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498篇 您的检索式:作者名="VARGA Z"
    题名 作者 年代 出处 被引量
1Therapeutic proteasome inhibition in experimental acute pancreatitis显示文摘AIM: To establish the therapeutic potential of proteasome inhibition, we examined the therapeutic effects of MG132 (Z-Leu-Leu-Leu-aldehyde) in an experimental model of acute pancreatitis.METHODS: Pancreatitis was induced in rats by two hourly intraperitoneal (ip) injections of cholecystokinin octapeptide (CCK; 2 x 100 μg/kg) and the proteasome inhibitor MG132 (10 mg/kg ip) was administered 30 min after the second CCK injection. Animals were sacrificed 4 h after the first injection of CCK.RESULTS: Administering the proteasome inhibitor MG132 (at a dose of 10 mg/kg, ip) 90 min after the onset of pancreatic inflammation induced the expression of cell-protective 72 kDa heat shock protein (HSP72) and decreased DNA-binding of nuclear factor-kB (NF-kB). Furthermore MG132 treatment resulted in milder inflammatory response and cellular damage, as revealed by improved laboratory and histological parameters of pancreatitis and associated oxidative stress.CONCLUSION: Our findings suggest that proteasome inhibition might be beneficial not only for the prevention, but also for the therapy of acute pancreatitis.Tamás Letoha Liliána Z Fehér László Pecze Csaba Somlai Ilona Varga József Kaszaki Gábor Tóth Csaba Vizler László Tiszlavicz Tamás Takács 2007World Journal of Gastroenterology2007,13,33:5
2Geographic spillovers and university Research:a spatial econometric perspective 显示文摘ANSELIN L VARGA A ACS Z 2000Growth and Change2000,31,:1
3Ion channels and lymphocyte activation 显示文摘PANYI G VARGA Z GASPAR R 2004Immunol Lett2004,92,:1
4Study of humic-like substances in fog and interstitial aerosol by size-exclusion chromatography and capillary electrophoresis显示文摘Z Krivácsy Gy Kiss B Varga I Galambos Zs Sárvári A Gelencsér á Molnár S Fuzzi M.C Facchini S Zappoli A Andracchio T Alsberg H.C Hansson L Persson 2000Atmospheric Environment2000,,25:1
5Ochratoxin A in grapes and grape-derived products显示文摘Varga J Kozakiewicz Z 2006Trends in Food Science & Technology2006,17,:1
6Patents and innovation counts as measures of regional production of new knowledge 显示文摘Acs Z J Anselin L Varga A 2002Research Policy2002,31,7:1
7Comparison of differentiation pattern at allozyme and microsatellite loci in parnassius mnemosym population显示文摘Megleez E Pecsenge K Varga Z 1998Hereditas1998,128,:1
8Local Geographic Spillovers between University Research and High Technology InnoVations显示文摘Anselin L Varga A Acs Z 1997Journal of Urban Economics1997,42,3:1
9Ion channels and lymphocyte activation显示文摘Panyi G Varga Z Gaspar R 2004Immunol Lett2004,92,2:1
10Patents and Innovation Counts as Measures of Regional Produc- tion of New Knowledge显示文摘ACS Z J ANSELIN L VARGA A 2002Research Policy2002,31,7:1
11Extended pelvic Iymphadenectomy in patients undergoing radical prostatectomy:high incidence of lymph nodes metastasis 显示文摘Heidenreich A Varga Z yon Knobloch R 2002J Uro|2002,167,:1
12Local geography spillovers be- tween university research and high technology innovation 显示文摘Anselin L Varga A Acs Z 1997Journal of Urban Economics1997,42,3:1
13Chordoid glioma of the third ventricle:confirmatory report of a new entity显示文摘Vajtai I Varga Z Scheithauer BW et 81 1999Hum Pathol1999,30,6:1
14Identification of steroid sulfate transport processes in the human mammary gland显示文摘Pizzagalli F Varga Z Huber RD 2003J Clin Endocrinol Metab2003,88,15:1
15Complications of llizarov leg lengthening: a comparative study between patients with leg length dis- crepancy and short stature显示文摘Vargas Barreto B Caton J Merabet Z 2007Int Orthop2007,31,:1
16Patents and Innovation Counts as Measures of Regional Production of New Knowledge 显示文摘Acs Z Anselin L J Varga A 2002Research Policy2002,31,7:1
17Association between Novelty Seeking of opiate -dependent patients and the eatechol - O - methyltransferase Val (158) Met polymorphism 显示文摘Demetrovics Z Varga G Szekely A 2010Compr Psychiatry2010,51,5:1
18Complications of Ilizarov leg lengthening : a comparative study between patients with leg length dis- crepancy and short stature 显示文摘Vargas BB Caton J Merabet Z 2007lnt Orthop2007,31,:1
19Nephron-sparing surgery for renal angiomyolipoma显示文摘Heidenreich A Hegele A Varga Z 2002Eur Urol2002,41,3:1
20Local geographic spillovers between university research and high technology innovations 显示文摘Anselin L Varga A Acs Z 1997Journal of Urban Economics1997,42,:1
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