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| 1 | Histological Studies of Atrazine Toxicity on the Thyroid Gland in Rats显示文摘Little is known about the toxic activity of the atrazine (a herbicide, commonly used in agricultural production) on the thyroid gland. In this study the compound was administered orally in female albino rats at sublethal exposure equivalent to 0.2 LD50 doses for 6 and 12 days. At termination of dosing the anesthetized animals were killed and blood was drawn for the determination of serum triiodothyronine (T3) and thyroxin (T4). A dose-dependent decrease of serum T3 concentration was observed in all the groups (control: 0.57 nmol·L-1; 6 days: 0.35 nmol·L-1; 12 days: 0.21 nmol·L-1). The thyroid gland was examined light-microscopically. Bouin’s solution-fixed thyroids were embedded in paraffin and sections cut at 6 μm, stained separately with toluidine blue according to Slinchenko’s method. Histologically in experimental groups epithelium featured small cuboidal cells and occasional structures of the follicles confluence within epitheliomers. A dose-dependent changes of the following parameters were observed: (a) increasing of number of follicle-building thyroid cells; (b) increasing of follicular volume, (c) decreasing of nucleus volume. Investigation of the whole population of thyroid mast cells disclosed no change in degranulation intensity. By contrast, degranulation intensity was decreased in perifollicular mast cells from groups treated with atrazine in dose-dependent manner.There are no changes observed in degranulation of stromal mast cells. These results suggesting that differences in response to the atrazine might account for an aspect of the functional heterogeneity within the rat thyroid mast cell population. | I. N. KORNILOVSKAYA M. V. GORELAYA V. S. USENKO L. V. GERBILSKY AND V. A. BEREZIN(Dept. of Histology, Dniepropetrovsk Medical Institute, Dept. of Biochemistry, Dniepropetrovsk State University, Gagarin Ave. 72,Dniepropetrovsk 320625,Ukraine) | 1996 | Biomedical and Environmental Sciences1996，9，1： | 4 |
| 2 | Simultaneous analysis of select pharmaceuticals and personal care products in fish tissue using pressurized liquid extraction combined with silica gel cleanup显示文摘 | Bikram Subedi Mohammad A. Mottaleb C. Kevin Chambliss Sascha Usenko | 2011 | Journal of Chromatography A2011，，37： | 2 |
| 3 | Immunohistochemical analysis of Ki-67,PCNA and S6K1/2 expression in human breast cancer显示文摘 | LyzogubovV Khozhaenko Y Usenko V | 2005 | Exp Oncol2005，27，2： | 1 |
| 4 | Silicon-on-insulator technology for microelectromechanical applications 显示文摘 | Usenko A Y Canrr W N | 1999 | Semioanduetor Physics Quantum Electronics & Optoelectronics1999，1，1： | 1 |
| 5 | In vivo evaluation of carbon fullerene toxicity using embryonic zebrafish 显示文摘 | Usenko C Y Harper S L Tanguay R L | 2007 | Carbon2007，45，9： | 1 |
| 6 | Occurrence of pharmaceuticals and personal care products in fish: Re- suits of a national pilot study in the United States 显示文摘 | Rarnirez A J Brain R A Usenko S | 2009 | Environmental Toxicology and Chemistry2009，28，12： | 1 |
| 7 | Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish 显示文摘 | USENKO C Y HARPER S L TANGUAY R L | 2008 | Toxicology and Applied Pharmacology2008，229，1： | 1 |
| 8 | Current and historical deposition of PBDEs, pesticides, PCBs, and PAHs to Rocky Mountain national park 显示文摘 | Usenko S Landers D H Appleby P G | 2007 | Envi- ronmental Science & Technology2007，41，21： | 1 |
| 9 | In vivo evaluation of carbon futlerene toxicity using embryonic zebrafish显示文摘 | USENKO C Y HARPER S L TANGUAY R L | 2007 | Carbon2007，45，9： | 1 |
| 10 | PBDE developmental effects on embryonic zebrafish显示文摘 | USENKO C Y ROBINSON E M USENKO S | 2011 | Environ Toxicol Chem2011，30，8： | 1 |
| 11 | Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish显示文摘 | Usenko C Y Harper S L Tanguay R L | 2008 | Toxicology and Applied Pharmacology2008，229，： | 1 |
| 12 | PBDE deve- lopmental effects on embryonic zebrafish 显示文摘 | Usenko C Y Robinson E M Usenko S | 2011 | Environmental Toxicology and Chemistry2011，30，8： | 1 |
| 13 | In vivo evalua- tion of carbon fuUerene toxicity using embryonic ze- brafish 显示文摘 | Usenko C Y Harper S L Tanguay R L | 2007 | Carbon2007，45，9： | 1 |
| 14 | Cloud-Based Collaborative 3D Mapping in Real-Time With Low-CostRobots显示文摘 | Mohanarajah G Usenko V Singh M | 2015 | IEEE Transactions on Automation Science & Engineering2015，12，2： | 1 |
| 15 | Trace analysis of semivolatile organic compounds in large volume samples of snow,lake water,and groundwater显示文摘 | USENKO S HAGEMAN K J SCHMEDDING D W | 2005 | Environ Sci Technol2005，39，： | 1 |
| 16 | Surgical treatment of cardial achalasia显示文摘 | Usenko OIu Andreieshchev SA Tyvonchuk OS | | 0，，02： | 1 |
| 17 | In vivo evaluation of carbon fullerene toxicity using embryonic zebrafish 显示文摘 | Usenko C Y Harper S L Tanguay R L | 2007 | Carbon2007，45，9： | 1 |
| 18 | PBDE developmental effects on embryonic zebrafish显示文摘 | Usenko C Y Robinson E M Usenko S | 2011 | Environmental Toxicology and Chemistry2011，30，8： | 1 |
| 19 | Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish 显示文摘 | Usenko CY Harper SL Tanguay RL | 2008 | Toxicol Appl Pharmacol2008，229，1： | 1 |
| 20 | Current and historical deposition of PBDEs, pesticides, PCBs, and PAHs to rocky mountain national park显示文摘 | Usenko S Landers D H Appleby P G | 2007 | Environmental Science & Technology2007，41，21： | 1 |
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