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| 1 | Impact of laparoscopic surgery training laboratory on surgeon's performance显示文摘Minimally invasive surgery has been replacing the open standard technique in several procedures. Similar or even better postoperative outcomes have been described in laparoscopic or robot-assisted procedures when compared to open surgery. Moreover, minimally invasive surgery has been providing less postoperative pain, shorter hospitalization, and thus a faster return to daily activities. However, the learning curve required to obtain laparoscopic expertise has been a barrier in laparoscopic spreading. Laparoscopic surgery training laboratory has been developed to aid surgeons to overcome the challenging learning curve. It may include tutorials, inanimate model skills training(box models and virtual reality simulators), animal laboratory, and operating room observation. Several different laparoscopic courses are available with specific characteristics and goals. Herein, we aim to describe the activities performed in a dry and animal-model training laboratory and to evaluate the impact of different kinds of laparoscopic surgery training courses on surgeon's performance. Several tasks are performed in dry and animal laboratory to reproduce a real surgery. A short period of training can improve laparoscopic surgical skills, although most of times it is not enough to confer laparoscopic expertise for participants. Nevertheless, this short period of training is able to increase the laparoscopic practice of surgeons in their communities. Full laparoscopic training in medical residence or fellowship programs is the best way of stimulating laparoscopic dissemination. | Fabio C M Torricelli Joao Arthur B A Barbosa Giovanni S Marchini | 2016 | World Journal of Gastrointestinal Surgery2016，8，11： | 6 |
| 2 | Post-transplantation hepatocellular carcinoma recurrence: Patterns and relation between vascularity and differentiation degree显示文摘AIM: To evaluate the relationship between hepatocellular carcinoma(HCC) vascularity and grade; to describe patterns and vascular/histopathological variations of post-transplantation recurrence.METHODS: This retrospective study included 165 patients(143 men, 22 women; median age 56.8 years, range 28-70.4 years) transplanted for HCC who had a follow-up period longer than 2 mo. Pre-transplantation dynamic computed tomography or magnetic resonance examinations were retrospectively reviewed, classifying HCC imaging enhancement pattern into hypervascular and hypovascular based on presence of wash-in during arterial phase. All pathologic reports of the explanted livers were reviewed, collecting data about HCC differentiation degree. The association between imaging vascular pattern and pathological grade was estimated using the Fisher exact test. All follow-up clinical and imaging data were reviewed for evidence of recurrence. Recurrence rate was calculated and imaging features of recurrent tumor were collected, classifying early and late recurrences based on timing(< or ≥ 2 years after transplantation) and intrahepatic, extrahepatic and both intrahepatic and extrahepatic recurrences based onlocation. All intrahepatic recurrences were classified as hypervascular or hypovascular and the differentiation degree was collected where available. The presence of variations in imaging enhancement pattern and pathological grade between the primary tumor and the intrahepatic recurrence was evaluated and the association between imaging and histopatholgical variations was estimated by using the χ2 test. RESULTS: Of the 163 patients with imaging evidence of viable tumor, 156(95.7%) had hypervascular and 7(4.3%) hypovascular HCC. Among the 125 patients with evidence of viable tumor in the explanted liver, 19(15.2%) had grade 1, 56(44.8%) grade 2, 40(32%) grade 3 and 4(3.2%) grade 4 HCC, while the differentiation degree was not assessable for 6 patients(4.8%). A significant association was found between imaging vascularity and pathological grade(P = 0.035). Post-transplantation recurrence rate was 14.55%(24/165). All recurrences occurred in patients who had a hypervascular primary tumor. Three patients(12.5%) experienced late recurrence; the location of the first recurrence was extrahepatic in 14 patients(58.3%), intrahepatic in 7 patients(29.2%) and both intrahepatic and extrahepatic in 3 patients(12.5%). Two patients had a variation in imaging characteristics between the primary HCC(hypervascular) and the intrahepatic recurrent HCC(hypovascular), while 1 patient had a variation of histopathological characteristics(from moderate to poor differentiation), however no association was found between imaging and histopathological variations.CONCLUSION: A correlation was found between HCC grade and vascularity; some degree of variability may exist between the primary and the recurrence imaging/histopathological characteristics, apparently not correlated. | Annarita Pecchi Giulia Besutti Mario De Santis Cinzia Del Giovane Sofia Nosseir Giuseppe Tarantino Fabrizio Di Benedetto Pietro Torricelli | 2015 | World Journal of Hepatology2015，7，2： | 5 |
| 3 | The effect of zoledronate-hydroxyapatite nanocomposites on osteoclasts and osteoblast-like cells in vitro显示文摘 | Elisa Boanini Paola Torricelli Massimo Gazzano Milena Fini Adriana Bigi | 2011 | Biomaterials2011，，2： | 2 |
| 4 | Flexible Ureteroscopy With a Ureteral Access Sheath: When to Stent?显示文摘 | Fabio Cesar Miranda Torricelli Shubha De Bryan Hinck Mark Noble Manoj Monga | 2013 | Urology2013，，： | 2 |
| 5 | Laser biostimulation of cartilage: in vitro evaluation显示文摘 | Torricelli P Giavaresi G Fini M | 2001 | Biomed Pharmacother2001，55，2： | 1 |
| 6 | Optimized survival of hippocampal neurons in B27 supplemented neurobasal, a new ser- um-free medium combination 显示文摘 | Brewer G J Torricelli J R Evege E K | 1993 | N eurosci Res1993，35，5： | 1 |
| 7 | Functionalization of biomi-metic calcium phosphate bone cements with alendronate 显示文摘 | Panzavolta S Torricelli P Bracci B | 2010 | Journalof Inorganic Biochemistry2010，104，2： | 1 |
| 8 | A neural-based remote eye gaze tracker under natural head motion显示文摘 | Diego Torricelli Silvia Conforto Maurizio Schmid | 2008 | ComputerMethods and Programs in Biomedicine2008，92，1： | 1 |
| 9 | MMSE filtering of generalised signal dependent noise in spatial and shift invariant wavelet domains显示文摘 | Argenti F Torricelli G Alparone L | 2006 | Signal Processing2006，86，8： | 1 |
| 10 | Identication of hematopoietic progenitor cells in human amniotic fluid before the 12th week of gestation显示文摘 | Torricelli F Brizzi L Bernabei PA | 1993 | Ital J Anat Embryol1993，98，2： | 1 |
| 11 | A neural-based remote eye gaze tracker under natural head motion 显示文摘 | Torricelli D Conforto S Schmid M | 2008 | Computer Methods and Programs in Biomedicine2008，92，1： | 1 |
| 12 | Osteosarcoma magnetic resonance imaging of the effects of preoperative chemotherapy 显示文摘 | Spina V Torricelli P Manfrini M | 1993 | Radiol Med1993，85，6： | 1 |
| 13 | Sclerosing stromal tumors of the ovary:US,CT,and MRI findings 显示文摘 | Torricelli P Caruso Lombardi A | 2002 | Abdom Imaging2002，27，： | 1 |
| 14 | Evaluating the automated thermedx fluid management system in a ureteroscopy model 显示文摘 | De S Torricelli FC Sarkissian C | 2014 | J Endourol2014，28，5： | 1 |
| 15 | In vitro study on silk fibroin textile structure for anterior cruciate ligament regeneration 显示文摘 | Faro S Torricelli P Giavaresi G | 2013 | Mater Sci Eng C Mater Biol Appl2013，33，7： | 1 |
| 16 | Optimized survival of hippocampal neurons in B27-supplemented neuronbasal^TM , a new serum-free medium combination 显示文摘 | Brewer GJ Torricelli JR Evege EK | 1993 | J Neurosci Res1993，35，5： | 1 |
| 17 | In vitro corrosion study by EIS of an equiatomic NiTi alloy and an implant quality AISI 316 stainless steel 显示文摘 | Rondelli G Torricelli P Fini M | 2006 | J Biomed Mater Res B Appl Biomater2006，79，2： | 1 |
| 18 | The healing of confined critical size cancellous defects in the presence of silk fibroin hydrogel显示文摘 | Fini M Motta A Torricelli P | 2005 | Biomaterials2005，26，17： | 1 |
| 19 | Calcium phosphate thin films synthesized by pulsed laser deposition:Physico-chemical characterization and in vitro cell response 显示文摘 | Mihailescu I N Torricelli P Bigi A | 2005 | Applied Surface Science2005，248，34： | 1 |
| 20 | Optimized survival ofhippocampal neurons in B27-supplemented Neurobasal,a new ser-um-free medium combination显示文摘 | Brewer GJ Torricelli JR Evege EK | 1993 | J Neurosci Res1993，35，5： | 1 |
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