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66篇 您的检索式:作者名="Upadya"
    题名 作者 年代 出处 被引量
1Understanding the interaction of hepatitis C virus with host DEAD-box RNA helicases显示文摘The current therapeutic regimen to combat chronic hepatitis C is not optimal due to substantial side effects and the failure of a significant proportion of patients to achieve a sustained virological response.Recently developed direct-acting antivirals targeting hepatitis C virus(HCV)enzymes reportedly increase the virologic response to therapy but may lead to a selection of drug-resistant variants.Besides directacting antivirals,another promising class of HCV drugs in development include host targeting agents that are responsible for interfering with the host factors crucia for the viral life cycle.A family of host proteins known as DEAD-box RNA helicases,characterized by nine conserved motifs,is known to play an important role in RNA metabolism.Several members of this family such as DDX3,DDX5 and DDX6 have been shown to play a role in HCV replication and this review will summarize our current knowledge on their interaction with HCV.As chronic hepatitis C is one of the leading causes of hepatocellular carcinoma,the involvement of DEADbox RNA helicases in the development of HCC will also be highlighted.Continuing research on the interaction of host DEAD-box proteins with HCV and the contribution to viral replication and pathogenesis could be the panacea for the development of novel therapeutics against HCV.Megha Haridas Upadya Jude Juventus Aweya Yee-Joo Tan 2014World Journal of Gastroenterology2014,20,11:6
2Predictors and consequences of pneumonia in critically ill patients with stroke显示文摘Anupama Upadya Natalya Thorevska Kanaga N Sena Constantine Manthous Yaw Amoateng-Adjepong 2004Journal of Critical Care2004,,1:3
3Predictors and consequ-ences of pneumonia in critically ill patients with stroke显示文摘Upadya A Thorevska N Sena KN 2004J CritCare2004,19,1:1
4Comparison of intra-peritoneal bupivacaine and intravenous paracetamol for postoperative pain relief after laparoscopic cholecystectomy显示文摘Upadya M Pushpavathi SH Seetharam KR 2015Anesth Essays Res2015,9,1:1
5Identifying patients with degenerative mitral regurgitation for mitral valve repair and replacement:a transesophageal echocardiographic study显示文摘Chaudhry FA Upadya SP Singh VP 2004J Am Soc Echocardiogr2004,17,9:1
6Fluid balance and weaning outcomes 显示文摘Upadya A Tilluckdharry L Muralidharan V 2005Intensive Care Med2005,31,12:1
7Comparison of intra- per- itoneal bupivaeaine and intravenous paraeetamol for postoperative pain relief after laparoscopic eholeeysteetomy显示文摘Upadya M Pushpavathi SH Seetharam KR 2015Anesth Essays Res2015,9,1:1
8Efflux pump inhibitor potentiates antimicrobial photodynamic inactivation of Enterococcus faecalis biofilm显示文摘Kishen A Upadya M Tegos GP 2010Photochem Photobiol2010,86,6:1
9Predictors and consequences of pneumonia in critically ill patients with stroke显示文摘UPADYA A THOREVSKA N SENA KN 2004J Crit Care2004,19,:1
10Role of efflux pump inhibitors on the antibiofilm efficacy of calcium hydroxide,chitosan nanoparticles,and light-activated disinfection显示文摘Upadya M Shrestha A Kishen A 2011J Endod2011,37,10:1
11Fluid balance and weaning outcomes 显示文摘Upadya A Tilluckdharry L Muralidharan V 2005Intensive Care Med2005,31,12:1
12Tako tsubo cardiomyopathy ( transient left ventricular apical ballooning) : case report of a myocardial perfusion echocardiogram study 显示文摘Upadya SP Hoq SM Pannala R 2005J Am Soc Echocardiogr2005,18,3:1
13Fluid balance and weaning outcomes显示文摘Upadya A Tilluckdharry L Muralidharan V 2005Intens Care Med2005,31,12:1
14Compari- son of intra - peritoneal bupivacaine and intravenous paracelamol ior postoperative pain relief after laparoscopic choiecystectomy 显示文摘UPADYA M PUSHPAVATHI S H SEETHARAM K R 2015Anesth Essays Res2015,9,1:1
15Predictors and consequences of pneumonia in critically ill patients with stroke 显示文摘Upadya A Thorevska N Sena KN 2004J CritCare2004,19,1:1
16Predictors and con-sequences of pneumonia in critically ill patients with stroke显示文摘Upadya A Thorevska N Sena KN 2004J Crit Care2004,19,9:1
17Comparison of bolus phenylephrine, ephedrine and mephentermine for maintenance of arterial pressure during spinal anesthesia in cesarean section 显示文摘BHATYARAI B BHAT S Y UPADYA M 2010JNMA Journal of the Nepal Medical Association2010,49,177:1
18Predictors and consequences of pneumonia in critically ill patients with stroke 显示文摘Upadya A Thorevska N Sena KN 2004J Crit Care2004,19,1:1
19Fluid balance and weaning outcomes显示文摘Upadya A Tilluckdharry L Muralidharan V 2005Intensive Care Med2005,31,12:1
20Predictors and consequences of pneumonia in critically ill patients with stroke 显示文摘Upadya A Thorevska N Sena KN 2004J Crit Care2004,19,1:1
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