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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | Electricity use characteristics of purpose-bulh office buildings in subtropical climates 显示文摘 | Lain C Joseph Chan YC Ricky Tsang CL | 2004 | Energy Conversion and Management2004，45，6： | 1 |
| 3 | Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway显示文摘 | Au Yeung CL Tsang TY Yau PL | 2011 | Oncogene2011，30，21： | 1 |
| 4 | HPV-16 E6 up- regulation of DNMT1 through repression of tumor sup- pressor p53显示文摘 | Yeung CL Tsang WP Tsang TY | 2010 | Oneol Rep2010，24，6： | 1 |
| 5 | Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway显示文摘 | Au Yeung CL Tsang TY Yau PL | 2011 | Oncogene2011，30，21： | 1 |
| 6 | Correlation between hepaticsteatosis,hepatic volume, and spleenvolume in live liver donors显示文摘 | ChenTY Chen CL Tsang LL | 2008 | Transplant Proc2008，40，8： | 1 |
| 7 | Electricity use characteristics of purpose-built office buildings in subtropical climates 显示文摘 | Lain JC Chan RYC Tsang CL | 2004 | Energy Conversion and Management2004，45，6： | 1 |
| 8 | HPV-16 E6 upregulation of DNMT1 through repression of tumor suppressor p53 显示文摘 | Au Yeung CL Tsang WP Tsang TY | 2010 | Oneol Rep2010，24，6： | 1 |
| 9 | Human papiUomavirus type 16 E6 induces cervical cancer cell migration through the p53/mlcroRNA-23b/urokinase-typc plasminogen activator path- way显示文摘 | Au Yeung CL Tsang TY Yau PL | 2011 | Oncogene2011，30，21： | 1 |
| 10 | Anal sphincter injuries from sta-pling instruments introducd transanally:randomized controlled study with en-doanal ultrasound and anorectal manometry显示文摘 | Ho YH Tsang C Tang CL | 2000 | Dis Colon Rec-tum2000，43，1： | 1 |
| 11 | Superparamagnectic iron oxide-enhanced magnetic resonance for tumor surveillance in cirrhotic liver before liver transplantation with explanted liver correlation显示文摘 | Tsang LL Chen CL Huang TL | | 0，，： | 1 |
| 12 | Coriolus verslcolor polysaccharide peptide slows progression of advanced non-small cell lung cancer 显示文摘 | Tsang KW Lam CL Yan C | 2003 | Respir Med2003，97，6： | 1 |
| 13 | Build- ing energy efficiency in different climates 显示文摘 | Lam Joseph C Wan Kevin KW Tsang CL | 2008 | Energy Convers Manage2008，，49： | 1 |
| 14 | Anal sphincter injuries from stapling instruments introduced transanally:randomized,controlled study with endoanal ultrasound and anorectal manometry显示文摘 | Ho YH Tsang C Tang CL | 2000 | Dis Colon Rectum2000，43，2： | 1 |
| 15 | Anal sphincter injuries from stapling instruments introducd transanally :randomized con- trolled study with endoanal ultrasound and anorectal mano- metry显示文摘 | Ho YH Tsang C Tang CL | 2010 | Diseases of the Colon & Rectum2010，34，4： | 1 |
| 16 | Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway显示文摘 | Au Yeung CL Tsang TY Yau PL | | 0，，21： | 1 |
| 17 | Anal sphincter injuries from stapling instruments introduced transanally:randomized,controlled study with endoanal ultrasound and anorectal manometry显示文摘 | Ho YH Tsang C Tang CL | 2000 | Dis Colon Rectum2000，43，2： | 1 |
| 18 | Anal sphincter injuries from stapling instruments introduced transanally: randomized controlled study with endoanal ultrasound and anorectal manometry显示文摘 | Ho YH Tsang C Tang CL | 2000 | Dis Colon Rectum2000，43，： | 1 |
| 19 | Anal sphincter injuries from stapling instruments introduced transanally:randomized,controlled study with endoanal ultrasound and anorectal manometry显示文摘 | Ho YH Tsang C Tang CL | 2000 | Dis Colon Rectum2000，43，2： | 1 |
| 20 | Anal sphincter injures from stapling instruments introduced trananally显示文摘 | Ho YH Tsang C Tsang CL | | 0，，02： | 1 |
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