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| 1 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 2 | High prevalence of viable Mycobacterium avium subspecies paratuberculosis in Crohn's disease显示文摘AIM:To examine the detection rate of viable Mycobacterium avium subspecies paratuberculosis(MAP) in patients with inflammatory bowel disease [Crohn's disease(CD) and ulcerative colitis(UC)].METHODS:Thirty patients with CD(15 with at least one NOD2/CARD15 mutation),29 with UC,and 10 with no inflammatory bowel disease(IBD).were tested for MAP by polymerase chain reaction(specific IS900 fragment) and blood culture.RESULTS:MAP DNA was detected in all original blood samples and 8-wk blood cultures(CD,UC and non-IBD).Positive MAP DNA status was confirmed by dot blot assays.All 69 cultures were negative by acid-fast Ziehl-Neelsen staining.Viable MAP,in spheroplast form,was isolated from the 18-mo blood cultures of all 30 CD patients,one UC patient,and none of the non-IBD controls.No association was found between positive MAP cultures and use of immunosuppressive drugs or CDassociated single nucleotide polymorphisms.CONCLUSION:MAP is widely present in our area and MAP DNA can be recovered from the blood of CD,UC and non-IBD patients.However,MAP spheroplasts were only found in CD patients. | Juan L Mendoza Amparo San-Pedro Esther Culebras Raquel Cíes Carlos Taxonera Raquel Lana Elena Urcelay Fernando de la Torre Juan J Picazo Manuel Díaz-Rubio | 2010 | World Journal of Gastroenterology2010，16，36： | 5 |
| 3 | AD是一种神经变性还是一种血管病变?显示文摘 | Jack C de la Torre 杨敏慧 | 2004 | 中国处方药2004，3，5： | 3 |
| 4 | Lung inflammatory response in pneumonia Monaldi Arch显示文摘 | Monton C Torres A | 1998 | Chest Dis1998，53，1： | 2 |
| 5 | 14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial显示文摘 | E Robert Greenberg Garnet L Anderson Douglas R Morgan Javier Torres William D Chey Luis Eduardo Bravo Ricardo L Dominguez Catterina Ferreccio Rolando Herrero Eduardo C Lazcano-Ponce María Mercedes Meza-Montenegro Rodolfo Pe?a Edgar M Pe?a Eduardo Salazar- | 2011 | The Lancet2011，，9790： | 2 |
| 6 | 星形胶质细胞转录组分析指导的脑卒中靶标鉴定显示文摘星形胶质细胞支持正常的脑功能,但在卒中等病理条件下,星形胶质细胞反应性激活,其也可能参与神经退行性改变。反应性星形胶质细胞增生对机体有益或有害,与环境背景有关,但其分子基础仍未得到充分解释。借助RiboTag技术,我们在特异性地短暂性大脑中动脉闭塞(tMCAO)72h后的小鼠星形胶质细胞中,纯化翻译mRNA,构建卒中特异性星形胶质细胞翻译组数据库。我们发现,与对照组脑组织相比,tMCAO后的反应性星形胶质细胞显示与A2表型相关的转录物的富集,这与神经保护相关。星形胶质细胞也会上调大量潜在的神经毒性基因。我们共鉴定了1003个基因和38个转录因子的差异表达,其中Stat3,Sp1和Spi1变化最明显。为了进一步探索Stat3介导的通路对卒中发病机制的影响,我们选择星形胶质细胞特异性条件性缺失Stat3的小鼠制造tMCAO模型,发现这些小鼠的局灶性缺血卒中体积减少,且梗死72h后小鼠的运动结果改善。综上所述,本研究扩展了新兴的星形胶质细胞特异性靶向卒中治疗数据库,并肯定了星形胶质细胞是脑功能的关键保障细胞。 | Rakers C Schleif M Blank N Matu?ková H Ulas T H?ndler K Torres SV Schumacher T Tai K Schultze JL Jackson WS Petzold GC 聂昊 | 2019 | 神经损伤与功能重建2019，14，6： | 2 |
| 7 | Autosomal dominant polycystic kidney disease显示文摘 | Vicente E Torres Peter C Harris Yves Pirson | 2007 | The Lancet2007，，9569： | 2 |
| 8 | RNA virus populations as quasispecies显示文摘 | Holland J J de la Torre J C Steinhauer D A | 1992 | Curr Top Microbiol Immunol1992，176，： | 2 |
| 9 | COPD heterogeneity: gender differences in the multidimensional BODE index 显示文摘 | de Torres JP Casanova C de Gareini AM | 2007 | International Journal of Chronic Obstructive Pulmonary Disease2007，2，2： | 1 |
| 10 | Analysis of the molecular species generated by MDM2 gene amplification in liposarcomas显示文摘 | Tamborini E Della Torre G Lavarino C | 2001 | Int J Cancer2001，92，6： | 1 |
| 11 | The relationship between spe- cific tissue lesions and pain severity in persons with knee osteoarthri- tis显示文摘 | Torres L Dunlop DD Peterfy C | 2006 | Osteoarthritis Cartilage2006，14，0： | 1 |
| 12 | ADC measure-ments at low and high structure with b values:insight into normalbrain clinical DWI显示文摘 | Garcia Santos JM Ordonez C Torres del Rio S | 2008 | Magn Reson Imaging2008，26，1： | 1 |
| 13 | Kinetics of consumption of fermentation products by anode-respiring bacteria显示文摘 | Torres C I Kato Marcus A Rittmann B E | 2007 | Appl Microbiol Biotechnol2007，77，3： | 1 |
| 14 | Robust Ck/C0 generalized FEM approximations for higher-order conformity requirements:Appfication to Reddy's HSDT model for anisotropic laminated plates thoery显示文摘 | Mendonca P T R Barcellos C S Torres DAF | 2013 | Compos Struct2013，，96： | 1 |
| 15 | Conjugation of cate-chins with cysteine generates antioxidant compounds with en-hanced neuroprotective activity 显示文摘 | Torres JL Lozano C Maher P | 2005 | Phytochemistry2005，66，17： | 1 |
| 16 | Mieroalbuminuria and bypoxemia in patients with chronic obstructive pulmonary disease 显示文摘 | Casanova C de Torres JP Navarro J | 2010 | Am J Respir Crit Care Med2010，182，8： | 1 |
| 17 | Nitrosopumilus maritimus genome reveals unique mechanisms for nitrification and autotrophy in globally distributed marine crenarchaea 显示文摘 | WALKER C B DE LA TORRE J R KLOTZ M G | 2010 | Proceedings of the National Academy of Sciences of USA2010，107，： | 1 |
| 18 | Effect of dental surface treatment with Nd:YAG and Er:YAG lasers on bond strength of resin composite to recently bleached enamel显示文摘 | Rocha Gomes Torres C Caneppele TM Del Moral de Lazari R | 2012 | Laser Med Sci2012，27，4： | 1 |
| 19 | Genetic relations- hips among Orobanche pecies as revealed by PAPD analysis显示文摘 | Roman B Alfaro C Torres AM | 2003 | Ann Bot(Lond)2003，91，6： | 1 |
| 20 | Major Variations in Anatomical Origin of the Coronary Arteries:Angiographic Observations in 4250 Patients without Associated Congenital Heart Disease显示文摘 | Engel HJ Torres C Page HL | 1975 | Cathet Cardiovasc Diagn1975，1，2： | 1 |
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