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| 1 | Antibacterial activity and characterization of secondary metabolites isolated from mangrove plant Avicennia officinalis显示文摘Objective:To explore antibacterial activity and characterization of secondary metabolites isolated from mangrove plant Avicennia officinalis(A.officinalis).Methods:In the present study the leaf extracts of A.officinalis were examined for its antibacterial potential using five different solvents against some reference strains of human pathogenic bacteria for the crude extract.Maximum activity was observed for ethyl acetate and hence different concentrations like 15μL,25μL,and 50μL of ethyl extracts was checked for its antibacterial activity.Partial purification of crude extract was carried by column chromatography and fractions were analyzed using gas chromatography-mass spectrometry(GC-MS) to identify compounds.Results:The crude ethyl acetate extracts of A.officinalis showed remarkable antibacterial activity with zones of inhibition of 13 mm against Eschericia coli(E.coli) and 11 mm against Staphylococcus aureus (S.aureus).Fraction 13(ethyl acetate:methanol= 8:2) as the most potent one against with the minimal inhibitory concentration of 30 mm against E.coli and 25 mm against S.aureus.The GCMS resultsof active column fraction(F13) revealed that the active principals were a mixture of hydroxy- 4 methoxybenzoic acid,diethyl phthalate,oleic acid.Conclusions:The leaf extracts with proven antibacterial effects can clearly be directed towards cancer treatment as to inhibiting cancer cell growth.The limited number of test organisms owes to a constraint of resource.So,the effect of strong bursts of leaf extracts on human pathogenic bacteria should further be tested on a wide range of test organisms. | Valentin Bhimba B J Meenupriya Elsa Lycias Joel D Edaya Naveena Suman kumar M Thangaraj | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 13 |
| 2 | The effect of flutamide on the physical working capacity and activity of some of the key enzymes for the energy supply in adult rats显示文摘学习的目的是在老鼠为精力供应在一些关键肌肉酶的物理工作能力和活动上估计雄激素受体对手的效果。年轻成年男 Wistar 老鼠被划分成二个组。一个组一个星期和作为控制为服务 8 个星期的另外的组每天收到了 flutamide 的 15 mg kg-1 6 天。在开始并且在实验的结束,所有老鼠受到 submaximal 跑耐力(SRE ) ,疲劳(MTE ) 的最大的时间,和最大的疾跑速度(女士) 测试。在试用的结束,最大的氧消费(VO2max ) 测试被执行并且睾丸激素,红血球,血红素以及 succinate 脱氢酶(同步数字系列) 的酶活动的层次,喂奶脱氢酶(LDH ) ,和 gastrocnemius 肌肉的 NAD.H2-cytochrome-c reductase (NAD.H2 ) 被测量。对待 flutamide 的老鼠的浆液睾丸激素比控制的高,它验证选择的剂量的有效性。anti-androgen-treated 组的 MTE 和 SRE 与起始的价值相比是更低的。Flutamide 处理减少了同步数字系列和 NAD.H2 的活动与控制相比。我们没在女士, VO2max,跑的经济, LDH 活动,和 hematological 变量上发现反雄激素处理的效果。我们的调查结果显示象一些关键酶的活动一样的 submaximal 和最大的跑耐力的维护把氧化能力与肌肉联系了与雄激素效果被连接由雄激素受体调停了。 | Katerina N Georgieva Penka A Angelova Fani D Gerginska Dora D Terzieva Mihaela S Shishmanova-Doseva Slavi D Delchev Valentine V Vasilev | 2017 | Asian Journal of Andrology2017，19，4： | 2 |
| 3 | Antibacterial screening of silver nanoparticles synthesized by marine micro algae显示文摘Objective:To explore the biosynthesis of silver nanoparticles synthesized by marine microalgae. Methods:Marine microalgae was collected from Central Marine Fisheries Research Institute (CMFRI,tuticorin) and cultured in the lab.Silver nanoparticles synthesis were observed in normal and microwave irradiated microalgae and screened against human pathogens for the presence of antimicrobials.Results:The presence of silver nanoparticle was confirmed by UV-Visible spectroscopy at 420 nm by the presence of plasmon peak.Further confirmation was done by scanning electron microscope(SEM).Conclusions:These results not only provide a base for further research but are useful for drug development in the present and future. | D Devina Merin S Prakash B Valentine Bhimba | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，10： | 2 |
| 4 | Effect of culture conditions on microorganism identification by matrix-assisted laser desorption ionization mass spectrometry显示文摘 | Valentine N Wunschel S Wunschel D | | 0，，01： | 1 |
| 5 | Long term 15N studies in a catena of the shortgrass steppe显示文摘 | Delgado J A Mosier A R Valentine D W Schimel D S Parton W J | 1996 | Biogeochemistry1996，32，： | 1 |
| 6 | The specific diversity indices for analysing phytoplankton succession: application to the Cabo Frio (RJ, Brazil)upwelling ecosystem显示文摘 | VALENTIN J L MACEDO - SAIDAH F E TENENBAUM D R | 1991 | Neritica1991，6，： | 1 |
| 7 | The response of straight mobile bed hannels to inbank and overbank flows 显示文摘 | Knight D W Brown F A Valentine E M | 1999 | Proc Instn of Civil Engineers Water Maritime and Energy Division London1999，136，4： | 1 |
| 8 | Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial显示文摘 | Helen M Colhoun D John Betteridge Paul N Durrington Graham A Hitman H Andrew W Neil Shona J Livingstone Margaret J Thomason Michael I Mackness Valentine Charlton-Menys John H Fuller | 2004 | The Lancet . 2004 (9435)2004，，9435： | 1 |
| 9 | Highresolution three- dimensional micro - computed tomography detects bone loss and changes in trabecular architecture early: comparison with DEXA and bone histomorphometry in a rat model of disuse osteoporosis 显示文摘 | Barou O Valentin D Vico L | 2002 | Invest Radiol2002，37，1： | 1 |
| 10 | Fossils, molecules and embryos: new perspectives on the Cambrian explosion显示文摘 | Valentine JW Joblonski D Erwin DH | 1999 | Development1999，126，： | 1 |
| 11 | Connectionist models of face processing:a survey 显示文摘 | | 1994 | 27(9):1209-12301994，27，9： | 1 |
| 12 | Femtosecond Yb:YCOB laser pumped by narrow-stripe diode and passively mode locked using ion implanted saturable-absorber mirror 显示文摘 | VALENTINE G J KEMP A J B1RK1N D J L | 2000 | Electron Left2000，36，19： | 1 |
| 13 | Isotopic evidence for the incorporation of methane-derived carbon intoforaminifera from modern methane seeps, Hydrate Ridge, Northeast Paeific 显示文摘 | Hill T M Kenett J P Valentine D L | 2004 | Geochimica et Cosmochimica Acta2004，68，22： | 1 |
| 14 | Construction of a 41 kVA Bi/Y transformer显示文摘 | Tixador P Valentin G D Maher E | 2003 | IEEE Transactions on Applied Superconductivity2003，13，2： | 1 |
| 15 | Methane and Nitrous Oxide Fluxes in Native,Fertilized and Cultivated Grasslands显示文摘 | MOSIER A SCHIMEL D VALENTINE D | 1991 | Nature1991，350，6316： | 1 |
| 16 | Origin of the different photoaetivity of N-doped anatase and rutile TiO2 显示文摘 | VALENTIN C D PACCHIONI G SELLONI A | 2004 | Physical Review B2004，70，08： | 1 |
| 17 | Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells显示文摘 | Leslie Hodges-Gallagher Cathleen D Valentine Suzy El Bader | 2008 | Breast Cancer Res Treat2008，109，： | 1 |
| 18 | Methane and nitrous oxide fluxes in native fertilized and cultivated grass lands 显示文摘 | Mosier AR Schimel DS Valentine D eta! | 1994 | Nature1994，26，2： | 1 |
| 19 | Connection is models of faee processing 显示文摘 | VALENTIN D ABDI H O'TOOLE A J | 1994 | Pattern Recognition1994，27，： | 1 |
| 20 | Measles virus interaction with host cells and impact on innate immunity 显示文摘 | Gerlier D Valentin H | 2009 | Curt Top Mierobiol Immunol2009，329，1： | 1 |
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