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| 1 | Nonalcoholic fatty liver disease-A multisystem disease?显示文摘Non-alcoholic fatty liver disease(NAFLD) is one of the most common comorbidities associated with overweight and metabolic syndrome(Met S). Importantly, NAFLD is one of its most dangerous complications because it can lead to severe liver pathologies, including fibrosis, cirrhosis and hepatic cellular carcinoma. Given the increasing worldwide prevalence of obesity, NAFLD has become the most common cause of chronic liver disease and therefore is a major global health problem. Currently, NAFLD is predominantly regarded as a hepatic manifestation of Met S. However, accumulating evidence indicates that the effects of NAFLD extend beyond the liver and are negatively associated with a range of chronic diseases, most notably cardiovascular disease(CVD), diabetes mellitus type 2(T2DM) and chronic kidney disease(CKD). It is becoming increasingly clear that these diseases are the result of the same underlying pathophysiological processes associated with Met S, such as insulin resistance, chronic systemic inflammation and dyslipidemia. As a result, they have been shown to be independent reciprocal risk factors. In addition, recent data have shown that NAFLD actively contributes to aggravation of the pathophysiology of CVD, T2 DM, and CKD, as well as several other pathologies. Thus, NAFLD is a direct cause of many chronic diseases associated with MetS, and better detection and treatment of fatty liver disease is therefore urgently needed. As non-invasive screening methods for liver disease become increasingly available, detection and treatment of NAFLD in patients with MetS should therefore be considered by both(sub-) specialists and primary care physicians. | Ivana Mikolasevic Sandra Milic Tamara Turk Wensveen Ivana Grgic Ivan Jakopcic Davor Stimac Felix Wensveen Lidija Orlic | 2016 | World Journal of Gastroenterology2016，22，43： | 32 |
| 2 | Dexmedetomidine Added to Levobupivacaine Prolongs Axillary Brachial Plexus Block显示文摘 | Aliye Esmaoglu Fusun Yegenoglu Aynur Akin Cemil Yildirim Turk | 2010 | Anesthesia & Analgesia2010，，6： | 3 |
| 3 | 第25章 水文学100年进步显示文摘本章聚焦过去100年水文学进步。这一时期出现了从实用工程水文向水文科学基础研究的显著转变,包括了对地球系统科学的贡献。本章前3节回顾理论、观测和水文预报进展。在此基础上,讨论了全球水文、陆地-大气相互作用和耦合、生态水文学和水管理等主题,同时对出现的挑战和未来方向给出建议总结。尽管评述力争全面,但对于美国气象学会(AMS)文集的读者来说,本章还是在地表水文学和水文气象阐述更全面些。 | 克里斯塔·彼得斯-利达德 FAISAL HOSSAIN L.RUBYLEUNG NATE MCDOWELL MATTHEW RODELL FRANCISCO J.TAPIADOR F.JOE TURK ANDREW WOOD 贾朋群(编译) 李婧华(编译) | 2019 | 气象科技进展2019，9，S01： | 3 |
| 4 | Evaluation by ultrasound of traumatic rib fractures missed by radiography显示文摘 | Figen Turk Ali Bekir Kurt Seher Saglam | 2010 | Emergency Radiology2010，，6： | 2 |
| 5 | CD4+ T cells and natural killer cells: Biomarkers for hepatic fibrosis in human immunodeficiency virus/hepatitis C virus-coinfected patients显示文摘AIM To characterize peripheral blood natural killer(NK) cells phenotypes by flow cytometry as potential biomarker of liver fibrosis in human immunodeficiency virus(HIV)/hepatitis C virus(HCV) coinfected patients.METHODS Peripheral mononuclear cells from 24 HIV/HCV(HBVnegative) coinfected and 5 HIV/HCV/HBV seronegative individuals were evaluated. HIV/HCV coinfected patients were divided in to groups: G1, patients with METAVIR F0-F2 and G2, patients with METAVIR F3-F4. NK surface cell staining was performed with: AntiCD3(APC/Cy7), anti-CD56(PE/Cy5), anti-CD57(APC), anti-CD25(PE), anti-CD69(FITC), anti-NKp30(PE), antiNKp46(PE/Cy7), anti-NKG2D(APC), anti-DNAM(FITC); anti-CD62L(PE/Cy7), anti-CCR7(PE), anti-TRAIL(PE), anti-Fas L(PE), anti CD94(FITC). Flow cytometry data acquisition was performed on BD FACSCanto, analyzed using Flow Jo software. Frequency of fluorescence was analyzed for all single markers. Clinical records were reviewed, and epidemiological and clinical data were obtained.RESULTS Samples from 11 patients were included in G1 and from 13 in G2. All patients were on ARV, with undetectable HIV viral load. Liver fibrosis was evaluated by transient elastography in 90% of the patients and with biopsy in 10% of the patients. Mean HCV viral load was(6.18 ± 0.7 log10). Even though, no major significant differences were observed between G1 and G2 regarding NK surface markers, it was found that patients with higher liver fibrosis presented statistically lower percentage of NK cells than individual with low to mild fibrosis and healthy controls(G2: 5.4% ± 2.3%, G1: 12.6% ± 8.2%, P = 0.002 and healthy controls 12.2% ± 2.7%, P = 0.008). It was also found that individuals with higher liver fibrosis presented lower CD4 LT count than those from G1(G2: 521 ± 312 cells/μL, G1: 770 ± 205 cells/μL; P = 0.035).CONCLUSION Higher levels of liver fibrosis were associated with lower percentage of NK cells and LTCD4+ count; and they may serve as noninvasive biomarkers of liver damage. | Natalia Laufer Diego Ojeda María Laura Polo Ana Martinez Héctor Pérez Gabriela Turk Pedro Cahn Norberto Walter Zwirner Jorge Quarleri | 2017 | World Journal of Hepatology2017，9，25： | 2 |
| 6 | The evolution of trust in information technology alliances显示文摘 | Candace E. Ybarra Thomas A. Turk | 2009 | Journal of High Technology Management Research2009，，1： | 2 |
| 7 | Re-tiling surface显示文摘 | Turk G | 1992 | Computer Graphics1992，26，2： | 2 |
| 8 | Study of the Influence of Initial Microstructure Topology on the Kinetics of Static Recrystallization Using a Cellular Automata Model 显示文摘 | Kugler G Turk R | 2006 | Computational Materials Science2006，37，3： | 1 |
| 9 | Eigenfaces for Recognition显示文摘 | Turk M Pentland A | 1991 | Journal of Cognitive Neurosicence1991，3，1： | 1 |
| 10 | Eleetrospray ionization with low-energy collisionally activated dissociation tandem mass spectrometry of glycerophospholipids: Mechanisms of fragmentation and structural characterization显示文摘 | HSU F F TURK J | 2009 | Journal of Chromatography B2009，877，26： | 1 |
| 11 | Folate receptormediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis 显示文摘 | PAULOS C M TURK M J BREUR G J | 2004 | Adv Drug Deliv Rev2004，56，8： | 1 |
| 12 | Eigenfaces for recognition 显示文摘 | Turk M Pentland A | 1991 | J of Cognitive Neuroscience1991，3，1： | 1 |
| 13 | Methionine aminopeptidase (type-2)is the common target for angiogenesis inhibitors AGM-1470 and o-valicin显示文摘 | Griffith EC Su Z Turk BE | 1997 | Chem Biol1997，4，6： | 1 |
| 14 | Eigenfaces for face recognition显示文摘 | TURK M PENTLAND A | 1991 | Journal Cognitive Neuroscience1991，3，1： | 1 |
| 15 | Prediction of subsidence due to underground mining by artificial neural networks显示文摘 | Tomaz Ambrozic Goran Turk | 2003 | Computers & Geosciences2003，29，5： | 1 |
| 16 | Rigid fluid:animation the interplay between rigid bodies and fluid显示文摘 | Carlson M Mucha P J Turk G | 2004 | ACM Transactions on Graphics2004，23，3： | 1 |
| 17 | Tregs and transplantation tolerance 显示文摘 | Walsh PT Taylor DK Turk LA | 2004 | J Clin Invest2004，114，10： | 1 |
| 18 | US multicenter experi-ence with the wingspan stent system for the treatment ofintracranial atheromatous disease:periprocedural results显示文摘 | Fiorella D Levy El Turk AS | 2007 | Stroke2007，38，3： | 1 |
| 19 | Serum CA 125 levels in patients with chronic heart failure and accompanying pleural fluid 显示文摘 | Turk HM Pekdemir H Buyukberber S | 2003 | Tumour Siol2003，24，4： | 1 |
| 20 | Eigenfaces for ecognition 显示文摘 | Turk Pentland | 1991 | Journal of Cognitive Neuroscience1991，3，1： | 1 |
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