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852篇 您的检索式:作者名="VARGA G"
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1Therapeutic proteasome inhibition in experimental acute pancreatitis显示文摘AIM: To establish the therapeutic potential of proteasome inhibition, we examined the therapeutic effects of MG132 (Z-Leu-Leu-Leu-aldehyde) in an experimental model of acute pancreatitis.METHODS: Pancreatitis was induced in rats by two hourly intraperitoneal (ip) injections of cholecystokinin octapeptide (CCK; 2 x 100 μg/kg) and the proteasome inhibitor MG132 (10 mg/kg ip) was administered 30 min after the second CCK injection. Animals were sacrificed 4 h after the first injection of CCK.RESULTS: Administering the proteasome inhibitor MG132 (at a dose of 10 mg/kg, ip) 90 min after the onset of pancreatic inflammation induced the expression of cell-protective 72 kDa heat shock protein (HSP72) and decreased DNA-binding of nuclear factor-kB (NF-kB). Furthermore MG132 treatment resulted in milder inflammatory response and cellular damage, as revealed by improved laboratory and histological parameters of pancreatitis and associated oxidative stress.CONCLUSION: Our findings suggest that proteasome inhibition might be beneficial not only for the prevention, but also for the therapy of acute pancreatitis.Tamás Letoha Liliána Z Fehér László Pecze Csaba Somlai Ilona Varga József Kaszaki Gábor Tóth Csaba Vizler László Tiszlavicz Tamás Takács 2007World Journal of Gastroenterology2007,13,33:5
2Activating killer cell immunoglobulin-tike receptor genes' association with recurrent miscarriage显示文摘Vargas R G Bompeixe E P Franca P P 2009Am J Reprod Immunol2009,62,1:1
3Antioxidant and free radical scavenging activities of 5,7,3'-trihydroxy-3,6,4'-trimethoxyflavone from Brickellia veronicaefolia 显示文摘PF REZ G R M VARGAS S R MARTINEZ M F J 2004Phytother Res2004,18,5:1
4Microtensile bond strength of self-etching adhesives to ground and unground enamel显示文摘Ibarra G Vargas MA Armstrong SR 2002J Adhes Dent2002,4,2:1
5Residual solvents determination in pharmaceutical products by GC-HS and GCMS-SPME 显示文摘Camarasu C C Mezei-Szuts M Varga G B 1998J Pharm Biomed Anal1998,18,45:1
6Human renal cell carcinoma expresses distinct binding sites for growth hormone-releasing hor- mone显示文摘Halmos G Schally AV Varga JL 2000Proc Natl Acad Sci U S A2000,97,10:1
7Ion channels and lymphocyte activation 显示文摘PANYI G VARGA Z GASPAR R 2004Immunol Lett2004,92,:1
8Suppressors of cytokine signalin regulate angiotensin II-activated Janus kinase-signal transducers and activators of transcription pathway in renal cells显示文摘HEMANDEZ VARGAS P LOPEZ FRANCO O SANJUAN G 2005J Am Soc Nephrol2005,16,6:1
9Rotation and restricted use of antibiotics in medical intensive care unit显示文摘Gruson D Hilbert G Vargas F 2000Am J Respit Crit Care Med2000,162,3:1
10Chemical Composition and Biodegradability of Crop Residues Colonized by White-rot Fungi 显示文摘Karunanandaa K Fales S L Varga G A 1992J Sci Food Agric1992,60,:1
11Net absorption and oxygen consumption by Holstein steers fed alfalfa or orchard grass silage at two equalized intakes显示文摘Huntington G B Varga G A Ulenn B Y 1988J Anim Sci1988,6,:1
12Penaeid shrimp hemolymph lipoproteins 显示文摘Yepiz - Plascencia G Vargas - Mbores F Higuera - Ciapara I 2000Aquaculture2000,191,23:1
13Dendritic cells and tumor immunity显示文摘Gunzer M Janich S Varga G 2001Semin immunol2001,13,5:1
14The RT-based Concealed Information Test: An Overview of Current Research and Future Perspectives显示文摘Varga M Visu-Petra G Miclea M et ol 2014Procedia-Social and Behavioral Sciences2014,,127:1
15Bombesin receptor subtype mediation of gastroenteropancreatic hormone seere-tion in rats 显示文摘Varga G Adrian T E Coy D H 1994Peptides1994,15,4:1
16Opiine parasitoids (Hymenoptera: Braconidae) of oriental fruit fly (Diptera:Tephritidae) on Kauai island, Hawaii: islandwide relative abundance and parasitism rates in wild and orchards guava habitats显示文摘VARGAS R I SPARK J D UCHIDA G K 1993Environmetal Entomology1993,22,:1
17Role of complement in the pathomechanism of atherosclerotic vascular diseases显示文摘Szeplaki G Varga L Fast G 2009Mol Immunol2009,46,14:1
18Chemical and electrochemical basis of bioleaching processes 显示文摘HANSFORD G S VARGAS T 2001Hydrometallurgy2001,59,23:1
19Dendritic cells and tumor immunity semin显示文摘Gunzer M Janich S Varga G 2001Immunol2001,13,5:1
20Simulation for optimi- zing grain pattern on engineered grinding tools 显示文摘F W Pinto G E Vargas K Wegener 2008CIRP Annals - Manufacturing Technology2008,57,:1
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