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| 1 | Hepatic encephalopathy before and neurological complications after liver transplantation have no impact on the employment status 1 year after transplantation显示文摘AIM To investigate the impact of hepatic encephalopathybefore orthotopic liver transplantation(OLT) and neurological complications after OLT on employment after OLT.METHODS One hundred and fourteen patients with chronic liver disease aged 18-60 years underwent neurological examination to identify neurological complications, neuropsychological tests comprising the PSE-SyndromeTest yielding the psychometric hepatic encephalopathy score, the critical flicker frequency and the Repeatable Battery for the Assessment of Neuropsychological Status(RBANS), completed a questionnaire concerning their occupation and filled in the short form 36(SF-36) to assess health-related quality of life before OLT and 12 mo after OLT, if possible. Sixty-eight(59.6%) patients were recruited before OLT, while on the waiting list for OLT at Hannover Medical School [age: 48.7 ± 10.2 years, 45(66.2%) male], and 46(40.4%) patients were included directly after OLT. RESULTS Before OLT 43.0% of the patients were employed. The patients not employed before OLT were more often non-academics(employed: Academic/non-academic 16(34.0%)/31 vs not employed 10(17.6%)/52, P = 0.04), had more frequently a history of hepatic encephalopathy(HE)(yes/no; employed 15(30.6%)/34 vs not employed 32(49.2%)/33, P = 0.05) and achieved worse results in psychometric tests(RBANS sum score mean ± SD employed 472.1 ± 44.5 vs not employed 443.1 ± 56.7, P = 0.04) than those employed. Ten patients(18.2%), who were not employed before OLT, resumed work afterwards. The patients employed after OLT were younger [age median(range, min-max) employed 47(42, 18-60) vs not employed 50(31, 29-60), P = 0.01], achieved better results in the psychometric tests(RBANS sum score mean ± SD employed 490.7 ± 48.2 vs not employed 461.0 ± 54.5, P = 0.02) and had a higher health-related quality of life(SF 36 sum score mean ± SD employed 627.0 ± 138.1 vs not employed 433.7 ± 160.8; P < 0.001) compared to patients not employed after OLT. Employment before OLT(P < 0.001), age(P < 0.01) and SF-36 sum score 12 mo after OLT(P < 0.01) but not HE before OLT or neurological complications after OLT were independent predictors of the employment status after OLT.CONCLUSION HE before and neurological complications after OLT have no impact on the employment status 12 mo after OLT. Instead younger age and employment before OLT predict employment one year after OLT. | Henning Pflugrad Anita B Tryc Annemarie Goldbecker Christian P Strassburg Hannelore Barg-Hock Jürgen Klempnauer Karin Weissenborn | 2017 | World Journal of Hepatology2017，9，10： | 3 |
| 2 | Active at night, sleepy all day – Sleep disturbances in patients with hepatitis C virus infection显示文摘 | Meike Heeren Faina Sojref Ramona Schuppner Hans Worthmann Henning Pflugrad Anita B. Tryc Thomas Pasedag Karin Weissenborn | 2013 | Journal of Hepatology2013，，： | 2 |
| 3 | Hepatitis C virus infection and the brain显示文摘 | Karin Weissenborn Anita B. Tryc Meike Heeren Hans Worthmann Henning Pflugrad Georg Berding Martin Bokemeyer Hans L. Tillmann Annemarie Goldbecker | 2009 | Metabolic Brain Disease2009，，1： | 2 |
| 4 | Linking infection andinflammation in acute ischemic stroke显示文摘 | Worthmann H Tryc AB Deb M | 2010 | Ann N Y Acad Sci2010，1207，： | 1 |
| 5 | The temporal profile of inflammatory markers and mediators in blood after acute is- chemic stroke differs depending on stroke outcome 显示文摘 | Worthmann H Tryc A B Goldbecker A | 2010 | Cerebrovasc Dis2010，30，1： | 1 |
| 6 | Lipopolysaccharide binding protein, interleukin-10, interleukin-6 and C reactive protein blood levels in acute ischemic stroke patients with post- stroke infection显示文摘 | Worthmann H Tryc AB Dirks M | 2015 | J Neuroinflammation2015，12，1： | 1 |
| 7 | Cerebral metabolic altera- tions and cognitive dysfunction in chronic kidney disease显示文摘 | Tryc A B Alwan G Bokemeyer M | 2011 | Neph tol Dial Transplant2011，26，8： | 1 |
| 8 | The temporal profileof inflammatory markers and mediators in blood after acute ischemic stroke differs depending on stroke outcome显示文摘 | Worthmann H Tryc AB Goldbecker A | 2010 | Cerebrovasc Dis2010，30，1： | 1 |
| 9 | The temporal profileof inflammatory markers and mediators in blood after acute ische-mic stroke differs depending on stroke outcome显示文摘 | Worthmann H Tryc AB Goldbecker A | 2010 | CerebrovascDis2010，30，1： | 1 |
| 10 | Lipopolysaccharide binding protein, interleukin-10, interleukin-6 and C-reactive protein blood levels in acute ischemic stroke patients with post-stroke infection显示文摘 | Worthmann H Tryc AB Dirks M | 2015 | J Neuroinflammation2015，12，： | 1 |
| 11 | et ah linking infection and in- flammation in acute ischemie stroke显示文摘 | Worthmann H Tryc AB Deb M | 2010 | Ann N Y Acad Sei2010，1207，： | 1 |
| 12 | The temporal profile of inflammatory markers and mediators in blood after acute ischemic stroke differs depending On stroke outcome 显示文摘 | Worthmann H Tryc AB Goldbecker A | 2010 | C embrovc Dis2010，30，1： | 1 |
| 13 | The temporal profile of inflammatory markers and mediators in blood af- ter acute ischemic stroke differs depending on stroke outcome显示文摘 | WORTHMANN H TRYC A B GOLDBECKER A | 2010 | Cerebrovasc Dis2010，30，1： | 1 |
| 14 | Cirrhosis-related Parkinsonism: Prevalence, mechanisms and response to treatments显示文摘 | Tryc AB Goldbecker A Berding G | 2013 | J Hepatol2013，58，4： | 1 |
| 15 | Linking infection and inflam- mation in acute ischemic stroke 显示文摘 | Worthmann H Tryc A B Deb M | 2010 | Ann N Y Acad Sci2010，1207，10： | 1 |
| 16 | Lipopolysaccharide binding protein,interleukin- 10, interleukin- 6 and C- reactive protein blood levels in acute ischemic stroke patients with post - strokeinfection 显示文摘 | Worthmann H Tryc AB Dirks M | 2015 | Journal of Neuroinflammation2015，12，： | 1 |
| 17 | The temporal profile of inflammatory markers and mediators in blood after acute ischemic stroke differs depending on stroke outcome显示文摘 | Worthmann H Tryc AB Goldbecker A | | 0，，01： | 1 |
| 18 | The temporal profile of inflammatory markers and mediators in blood after a- cute ischemic stroke differs depending on stroke outcome 显示文摘 | Worthmann H Tryc AB Goldbecker A | 2010 | Cerebrovasc Dis2010，30，1： | 1 |
| 19 | Hepatitis C virus infection and the brain 显示文摘 | Karin Weissenborn Anita B Tryc Meike Heeren | 2009 | Metab Brain Dis2009，24，1： | 1 |
| 20 | Hepatitis C virus infection and the brain显示文摘 | Weissenborn K Tryc AB Heeren M | | 0，，： | 1 |
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