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| 1 | Basic fibroblast growth factor protects against influenza A virus-induced acute lung injury by recruiting neutrophils显示文摘Influenza virus (IAV)infection is a major cause of severe respiratory illness that affects almost every country in the world.IAV infections result in respiratory illness and even acute lung injury and death,but the underlying mechanisms responsible for IAV pathogenesis have not yet been fully elucidated.In this study,the basic fibroblast growth factor 2 (FGF2)level was markedly increased in H1N1 virus-infected humans and mice.FGF2,which is predominately derived from epithelial cells,recruits and activates neutrophils via the FGFR2-PI3K-AKT-NFKB signaling pathway.FGF2 depletion or knockout exacerbated influenzaassociated disease by impairing neutrophil recruitment and activation.More importantly,administration of the recombinant FGF2 protein significantly aUeviated the severity of IAV-induced lung injury and promoted the survival of IAV-infected mice.Based on the results from experiments in which neutrophils were depleted and adoptively transferred,FGF2 protected mice against IAV , infection by recruiting neutrophils.Thus,FGF2 plays a critical role in preventing IAV-induced lung injury,and FGF2 is a promising potential therapeutic target during IAV infection. | Keyu Wang Chengcai Lai Tieling Li Cheng Wang Wei Wang Bing Ni Changqing Bai Shaogeng Zhang Lina Han Hongjing Gu Zhongpeng Zhao Yueqiang Duan Xiaolan Yang Li Xing Lingna Zhao Shanshan Zhou Min Xia Chengyu Jiang Xiliang Wang Penghui Yang | 2018 | Journal of Molecular Cell Biology2018，10，6： | 3 |
| 2 | Polypores on Spruce in Northeast China显示文摘Poroid species of wood-inhabiting fungi growing on spruce (Picea koraiensis Nakai or Picea yezoensis (Sieb. & Zucc.) Carriere) in Northeast China were investigated during 1993-2002, and 71 species were recorded from these trees or their wood. Skeletocutis lilacina A. David & Jean Keller and Skeletocutis papyracea A. David are new to China. Fomitopsis pinicola (Sw.:Fr.) P. Karst., Onnia leporina (Fr.) H. Jahn, Perenniporia subacida (Peck) Donk, Phaeolus sckweinitzii (Fr.:Fr.) Pat., Phellinidium sulphuras... | DAI Yucheng LIU Chunjing XU Cunbao Institute of Applied Ecology. Chinese Academy of Science. Shenyang 110016. China Forestry Institute of Tiding. Liaoning Province, Tieling 112000 Fenline Nature Reserve. Heiloneiiang Academy of Forestry. Yichun 153033 | 2003 | Chinese Forestry Science and Technology2003，2，2： | 2 |
| 3 | Feasibility and effects of the semirecumbent posi- tion to prevent ventilator-associated pneumonia: A randomizedstudy显示文摘 | Van Nieuwenhoven CA Vandenbroucke-Grauls C Van Tiel FA | 2006 | Crit Care Med2006，34，2： | 1 |
| 4 | Quantitative MRI techniques of cartilage composition 显示文摘 | Matzat S J van Tiel J Gold GE | 2013 | Quant Imaging Med Surg2013，3，3： | 1 |
| 5 | p27kip1-838C》A single nucleotide polymorphism is associated with restenosis risk after coronary stenting and modulates p27kip1 promoter activity显示文摘 | van Tiel CM Bonta Pl Rittersma SZ | 2009 | Circulation2009，120，8： | 1 |
| 6 | p27kip1–838C>A Single Nucleotide Polymorphism Is Associated With Restenosis Risk After Coronary Stenting and Modulates p27kip1 Promoter Activity显示文摘 | Claudia M. van Tiel Peter I. Bonta Saskia Z.H. Rittersma Marcel A.M. Beijk Edward J. Bradley Anita M. Klous Karel T. Koch Frank Baas J Wouter Jukema Douwe Pons M Lourdes Sampietro Hans Pannekoek Robbert J. de Winter Carlie J.M. de Vries | 2009 | Circulation2009，，： | 1 |
| 7 | Nuclear receptors Nur77, Nurrl, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses 显示文摘 | Bonta PI van Tiel CM Vos M | 2006 | Arterioscler Thromb Vasc Biol2006，26，10： | 1 |
| 8 | Nuclear receptor Nurrl is expressed in and is associated with human restenosis and inhibits vascular lesion formation in mice involving inhibition of smooth muscle cell proliferation and inflammation显示文摘 | BONTA P I POLS T W VAN TIEL C M | 2010 | Circulation2010，121，18： | 1 |
| 9 | Cross-colonisation with Pseudomonas Aeruginosa of Patients in an Intensive Care Unit显示文摘 | Bergmans D C Bonten M J Tiel F H | 1998 | Thorax1998，53，12： | 1 |
| 10 | Redominant infraspinatus muscle weakness in suprascapular nerve compression显示文摘 | Tiel RL Kline DG | 2000 | J Neurosurg2000，93，3： | 1 |
| 11 | Croose colonisation with pseudomonas neruginesa of patient in an intensive care unit 显示文摘 | Bermans DCJJ Bonetn MJM Tiel FHV | 1998 | Thorex1998，53，： | 1 |
| 12 | Failure data analysis with extended Weibull distribution显示文摘 | Zhang Tieling Xie Min | | 0，，： | 1 |
| 13 | Nuclear receptor Nurrl ia ex-pressed in and is associated with human restenosis and inhibits vascularlesion formation in mice involving inhibition of smooth muscle cell prolif-eration and inflammation 显示文摘 | Bonta PI Pols TW van Tiel CM | 2010 | Circulation2010，121，18： | 1 |
| 14 | Microsurgical treatment of symptomatic sacral perineurial cysts 显示文摘 | Tiel R Harkey H | 2008 | Neurosurgery2008，63，2： | 1 |
| 15 | A series of 397 peripheral neural sheath tumors: 30 -year experience at Louisiana State University Health Sciences Center显示文摘 | Kim DH Murovic JA Tiel RL | 2005 | J Neurosurg2005，102，2： | 1 |
| 16 | Pseu- domonas aerugi-nosa of patients in all intensive care unit显示文摘 | Bergmans DC Benten MJ van Tiel FH | 2009 | Thor Rx2009，53，12： | 1 |
| 17 | Nuclear receptors Nur77,Nurr1,and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses显示文摘 | BONTA P I VAN TIEL C M VOS M | 2006 | Arterioscler Thromb Vasc Biol2006，26，： | 1 |
| 18 | Feasibility and effects of the semirecumbent position to prevent ventilator-as- sociated pneumonia:a randomized study显示文摘 | Nieuwenhoven CA Vandenbroucke-Grauls C van Tiel FH | 2006 | Critical Care Medicine2006，34，2： | 1 |
| 19 | Surgical management of 10 genitofemoral neuralgias at the Louisiana State University Health Sciences Center 显示文摘 | Murovic JA Kim DH Tiel RL | 2005 | Neurosurgery2005，56，2： | 1 |
| 20 | Crooss-colonisation with pseudomonas aeruginesa of patient in an intensive care unit显示文摘 | Bonten MJM Tiel FHV | 1998 | Thorax1998，53，9： | 1 |
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