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| 1 | Alcohol dehydrogenase: A potential new marker for diagnosis of intestinal ischemia using rat as a model显示文摘AIM: Intestinal ischemia (Ii) is an abdominal emergency due to blockade of the superior mesenteric artery resulting in 60-100% mortality if diagnosed late. Changes in several biochemical parameters such as D (-)-lactate, Creatinine kinase isoenzymes and lactate dehydrogenase suggested for early diagnosis, lack specificity and sensitivity. Therefore a biochemical parameter with greater sensitivity needs to be identified.METHODS: Wistar male rats were randomly assigned into two groups; control sham operated (n = 24) and ischemic test (n = 24) group. Superior mesenteric arterial occlusion was performed in the ischemic test group for 1 h. Alcohol dehydrogenase (ADH) was estimated in blood from portal vein, right ventricle of heart, dorsal aorta (DA) and inferior vena cava (IVC). The Serum glutamic acid pyruvate transaminase (SGPT) was also estimated in blood from portal vein and right ventricle of heart.RESULTS: A significant increase (P<0.001) in the levels of ADH in both portal blood as well as heart blood of the test group (232.72±99.45 EU and 250.85±95.14 EU, respectively)as compared to the control group (46.39±21.69 EU and 65.38±30.55 EU, respectively) were observed. Similarly,increased levels of ADH were observed in blood samples withdrawn from DA and IVC in test animals (319.52±80.14EU and 363.90±120.68 EU, respectively) as compared to the control group (67.68±63.22 EU and 72.50±58.45 EU,respectively). However, in test animals there was significant increase in SGPT in portal blood (P = 0.054) without much increase in heart blood.CONCLUSION: Significant increase in the levels of ADH in portal and heart blood within 1 h of SMA occlusion without increase in SGPT in heart blood, suggests that the origin of ADH is from ischemic intestine and not from liver. Similarly, raised ADH levels were found in DA and IVC as well. IVC blood does represent peripheral blood sample. A raised level of ADH in test animals confirms it to be a potential marker in the early diagnosis of Ii. | Upendra R Gumaste Mukund M Joshi Devendra T Mourya Pradip V Barde Ghanshyam K Shrivastav Vikram S Ghole | 2005 | World Journal of Gastroenterology2005，11，6： | 9 |
| 2 | A saliency map based on sampling an image into random rectangular regions of interest 显示文摘 | Vikram T N Tscherepanow M Wrede B | 2012 | Pattern Recognition2012，45，9： | 1 |
| 3 | Immobilization of phenol in cement-based solidified/stabilized hazardous wastes using regenerated activated carbon: Leaching Studies显示文摘 | VIKRAM M HASSAN A HONG S | 1999 | J Hazard Mater1999，0，： | 1 |
| 4 | Catalytic behavior of Nickel Nanoparticles stabilized by lower alkylammonium bromide in aqueous medium显示文摘 | Singla M L Anjali N Vikram M | 2007 | Appl Catal A:Gen2007，323，： | 1 |
| 5 | A saliency map based on sampling an image into random rectangular regions of interest显示文摘 | VIKRAM T N TSCHEREPANOW M WREDE B | 2012 | Pattern Recognition2012，45，9： | 1 |
| 6 | Optimum design of power MOSFET's 显示文摘 | Hu Chenming Chi Min-Hwa Patel Vikram M | 1984 | IEEE Transactions on Electron Devices1984，31，12： | 1 |
| 7 | A Novel Wideband FMM for Fast Integral Eequation Solution of Multiscale Problems in Electromagnetics显示文摘 | Vikram M Huang H Shanker Band Van T | 2009 | IEEE Transactions on Antennas and Propagation2009，57，7： | 1 |
| 8 | Robust stabilization for systems with parametric uncertainty and time delay 显示文摘 | Vikram K Wassim M H | 1999 | J of the Franklin Institute1999，336，： | 1 |
| 9 | Liquidity,investment ability and mutual fund structure显示文摘 | Vikram N Narayanan M | 2000 | Journal of Financial Economics2000，，： | 1 |
| 10 | Extrapulmonary tuberculosis: an overview 显示文摘 | Golden M P Vikram HR | 2005 | Am Fam Physician2005，72，9： | 1 |
| 11 | Avian reovirus nonstructural protein μNS forms viroplasm-like inclusions and recruits protein σNS to these structures显示文摘 | Otero T F Costas M J Vikram V N | 2004 | Virology2004，319，1： | 1 |
| 12 | Low Fat Cheese Technology 显示文摘 | VIKRAM V M | 2001 | International Dairy Journal2001，11，7： | 1 |
| 13 | Simple anthropometric measures identify fasting hyperinsulinemia and clustering of cardiovascular risk factors in Asian Indian adolescents显示文摘 | Misra A Madhavan M Vikram NK | | 0，，12： | 1 |
| 14 | Low Fat Cheese Technology 显示文摘 | VIKRAM V M | 2001 | International Dairy Journal2001，，11： | 1 |
| 15 | Extrapulmonary tuberculosis : an overview 显示文摘 | Giden M P Vikram H R | 2005 | Am Fam Physician2005，72，： | 1 |
| 16 | Sonography of the Scrotum显示文摘 | VIKRAM S DOGRA M D RONALD H | 2003 | Radiology2003，227，： | 1 |
| 17 | Liquidity, investment ability, and mutual fund structure显示文摘 | Vikram N Narayanan M Warther V | 2000 | Journal of Financial Economics2000，57，41： | 1 |
| 18 | Optimum Design of Power MOSFETS显示文摘 | Hu Chenming Chi Min-Hwa Patel Vikram M | 1984 | IEEE Transactions on Electron Devices1984，31，12： | 1 |
| 19 | Liquidity,investment ability,and mutual fund structure显示文摘 | Narayanan M P | 2000 | Journal of Financial Economics2000，，57： | 1 |
| 20 | Optimum Design of Power MOSFET'S 显示文摘 | Chenming Hu Min-Hwa Chi Vikram M P | 1984 | IEEE Transactions on Electron Devices1984，31，12： | 1 |
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