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| 1 | Device-associated infection rates, mortality, length of stay and bacterial resistance in intensive care units in Ecuador: International Nosocomial Infection Control Consortium's findings显示文摘AIM To report the results of the International Nosocomial Infection Control Consortium(INICC) study conducted in Quito, Ecuador.METHODS A device-associated healthcare-acquired infection(DAHAI) prospective surveillance study conducted from October 2013 to January 2015 in 2 adult intensive care units(ICUs) from 2 hospitals using the United States Centers for Disease Control/National Healthcare Safety Network(CDC/NHSN) definitions and INICC methods. RESULTS We followed 776 ICU patients for 4818 bed-days. The central line-associated bloodstream infection(CLABSI) rate was 6.5 per 1000 central line(CL)-days, the ventilator-associated pneumonia(VAP) rate was 44.3 per 1000 mechanical ventilator(MV)-days, and the catheterassociated urinary tract infection(CAUTI) rate was 5.7 per 1000 urinary catheter(UC)-days. CLABSI and CAUTI rates in our ICUs were similar to INICC rates [4.9(CLABSI) and 5.3(CAUTI)] and higher than NHSN rates [0.8(CLABSI) and 1.3(CAUTI)]- although device use ratios for CL and UC were higher than INICC and CDC/NSHN's ratios. By contrast, despite the VAP rate was higher than INICC(16.5) and NHSN's rates(1.1), MV DUR was lower in our ICUs. Resistance of A. baumannii to imipenem and meropenem was 75.0%, and of Pseudomonas aeruginosa to ciprofloxacin and piperacillin-tazobactam was higher than 72.7%, all them higher than CDC/NHSN rates. Excess length of stay was 7.4 d for patients with CLABSI, 4.8 for patients with VAP and 9.2 for patients CAUTI. Excess crude mortality in ICUs was 30.9% for CLABSI, 14.5% for VAP and 17.6% for CAUTI. CONCLUSION DA-HAI rates in our ICUs from Ecuador are higher than United States CDC/NSHN rates and similar to INICC international rates. | Estuardo Salgado Yepez Maria M Bovera Victor D Rosenthal Hugo A González Flores Leonardo Pazmino Francisco Valencia Nelly Alquinga Vanessa Ramirez Edgar Jara Miguel Lascano Veronica Delgado Cristian Cevallos Gasdali Santacruz Cristian Pelaéz Celso Zaruma Diego Barahona Pinto | 2017 | World Journal of Biological Chemistry2017，8，1： | 23 |
| 2 | Stem cell therapy in the management of shoulder rotator cuff disorders显示文摘Rotator cuff tears are frequent shoulder problems that are usually dealt with surgical repair. Despite improved surgical techniques, the tendon-to-bone healing rate is unsatisfactory due to difficulties in restoring the delicate transitional tissue between bone and tendon. It is essential to understand the molecular mechanisms that determine this failure. The study of the molecular environment during embryogenesis and during normal healing after injury is key in devising strategies to get a successful repair. Mesenchymal stem cells(MSC) can differentiate into different mesodermal tissues and have a strong paracrine, anti-inflammatory, immunoregulatory and angiogenic potential. Stem cell therapy is thus a potentially effective therapy to enhance rotator cuff healing. Promising results have been reported with the use of autologous MSC of different origins in animal studies: they have shown to have better healing properties, increasing the amount of fibrocartilage formation and improving the orientation of fibrocartilage fibers with less immunologic response and reduced lymphocyte infiltration. All these changes lead to an increase in biomechanical strength. However, animal research is still inconclusive and more experimental studies are needed before human application. Future directions include expanded stem cell therapy in combination with growth factors or different scaffolds as well as new stem cell types and gene therapy. | Maria Valencia Mora Miguel A Ruiz Ibán Jorge Díaz Heredia Raul Barco Laakso Ricardo Cuéllar Mariano García Arranz | 2015 | World Journal of Stem Cells2015，7，4： | 6 |
| 3 | Parallel Implementation of Endmember Extraction Algorithms from Hyperspectral Data显示文摘 | Plaza A Valencia D Plaza J | 2006 | IEEE Transactions on Geoscience and Remote Sensing Letters2006，3，3： | 1 |
| 4 | Intrinsic errors in genome annotation显示文摘 | Devos D Valencia A | 2001 | Trends Genet2001，17，8： | 1 |
| 5 | Pea protein as a substi- tute of soya bean protein in diets for young pigs:Effects on productivity and digestive traits显示文摘 | Valencia D G Serrano M P Centeno C L | 2008 | Livestock Science2008，118，： | 1 |
| 6 | Phosphate immobilization using an acidic type F fly ash显示文摘 | Grubb D G Guimaraes M S Valencia R | 2000 | Journal of Hazardous Materials2000，76，23： | 1 |
| 7 | BRICHOS:a conserved domain in proteins associated with dementia,respiratory distress and cancer显示文摘 | Sánchez-Pulido L Devos D Valencia A | 2002 | Trends Biochem Sci2002，27，7： | 1 |
| 8 | Influence of sex and terminal sire line on performance and carcass and meat quality of Iberian pigs reared under intensive production systems 显示文摘 | Serrano M P Valencia D G Nieto M | 2008 | Meat Science2008，，78： | 1 |
| 9 | Vagus nerve stimulation in pediatric epilepsy:a review显示文摘 | Valencia I Holder D L Helmers S L | | 0，，05： | 1 |
| 10 | OWLPath: An OWL Ontology - Guided Query Editor显示文摘 | VALENCIA G R SANCHEZ F G CASTELLANOS N D | 2011 | IEEE Transactions on Systems Man and Cybernetics PartA: Systems and Humans2011，41，1： | 1 |
| 11 | CoMo/SBA- 15 catalysts prepared with EDTA and citric acid and their performance in hydrodesulfurization of dibenzothiophene 显示文摘 | PETA L VALENCIA D KLIMOVA T | 2014 | Applied Catalysis B: Environmental2014，147，： | 1 |
| 12 | BPdCHOS: a conserved domain in proteins associated with dementia, respiratory distress and cancer 显示文摘 | SANCHEZ-PUHDO L DEVOS D VALENCIA A | 2002 | Trends Biochem Sci2002，27，7： | 1 |
| 13 | Screening for trisomies 21,18 and 13 by maternal age,fetal nuchal translucency,fetal heart rate,free beta-hCG and pregnancy-associated plasma protein-A显示文摘 | Kagan KO Wright D Valencia C | | 0，，09： | 1 |
| 14 | Using DDM asymmetry metrics for wind direction retrieval from GPS ocean-scattered signals in airborne experiments显示文摘 | Valencia E Zavorotny V U Akos D M | 2014 | IEEE Transactions on Geoscience and Remote Sensing2014，52，7： | 1 |
| 15 | In- fluence of micronization (fine grinding) of soya bean meal and full fat soya bean on productive performance and digestive traits in young pigs 显示文摘 | D G Valencia M P Serrano R Lazaro M A | 2008 | Animal Feed Sci- ence and Technology2008，，147： | 1 |
| 16 | Distribution of c-reaction protein and its relation to risk factors and coronary heart disease risk estimation in the National Health and Nutrion Examination Survey (NHANES)Ⅲ 显示文摘 | WANG N D PIS J VALENCIA R | 2001 | Prey Cardiol2001，4，： | 1 |
| 17 | Commodity cluster-based parallel processing of hyperspectral imagery 显示文摘 | Plaza A Valencia D Plaza J | 2006 | Journal of Parallel Distributed Computing2006，66，： | 1 |
| 18 | Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?显示文摘 | Carlos Eugênio Cavasini Luiz Carlos de Mattos álvaro Augusto D'Almeida Couto Cláudia Regina Bonini-Domingos Socrates Herrera Valencia Wanessa Christina de Souza Neiras Renata Tomé Alves Andréa Regina Baptista Rossit Lilian Castilho Ricardo Luiz Dantas Mac | 2007 | Transactions of the Royal Society of Tropical Medicine and Hygiene2007，，10： | 1 |
| 19 | Functional traits and niche-based tree community assembly in an Amazonian forest 显示文摘 | Kraft N J B Valencia Renato Ackerly D D | 2008 | Science2008，322，： | 1 |
| 20 | Ef ect of main cereal of the diet and particle size of the cereal on productive performance and egg quality of brown egg-laying hens in early phase of production显示文摘 | Safaa H M Jiménez-Moreno E Valencia D G | | 0，，03： | 1 |
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