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| 1 | Suicide ideation after the 1999 earthquake in Marmara,Turkey 显示文摘 | Vehid HE Alyanak B Eksi A | 2006 | Tohoku J Exp Med2006，208，1： | 1 |
| 2 | Potential effects of L-NAME on alcohol-induced oxidative stress显示文摘AIM: Nitric oxide (NO) is a highly reactive oxidant synthesized from L-arginine by nitric oxide synthase (NOS). NO may cause injury through the generation of potent radicals. Nwnitro-L-arginine methyl ester (L-NAME) is a non-selective inhibitor of NOS. We aimed to evaluate whether L-NAME treatment had protective effects against oxidative stress in rats intragastrically fed with ethanol during a 4 wk-period.METHODS: Thirty-six male Wistar rats were divided into 3 equal groups: group 1 (control group-isocaloric dextrose was given), group 2 (6 g/kg.d ethanol-induced group) and group 3 (both ethanol 6 g/kg.d and L-NAME 500 mg/L in drinking water-given group). Animals were sacrificed at the end of 4 wk-experimental period, and intracardiac blood and liver tissues were obtained. Biochemical measurements were performed both in plasma and in homogenized liver tissues. Alanine amino transferase (ALT), aspartate amino transferase (AST), malondialdehyde (MDA), NO, superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH) levels were measured by spectrophotometry.RESULTS: ALT and AST in group 2 (62 U/L and 128 U/L,respectively) were higher than those in group 1 (24 U/L and 38 U/L) and group 3 (37 U/L and 81 U/L) (P<0.001 for both).Plasma and tissue levels of MDA in group 2 (4.66 μmol/L and 0.55 nmol/mg protein) were higher than in group 1 (2.65 μmol/L and 0.34 nmol/mg protein) and group 3 (3.43 μmol/L and 0.36 nmol/mg protein) (P<0.001 for both). Plasma and liver tissue levels of NO in group 2 (54.67 μmol/L and 586.50 nmol/mg protein) were higher than in group 1 (34.67 μmol/L and 435.33 nmol/mg protein)and group 3 (27.50 μmol/L and 412.75 nmol/mg protein )(P<0.001 for both). Plasma and liver tissue SOD activities in group 2 (15.25 U/mL and 5.38 U/ mg protein,respectively) were lower than in group 1 (20.00 U/mL and 8.13 U/mg protein) and group 3 (19.00 U/mL and 6.93 U/mg protein) (P<0.001 for both). Plasma and liver tissue CAT activities in group 2 (145 U/mL and 37 U/ mg protein,respectively) were lower than in group 1 (176 U/mL and 73 U/mg protein) and group 3 (167 U/mL and 61 U/mg protein) (P<0.001 for both). Meanwhile, erythrocytes and liver tissue levels of GSH in group 2 (4.12 mg/g Hb and 5.38 nmol/mg protein, respectively) were lower than in group 1 (5.52 mg/g Hb and 4.49 nmol/mg protein) and group 3 (5.64 mg/g Hb and 4.18 nmol/mg protein) (P<0.001 for both).CONCLUSION: Our findings show that L-NAME may produce a restorative effect on ethanol-induced liver damage via decreasing oxidative stress and increasing antioxidant status. | Hafize Uzun Gonul Simsek Seval Aydin Ethem Unal Yesari Karter Nermin Karaturan Yelmen Suphi Vehid Asl Curgunlu Safiye Kaya | 2005 | World Journal of Gastroenterology2005，11，4： | 1 |
| 3 | Sol-gel based fabrication and characterization of new bioactive glass-ceramic composites for dental applications显示文摘 | Xanthippi Chatzistavrou Olga Tsigkou Harsh D Amin Konstantinos M Paraskevopoulos Vehid Salih Aldo R Boccaccini | | 0，，： | 1 |
| 4 | Suicide ideation after the 1999earthquake in Marmara,Turkey显示文摘 | Vehid H E Alyanak B Eksi A | 2006 | Tohoku J Exp Med2006，208，： | 1 |
| 5 | Suicide ideation after the 1999 earthquake in Marmara, Turkey 显示文摘 | Vehid HE Alyanak B Eksia KS | 2006 | Tohoku J ExpMed2006，208，1： | 1 |
| 6 | Suicide ideation after the 1999 earthquake in Marmara, Turkey 显示文摘 | VEHID H E ALYANAK B EKSI A | 2006 | Tohoku J Exp Med2006，208，1： | 1 |
| 7 | Suicide ideation after the 1999 earthquake in Marmara ,Turkey显示文摘 | Vehid H E Alyanak B Eksi A | 2006 | Tohoku J Exp Med2006，208，1： | 1 |
| 8 | Suicide ideation after the 1999 earthquake in Marmara, Turkey显示文摘 | Vehid H E Alyanak B Eksi A | 2006 | Tohoku J Exp Med2006，，1： | 1 |
| 9 | Stimulation of osteoblast responses to biomimetic nanocomposites of gelatin-hydroxyapatite for tissue engineering scaffolds显示文摘 | Hae-Wan Kin Hyoun-Ee Kim Vehid Salih | 2005 | Biomaterials2005，26，： | 1 |
| 10 | Elevated hair levels of cadmium and lead in school children ex- posed to smoking and in highways near schools 显示文摘 | Ttilin AySe Ozden Gtllbin Gfkcay Hayriye Vehid Ertem | 2007 | Clinical Bio- chemistry2007，40，： | 1 |
| 11 | Effects of ultrasound on the growth and function of bone and periodontal ligament cells in vitro显示文摘 | HARLE J VEHID S MAYIA F | 2001 | Ultrasound Med Biol2001，27，： | 1 |
| 12 | Osteochondral tissue engineering: scaffolds, stem cells and applications显示文摘 | Patcharakamon Nooeaid Vehid Salih Justus P. Beier Aldo R. Boccaccini | 2012 | J Cell Mol Med2012，，10： | 1 |
| 13 | Suicide ideation after the 1999 earthquakein Marmara,Turkey显示文摘 | Vehid HE Alyanak B Eksi A | 2006 | Tohoku J Exp Med2006，208，1： | 1 |
| 14 | Suicide ideation after the 1999 earthquake in Marmara, Turkey显示文摘 | Vehid H E Alyanak B Eksi A | 2006 | Tohoku J Exp Med2006，208，1： | 1 |
| 15 | Suicide Ideation after the 1999 Earthquake in Marmara, Turkey 显示文摘 | Vehid HE Alyanak B Eksi A | 2006 | Tohoku J Exp Med2006，208，1： | 1 |
| 16 | Comparison of nanoscale and microscale bioactive glass on the properties of P(3HB)/Bioglass&#reg; composites显示文摘 | Superb K M Dirk M Tobias J B Wendelin J S Sheryl E P Ipsita R Vehid S Jonathan C K Aldo R B | 2008 | Biomaterials2008，29，12： | 1 |
| 17 | Stimulation of osteoblast reponses to biomimetic nanocompostites of gelatin -hydroxyapatite for tissue engineering scaffolds 显示文摘 | Hae - Won Kiln Hyoun - Ee Kim Vehid Salih | 2005 | Biomaterials2005，26，： | 1 |
| 18 | 显示文摘 | Kim Hae-Won Kim Hyoun-Ee Salih Vehid | 2005 | Biomaterials2005，26，25： | 1 |
| 19 | Suicide ideation after the 1999 earth quake in Marmara,Turkey显示文摘 | Vehid HE Alyanak B Eksi A | 2006 | Tohoku J Exp Med2006，208，1： | 1 |
| 20 | Suicide ideation after the 1999 earthquake in Marmara,Turkey显示文摘 | Vehid HE Alyanak B Eksi A | 2006 | Tohoku J Exp Med2006，208，1： | 1 |
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