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| 1 | Burden of care in caregivers of patients with alcohol use disorder and schizophrenia and its association with anxiety, depression and quality of life显示文摘Background Caregivers play a pivotal role in providing care for mentally ill patients.Increase in caregiver burden can make them vulnerable to mental illness themselves.Aims We assessed the severity of burden of care and its association with depression,anxiety and quality of life among caregivers of patients with alcohol use disorder(AUD)and schizophrenia.Methods This was an observational,cross-sectional,single-centred study of 50 consecutive caregivers of patients with AUD and schizophrenia.Participants were recruited from the psychiatry outpatient department of a tertiary care hospital between January and June 2017.The caregivers were further assessed by demographic details,Hospital Anxiety Depression Scale for assessment of depression and anxiety,Zarit Burden Interview for assessment of caregiver burden and WHO Quality Of Life-BREF for assessment of quality of life.Statistical data were analysed using GraphPad InStat V.3.06(California).Multiple linear regression analysis was applied to identify the predictors of caregiver burden.Results Burden of care experienced by caregivers of patients with AUD is as high as that of caregivers of patients with schizophrenia(U=1142.5,p=0.46).Caregivers experiencing high burden of care are likely to have symptoms of anxiety(U=22,p<0.001),depression(U=32,p<0.001)and poor quality of life(U=84.5,p<0.001).Female caregivers are likely to experience higher burden of care(U=819.5,p=0.006).For caregivers of patients with schizophrenia,anxiety,environmental health,socioeconomic status and patients,occupation can predict burden of care,while for caregivers of patients with AUD,depression and environmental health can predict burden of care.Conclusion Our study suggests that caregivers of patients with AUD experience burden of care as high as that of caregivers of patients with schizophrenia.Caregivers with high burden of care are more likely to have depression,anxiety and poor quality of life.Trial registration number CTRI/2017/03/008224. | Sneha Vadher Rishi Desai Bharat Pancha Ashok Vala Imran Jahangirali Ratnani Mihir P Rupani Kinjal Vasava | 2020 | General Psychiatry2020，33，4： | 7 |
| 2 | Geometric theory of nonlocal two-qubit operations显示文摘 | Zhang J Vala J Sastry S | 2003 | Phys Rev A2003，67，04： | 1 |
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| 4 | Severe neonatal jaundice associated with glucose-6-phosphate dehydrogenase deficiency: pathogenesis and global epidemiology显示文摘 | Valaes T | 1994 | Acta Paediatr Suppl1994，394，： | 1 |
| 5 | Reversible formation of charge carrier traps on poly (phenylenevinylene) derivative due to the phototransformation of a photochromic additive 显示文摘 | Weiter M Vala M Salyk O | 2005 | Mol Cryst Liq Cryst2005，430，： | 1 |
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| 7 | Exact two-qubit universal quantum circuit显示文摘 | Zhang J Vala J Sastry S | 2003 | Phys Rev Lett2003，91，02： | 1 |
| 8 | An extended X-ray absorption fine structure spectroscopy investigation of cadmium sorption on cryptomelane显示文摘 | Randall Simon R Sherman David M Vala Ragnarsdottir K | 1998 | Chemical Geology1998，151，： | 1 |
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| 12 | The inhibitory leukocyte-associated Ig-like receptor-1 (LAIR-1) is expressed at high level by human naive T cells and inhibit TCR mediated activation显示文摘 | Maassho K Masilamani M Valas R | 2005 | Mol Immunol2005，42，12： | 1 |
| 13 | The inhibitory LAIR-1 is expressed at high levels by human naive T cells and inhibits TCR mediated activation 显示文摘 | Maasho K Masilamani M Valas R | 2005 | Mol Immunol2005，42，12： | 1 |
| 14 | The inhibitory leukocyte associated Ig like receptor-1 (LAIR-l) is expressed at high levels by human naive T ceils and inhibits TCR mediated activation显示文摘 | Maasho K Masilamani M Valas R | 2005 | Mol Immunol2005，42，12： | 1 |
| 15 | Tunability of waveguide modes in two-dimensional photonic crystals based on superconducting materials显示文摘 | Jamal Barvestani Emad Rezaei Ali Soltani Vala | 2013 | Optics Communications2013，，： | 1 |
| 16 | The role of haemolysis in neonatal hyperbilirubinaemia as reflected in carboxyhaemoglobin levels显示文摘 | Necheles TF Raj US Valaes T | 1976 | Acta Paediatr Scand1976，65，3： | 1 |
| 17 | Anti 2tumoracrivity ofinterferon-alpha in multiple myeloma:role of interleukin6 and tumor cell differentiation显示文摘 | Matsui M Huffc A Vala M | 2003 | Br J Haematol2003，121，8： | 1 |
| 18 | Diabetic Nephropathy Amelioration by a Low-Dose Sitagliptin in an Animal Model of Type 2 Diabetes (Zucker Diabetic Fatty Rat)显示文摘 | Cristina Mega Edite Teixeira de Lemos Helena Vala Rosa Fernandes Jorge Oliveira Filipa Mascarenhas-Melo Frederico Teixeira Flávio Reis Yoshio Shimizu | 2011 | Experimental Diabetes Research2011，，： | 1 |
| 19 | Correlation between erythrocyte CR reduction and other blood proteinase marker in patients with malignant and inflammatory disorders显示文摘 | CURRIE M S VALA M PISETSKY D S | 1990 | Blood1990，75，8： | 1 |
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