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| 1 | 武汉地区不同人群血清HCV感染状况研究显示文摘采用Ortho抗HCV ELISA C100-3试剂对武汉地区不同人群进行了抗HCV筛选。部分阳性标本作了RIBA证实实验及HCV RNA分析。并分析了5例HCV或HBV/HCV感染者的HCV基因型。结果表明:①在献血人群中,经RIBA证实抗HCV检出率为1.20%,HCV病毒血症者为0.80%;②多次受血治疗组抗HCV检出率为13.64%;③肝病组,重症肝炎为32.00%,HCC为22.86%,CPH和轻型CAH为4.05%,婴儿肝炎综合征中为5.00%;④亚基因探针杂交结果显示:武汉地区肝病患者感染的HCV主要为HCV-K2型(60.00%)。表明:经HBsAg和ALT筛选的合格献血员血清中HCV感染率仍较高,除接受血治疗外,重症肝炎和HCC患者对HCV易感性也较高,在婴儿肝炎综合征中约5%为HCV感染引起;初步结果提示武汉地区HCV的基因型主要为HCV-K2型。 | 郝连杰 郭林生 张永东 Theilmann L 杨泽川 Takada A | 1992 | 同济医科大学学报1992，21，3： | 6 |
| 2 | 重症肝炎患者HBV与HCV双重感染的血请学调查及其意义探讨显示文摘采用Ortho抗-HCV C100-3试剂检测了61例重症乙型肝炎,66例轻型慢性乙肝和22例多次受血治疗的非肝脏疾病患者血清中抗HCV C100-3抗体。重症肝炎中,抗-HCV检出率(36.07%)不仅明显高于轻型慢性乙肝组(4.55%),也高于受血治疗组(13.64%);对比分析重症肝炎HBV/HCV双重感染组与单纯HBV感染组的总胆红素、AST/ALT比值及病死率的结果,两组有显著性差异(P<0.05),提示重症肝炎患者由于多次受血治疗及肝脏本身的严重病变,因而对HCV的易感性较高;HBV/HCV双重感染可能加剧了肝脏的损害,加速了肝炎重症化的进程。 | 郭林生 张永东 喻植群 汪由坤 郝连杰 Theilmann L 侯干曾 刘群 | 1992 | 同济医科大学学报1992，21，3： | 6 |
| 3 | 为恶意、良性的胆汁的苛评的治疗的充分盖住的自我可扩充的金属 stents显示文摘 AIM:To present a series of covered self-expandable metal stents(CSEMS) placed for different indications and to evaluate the effectiveness,complications and extractability of these devices.METHODS:We therefore retrospectively reviewed the courses of patients who received CSEMS due to malignant as well as benign biliary strictures and postsphincterotomy bleeding in our endoscopic unit between January 2010 and October 2011.RESULTS:Twenty-six patients received 28 stents due to different indications(20 stents due to malignant biliary strictures,six stents due to benign biliary strictures and two stents due to post-sphincterotomy bleeding).Biliary obstruction was relieved in all cases,regardless of the underlying cause.Hemostasis could be achieved in the two patients who received the stents for this purpose.Complications occurred in five patients(18%).Two patients(7%) developed cholecystitis,stents dislocated/migrated in other two patients(7%),and in one patient(3.6%) stent occlusion was documented during the study period.Seven stents were extracted endoscopically.Removal of stents was easily possible in all cases in which it was desired using standard forceps.Twelve patients underwent surgery with pylorus preserving duodenopancreatectomy.In all patients stents could be removed during the operation without difficulties.CONCLUSION:Despite the higher costs of these devices,fully covered self-expanding metal stents may be suitable to relief biliary obstruction due to bile duct stenosis,regardless of the underlying cause.CSEMS may also represent an effective treatment strategy of severe post-sphincterotomy bleeding,not controlled by other measures. | Ahmed Abdel Samie Stephan Dette Ulrich Vhringer Michael Stumpf Karolin Kopischke Lorenz Theilmann | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，9： | 5 |
| 4 | Design of multi-functional dual hole patterned carbon nanotube composites with superhydrophobicity and durability显示文摘关于 nanocomposites 的最当前的研究集中了于他们的体积属性,即,电,微波,热、机械的性质。在实际应用,如果内在的性质将被坚持说,象对环境污染的坚韧性那样的表面性质是批评设计考虑。这研究的目的是把 nanocomposites 的体积性质与 superhydrophobic 表面性质由印技术与提高的体积性质创造一个单个多功能的系统提供了相结合。我们报导高度传导性的 superhydrophobic nanotube 的发展合成,它直接通过印技术与一个持久的双洞模式被附加。双洞模式避免导致对物理损坏柔韧的表面的高苗条比率结构的使用。它的稳定的 superhydrophobic 性质理论上并且试验性地被描绘。由合并高方面比率碳 nanotubes (CNT ) ,双有图案的 composites 能有效地也为在低电压的形成和他们的快电的加热反应消除仍然是霜的他们的 superhydrophobic 表面压制冰的反糖衣和除去的应用被使用。另外,防护有效性(SE ) 的优异电磁的干扰(EMI ) 被达到,与曾经在文学报导的最高的价值之一。 | Sung-Hoon Park Eun-Hyoung Cho Jinseung Sohn Paul Theilmann Kunmo Chu Sunghee Lee Yoonchul Sohn Dongouk Kim Byunghoon Kim | 2013 | Nano Research2013，6，6： | 4 |
| 5 | Mapping of bovine prolacfin andrhodopsin genes in hybrid somatic cells显示文摘 | HALLERMAN E M THEILMANN J L BECKMANN J S | 1988 | Anim Genet1988，19，： | 1 |
| 6 | Hepatitis B vires nucleic acids associated with human peripheral blood mononuclear cells do not originate from replicating virus显示文摘 | Kock J Theilmann L Galle P | 1996 | Hepatology1996，23，3： | 1 |
| 7 | The baculovirus transcriptional transactivator A produces multiple productsby internal initiation of translation 显示文摘 | Theilmann DA Wills LG Bosch B J | 2001 | Virology2001，290，2： | 1 |
| 8 | Mapping of bovine prolactin andrhodopsin genes in hybrid somatic cells显示文摘 | HALLERMAN E M THEILMANN J L BECKMANN J S | 1988 | Anita Genet1988，19，： | 1 |
| 9 | Proteomics analysis of Trichoplusia ni midgut epithelial cell brush border membrane vesicles显示文摘The insect midgut epithelium is composed of columnar, goblet, and regenerative cells. Columnar epithelial cells are the most abundant and have membrane protrusions that form the brush border membrane (BBM) on their apical side. These increase surface area available for the transport of nutrients, but also provide opportunities for interaction with xenobiotics such as pathogens, toxins and host plant allelochemicals. Recent improvements in proteomic and bioinfbrmatics tools provided an opportunity to determine the proteome of the T. ni BBM in unprecedented detail. This study reports the identification of proteins from BBM vesicles (BBMVs) using single dimension polyacrylamide gel elec? trophoresis coupled with multi-dimensional protein identification technology. More than 3000 proteins were associated with the BBMV of which 697 were predicted to possess either a signal peptide, at least one transmembrane domain or a GPI-anchor signal. Of these, bioinfbrmatics analysis and manual curation predicted that 185 may be associated with the BBMV or epithelial cell plasma membrane. These are discussed with respect to their predicted functions, namely digestion, nutrient uptake, cell signaling, development, cell-cell interactions, and other functions. We believe this to be the most detailed proteomic analysis of the lepidopteran midgut epithelium membrane to date, which will provide information to better understand the biochemical, physiological and pathological processes taking place in the larval midgut. | Muhammad Afzal Javed Cathy Coutu David A. Theilmann Martin A. Erlandson Dwayne D. Hegedus | 2019 | Insect Science2019，26，3： | 1 |
| 10 | Akutes H?moperitoneum bei einer spontanen Tumorruptur als Erstmanifestation eines hepatozellul?ren Karzinoms显示文摘 | A Abdel Samie G Otto L Theilmann | 2007 | Z Gastroenterol2007，，07： | 1 |
| 11 | On the classification and nomenclature of baculoviruses: A proposal for revision显示文摘 | J. A. Jehle G. W. Blissard B. C. Bonning J. S. Cory E. A. Herniou G. F. Rohrmann D. A. Theilmann S. M. Thiem J. M. Vlak | 2006 | Archives of Virology2006，，： | 1 |
| 12 | Detection of PreS1 proteins in serum and liver of HbsAg -Potive patients:A new marker for hepatitis B virus infection显示文摘 | Theilmann L Klinkert MQ Gmelin K | 1986 | Hepatology1986，6，2： | 1 |
| 13 | Early brain swelling in acute hypoxia显示文摘 | Dubowitz DJ Dyer EAW Theilmann RJ | 2009 | Appl Physiol2009，107，： | 1 |
| 14 | Analysis of the in-sect os-d-like gene family显示文摘 | WANNER K W WILLIS L G THEILMANN D A | 2004 | Journal of Chemical Ecology2004，30，5： | 1 |
| 15 | Pre-S1 proteins in sera of patients positive for HBsAg and antibodies to hepatitis delta virus显示文摘 | Theilmann L Gmelin K Tapalaga D | 1987 | Hepatogastroenterology1987，34，2： | 1 |
| 16 | AcMNPV ac143(odv-e18) is essential for mediating budded virus production and is the 30th baculovirus core gene显示文摘 | McCarthy C B Theilmann D A | 2008 | Virology2008，375，1： | 1 |
| 17 | Biliary tract strictures after orthotopic liver transplantation: dianosis and management 显示文摘 | Theilmann L Kuppers B Kadmon M | 1994 | Endoscopy1994，26，： | 1 |
| 18 | High-resolution diffusion imaging with DIFRAD-FSE (diffusion-weighted radial acquisition of data with fast spin-echo) MRI显示文摘 | Trouard TP Theilmann RJ Altbach MI | 1999 | Magn Reson Med1999，42，1： | 1 |
| 19 | Peripheral blood leukocytes serve as a possible extrahepatic site for hepatitis C virus replication显示文摘 | Muller HM Pfaff E Goeser T Kallinowski B Solbach C Theilmann L | | 0，，： | 1 |
| 20 | Acute haemopentoneum due to spontaneous tomeur repture as first manifestation of hepatocellular careinoma显示文摘 | Abdel Samie A Otto G Theilmann L | 2007 | Z Gastnoenterol2007，45，7： | 1 |
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