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| 1 | 氯吡格雷联合阿司匹林与单用阿司匹林预防动脉粥样硬化血栓性事件的比较 | Bhatt D.L. Fox K.A.A. Hacke W. E.J. Topol 罗亮 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，0，7： | 9 |
| 2 | 欢迎人工智能临床研究的新指南显示文摘目前,人工智能在医学领域的临床试验数量十分有限,因此相关研究方案和报告的首份指南的出现恰逢其时。更好的研究方案设计,以及一致、完整的数据展示将极大地促进对这些试验的理解和验证,并促进该领域向前发展。 | 熊云云(译) 李子孝(译) 丁玲玲(译) 谷鸿秋(译) 王春娟(译) 王春雪(译) 王拥军(译) TOPOL E J | 2020 | 中国卒中杂志2020，15，11： | 7 |
| 3 | An ensemble method for gene discovery based on DNA microarray data显示文摘The advent of DNA microarray technology has offered the promise of casting new insights onto deciphering secrets of life by monitoring activities of thousands of genes simulta-neously. Current analyses of microarray data focus on precise classification of biological types, for example, tumor versus normal tissues. A further scientific challenging task is to extract dis-ease-relevant genes from the bewildering amounts of raw data, which is one of the most critical themes in the post-genomic era, but it is generally ignored due to lack of an efficient approach. In this paper, we present a novel ensemble method for gene extraction that can be tailored to fulfill multiple biological tasks including (i) precise classification of biological types; (ii) disease gene mining; and (iii) target-driven gene networking. We also give a numerical application for (i) and (ii) using a public microarrary data set and set aside a separate paper to address (iii). | Kathy L. MOSER Eric J. TOPOL | 2004 | Science China(Life Sciences)2004，47，5： | 5 |
| 4 | Tissue factor,the emerging link between inflammation,thrombosis,and remodeling 显示文摘 | PENN M S TOPOL E J | 2001 | Cir Res2001，89，1： | 2 |
| 5 | The pathogenesis and spectrum of acute coronary syndromes: from plauque formation to thrombosis 显示文摘 | Patel VB Topol EJ | 1999 | Cleve Clin J Med1999，66，9： | 2 |
| 6 | 浅析医疗大数据伦理显示文摘随着医药产业信息化及数字化水平的提高,大数据也已融入日常的诊疗过程。在医疗卫生领域,各种信息系统在医疗机构的广泛应用,以及医疗设备和仪器的数字化,使医院数据库的信息容量不断膨胀。^([1])医疗大数据是指利用常规软件工具捕获、管理和处理数据所耗时间超过可容忍时间的医疗领域的数据集。 | Eric Topol M.D 王灵芝 郝明 | 2018 | 中国医学伦理学2018，31，4： | 2 |
| 7 | Platelet glycoprotein Ⅱ b/Ⅲ a receptor in cardiovascular medicine显示文摘 | Letkovitz J Plow EF Topol EJ | 1995 | N Engl J Med1995，332，23： | 1 |
| 8 | The future of antiplatelet therapy: optimizingmanage- mentin patientswith acute coronary syndrome 显示文摘 | Topol | 2000 | Clin Cordial2000，23，16： | 1 |
| 9 | Non-destructive damage evaluation of a structure from limited modal parameters显示文摘 | Topole K G Stubbs N | 1995 | Earthquake Engineering and Structural Dynamics1995，24，： | 1 |
| 10 | Intensive statin therapy--a sea change in cardiovascular prevention显示文摘 | Topol El | 2004 | N Engl J Med2004，350，15： | 1 |
| 11 | Relationship of paraoxonase-1(PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk显示文摘 | Bhattacharyya T Nicholls SJ Topol EJ | 2008 | JAMA2008，299，11： | 1 |
| 12 | A randomized trial of late reperfusion therapy for acute myocardial infarction显示文摘 | Eric J Topol MD Robert M | 1992 | Circulation1992，85，6： | 1 |
| 13 | C-reactive protein:a golden markerOfor inflammation and coronary artery disease显示文摘 | Patel VB Robbins MA Topol EJ | 2001 | Cleve Clin Meal2001，68，6： | 1 |
| 14 | Platelet glycoprotein Ⅱb/Ⅲa receptors in cardiovascular medicine显示文摘 | Lefkovits J Plow EF Topol EJ | 1995 | N Engl J Med1995，332，23： | 1 |
| 15 | Platelet glycoprotein Ⅱb/Ⅲa receptor in cardiovascular medicine显示文摘 | Lefkovits J Plow EF Topol EJ | | 0，，23： | 1 |
| 16 | Coronary Heart Disease/Thrombosis/Myocardial-Infarction: Marked Inflammatory Sequelae to Implantation of Biodegradable and Nonbiodegradable Polymers in Porcine Coronary Arteries显示文摘 | Willem J. van der Giessen A. Michael Lincoff Robert S. Schwartz Heleen M.M. van Beusekom Patrick W. Serruys David R. Jr Holmes Stephen G. Ellis Eric J. Topol | 1996 | Circulation1996，，7： | 1 |
| 17 | Recognition of the importance of embolization in atherosclerotic vascular disease显示文摘 | Yadav JS | 2000 | Circulation2000，101，： | 1 |
| 18 | Platelet glycoprotein Ⅱb/ⅡIa receptors in cardiovascular medicine显示文摘 | PLOW EF TOPOL EJ | 1995 | N Engl J Med1995，332，23： | 1 |
| 19 | APTTs after thrombolysis and standard intravenous heparin are often low and correlate with body weight , age and sex: experience from the GUSTO Trial显示文摘 | Granger CB Califf RM Hirsh J Woodlief LH Topol EJ | 1992 | Circulation1992，86，： | 1 |
| 20 | Mammalian Mstl and Mst2 kinases play essential roles in organ size control and tumor suppression显示文摘 | Song H Mak KK Topol L Yun K Hu J Garrett L Chen Y Park O Chang J Simpson RM Wang CY Gao B Jiang J Yang Y | 2010 | Proc Natl Acad Sci U S A2010，107，4： | 1 |
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