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| 1 | Near-infrared fluorescence sentinel lymph node detection in gastric cancer: A pilot study显示文摘AIM: To investigate feasibility and accuracy of nearinfrared fluorescence imaging using indocyanine green: nanocolloid for sentinel lymph node(SLN) detection in gastric cancer.METHODS: A prospective, single-institution, phaseI feasibility trial was conducted. Patients suffering from gastric cancer and planned for gastrectomy were included. During surgery, a subserosal injection of 1.6 m L ICG:Nanocoll was administered around the tumor. NIR fluorescence imaging of the abdominal cavity was performed using the Mini-FLARE? NIR fluorescence imaging system. Lymphatic pathways and SLNs were visualized. Of every detected SLN, the corresponding lymph node station, signal-to-background ratio and histopathological diagnosis was determined. Patients underwent standard-of-care gastrectomy. Detected SLNs outside the standard dissection planes were also resected and evaluated.RESULTS: Twenty-six patients were enrolled. Four patients were excluded because distant metastases were found during surgery or due to technical failure of the injection. In 21 of the remaining 22 patients, at least 1 SLN was detected by NIR Fluorescence imaging(mean 3.1 SLNs; range 1-6). In 8 of the 21 patients, tumor-positive LNs were found. Overall accuracy of the technique was 90%(70%-99%; 95%CI), which decreased by higher p T-stage(100%, 100%, 100%, 90%, 0% for respectively Tx, T1, T2, T3, T4 tumors). All NIR-negative SLNs were completely effaced by tumor. Mean fluorescence signal-to-background ratio of SLNs was 4.4(range 1.4-19.8). In 8 of the 21 patients, SLNs outside the standard resection plane were identified, that contained malignant cells in 2 patients.CONCLUSION: This study shows successful use of ICG:Nanocoll as lymphatic tracer for SLN detection in gastric cancer. Moreover, tumor-containing LNs outside the standard dissection planes were identified. | Quirijn RJG Tummers Leonora SF Boogerd Wobbe O de Steur Floris PR Verbeek Martin C Boonstra Henricus JM Handgraaf John V Frangioni Cornelis JH van de Velde Henk H Hartgrink Alexander L Vahrmeijer | 2016 | World Journal of Gastroenterology2016，22，13： | 9 |
| 2 | Near-infrared fluorescence imaging of a solitary fibrous tumor of the pancreas using methylene blue显示文摘A 67-year-old female presented with unexplained abdominal pain. A contrast-enhanced computed tomography scan of the abdomen incidentally revealed a mass in the uncinate process of the pancreas. This mass was resected and based on histopathological findings, diagnosed as a solitary fibrous tumor (SFT) of the pancreas. A SFT is an extremely rare benign mesenchymal tumor that in 65% of cases affects the visceral pleura but can also affect extra-pleural sites. The intraoperative demarcation of pancreatic tumors, such as SFTs, can bechallenging. In this report, the first clear intraoperative identification of a SFT of the pancreas in a human was shown using near-infrared fluorescence and methylene blue. | Joost R van der Vorst Alexander L Vahrmeijer Merlijn Hutteman Tjalling Bosse Vincent THBM Smit Cornelis JH van de Velde John V Frangioni Bert A Bonsing | 2012 | World Journal of Gastrointestinal Surgery2012，4，7： | 7 |
| 3 | Nonlinear estimation with quan- tized measurements-PCM, predictive quantization, and data com- pression显示文摘 | Curry R Velde W V Potter J | 1970 | IEEE Trans on Information Theory1970，16，2： | 1 |
| 4 | Effects of formoterol (Oxis turbuhaler) and ipratopium on exercise capacity in patients with COPD显示文摘 | Liesker JJ De velde V Meysman M | 2002 | Respir Med2002，96，8： | 1 |
| 5 | Price limits in futures markets: effects on the price discovery process and volatility 显示文摘 | Yulia V Veld - Merkoulova | 2003 | International Review of Financial Analysis2003，12，： | 1 |
| 6 | Psychological contract breach and job attitudes:A meta-analysis of age as a moderator 显示文摘 | Bal P M De Lange A H Jansen P G W Der Velde M E G V | 2008 | Journal of Vocational Behavior2008，72，1： | 1 |
| 7 | The cps genes of Streptococcus suis serotype 1,2,and 9: development of rapid serotype-specific PCR assays显示文摘 | Smith HE Veenbergen V Velde JVD | 1999 | Clin Microbiol1999，37，10： | 1 |
| 8 | Police Message Diffu- sion on Twitter: Analysing the Reach of Social Media Communi- cations显示文摘 | Van De Velde B Meijer A Homburg V | 2015 | Behaviour & Information Technology2015，34，1： | 1 |
| 9 | The use of?uorescent dyes and probes in surgical oncolo-gy显示文摘 | TE VELDE E A VEERMAN T SUBRAMANIAM V etal | 2010 | EJSO2010，36，1： | 1 |
| 10 | Effects of inhaled ciclesonide and fluticasone propionate on cortisol secretion and airway responsiveness to adenosine 5'monophosphate in asthmatic patients显示文摘 | Derom E Van De Velde V Marissens S | 2005 | Pulm Pharmacol Ther2005，18，5： | 1 |
| 11 | Operations as marketing: a com-petitive services strategy显示文摘 | ROTH A VELDE V | 1991 | Journal of Operations Man- agement1991，10，3： | 1 |
| 12 | Boost- charging Li-ion batteries: a challenging new charging concept显示文摘 | Notten P H L Veld J H G O Beck J R G V | 2005 | Journal of Power Sources2005，145，1： | 1 |
| 13 | Methylated flavonols in Larrea euneifolia 显示文摘 | Valesi A G Rodriguez E Velde G V Mabry T J | 1972 | Phytochemistry1972，11，： | 1 |
| 14 | The prevalence and natural history of pituitary hemorrhage in prolactino- ma 显示文摘 | Sarwar KN /-Iuda MS Van de Velde V | 2013 | J Clin Endocrinol Metab2013，98，6： | 1 |
| 15 | A multicentre trial comparing different concentrations of ropivacaine plus sufentanil with bupivacaine plus sufentanil for patient-controlled epidural analgesia in labour显示文摘 | GOGARTEN W VAN DE VELDE V SOETENS F | 2004 | Eur J Anaesthesiol2004，21，： | 1 |
| 16 | Methylated favonols in Larrea cuneifolia显示文摘 | Valesi A G Rodriguez E Velde G V | | 0，，： | 1 |
| 17 | Optimum doses of deuterium oxide and sodium bromide for the determination of total body water and extracellular fluid 显示文摘 | Thomas L D Velde D V Schloeb P R | 1991 | J Pharm Biomed Analysis1991，9，58： | 1 |
| 18 | Effect of prucalopride on the pharmacolinetics of oral contraceptives in healthy women 显示文摘 | Velde V Vandeplassche L Hoppenbrousers M | 2013 | Drugs R D2013，13，1： | 1 |
| 19 | The effect of the tachykinin NK(2)receptor antagonist MEN11420(nepadutant)on neurokinin A-induced bronchoconstriction in asthmatics显示文摘 | Schelfhout V Van De Velde V Maggi C | | 0，，05： | 1 |
| 20 | Determination of Phenolie Compounds in Stawberries(Fragaria ananassa Duch) by High Performance Liquid Chromatography with Diode Array Detection显示文摘 | Tarola A M Velde F V Salvagni L | 2013 | Food Anal Methods2013，6，1： | 1 |
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