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| 1 | Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes显示文摘This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further research in this understudied malignancy. Pancreatic adenocarcinoma is a lethal condition with a rising incidence, predicted to become the second leading cause of cancer death in some regions. It often presents at an advanced stage, which contributes to poor five-year survival rates of 2%-9%, ranking firmly last amongst all cancer sites in terms of prognostic outcomes for patients. Better understanding of the risk factors and symptoms associated with this disease is essential to inform both health professionals and the general population of potential preventive and/or early detection measures. The identification of high-risk patients who could benefit from screening to detect pre-malignant conditions such as pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasms and mucinous cystic neoplasms is urgently required, however an acceptable screening test has yet to be identified. The management of pancreatic adenocarcinoma is evolving, with the introduction of new surgical techniques and medical therapies such as laparoscopic techniques and neo-adjuvant chemoradiotherapy, however this has only led to modest improvements in outcomes. The identification of novel biomarkers is desirable to move towards a precision medicine era, where pancreatic cancer therapy can be tailored to the individual patient, while unnecessary treatments that have negative consequences on quality of life could be prevented for others. Research efforts must also focus on the development of new agents and delivery systems. Overall, considerable progress is required to reduce the burden associated with pancreatic cancer. Recent, renewed efforts to fund large consortia and research into pancreatic adenocarcinoma are welcomed, but further streams will be necessary to facilitate the momentum needed to bring breakthroughs seen for other cancer sites. | Andrew McGuigan Paul Kelly Richard C Turkington Claire Jones Helen G Coleman R Stephen McCain | 2018 | World Journal of Gastroenterology2018，24，43： | 140 |
| 2 | Flowering and Fruiting Phenology of 24 Plant Species on the North Slope of Mt. Qomolangma (Mt. Everest)显示文摘Phenological background information for alpine species is limited from extremely high altitudes. Flowering and fruiting phenology was monitored for 24 plant species at 5,180 m a.s.l. near the base camp area on the north slope of Mt. Qomolangma (Mt. Everest) in Tibet, western China. The dates of first flowering, peak flowering, end of flowering, first fruiting, peak fruiting and flowering period were recorded. There was a wide variation in onset of flowering, long flowering duration, a relative synchrony between the onset of flowering and fruiting, and one species was exclusively vegetative. These results suggest that the species have evolved various phenological strategies as adaptations to the short growing season with limited resources and pollinators in this harsh alpine environment at extremely high elevations. With a background of global warming, local plant species will represent an advancing trend in onset of flowering. | ZHANG Liyun TURKINGTON Roy TANG Ya | 2010 | Journal of Mountain Science2010，7，1： | 2 |
| 3 | Aging and atten?tional guidance during visual search ? functional neuroanatomy by positron emission tomography显示文摘 | Madden DJ Turkington TG ProvenzaleJM | 2002 | Psyehol Aging2002，17，： | 1 |
| 4 | Compensatory growth of three herbaceous perennial species:the effect of clipping and nutrient a- vailability显示文摘 | Hicks S Turkington R | 2000 | Conidia Journal of Botany2000，78，6： | 1 |
| 5 | A randomized controlled trial of cognitive-behavior therapy for persistent symptoms in schizophrenia:a five-year follow-up显示文摘 | Turkington D Sensky T Scott J | | 0，，1： | 1 |
| 6 | The effect of initial seed density on the structure of a desert annual plant community 显示文摘 | Lortie C J Turkington R | 2002 | Journal of Ecology2002，90，： | 1 |
| 7 | Design Method for Bridges on Lead-rubber Bearings显示文摘 | Turkington D H Carr A J Cooke N Moss P J | 1989 | Journal of Structural Engineering1989，115，12： | 1 |
| 8 | Implemen- ting prognostic and predictive biomarkers in CRC clinical trials 显示文摘 | Van Schaeybroeck S Allen WL Turkington RC | 2011 | Nat Rev Clin Oncol2011，8，4： | 1 |
| 9 | Effect of upper airway obstruction in acutes troke on functional outcome at 6 months显示文摘 | Turkington PM Allgar V Bamford J | 2004 | Horax2004，59，5： | 1 |
| 10 | Clinical application of PET in ontology显示文摘 | Rohren EM Turkington TG Coleman RE | 2004 | Radiology2004，231，2： | 1 |
| 11 | Informed traders and their market preference:Empirical evidence from prices and volumes of options and stock显示文摘 | Turkington J Walsh D | | 0，，05： | 1 |
| 12 | Sandstone weathering:a century of research and innovation显示文摘 | TURKINGTON A V PARADISE T R | 2005 | Geomorphology2005，67，12： | 1 |
| 13 | Cognitive-behaviour therapy for schizophrenia:a review显示文摘 | Rathod Shanaya Turkington Douglas | 2005 | Current Opinion In Psychiatry2005，18，2： | 1 |
| 14 | Acceptance, effectiveness and safety of continuous positive airwaypressure in acute stroke: a pilot study显示文摘 | SCALA R TURKINGTON P M WANKLYN P | 2009 | Respir Med2009，103，1： | 1 |
| 15 | Cognitive–behaviour therapy for schizophrenia: a review显示文摘 | Shanaya Rathod Douglas Turkington | 2005 | Current Opinion in Psychiatry2005，，2： | 1 |
| 16 | Clinical applications of PET in oncology显示文摘 | Rohren EM Turkington TG Coleman RE | 2004 | Radiology2004，231，： | 1 |
| 17 | Rationate for the use of non-inva-sive ventilation in chronic ventilatory failatory failure显示文摘 | Turkington PM Elliott MW | 2000 | Thorax2000，55，5： | 1 |
| 18 | Price Discovery and Causality in the Australian Share Price Index Futures Market 显示文摘 | Turkington J Walsh D | 1999 | Australian Journal of Management1999，24，2： | 1 |
| 19 | Prevalence and Predictors of Upper Airway Obstruction in the First 24 Hours After Acute Stroke显示文摘 | P. M. Turkington J. Bamford P. Wanklyn M. W. Elliott | 2002 | Stroke: Journal of the American Heart Association2002，，8： | 1 |
| 20 | Sandstone weathering:a century of research and innovation显示文摘 | TURKINGTON A V PARADISE T R | 2005 | Geomorphology2005，，67： | 1 |
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