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49篇 您的检索式:作者名="Uslu C"
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1Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension显示文摘AIM:Adrenomedullin (ADM) is a potent vasodilator peptide.ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown, plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.METHODS: There were 4 groups of subjects. Group 1consisted of 27 patients (F/M: 12/15) with NCPH due to portal and/or splenic vein thrombosis (mean age: 41±12years), group 2 consisted of 14 patients (F/M: 6/8) with compensated (Child-Pugh A) cirrhosis (mean age: 46±4),group 3 consisted of 16 patients (F/M: 6/10) with decompensated (Child-Pugh C) cirrhosis (mean age: 47±12).Fourteen healthy subjects (F/M: 6/8) (mean age: 44±8) were used as controls in Group 4. ADM level was measured by ELISA. NO was determined as nitrite/nitrate level by chemoluminescence.RESULTS: Adl level in Group 11 (236±61.4 pg/mL) was significantly higher than that in group 2 (108.4±28.3 pg/mL)and group 4 (84.1±31.5 pg/mL) (both P<0.0001) but was lower than that in Group3 (324±93.7 pg/mL) (P=0.002). NO level in group 1 (27±1.4 μmol/L) was significantly higher than that in group 2 (19.8±2.8 μmol/L) and group 4 (16.9±1.6μmol/L) but was lower than that in Group 3 (39±3.6 μmol/L)(for all three P<0.0001). A strong correlation was observed between ADM and NO levels (r=0.827, P<0.0001).CONCLUSION: Adrenomedullin and NO levels were high in both non-cirrhotic and cirrhotic portal hypertension and were closely correlated, Adrenomedullin and NO levels increased proportionally with the severity of cirrhosis, and were significantly higher than those in patients with NCPH.Portal hypertension plays an important role in the increase of ADM and NO. Parenchymal damage in cirrhosis may contribute to the increase in these parameters.V Tahan E Avsar C Karaca E Uslu F Eren S Aydin H Uzun HO Hamzaoglu F Besisik C Kalayci A Okten N Tozun 2003World Journal of Gastroenterology2003,9,10:5
2Levels of soluble intercellular adhesion molecule-land total sialic acid in serum of patients with laryngeal cancer 显示文摘Akca YF Taysi S Uslu C 2001Jpn J Clin Oncol2001,31,12:1
3Arsenic trioxide-mediated cytotoxicity and apoptosis in proatate and ovarian carcinoma cell lines显示文摘 Sanli U A Ezgin C 2000Clin Cancer Res2000,6,12:1
4Arsenic trioxide-mediated cytotoxicity and apoptosis in proatate and ovarian carcinoma cell lines显示文摘USLU R SANLI UA SEZGIN C 2000Clin Cancer Res2000,6,12:1
5L-Cysteine influx and efflux: a possible role for red blood cells in regulation ofredox status of the plasma显示文摘Yildiz D Uslu C Cakir Y 2006Free Rad Res2006,40,5:1
6Arsenic trioxide-mediated cytotoxicity and apoptosis in proatate and ovarian carcinoma cell lines 显示文摘Uslu R Sanli UA Sezgin C 2000Clin Cancer Res2000,6,12:1
7Serum free and bound sialic acid and alpha-l-acid glycoprotein in patient with laryngeals cancer显示文摘Uslu C Taysi S Akcay F 2003Ann Clin Lab Sci2003,33,2:1
8Gemcitabine treatment in patients with inoperable locally advanced/metastatic pancreatic cancer and prognostic factors显示文摘SEZGIN C KARABULUT B USLU R 2005Scand J Gastroenterol2005,40,12:1
9Serum free and bound sialic acid and alpha-1-acid glycoprotein in patients with laryngeal cancer显示文摘Uslu C Taysi S Akcay F 0,,2:1
10Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines显示文摘Uslu R Sanli UA Sezgin C 2000Clin Cancer Res2000,6,:1
11Nitric oxide synthase activity and nitric oxide level in erythrocytes of guinea pigs with experimental otitis media with effusion显示文摘Yilmaz A Uslu C Akyuz M 2006Cell Biochem Funct2006,24,5:1
12Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines显示文摘Uslu R Sanli U A Sezgin C et ad 2000Clin Cancer Res2000,6,:1
13Levels of soluble intercellular adhesion molecule-land total sialie acid in serum of patients with laryngeal cancer显示文摘Akca YF Taysi S Uslu C 2001Jpn J Clin Oncol2001,31,12:1
14Nasal mucociliary clearance in total laryngectomized patients显示文摘Deniz M Uslu C Ogredik EA 2006Eur Arch Otorhinolaryngol2006,263,12:1
15Audiological and graft take results of cartilage reinforcement tympanoplasty (a new technique) versus fascia显示文摘Tek A Karaman M Uslu C 2012Eur Arch Otorhinolaryngol2012,269,:1
16The effects of obstructive sleep apnea syndrome due to adenotonsillar hypertrophy on the cardiovascular system in children显示文摘Tatlipinar A Duman D Uslu C 2011Turk J Pediatr2011,53,4:1
17Extracorporeal shockwave increases the effectiveness of systemic antibiotic treatment in implant-relatedchronic osteomyelitis:experimental study in a rat model显示文摘Inanmaz ME Uslu M Isik C 2014J Orthop Res2014,32,6:1
18Serum free and bound sialic acid and alpha-1-acid glycoprotein in patients with laryngeal cancer显示文摘Uslu C Taysi S Akcay F 2003Ann Clin Lab Sci2003,33,2:1
19Nitric oxide synthase activ-ity and nitric oxide level in erythrocytes of guinea pigs with ex-perimental otitis media with effusion显示文摘Yilmazl A Uslu C? Akyuz M 2006Cell Biochem Funct2006,24,5:1
20Which technique is better for cholesteatoma surgery显示文摘Deniz M Uslu C Kolda C 2015B-ENT2015,11,2:1
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