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    题名 作者 年代 出处 被引量
1MORN3:MEIG1的分子伴侣在小鼠生精细胞中的表达显示文摘哺乳动物精子发生由细胞发育和分化的精细过程组成。减数分裂基因1(MEG1)在调节精子发生过程中起着重要作用。为探讨MEIGl的作用机制,采用酵母双杂交筛选出可能与MEIG1发生作用的多个蛋白,OJMORN3蛋白。通过制备全长MORN3蛋白N端的特异性多克隆抗体,分别在体外和体内研究MORN3的表达和定位。免疫荧光染色转染CHO细胞显示,MORN3定位在整个包浆。体内实验证实25kDa的MORN3蛋白仅在小鼠睾丸组织中表达,且主要在出生后20天开始表达,即主要表达于精子发生的第三阶段生精细胞变态期。在从成年野生型小鼠分离的混合睾丸细胞的整个生精细胞变态期,MORN3均表达于顶体,在长形精子期该蛋白同时也在精子领表达。在Meig—J基因敲除小鼠中,MORN3总体表达水平和在顶体中的定位没有改变,但在精子领的表达显著降低。以上研究表明MORN3作为MEIGl蛋白的分子伴侣,可能是精子发生过程的另一个重要调节因子。Ling Zhang Xue-Jun Shang Hong-Fei Li Yu-Qin Shi Wei Li Maria E Teves Zhi-Qiong Wang Gao-Feng Jiang Shi-Zhen Song Zhi-Bing Zhang 2015Asian Journal of Andrology2015,17,1:3
2altered Association of Protein Tyrosine Kinases with Postsynaptic Densities after Transient Cerebral Ischcmiain the Rat Brain显示文摘Cheung H H Takagi N Teves L 2000J Cereb Blood Flow Metab2000,20,3:1
3Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain显示文摘Cook D J Teves L Tymianski M 2012Nature2012,483,7388:1
4Activation Of human medial prefrontal cortex during autonomic responses to hypoglycemia显示文摘Teves D Videen TO Cryer PE 2004Proc Natl Acad Sci USA2004,101,:1
5Cloning and expression of a functional estrogen recep- tor-α from African catfish (Clarias gariepinus) pitui- tary 显示文摘Teves A C C Granneman J C M Van Dijk W 2003J Mol Endocrinol2003,30,:1
6Altered association of protein tyrosine kinases with postsynaptic densities after transient cerebral ischemiain the rat brain显示文摘Cheung HH Takagi N Teves L Logan R Wallace MC Gurd JW 2000J Cereb Blood Flow Metab2000,20,3:1
7Treatment of stroke with a PSO - 95 inhibitor in the gyrencephalic primate brain显示文摘Cook OJ Teves L 2012Nature2012,483,:1
8Cloning and spatiotemporal expression of the follicle-stimulating hormone β subunit complementary DNA in the African Catfish (Clarias gariepinus)显示文摘Vischer H F Teves A C Ackermans J C M 0,,04:1
9Altered interaction between PSD-95 and the NMDA receptor following transient global ischemia显示文摘 Logan R Teves L 2000J Neurochem2000,74,1:1
10Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain 显示文摘Tymianski M Cook DJ Teves L 2012Nature2012,483,7388:1
11Dissecting complex physiological functions through the use ofmolecular quantitative genetics显示文摘PRIOUL J L S teve Q Mathide C 1997J Exp Bot1997,48,:1
12Altered association of protein tyrosine kinases wit post-synaptic densities after transient cerebral ischemia in the rat brain 显示文摘Cheung HH Takagi N Teves L 2000J Cereb Blood Flow Metab2000,20,3:1
13Altered interaction between PSD 95 and the NMDA receptor following transient global ischemia显示文摘Takagi N Logan R Teves L 2000J Neurochem2000,74,1:1
14Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia显示文摘Sun HS Jackson MF Martin LJ Jansen K Teves L Cui H 2009Nat Neurosci2009,12,10:1
15Human sperm pattern of movement during chemotactic 'e-orientation towards a progesterone source显示文摘人的精子可以趋化现象地由跟随引诱剂分子的一个增加的坡度发现卵。尽管人的精子被观察了显示出趋化性的几个生理的特征,运动的趋化性的模式一直不是容易的描述。然而,当回到引诱剂来源时,趋化性的房间可以被识别,是明显的。这研究向孕酮来源在趋化性的重取向期间描绘人的精子的运动的模式,它是一个生理的引诱剂候选人。借助于 videomicroscopy 和图象分析,当精子向孕酮的趋化性的集中的来源回来了,运动的一个趋化性的模式被识别(10   pmol l −1) 。作为它的原来的路径的继续,首先,精子与线性运动从孕酮来源游走然后与能被增加的速度描绘并且减少的一个过渡运动回头线性。这精子行为可以向孕酮来源自己帮助精子到使适应并且可以被用来识别在一给定的时间正在经历趋化性的很少房间。Cecilia Soledad Blengini Maria Eugenia Teves Diego Rafael Ufiates Hetor Alejandro Guidobaldi LauraVirginia Gatica Laura Cecilia Giojalas 2011Asian Journal of Andrology2011,13,5:1
16Modulation of NMDAR Subunit Ex-pression by TRPM2 Channels Regulates Neuronal Vulnerability to Is-chemic Cell Death显示文摘Alim I Teves L Li R 2013J Neurosci2013,33,17:1
17Doxorubicin, DNA torsion, and chromatin dynamics 显示文摘Yang F Teves SS Kemp CJ 2014Biochim Biophys Acta2014,1845,1:1
18ABC of clinical electrocardiography:atrial arrhythmias显示文摘Teve Goodacre Richard Irons 2002BMJ2002,324,:1
19TricIosan-loaded poloxamine micelles for enhanced topical antibacterial activity against biofilm显示文摘Chiappetta D A Degrossi J Teves S 2008Eur J Pharm Biopharm2008,69,2:1
20Sperm-associated antigen 6 (SPAG6) deficiency and defects in ciliogene- sis and cilia function: polarity, density, and beat显示文摘Teves ME Sears PR Li W 2014PloS One2014,9,10:1
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