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| 1 | Identification of CD13,CD107a,and CD164 as novel basophil-activation markers and dissection of two response patterns in time kinetics of IgE-de-pendent upregulation显示文摘Using two-colour flow cytometry >200 antibodies submitted to the 8th International Workshop of Human Leukocyte Differentiation Antigens (HLDA8) have been analyzed for their reactivity with resting and activated CD203c+ basophils. Four antibodies either non-reactive or weakly reactive with resting basophils exhibited an increased reactivity with basophils activated by anti-IgE-mediated cross-linking of the high affinity IgE receptor (FcεRI). These include antibod- ies against CD164 (WS-80160, clone N6B6 and WS-80162, clone 67D2), as well as two reagents with previously unknown specificities that were identified as CD13 (WS-80274, clone A8) and CD107a (WS-80280, clone E63-880). The activation patterns followed either the “CD203c-like” or “CD63-like” activation profile. The CD203c profile is characterized by a rapid and significant upregulation (of CD13, CD164, and CD203c), reaching maximum levels after 5- 15 min of stimulation. The phosphoinositide-3-kinase (PI3K)-specific inhibitor wortmannin inhibited the upregulation of these markers whereas 12-O-tetradecanoyl-phorbol-13-acetate (TPA) induced a rapid and FcεRI-independent upregulation within 1-2 min. In the CD63 profile, maximum upregulation (of CD63 and CD107a) was detected only after 20-40 min, and upregulation by TPA reached maximum levels after 60 min. In summary, our data identify CD13, CD107a, and CD164 as novel basophil-activation antigens. Based on time kinetics of upregulation, we hypothesize that molecules of the “CD203c group” and the “CD63 group” are linked to two different mechanisms of basophil activation. | Florian HENNERSDORF Stefan FLORIAN Andreas JAKOB Katharina BAUMGRTNER Karoline SONNECK Alfred NORDHEIM Tilo BIEDERMANN Peter VALENT Hans-Jrg BüHRING | 2005 | Cell Research2005，15，5： | 9 |
| 2 | Understanding the effects of radiative preheat and self-emission from shock heating on equation of state measurement at 100s of Mbar using spherically converging shock waves in a NIF hohlraum显示文摘Over the last six years many experiments have been done at the National Ignition Facility to measure the Hugoniot of materials,such asCHplastic at extreme pressures,up to 800 Mbar.The“Gbar”design employs a strong spherically converging shock launched through a solid ball of material using a hohlraum radiation drive.The shock front conditions are characterized using x-ray radiography.In this paper we examine the role of radiation in heating the unshocked material in front of the shock to understand the impact it has on equation of state measurements and how it drives the measured data off the theoretical Hugoniot curve.In particular,the two main sources of radiation heating are the preheating of the unshocked material by the high-energy kilo-electron-volt x-rays in the hohlraum and the heating of the material in front of the shock,as the shocked material becomes hot enough to radiate significantly.Using our model,we estimate that preheating can reach 4 eV in unshocked material,and that radiation heating can begin to drive data off the Hugoniot significantly,as pressures reach above 400 Mb. | Joseph Nilsen Andrea L.Kritcher Madison EMartin Robert E.Tipton Heather D.Whitley Damian C.Swift Tilo Doppner Benjamin L.Bachmann Amy E.Lazicki Natalie B.Kostinski Brian R.Maddox Gilbert W.Collins Siegfried H.Glenzer Roger W.Falcone | 2020 | Matter and Radiation at Extremes2020，5，1： | 5 |
| 3 | Mitogenomic phylogeny of the Asian colobine genus Trachypithecus with special focus on Trachypithecus phayrei(Blyth, 1847) and description of a new species显示文摘Trachypithecus,which currently contains 20 species divided into four groups,is the most speciose and geographically dispersed genus among Asian colobines.Despite several morphological and molecular studies,however,its evolutionary history and phylogeography remain poorly understood.Phayre’s langur(Trachypithecus phayrei) is one of the most widespread members of the genus,but details on its actual distribution and intraspecific taxonomy are limited and controversial.Thus,to elucidate the evolutionary history of Trachypithecus and to clarify the intraspecific taxonomy and distribution of T.phayrei,we sequenced 41 mitochondrial genomes from georeferenced fecal samples and museum specimens,including two holotypes.Phylogenetic analyses revealed a robustly supported phylogeny of Trachypithecus,suggesting that the T.pileatus group branched first,followed by the T.francoisi group,and the T.cristatus and T.obscurus groups most recently.The four species groups diverged from each other 4.5-3.1 million years ago(Ma),while speciation events within these groups occurred much more recently(1.6-0.3 Ma).Within T.phayrei,we found three clades that diverged 1.0-0.9 Ma,indicating the existence of three rather than two taxa.Following the phylogenetic species concept and based on genetic,morphological,and ecological differences,we elevate the T.phayrei subspecies to species level,describe a new species from central Myanmar,and refine the distribution of the three taxa.Overall,our study highlights the importance of museum specimens and provides new insights not only into the evolutionary history of T.phayrei but the entire Trachypithecus genus as well. | Christian Roos Kristofer MHelgen Roberto Portela Miguez Naw May Lay Thant Ngwe Lwin Aung Ko Lin Aung Lin Khin Mar Yi Paing Soe Zin Mar Hein Margaret Nyein Nyein Myint Tanvir Ahmed Dilip Chetry Melina Urh EGrace Veatch Neil Duncan Pepijn Kamminga Marcus AHChua Lu Yao Christian Matauschek Dirk Meyer Zhi-Jin Liu Ming Li Tilo Nadler Peng-Fei Fan Le Khac Quyet Michael Hofreiter Dietmar Zinner Frank Momberg | 2020 | Zoological Research2020，41，6： | 5 |
| 4 | A GOCE only gravity model GOSG01S and the validation of GOCE related satellite gravity models显示文摘We compile the GOCE-only satellite model GOSG01 S complete to spherical harmonic degree of 220 using Satellite Gravity Gradiometry(SGG) data and the Satellite-to-Satellite Tracking(SST) observations along the GOCE orbit based on applying a least-squares analysis.The diagonal components(V_(xx),V_(yy),V_(zz)) of the gravitational gradient tensor are used to form the system of observation equations with the band-pass ARMA filter.The point-wise acceleration observations(a_x,a_y,a_z) along the orbit are used to form the system of observation equations up to the maximum spherical harmonic degree/order 130.The analysis of spectral accuracy characteristics of the newly derived gravitational model GOSG01 S and the existing models GOTIM04 S,GODIR04S,GOSPW04 S and JYY_GOCE02S based on their comparison with the ultrahigh degree model EIGEN-6C2 reveals a significant consistency at the spectral window approximately between 80 and 190 due to the same period SGG data used to compile these models.The GOCE related satellite gravity models GOSG01 S,GOTIM05S,GODIR05 S,GOTIM04S,GODIR04 S,GOSPW04S,JYY_-GOCE02 S,EIGEN-6C2 and EGM2008 are also validated by using GPS-leveling data in China and USA.According to the truncation at degree 200,the statistic results show that all GGMs have very similar differences at GPS-leveling points in USA,and all GOCE related gravity models have better performance than EGM2008 in China.This suggests that all these models provide much more information on the gravity field than EGM2008 in areas with low terrestrial gravity coverage.And STDs of height anomaly differences in China for the selected truncation degrees show that GOCE has improved the accuracy of the global models beyond degree 90 and the accuracies of the models improve from 24 cm to 16 cm.STDs of geoid height differences in USA show that GOSGOIS model has best consistency comparing with GPSleveling data for the frequency band of the degree between 20 and 160. | Xinyu Xu Yongqi Zhao Tilo Reubelt Robert Tenzer | 2017 | Geodesy and Geodynamics2017，8，4： | 5 |
| 5 | Novel fiber-optical interferometer with miniaturized probe for in-hole measurements显示文摘Today, micro-system technology and the development of new MEMS (Micro-Electro-Mechanical Systems) are emerging rapidly. In order for this development to become a success in the long run, measurement systems have to ensure product quality. Most often, MEMS have to be tested by means of functionality or destructive tests. One reason for this is that there are no suitable systems or sensing probes available which can be used for the measurement of quasi inaccessible features like small holes or cavities. We present a measurement system that could be used for these kinds of measurements. The system combines a fiber optical, miniaturized sensing probe with low-coherence interferometry, so that absolute distance measurements with nanometer accuracy are possible. | Robert Schmitt Tilo Pfeifer Frank Depiereux Niels Knig | 2008 | Optoelectronics Letters2008，4，2： | 3 |
| 6 | Randomized Comparison of Strategies for Type B Aortic Dissection: The INvestigation of STEnt Grafts in Aortic Dissection (INSTEAD) Trial显示文摘 | Christoph A. Nienaber Hervé Rousseau Holger Eggebrecht Stephan Kische Rossella Fattori Tim C. Rehders Günther Kundt Dierk Scheinert Martin Czerny Tilo Kleinfeldt Burkhart Zipfel Louis Labrousse Hüseyin Ince | 2009 | Circulation2009，，25： | 2 |
| 7 | Image quality in conven- tional lumbar spine radiography evaluation using the post-process- ing tool diamond view显示文摘 | Tilo N Clemens R Laura RL | 2009 | Euro J Radiol2009，，70： | 1 |
| 8 | Comparative analysis of DNA extraction protocols for ancient soft tissue museum samples显示文摘DNA studies of endangered or extinct species often rely on ancient or degraded remains.The majority of ancient DNA(aDNA)extraction protocols focus on skeletal elements,with skin and hair samples rarely explored.Similar to that found in bones and teeth,DNA extracted from historical or ancient skin and fur samples is also extremely fragmented with low endogenous content due to natural degradation processes.Thus,the development of effective DNA extraction methods is required for these materials.Here,we compared the performance of two DNA extraction protocols(commercial and custom laboratory aDNA methods)on hair and skin samples from decades-old museum specimens to Iron Age archaeological material.We found that apart from the impact sample-specific taphonomic and handling history has on the quantity and quality of DNA preservation,skin yielded more endogenous DNA than hair of the samples and protocols tested.While both methods recovered DNA from ancient soft tissue,the laboratory method performed better overall in terms of DNA yield and quality,which was primarily due to the poorer performance of the commercial binding buffer in recovering aDNA. | Ming Zhang Peng Cao Qing-Yan Dai Yong-Qiang Wang Xiao-Tian Feng Hong-Ru Wang Hong Wu Albert Min-Shan Ko Xiao-Wei Mao Yi-Chen Liu Li Yu Christian Roos Tilo Nadler Wen Xiao E.Andrew Bennett Qiao-Mei Fu | 2021 | Zoological Research2021，42，3： | 1 |
| 9 | Diagnostic performance of low- dose CT for the detection of urolithiasis : a Meta- analysis 显示文摘 | TILO N THILO K GEORG B | 2008 | Am J Roentgenol2008，191，8： | 1 |
| 10 | Prior bowel resections, perianal disease, and a high initial Crohn’s disease activity index are associated with corticosteroid resistance in active Crohn’s disease显示文摘 | Cornelia M Gelbmann Gerhard Rogler Volker Gross Michael Gierend Nicole Bregenzer Tilo Andus Jürgen Sch?lmerich | 2002 | The American Journal of Gastroenterology2002，，6： | 1 |
| 11 | Randomized Comparison of Strategies for Type B Aortic Dissection: The INvestigation of STEnt Grafts in Aortic Dissection (INSTEAD) Trial显示文摘 | Christoph A. Nienaber Hervé Rousseau Holger Eggebrecht Stephan Kische Rossella Fattori Tim C. Rehders Günther Kundt Dierk Scheinert Martin Czerny Tilo Kleinfeldt Burkhart Zipfel Louis Labrousse Hüseyin Ince | 2009 | Circulation2009，，25： | 1 |
| 12 | Thrombus emboli- zation into IVC filters during catheter-directed thrombolysis for proximal deep venous thrombosis 显示文摘 | Tilo Kolbel Alaa Alhadad Stefan Acosta | 2008 | J Endovasc Ther2008，15，5： | 1 |
| 13 | Endovascular Repair of Type B Aortic Dissection: Long-term Results of the Randomized Investigation of Stent Grafts in Aortic Dissection Trial显示文摘 | Christoph A. Nienaber Stephan Kische Hervé Rousseau Holger Eggebrecht Tim C. Rehders Guenther Kundt Aenne Glass Dierk Scheinert Martin Czerny Tilo Kleinfeldt Burkhart Zipfel Louis Labrousse Rossella Fattori Hüseyin Ince | 2013 | Circulation: Cardiovascular Interventions2013，，4： | 1 |
| 14 | Spline-based Feature Curves from Point-Sampled Geometry显示文摘 | Joel D II Tilo Ochotta | 2008 | The Visual Computer2008，24，6： | 1 |
| 15 | Interferometric measurement of injection nozzles using ultra-small fiber-optical probes显示文摘The measurement of boreholes with diameters smaller than 500 μm is a demanding task that cannot be performed using state-of-the-art production metrology. In this letter, a miniaturized fiber probe with a diameter of 80 μm is presented. A probe is used for low-coherence interferometry to conduct highly precise measurements of form deviations of small boreholes. Measurements conducted in nozzles are also presented. The results prove the potential of the fiber-optical sensor for quality inspection of high-precision parts, such as injection nozzles, for common-rail diesel engines. | Tilo Pfeifer Robert Schmitt Niels Knig Guilherme Francisco Mallmann | 2011 | Chinese Optics Letters2011，9，7： | 1 |
| 16 | Hypereosinophilic Syndrome: A rare case of Loeffler' s endocarditis documented in cantiac MRI 显示文摘 | Tilo Hueseyin I Christoph A | 2011 | Inter Cardiol2011，149，1： | 1 |
| 17 | Maleic Anhydride CopolymersA Versatile Platform for Molecular Biosurface Engineering 显示文摘 | Tilo P Stefan Z Nicole H | 2003 | Biomacromolecules2003，4，： | 1 |
| 18 | Do ESD fails in systems correlate with IC ESD robustness?显示文摘 | Wolfgang Stadler Tilo Brodbeck Reinhold G(a)rtner | 2009 | Microelectronics Reliability2009，49，91011： | 1 |
| 19 | Construction of Semi-recursive PR-filter Banks via Generalised Lifting显示文摘 | Tilo Strutz Erika Muller | 2004 | Signal Processing2004，84，1： | 1 |
| 20 | 显示文摘 | MarcellP Tilo V Martin B | 1995 | Adv Mater1995，2，9： | 1 |
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