that this phenomenon is a manifestation of orderliness or incompleteness.Further studies will need to be undertaken to better understand PE and its significance in OCPD. | Annalisa Maraone Lorenzo Tarsitani Marianna Frascarelli Federica Petrini Valentina Roselli MassimilianoTinè Gabriele Cavaggioni Vlasios Brakoulias Massimo Biondi Massimo Pasquini | 2021 | World Journal of Psychiatry2021，11，2： | 0 |
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