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您的检索式：作者名="Victoria Cui"
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| 1 | Propofol Attenuates a-Synuclein Aggregation and Neuronal Damage in a Mouse Model of Ischemic Stroke显示文摘a-Synuclein is a soluble monomer abundant in the central nervous system. Aggregates of a-synuclein,consisting of higher-level oligomers and insoluble fibrils,have been observed in many chronic neurological diseases and are implicated in neurotoxicity and neurodegeneration.a-Synuclein has recently been shown to aggregate following acute ischemic stroke, exacerbating neuronal damage.Propofol is an intravenous anesthetic that is commonly used during intravascular embolectomy following acute ischemic stroke. While propofol has demonstrated neuroprotective properties following brain injury, the mechanism of protection in the setting of ischemic stroke is unclear. In this study, propofol administration significantly reduced the neurotoxic aggregation of a-synuclein, decreased the infarct area, and attenuated the neurological deficits after ischemic stroke in a mouse model. We then demonstrated that the propofol-induced reduction of a-synuclein aggregation was associated with increased mammalian target of rapamycin/ribosomal protein S6 kinase beta-1 signaling pathway activity and reduction of the excessive autophagy occurring after acute ischemic stroke. | Yuzhu Wang Dan Tian Changwei Wei Victoria Cui Huan Wang Yanbing Zhu Anshi Wu Yun Yue | 2020 | Neuroscience Bulletin2020，36，3： | 14 |
| 2 | Metal-organic frameworks based surface-enhanced Raman spectroscopy technique for ultra-sensitive biomedical trace detection显示文摘Metal-organic frameworks(MOFs)have attracted widespread interest due to their unique and unprecedented advantages in microstructures and properties.Besides,surface-enhanced Raman scattering(SERS)technology has also rapidly developed into a powerful fingerprint spectroscopic technique that can provide rapid,non-invasive,non-destructive,and ultra-sensitive detection,even down to single molecular level.Consequently,a considerable amount of researchers combined MOFs with the SERS technique to further improve the sensing performance and broaden the applications of SERS substrates.Herein,representative synthesis strategies of MOFs to fabricate SERS-active substrates are summarized and their applications in ultra-sensitive biomedical trace detection are also reviewed.Besides,relative barriers,advantages,disadvantages,future trends,and prospects are particularly discussed to give guidance to relevant researchers. | Yuna Zhang Cuili Xue Yuli Xu Shengsheng Cui Alexander A.Ganeev Kistenev Yury V Anna Gubal Victoria Chuchina Han Jin Daxiang Cui | 2023 | Nano Research2023，16，2： | 2 |
| 3 | Targeted Genome Modification in Mice Using Zinc-Finger Nucleases显示文摘 | Carbery Iara D Ji Diana Harrington Anne Brown Victoria Weinstein Edward J Liaw Lucy Cui Xiaoxia | 2010 | Genetics2010，，2： | 1 |
| 4 | 金属-有机配位聚合物:一种具有高效节能、高温冷却功能的先进的吸湿剂显示文摘一般来说,潜冷负荷占空调总负荷的30%,在许多热带和亚热带地区中所占的比例甚至更高。传统的蒸汽压缩式空调(VCAC)在除湿过程中制冷效率低,往往需要大量的后续再加热。传统的干燥剂或吸附剂控制室内湿度技术,由于再生温度高、循环时间长、元件体积大,竞争力甚至不如蒸汽压缩式空调。 | Shuqing Cui Menghao Qin Afsaneh Maran Victoria Steggles Sujing Wang Xiaoxiao Feng Farid Nouar Christian Serre | 2018 | 家电科技2018，0，12： | 0 |
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