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| 1 | Early palliative care for patients with metastatic non-small-cell lung cancer显示文摘Comments This landmark article demonstrates that integration of early palliative care with standard oncologic practice shortly after diagnosis may improve quality of life,mood,and overall survival for adults with advanced non-small-cell lung cancer(NSCLC).If validated,these findings could support a paradigm shift in the care of adults with metastatic NSCLC and possibly patients with other tumor types characterized by short survival and high symptom burden. | Temel JS Greer JA Muzikansky A Gallagher ER Admane S Jackson VA Dahlin CM Blinderman CD Jacobsen J Pirl WF Billings JA Lynch TJ | 2010 | 中国肺癌杂志2010，13，9： | 165 |
| 2 | Modeling of the Prediction of Densification Behavior of Powder Metallurgy Al–Cu–Mg/B_4C Composites Using Artificial Neural Networks显示文摘Al–Cu–Mg/B4 Cp metal matrix composites with reinforcement of up to 20 wt% were produced using the powder metallurgy technique. The effects of reinforcement ratio, reinforcement size, milling time, and compact pressure on the density and porosity of the composites reinforced with 0, 5, 10, and 20 wt% B4 C particles were studied. Moreover, an artificial neural network model has been developed for the prediction of the effects of the manufacturing parameters on the density and porosity of powder metallurgy Al–Cu–Mg/B4 Cp composites. This model can be used for predicting the densification behavior of Al–Cu–Mg/B4 Cp composites produced under reinforcement of different sizes and amounts with various milling times and compact pressures. The mean absolute percentage error for the predicted values did not exceed1.6%. | Temel Varol Aykut Canakci Sukru Ozsahin | 2015 | Acta Metallurgica Sinica(English Letters)2015，28，2： | 3 |
| 3 | Polymersomes scalably fabricated via flash nano- precipitation are non-toxic in non-human primates and associate with leukocytes in the spleen and kidney following intravenous administration显示文摘 | Sean D. Allen Yu-Gang Liu Sharan Bobbala Lei Cai Peter I. Hecker Ryan Temel Evan A. Scott | 2018 | Nano Research2018，11，10： | 3 |
| 4 | 热处理对Zn−40Al−2Cu−2Si合金力学性能和磨损性能的影响显示文摘为了研究热处理对Zn−40Al−2Cu−2Si合金力学性能和磨损性能的影响,采用不同工艺对其进行热处理,包括均匀化后空冷(H1)、均匀化后炉冷(H2)、稳定化(T5)和淬火−时效(T6和T7)。通过金相、力学实验和磨损实验,研究不同热处理工艺对该合金力学性能和摩擦学性能的影响,并于SAE 65青铜进行对比。磨损实验使用环块式实验装置。结果表明,采用H1和T6热处理可提高合金的硬度、抗拉强度和抗压强度,除T6热处理外的其他热处理均可提高合金的断裂伸长率。经H1、T5和T6热处理后,合金的摩擦因数和磨损量减小,其中T6热处理后合金的摩擦因数和磨损量最低。因此,T6热处理为该合金应用于14 MPa压力下润滑摩擦的最佳工艺。与青铜相比,铸态和热处理态的Zn−40Al−2Cu−2Si合金磨损量较低、耐磨性较高。 | Temel SAVAŞKAN Zeki AZAKLI Ali Paşa HEKÌMOĞLU | 2021 | Transactions of Nonferrous Metals Society of China2021，31，9： | 3 |
| 5 | Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis显示文摘 | Rayner Katey J Sheedy Frederick J Esau Christine C Hussain Farah N Temel Ryan E Parathath Saj van Gils Janine M Rayner Alistair J Chang Aaron N Suarez Yajaira Fernandez-Hernando Carlos Fisher Edward A Moore Kathryn J | 2011 | Journal of Clinical Investigation2011，，7： | 2 |
| 6 | A new framework for reverse cholesterol transport: Non-biliary contributions to reverse cholesterol transport显示文摘Reduction of low-density lipoprotein-cholesterol through statin therapy has only modestly decreased coronary heart disease (CHD)-associated mortality in developed countries, which has prompted the search for alternative therapeutic strategies for CHD. Major efforts are now focused on therapies that augment high-density lipoprotein (HDL)-mediated reverse cholesterol transport (RCT), and ultimately increase the fecal disposal of cholesterol. The process of RCT has long been thought to simply involve HDL-mediated delivery of peripheral cholesterol to the liver for biliary excretion out of the body. However, recent studies have revealed a novel pathway for RCT that does not rely on biliary secretion. This nonbiliary pathway rather involves the direct excretion of cholesterol by the proximal small intestine. Compared to RCT therapies that augment biliary sterol loss, modulation of non-biliary fecal sterol loss through the intestine is a much more attractive therapeutic strategy, given that excessive biliary cholesterol secretion can promote gallstone formation. However, we are at an early stage in understanding the molecular mechanisms regulating the non-biliary pathway for RCT, and much additional work is required in order to effectively target this pathway for CHD prevention. The purpose of this review is to discuss our current understanding of biliary and nonbiliary contributions to RCT with particular emphasis on the possibility of targeting the intestine as an inducible cholesterol secretory organ. | Ryan E Temel J Mark Brown | 2010 | World Journal of Gastroenterology2010，16，47： | 2 |
| 7 | Air- way inflammatory markers in chronic obstructive pulmonary disease patients and healthy smokers 显示文摘 | Hacievliyagil SS Mutlu LC Temel L | 2013 | Niger J Clin Pract2013，16，1： | 1 |
| 8 | Hepatic Niemann-Pick Cl-like 1 regulates biliary cholesterol concentration and is a target of ezetimi- be显示文摘 | Temel R E Tang W Ma Y | 2007 | J Clin Invest2007，117，7： | 1 |
| 9 | Apolipoprotein A-I is necessary for the in vivo formation of high density lipoprotein competent for scavenger receptor BI-mediated cholesterol ester-selective uptake显示文摘 | Ryan E Temel Rosemary L Walzem Carole L | 2002 | J Biol Chem2002，277，26： | 1 |
| 10 | Effects of citicoline used alone and in combination with mild hypothermia on apoptosis induced by focal cerebral ischemia in rats显示文摘 | Sahin S Alkan T Temel SG | 2010 | J Clin Neurosci2010，17，2： | 1 |
| 11 | Inhibition of 5-HT neu- ron activity and induction of depressive-like behavior by high-fre- quency stimulation of the sub-thalamic nucleus 显示文摘 | Temel Y Boothman LJ Blokland A | 2007 | Proc Natl Acad Sci USA2007，104，17： | 1 |
| 12 | Experimental and Numer- ical Investigation of Brace Configuration Effects on Steel Struc- tures显示文摘 | Temel Tiirker Alemdar Bayraktar | 2011 | Journal of Constructional Steel Research2011，67，： | 1 |
| 13 | MR Imaging Techniques for Pancreas显示文摘 | Temel Tirkes Christine O. Menias Kumaresan Sandrasegaran | 2012 | Radiologic Clinics of North America2012，，3： | 1 |
| 14 | Compared with aeyl-CoA: cholesterol acyltransferase (ACAT) 1 and lecithin : cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol显示文摘 | Temel RE Gebre AK Parks JS | 2003 | J Biol Chem2003，278，47： | 1 |
| 15 | Hemodynamics in coro-nary artery bypass surgery: effects of intraoperative dexmedetomi- dine administration 显示文摘 | Kabukcu IIK Sahin N Temel Y | 2011 | Anaesthesist2011，60，5： | 1 |
| 16 | beta - human chorionic gonado- tropin assay in vaginal washing fluid for the accurate diagnosis of prema- ture rupture of membranes during late preg,ancy显示文摘 | Temel O Cogendez E Seleuk S | 2013 | J Turk Ger Gyne- col Assoc2013，14，4： | 1 |
| 17 | Airway inflammatory markers in chronic obstructive pulmonary disease and healthy smokers显示文摘 | Hacievliyagil S S Mutlu L C Temel J | 2013 | Niger J Clin Pract2013，16，1： | 1 |
| 18 | Biliary sterol secretion is notrequired for macrophage reverse cholesterol transport 显示文摘 | Temel RE Sawyer JK Yu L | 2010 | Cell Metab2010，12，1： | 1 |
| 19 | One-pot synthesis of water-soluble polymeric photoinitiator via thioxanthonation and sulfonation process 显示文摘 | TEMEL G ARSU N | 2009 | Journal of Photochemistry and Photobiology A: Chemistry2009，202，： | 1 |
| 20 | Hemodynamics in earonary artery bypass surgery: effects of intraoperative dexmedetomidine administration 显示文摘 | KARAKAYA KABUKCU H SAHIN N TEMEL Y | 2011 | Anaesthesist2011，60，5： | 1 |
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