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| 1 | Budesonide induces complete remission in autoimmune hepatitis显示文摘瞄准:泼尼松和 azathioprine 为自体免疫的肝炎(AIH ) 代表标准疗法。然而,仅仅, 65% 病人进入完全的组织学的宽恕。最近, budesonide (芽) 被报导是一种有希望的选择。在这研究,我们在 AIH 估计了芽的功效和安全。方法:十八个病人(12 个女人, 6 个男人;吝啬的年龄 45.4+/-21 年) 与芽(Budenofalk ) 与 AIH 被对待在上面三次每日、跟随的 3 mg 为至少 24 wk.Seven,病人们也有主要胆汁性肝硬变(n=5 ) 或主要致硬化的胆管炎(n=2 ) 的特征。先进的肝纤维变性或肝硬化在 6 个病人是在场的。结果:十五(83%) 病人们有完全的临床、生物化学的宽恕。十个病人,与尖锐肝炎包括五,作为首要的治疗被给芽,哪个七进入宽恕。三个病人,二与肝肝硬化,没改善。有第二线的治疗的所有病人经历了长期的宽恕。组织学的宽恕也在三个病人被看见。临床上相关的导致芽的副作用与肝肝硬化(n=4 ) 仅仅在病人被记录。结论:芽在在我们有 AIH.Side 效果的病人的多数的宽恕正式就职是有效的,治疗失败主要与肝肝硬化在病人被观察。 | Antal Csepregi Christoph R(o|¨)cken Gerhard Treiber Peter Malfertheiner | 2006 | World Journal of Gastroenterology2006，12，9： | 14 |
| 2 | Breath and string test: A diagnostic package for the identification of treatment failure and antibiotic resistance of Helicobacter pylori without the necessity of upper gastrointestinal endoscopy显示文摘AIM: Helicobacter pylori ( H pylofi) resistance after failed eradication has a major impact on the outcome of a further treatment regimen. The aim of this study was to assess the validity of a non-invasive strategy using the 13C-urea breath test (UBT) and the gastric string test in identifying post-treatment resistance of Hpylori.METHODS: The UBT was routinely performed 4 to 6 wk after H pylorieradication therapy. Forty-two patients (24 females, 18 males, mean age 48 years) with a positive UBT were included in the study. A gastric string test using a capsule containing a 90 cm-long nylon fiber was performed.Before the capsule was swallowed, the free end of the string was taped to the cheek. After one hour in the stomach, the string was withdrawn. The distal 20 cm of the string was inoculated onto an agar plate and processed under microaerophilic conditions. Following the string test, upper gastrointestinal endoscopy was performed to obtain gastric biopsies for conventional culture.RESULTS: H pyloriwas successfully cultured from the gastric string in 34 patients (81%), but not in 5 patients due to contamination with oropharyngeal flora. Hpyloriwas cultured from the gastric biopsies obtained at endoscopy in 39 patients (93%).CONCLUSION: The UBT followed by the gastric string test in the case of treatment failure is a valid diagnostic strategy with the aim of determining the post-therapeutic antibiotic resistance of Hpyloriwith little inconvenience to the patient.Upper GI-endoscopy can be avoided in several cases by applying consequently this diagnostic package. | Andreas Leodolter Kathlen Wolle Ulrike von Arnim Stefan Kahl Gerhard Treiber Matthias P.Ebert Ulrich Peitz Peter Malfertheiner | 2005 | World Journal of Gastroenterology2005，11，4： | 10 |
| 3 | Acute exacerbation of autoimmune hepatitis induced by Twinrix显示文摘We report on a 26-year-old man who presented with severe jaundice and elevated serum liver enzyme activities after having received a dose of Twinrix(○R). In his past medical history, jaundice or abnormal liver function tests were never recorded. Following admission, an elevated immunoglobulin G level and antinuclear antibodies at a titer of 320 with a homogenous pattern were found. Histology of a liver biopsy showed marked bridging liver fibrosis and a chronic inflammation, compatible with autoimmune hepatitis. Treatment was started with budesonide and ursodeoxycholic acid,and led to complete normalization of the pathological liver function tests. We believe that Twinrix(○R) led to an acute exacerbation of an unrecognized autoimmune hepatitis in our patient. The pathogenesis remains to be clarified. It is tempting to speculate that inactivated hepatitis A virus and/or recombinant surface antigen of the hepatitis B virus -as seen in patients with chronic hepatitis C and unrecognized autoimmune hepatitis who were treated with interferon alpha-might have been responsible for disease exacerbation. | Antal Csepregi Gerhard Treiber Christoph R(o|¨)cken Peter Malfertheiner | 2005 | World Journal of Gastroenterology2005，11，26： | 2 |
| 4 | IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality显示文摘 | Zhang Hong Neuh?fer Patrick Song Liang Rabe Bj?rn Lesina Marina Kurkowski Magdalena U Treiber Matthias Wartmann Thomas Regnér Sara Thorlacius Henrik Saur Dieter Weirich Gregor Yoshimura Akihiko Halangk Walter Mizgerd Joseph P Schmid Roland | 2013 | Journal of Clinical Investigation2013，，3： | 2 |
| 5 | A laboratory evaluationof the wettability of fifty oil-producing reservoirs显示文摘 | TREIBER L E OWENS W W | 1972 | SPE Journal1972，12，6： | 1 |
| 6 | Structure of 2,6-dihydroxy- pyridine 3-hydroxylase from a nicotine-degrading pathway 显示文摘 | Treiber N Schulz G E | 2008 | J Mol Biol2008，379，1： | 1 |
| 7 | Serum cystatin-C as a mark- er of acute kidney injury in the newborn after perinatal hypoxia/ asphyxia显示文摘 | Treiber M Gorenjak M Balon BP | 2014 | Ther Apher Dial2014，18，1： | 1 |
| 8 | Congested traffic states in empirical observations and microscopic simulations显示文摘 | Treiber M Hemecke A Helbing D | 2000 | Physical Review E2000，62，2： | 1 |
| 9 | Relapsing polychondritis:An autoimmune disease with many faces显示文摘 | Lahmer T Treiber M von Werder A | 2010 | Autoimmun Rev2010，9，8： | 1 |
| 10 | CYP2C19 Polymorphism and Proton Pump Inhibitors显示文摘 | Klotz U Schwab M Treiber G | 2004 | Basic Clin Pharmacol Toxicol2004，95，1： | 1 |
| 11 | Imaging of prostate cancer with PET/CT and radioactively labeled choline derivates显示文摘 | Krause BJ Souvatzoglou M Treiber U | 2011 | Urol Oncol2011，7，： | 1 |
| 12 | Tip clearance-affected flow fields in a turbine blade row显示文摘 | Sell M Treiber M Casciaro C | 1999 | Proceedings of the Institution of Mechanical Engineers Part A:Journal of Power and Energy1999，213，4： | 1 |
| 13 | Mr imaging of theknee: position related changes of the menisci in asymptomaticvolunteers显示文摘 | Boxheimer L Lutz AM Treiber K | 2004 | Invest Radiol2004，39，5： | 1 |
| 14 | CYP2C19 Polymorphism and Proton Pump Inhibitors显示文摘 | Klotz U Schwab M Treiber G | 2004 | Basic Clin Pharmacol Toxicol2004，95，1： | 1 |
| 15 | Hydrolysis Reactions of Neptunium (V) 显示文摘 | LIERSE C H TREIBER W KIM J I | 1985 | Radiochim Acta1985，38，： | 1 |
| 16 | Budesonide induces complete iemission in autoimmune hepatitis 显示文摘 | Csepregi A Rocken C Treiber G | 2006 | world J Gastroenterol2006，12，： | 1 |
| 17 | Relationships among socioeconomic status,stress induced changes in cortisol,and blood pressure in African American males显示文摘 | Kapuku GL Treiber FA Davis HC | 2002 | Ann Behau Med2002，24，4： | 1 |
| 18 | The challenge to conventional blending technology显示文摘 | TREIBER S MCLEOD R S FAITAKIS Y | 1998 | Hydrocarbon Processing1998，77，6： | 1 |
| 19 | Congested traffic states in empirical observations and microscopic simulations 显示文摘 | TREIBER M HENNECKE A HELBING D | 2000 | Physical Review E2000，62，2： | 1 |
| 20 | Analytical investigation of innovation dynamics considering stochasticity in the evaluation of fitness显示文摘 | HELBING D TREIBER M SAAM J N | 2005 | Physical Review2005，71，6： | 1 |
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