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| 1 | Development and evaluation of a safe and effective sugar-free herbal lollipop that kills cavity-causing bacteria显示文摘Dental caries (tooth decay) is caused by a specific group of cariogenic bacteria, like Streptococcus mutans, which convert dietary sugars into acids that dissolve the mineral in tooth structure. Killing cariogenic bacteria is an effective way to control or prevent tooth decay. In a previous study, we discovered a novel compound (Glycyrrhizol A), from the extraction of licorice roots, with strong antimicrobial activity against cariogenic bacteria. In the current study, we developed a method to produce these specific herbal extracts in large quantities, and then used these extracts to develop a sugar-free lollipop that effectively kills cariogenic bacteria like Streptococcus mutans. Further studies showed that these sugar-free lollipops are safe and their antimicrobial activity is stable. Two pilot human studies indicate that a brief application of these lollipops (twice a day for ten days) led to a marked reduction of cariogenic bacteria in oral cavity among most human subjects tested. This herbal lollipop could be a novel tool to promote oral health through functional foods. | Chu-hong Hu Jian He Randal Eckert Xiao-yang Wu Li-na Li Yan Tian Renate Lux Justin A. Shuffer Faina Gelman Janet Mentes Sue Spackman Janet Bauer Maxwell H. Anderson Wen-yuan Shi | 2011 | International Journal of Oral Science2011，3，1： | 3 |
| 2 | Plant-Growth-Promoting Rhizobacteria显示文摘 | Ben Lugtenberg Faina Kamilova | 2009 | Annual Review of Microbiology2009，，： | 2 |
| 3 | Active at night, sleepy all day – Sleep disturbances in patients with hepatitis C virus infection显示文摘 | Meike Heeren Faina Sojref Ramona Schuppner Hans Worthmann Henning Pflugrad Anita B. Tryc Thomas Pasedag Karin Weissenborn | 2013 | Journal of Hepatology2013，，： | 2 |
| 4 | A comparison of time to exhaustion at VO2 max in elite cyclists,kayak paddlers,swimmers and runners显示文摘 | FAINA M SARDELLA E | 1996 | Ergonomics1996，39，2： | 1 |
| 5 | A global optimization algorithm for the three-dimensional packing problem显示文摘 | Loris Faina | 2000 | European Journal or Operational Research2000，126，： | 1 |
| 6 | Frequent mutation of the PIK3CA gene in ovarian and breast cancer显示文摘 | Douglas AL Faina B Cindy JY | 2005 | Clin Cancer Res2005，11，8： | 1 |
| 7 | DNA damage induces transcriptional activation ofp73 by removing GEBPa repression on E2F1显示文摘 | Mirko M Faina V Cristina R | 2003 | Nucleic Acids Res2003，31，22： | 1 |
| 8 | Plant-Growth-Promoting Rhizobaeteria 显示文摘 | Ben Lugtenberg Faina Kamilova | 2009 | Annual Review of Microbiology2009，63，： | 1 |
| 9 | A Global Optimization Algorithm for the Three-dimens ional Packing显示文摘 | Loris Faina | 2000 | European Journal of Operational Reasearch2000，，126： | 1 |
| 10 | Energy cost of swimming of elite long-distance swimmers 显示文摘 | Amparo P Bonifazi M Faina M | 2005 | Eur J Appl Physiol2005，94，56： | 1 |
| 11 | Structural andparamagnetic properties of dilute Gai--Mn-N显示文摘 | Stefanowicz W Sztenkiel D Faina B | 2010 | Phys RevB2010，81，23： | 1 |
| 12 | A comparison of time to exhaustion at VO2 max in elite cyclists,kayak paddlers,swimmers and runners显示文摘 | Billat V Faina M Sardella F | 1996 | Ergonomics1996，39，2： | 1 |
| 13 | Application of simulated annealing to cutting stock problem显示文摘 | Faina L | 1999 | European Journal of Operational Research1999，68，： | 1 |
| 14 | An application of simulated annealing to the cutting stock problem 显示文摘 | Loris Faina | 1999 | European Journal of Operational Research1999，114，3： | 1 |
| 15 | p73 overexpression increases VEGF and reduces thrombospondin-1 production:implications for tumor angiogenesis显示文摘 | Faina Vikhanskaya Maria R Bani Patrizia Borsotti | 2001 | Oncogene2001，20，50： | 1 |
| 16 | Energy cost of swimming of elite long-distance swimmers 显示文摘 | Zamparo P Bonifazi M Faina M | 2005 | Eur J Appl Physiol2005，94，56： | 1 |
| 17 | An Application of Simulated Annealing to the Cutting Stock Problem显示文摘 | Faina L | 1999 | European Journal of Operational Research1999，114，3： | 1 |
| 18 | Decomposition of triacetone triperoxide is an entropic explosion显示文摘 | Faina Dubnikova Ronnie Kosloff Joseph Almog | 2005 | J Am Chern Soc2005，127，4： | 1 |
| 19 | Frequent mutation of the PIK3CA gene in ovarian and breast cancer显示文摘 | Douglas AL Faina B Cindy JY | 2005 | Clin Cancer Res2005，11，8： | 1 |
| 20 | Endometrial hyperplasi- a,endometrial cancer and prevention: gaps in existing re- search of modifiable risk factors 显示文摘 | Faina L Robert E Judith B | 2008 | Eur J Cancer2008，44，12： | 1 |
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