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| 1 | Effect of Helicobacter pylori on gastric epithelial cells显示文摘The gastrointestinal epithelium has cells with features that make them a powerful line of defense in innate mucosal immunity. Features that allow gastrointestinal epithelial cells to contribute in innate defense include cell barrier integrity, cell turnover, autophagy, and innate immune responses. Helicobacter pylori(H. pylori) is a spiral shape gram negative bacterium that selectively colonizes the gastric epithelium of more than half of the world's population. The infection invariably becomes persistent due to highly specialized mechanisms that facilitate H. pylori 's avoidance of this initial line of host defense as well as adaptive immune mechanisms. The host response is thus unsuccessful in clearing the infection and as a result becomes established as a persistent infection promoting chronic inflammation. In some individuals the associated inflammation contributes to ulcerogenesis or neoplasia. H. pylori has an array of different strategies to interact intimately with epithelial cells and manipulate their cellular processes and functions. Among the multiple aspects that H. pylori affects in gastric epithelial cells are their distribution of epithelial junctions, DNA damage, apoptosis, proliferation, stimulation of cytokine production, and cell transformation. Some of these processes are initiated as a result of the activation of signaling mechanisms activated on binding of H. pylori to cell surface receptors or via soluble virulence factors that gain access to the epithelium. The multiple responses by the epithelium to the infection contribute to pathogenesis associated with H. pylori. | Shatha Alzahrani Taslima T Lina Jazmin Gonzalez Irina V Pinchuk Ellen J Beswick Victor E Reyes | 2014 | World Journal of Gastroenterology2014，20，36： | 15 |
| 2 | Immune evasion strategies used by Helicobacter pylori显示文摘Helicobacter pylori(H. pylori) is perhaps the most ubiquitous and successful human pathogen, since it colonizes the stomach of more than half of humankind. Infection with this bacterium is commonly acquired during childhood. Once infected, people carry the bacteria for decades or even for life, if not treated. Persistent infection with this pathogen causes gastritis, peptic ulcer disease and is also strongly associated with the development of gastric cancer. Despite induction of innate and adaptive immune responses in the infected individual, the host is unable to clear the bacteria. One widely accepted hallmark of H. pylori is that it successfully and stealthily evades host defense mechanisms. Though the gastric mucosa is well protected against infection, H. pylori is able to reside under the mucus, attach to gastric epithelial cells and cause persistent infection by evading immune responses mediated by host. In this review, we discuss how H. pylori avoids innate and acquired immune response elements, uses gastric epithelial cells as mediators to manipulate host T cell responses and uses virulence factors to avoid adaptive immune responses by T cells to establish a persistent infection. We also discuss in this review how the genetic diversity of this pathogen helps for its survival. | Taslima T Lina Shatha Alzahrani Jazmin Gonzalez Irina V Pinchuk Ellen J Beswick Victor E Reyes | 2014 | World Journal of Gastroenterology2014，20，36： | 7 |
| 3 | CagA-Dependent Downregulation of B7-H2 Expression on Gastric Mucosa and Inhibition of Th17 Responses during Helicobacter pylori Infection显示文摘 | Taslima T. Lina Irina V. Pinchuk Jennifer House Yoshio Yamaoka David Y. Graham Ellen J. Beswick Victor E. Reyes | 2013 | The Journal of Immunology2013，，7： | 1 |
| 4 | Microparticle characterization using digital holography显示文摘 | EMMANOUIL Darakis TASLIMA Khanam ARVIND Rajendran | 2010 | Chemical Engineering Science2010，65，2： | 1 |
| 5 | CagA-Dependent Downregulation of B7-H2 Expression on Gastric Mucosa and Inhibition of Th17 Responses during Helicobacter pylori Infection显示文摘 | Taslima T. Lina Irina V. Pinchuk Jennifer House Yoshio Yamaoka David Y. Graham Ellen J. Beswick Victor E. Reyes | 2013 | The Journal of Immunology2013，，7： | 1 |
| 6 | Microparticle characterization using digital holography显示文摘 | Darakis Emmanouil Khanam Taslima Rajendran Arvind | 2010 | Chem Eng Sci2010，65，2： | 1 |
| 7 | Development of chemometric model for characterization of non-wood by FT-NIR data显示文摘In this study,a model for prediction of lignocellulose components of agricultural residues has been developed with Fourier Transformed Near Infrared(FT-NIR)spectroscopy data.Two calibration techniques(Principal Component Regression(PCR)and Partial Least Square Regression(PLSR))were assessed for prediction of lignin,holocellulose,α-cellulose,pentosan and ash,and found the PLSR better for lignin,holocellulose andα-cellulose.The PCR also produced better results for quantification of pentosan and ash.Spectral range(7000-5000 cm^(-1))showed more informative than other parts of the spectral data.The PLSR showed maximum value of R^(2)(R^(2)=0.91%)for prediction of holocellulose.For the prediction of pentosan,the PCR was better(R^(2)=0.68%).The PCR also showed better results(R^(2)=86%)for quantification of ash.To determine amount of lignin,the PLSR was the best(R^(2)=0.83%)when the spectral data were de-trained and smoothed with Savitzky-Golay(S-G)filtering simultaneously.For prediction ofα-cellulose,the PLSR was the best model(R^(2)=0.94%)when the data were pretreated with mean normalization.Considering the best alternatives inNear Infrared(NIR)data preprocessing and calibration techniques,methods for quantification of lignocellulose components of agricultural residues have been developed which is rapid,cost effective,and less chemical intensive and easily usable in pulp and paper industries and pulp testing laboratories. | Mohammad Nashir Uddin Taslima Ferdous Zahidul Islam M.Sarwar Jahan M.A.Quaiyyum | 2020 | Journal of Bioresources and Bioproducts2020，5，3： | 0 |
| 8 | A Comparative Study on Feeding Practice and Nutrition Status among 6-23 Months Age Children显示文摘 | Taslima Khatun Md Shahjahan Matabbar Manika Rani Sarker Asad-Ud-Daula Asirul Hoque | 2014 | Journal of Life Sciences2014，8，8： | 0 |
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