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| 1 | Hepatic steatosis is associated with an increased risk of carotid atherosclerosis显示文摘AIM: Although an association between helatic steatosis and vascular risk factors has been described, direct relationships between fatty liver and atherosclerosis have not yet been investigated. The aim of the present study has been to investigate those relationships.METHODS: The Study of Health in Pomerania examined a random population sample aged between 20 and 79 years.A study population of 4 222 subjects without hepatitis B and C infections and without liver cirrhosis was available for the present analysis. Hepatic steatosis was defined sonographically and intima-media thickness (IMT) as well as plaque prevalence were estimated by carotid ultrasound.RESULTS: The prevalence rate of hepatic steatosis was 29.9%. Among subjects aged ≥45 years, an association between hepatic steatosis and IMT of the carotid arteries was found in bivariate analysis, but not after adjustment for atherosclerotic risk factors. Individuals with fatty liver had more often carotid plaques than persons without fatty liver (plaque prevalence rate 76.8% vs 66.6%; P<0.001).This association persisted after adjustment for confounding factors and was predominantly present in subjects with no to mild alcohol consumption.CONCLUSION: There is an independent association between hepatic steatosis and carotid atherosclerotic plaques. Metabolic changes due to nonalcoholic fatty liver disease may explain this relationship. | Henry V(o|¨)lzke Daniel M.Robinson Volker Kleine Roland Deutscher Wolfgang Hoffmann Jan Lüdemann Ulf Schminke Christof Kessler Ulrich John | 2005 | World Journal of Gastroenterology2005，11，12： | 29 |
| 2 | High-Density Lipoprotein: Vascular Protective Effects, Dysfunction, and Potential as Therapeutic Target显示文摘 | Thomas F. Lüscher Ulf Landmesser Arnold von Eckardstein Alan M. Fogelman | 2014 | Circulation Research2014，，1： | 1 |
| 3 | Synthesis and scale-up of HNIW from 2, 6, 8, 12-tetraacetyl-4, 10-dibenzyl-2, 4, 6, 8, 10, 12-hexaazaisowurtzitane显示文摘 | Nikolaj V L Ulf W Patrick G | 2000 | Org Proc Res & Development2000，4，3： | 1 |
| 4 | 难治性类风湿关节炎的临床特点:一项国际问卷调查研究显示文摘目的尽管按照目前欧洲抗风湿联盟(EULAR)的推荐对类风湿关节炎(rheumatoid arthritis,RA)患者进行治疗,难治性RA患者的临床症状却仍然没有得到完全控制,目前EULAR指南主要关注的是RA的早期治疗和药物治疗。本研究的目的在于分析难治性RA患者的临床特点,以及在患者管理中需要探索然而现有EULAR指南并未涉及的问题。方法对多个国家的风湿科医生进行问卷调查,分析难治性RA的临床特点。问卷包括多选题以及开放性问题,从开放性问题的回答中发现需要进一步阐明的问题以及现有EULAR指南需要增加的内容。结果410名受访者完成了调查问卷,关于难治性RA的特点:50%受访者认为基于28个关节评估的疾病活动评分(disease activity score assessing 28 joints,DAS28)>3.2或存在疾病活动的征象;42%受访者认为疲劳是其特点;48%认为至少两种传统合成改变病情抗风湿药(DMARDs)以及使用至少两种生物制剂或靶向合成DMARDs治疗失败;89%认为糖皮质激素不能减量到5 mg/天或泼尼松不能减量到10 mg/天或同等剂量的其他激素。另外,现有EULAR指南中应增加合并症和关节外表现的干预以及多种药物联合治疗等重要内容。结论目前风湿科医生对难治性RA的定义有很大争议。难治性RA患者的很多重要问题目前EULAR指南中均没有涉及。 | Nadia MT Roodenrijs Maria J H de Hair Marlies C van der Goes Johannes WG Jacobs Paco MJ Welsing Désirée van der Heijde Daniel Aletaha Maxime Dougados Kimme L Hyrich Iain B McInnes Ulf Mueller-Ladner Ladislav Senolt Zoltan Szekanecz Jacob Mvan Laar Nagy Gyorgy 黄艳荣(译) 张卓莉(审校) | 2019 | 英国医学杂志中文版2019，22，2： | 1 |
| 5 | Synthesis and scale-up of HNIW from 2,6,8,12-tetraacetyl-4,10-dibenzyl-2,4,6,8,10,12-hexaazaisowurtzitane显示文摘 | V L Nikolaj W Ulf G Patrick | 2000 | Org Proc Res & Develop2000，4，3： | 1 |
| 6 | Altered Activation of Endothelial Anti- and Proapoptotic Pathways by High-Density Lipoprotein from Patients with Coronary Artery Disease: Role of High-Density Lipoprotein–Proteome Remodeling显示文摘 | Meliana Riwanto Lucia Rohrer Bernd Roschitzki Christian Besler Pavani Mocharla Maja Mueller Damir Perisa Kathrin Heinrich Lukas Altwegg Arnold von Eckardstein Thomas F. Lüscher Ulf Landmesser | 2013 | Circulation2013，，8： | 1 |
| 7 | 瑞典中部法伦地区1000年铜生产对环境的影响显示文摘瑞典中部的法伦地区在铜生产过程中向大气中排放二氧化硫(SO_2)和金属的历史至少有1000年。在17世纪,排放达到高峰,当时,法伦地区铜产量占世界铜供应量的2/3。因此,该地区为研究酸沉降和金属污染的长期效应,包括随后3个世纪降低二氧化硫排放和金属沉降的恢复提供了一个难得的机会。本文对当地二氧化硫的排放进行了1000年的回顾,估算了二氧化硫的大气浓度和干沉降,及对土壤和湖泊的酸化和金属污染。尽管长期以来二氧化硫的沉降超过了临界负荷,但土壤酸化仅局限于矿区西北和东南12km污染最严重的范围内。根据湖泊沉积物中的硅藻分析,14个湖泊中仅有8个为酸化型(0.4~0.8 pH单位)。可能是由于大量的硫酸盐仍然累积在土壤中,以及土地利用方式发生了变化,这些湖泊目前仍处于酸化状态。 | Anna S.Ek Stefan Lfgren Johan Bergholm Ulf Qvarfort 晏维金 | 2001 | AMBIO-人类环境杂志2001，30，2： | 1 |
| 8 | Impaired Endothelial Repair Capacity of Early Endothelial Progenitor Cells in Prehypertension: Relation to Endothelial Dysfunction显示文摘 | Giovanna Giannotti Carola Doerries Pavani S. Mocharla Maja F. Mueller Ferdinand H. Bahlmann Tibor Horvàth Hong Jiang Sajoscha A. Sorrentino Nora Steenken Costantina Manes Mario Marzilli K. Lenhard Rudolph Thomas F. Lüscher Helmut Drexler Ulf Landmesser | 2010 | Hypertension2010，，6： | 1 |
| 9 | 1976-1983, a critical period in the history of heparin: the discoveryof the antithrombin binding site 显示文摘 | Maurice P Benito C Ulf L | 2003 | Biochimie2003，85，： | 1 |
| 10 | Synthesis and scale-up of HNIW from 2,6,8,12-tetraacetyl-4,10-dibenzyl-2,4,6,8,10,12-hexaazaisowurtzitane显示文摘 | Nikolaj V L Ulf W Patrick G | 2000 | Organic Process Research and Develepment2000，4，3： | 1 |
| 11 | Overexpression of a cytosolic hydroxymethylglutaryl-CoA reductase leads to squalene accumulation in yeast显示文摘 | Polakowski T Ulf S Christine L | | 0，，： | 1 |
| 12 | Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae显示文摘 | Markus V Ulf S Christine L | | 0，，： | 1 |
| 13 | In vitro bioaccessibility of 13-carotene from heat-processed orange-fleshed sweet potato 显示文摘 | ANTON B MARIE L A ULF S | 2009 | Journal of Agricultural and Food Chemistry2009，57，20： | 1 |
| 14 | Spontaneous correction and derotation of secondary curves after selective anterior fusion of Idiopathic scoliosis 显示文摘 | Tobias L Schulte Ulf Liljenqvist | 2006 | Spine2006，31，： | 1 |
| 15 | Chemspot:a hybrid system for chemical named entity recognition显示文摘 | TIM R MICHAEL W ULF L | 2012 | Bioinformatics2012，28，12： | 1 |
| 16 | Novel Insights Into the Critical Role of Bradykinin and the Kinin B2 Receptor for Vascular Recruitment of Circulating Endothelial Repair–Promoting Mononuclear Cell Subsets: Alterations in Patients With Coronary Disease显示文摘 | Nicolle Kr?nkel Kira Kuschnerus Maja Müller Timo Speer Pavani Mocharla Paolo Madeddu Michael Bader Thomas F. Lüscher Ulf Landmesser | 2013 | Circulation2013，，5： | 1 |
| 17 | Black holes in asymptotically Lifshitz spacetime显示文摘 | Ulf H. Danielsson Lárus Thorlacius | 2009 | Journal of High Energy Physics2009，，03： | 1 |
| 18 | Angiotensin Ⅱinduces endothelial xan- thine oxidase activation: role for endothelial dysfunction in patients with coronary disease显示文摘 | Ulf L Stephan S Christoph P | 2007 | Arterioscler Thromb Vasc Biol2007，27，4： | 1 |
| 19 | Angiotensin Ⅱ induces endotheial xanthine oxidase activation: role for endothelial dysfunction in patients with coronary disease显示文摘 | Ulf L Stephan S Christoph P | 2007 | Arterioscler Thromb Vasc Biol2007，27，4： | 1 |
| 20 | Percutaneous plating of distal tibial frac- tures Prehminary results in 21 patients显示文摘 | Tomas B Sune L Ulf L | 2004 | Injury2004，35，6： | 1 |
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