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20篇 您的检索式：作者名="Varchetta"

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	题名	作者	年代	出处	被引量
1	Chronic HIV-1 viremia reverses NKG2A/NKG2C ratio on natural killer cells in patients with human cytomegalovirus co-infection 显示文摘	Brunetta E Fogli M Varchetta S	2010	AIDS2010，24，1：	1
2	Natural killer cells in viral hepatitis: facts and controversies显示文摘	MONDELLI MU VARCHETTA S OLIVIERO B	2010	Eur J Clin Invest2010，40，9：	1
3	Natural killer cell dynamic profile is associated with treatment outcome in patients with chronic HCV infection<!-- Doctopic: VH -->显示文摘	Barbara Oliviero Dalila Mele Elisabetta Degasperi Alessio Aghemo Eleonora Cremonesi Maria Grazia Rumi Carmine Tinelli Stefania Varchetta Stefania Mantovani Massimo Colombo Mario U. Mondelli	2013	Journal of Hepatology2013，，1：	1
4	Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections显示文摘	Oliviero B Varchetta S Paudice E	2009	Gastroenterology2009，137，3：	1
5	Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections显示文摘	Oliviero B Varchetta S Paudice E	2009	Gastroenterology2009，137，3：	1
6	Unique immunological profile in patients with COVID-19显示文摘The relationship between severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)and host immunity is poorly understood.We performed an extensive analysis of immune responses in 32 patients with severe COVID-19,some of whom succumbed A control population of healthy subjects was included.Patients with COVID-19 had an altered distribution of peripheral blood lymphocytes,with an increased proportion of mature natural killer(NK)cells and low T-cell numbers.NK cells and CD8^(+)T cells overexpressed T-cellimmunoglobulin and mucin domain-3(TIM-3)and CD69.NK cell exhaustion was attested by increased frequencies of programmed cell death protein 1(PD-1)positive cells and reduced frequencies of natural killer group 2 member D(NKG2D)-,DNAX accessory molecule-1(DNAM-1)-and sialic acid-binding Ig-like lectin 7(Siglec-7)-expressing NK cells,associated with a reduced ability to secrete interferon(IFN)γ.Patients with poor outcome showed a contraction of immature CD56^(bright) and an expansion of mature CD57^(+)F_(CEI)Rlγ^(eng) adaptive NK cells compared to survivors.Increased serum levels of IL-6 were also more frequently identified in deceased patients compared to survivors.Of note,monocytes secreted abundant quantities of IL-6,IL-8,and IL-1β which persisted at lower levels several weeks after recovery with concomitant normalization of CD69,PD-1 and TIM-3 expression and restoration of CD8^(+)T cell numbers.A hyperactivated/exhausted immune response dominate in severe SARS-CoV-2 infection,probably driven by an uncontrolled secretion of inflammatory cytokines by monocytes.These findings unveil a unique immunological profile in COVID-19 patients that will help to design effective stage-specific treatments for this potentially deadly disease.	Stefania Varchetta Dalila Mele Barbara Olivier Stefania Mantovani Serena Ludovisi Antonella Cerino Raffaele Bruno Alberto Castelli Mario Mosconi Marco Vecchia Silvia Roda Michele Sachs Catherine Klersy Mario U.Mondelli	2021	Cellular & Molecular Immunology2021，18，3：	1
7	Natural killer cell func- tional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections 显示文摘	Oliviero B Varchetta S Paudiee E	2009	Gastroenterology2009，137，3：	1
8	Natural killer cells in viral hepatitis: factsandcontroversies显示文摘	Mondelli MU Varchetta S Oliviero B	2010	Eur J Clin Invest2010，40，9：	1
9	Natural killer cells in viral hepatitis: facts and controversies显示文摘	Mondelli M U Varchetta S Oliviero B	2010	Eur J Clin Invest2010，40，9：	1
10	Natural Killer Cell Functional Dichotomy in Chronic Hepatitis B and Chronic Hepatitis C Virus Infections显示文摘	Barbara Oliviero Stefania Varchetta Enrica Paudice Giuseppe Michelone Marco Zaramella Domenico Mavilio Francesca De Filippi Savino Bruno Mario U. Mondelli	2009	Gastroenterology2009，，3：	1
11	Chronic HIV-1viremia reverses NKG2A/NKG2Cratio on natural killer cells in patients with human cytomegalovirus co-infection显示文摘	Brunetta E Fogli M Varchetta S	2010	AIDS2010，24，1：	1
12	Natural killer ceils in viral hepatitis: facts and controversies显示文摘	Mondelli MU Varchetta S Oliviero B	2010	Eur J Clin Invest2010，40，9：	1
13	Enhanced B -cell differentiation and reduced proliferative capacity in chronichepatitis C and chronic hepatitis B virus infections显示文摘	OLIVIERO B CERINO A VARCHETTA S	2011	J Hepa-tol2011，55，1：	1
14	Elements related to heterogeneity of anti body-dependent cell cytotoxieity in patients under trastu zumab therapy for primary operable breast cancer overex pressing Her2显示文摘	Varchetta S	2007	Cancer Res2007，67，14：	1
15	Enhanced B-cell differentiation and reduced proliferative capacity in chronic hepatitis C and chronic hepatitis B virus infections显示文摘	Oliviero B Cerino A Varchetta S		0，，01：	1
16	Elements related to heterogeneity of antibody-dependent cell cytotoxicity in patients under trastuzumab therapy for primary operable breast cancer overexpressing Her2显示文摘	Varchetta S Gibelli N Oliviero B	2007	Cancer Res2007，67，11：	1
17	Low-dose prolonged intermittent interleukin-2adjuvant therapy:results of a randomized trial among human immunodeficiency virus-positive patients with advanced immune impairment显示文摘	Marchetti G Meroni L Varchetta S	2002	The Journal of infectious diseases2002，186，5：	1
18	Different combinations of cytokines and activating receptor stimuli are required for human natural killer cell functional diversity显示文摘	Varchetta S Oliviero B Mavilio D	2013	Cytokine2013，62，1：	1
19	Elements related to heterogeneity of antibody-dependent cell cytotoxicity in patients under trastuzumab therapy for primary operable breast cancer overexpressing Her2 显示文摘	VARCHETTA S GIBELLI N OLIVIERO B	2007	Cancer Res2007，67，11：	1
20	Enhanced B cell differentiation and reduced proliferative capacity in chronic hepatitis C and chronic hepatitis B virus infections显示文摘	Oliviero B Cerino A Varchetta S	2011	J Hepatol2011，55，7：	1

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