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| 1 | Identification and Validation of an Immune-related Prognostic Signature for Hepatocellular Carcinoma显示文摘Background and Aims:The immune system plays vital roles in hepatocellular carcinoma(HCC)initiation and progression.The present study aimed to construct an immune-gene related prognostic signature(IRPS)for predicting the prognosis of HCC patients.Methods:Gene expression data were retrieved from The Cancer Genome Atlas database.The IRPS was established via least absolute shrinkage and selection operator(LASSO)and multivariate Cox regression analysis.The prognostic values of the IRPS were further validated using the International Cancer Genome Consortium(ICGC)dataset.Results:A total of 62 genes were identified as candidate immune-related prognostic genes.According to the results of Lasso and multivariate Cox regression analysis,we established an IRPS and confirmed its stability and reliability in the ICGC dataset.The IRPS was significantly associated with advanced clinicopathological characteristics.Both Cox regression analyses revealed that the IRPS could be independent risk factors influencing prognosis of HCC patients.The relationships between the IRPS and infiltration of immune cells demonstrated that the IRPS was associated with immune cell infiltration.Furthermore,a nomogram was constructed to estimate the survival probability of HCC patients.Conclusions:The IRPS was effective for predicting prognosis of HCC patients,which might serve as novel prognostic and therapeutic biomarkers for HCC. | Xinxin Xia Ping Tang Hui Liu Yuejun Li | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 3 |
| 2 | Protein identification and mRNA analysis of phyto-chrome-regulated genes in Arabidopsis under red light显示文摘Phytochromes are a family of plant photoreceptors that mediate physiological and developmental re- sponses to red and far-red light. According to the affymetrix ATH1 microarray, phytochrome A (phyA) and phytochrome B (phyB) together play a key role in transducing the Rc signals to light-responsive genes. In order to select those red light-responsive genes associated with phyA or phyB, a proteomic approach based on two-dimensional gel electrophoresis (2-DE) was used to compare the protein ex- pression patterns of the phyAphyB double mutant and the wild type of Arabidopsis thaliana (col-4) which grew under constant red light conditions for 7 d. Thirty-two protein spots which exhibited dif- ferences in protein abundance were identified by matrix-assisted laser desorption/ionization-time of flight/time of flight mass spectrometry. The expression of ten genes corresponding to ten protein spots was analyzed by a semiquantitative reverse transcription-polymerase chain reaction. Two of the ten genes were confirmed by quantitative PCR (Q-PCR). The results showed that phytochromes may exert their function by regulating mRNA or protein expressions. Proteomic analysis may provide a novel pathway for identifying phytochrome-dependent genes. | LI Xu*, YANG YueJun*, LI Yan, WANG Jie, XIAO XiaoJuan, GUO XinHong, TANG DongYing & LIU XuanMing Bioenergy and Biomaterial Research Center, College of Life Science and Biotechnology, Hunan University, Changsha 410082, China. | 2009 | Science China(Life Sciences)2009，52，4： | 2 |
| 3 | Comparative proteomics analysis of light responses in cryptochromel-304 and Columbia wild-type 4 of Arabidopsis thaliana显示文摘 | Yuejun Yang Yan Li Xu Li Xinhong Guo Xiaojuan Xiao Dongying Tang Xuanming Liu | 2008 | Acta Biochimica et Biophysica Sinica2008，40，1： | 2 |
| 4 | Study on design ground motion parameters and seismic fortification criteria of one oil field in the Bohai Sea 显示文摘 | Peng Yanju Lv Yuejun Tang Rongyu | 2007 | Earthquake Engineering and Engineering Vibration2007，27，4： | 1 |
| 5 | Environmental Capital,Negative Externality and Carbon Finance Innovation显示文摘In the context of global climate change,the internalization of negative externality,which is brought about by the traditional mode of economic growth,has become an inevitable choice.In order to achieve the internalization,it is necessary to make innovations on the market mechanism and system,find the value of environmental capital,establish a new mode of economic growth based on environmental capital,and then transform the environmental capital,an exogenous factor of economic growth,into an endogenous factor.Of this,the key of market mechanism and system innovation is the financial innovation that is based on environmental capital and negative externality;the government defines the initial property right of environmental resources and establishes environment energy trading market,so as to guide enterprises to trade environmental resources(represented by carbon emission permit trading) based on the Clean Development Mechanism,and to vigorously develop environmental finance and carbon finance. | Tang Yuejun Li Defu | 2011 | Chinese Journal of Population,Resources and Environment2011，9，2： | 1 |
| 6 | Single pulse deposition of Pd-Ag alloy nanowires on highly oriented pyrolytic graphite : A mechanistic assessment 显示文摘 | Tang Lili Yu Gang Ouyang Yuejun | 2008 | Electrochimica Acta2008，53，8： | 1 |
| 7 | The Governance Model for Entrepreneurial Enterprises:A Study Based on Dynamic Ownership Governance Platform显示文摘When human capital becomes the most important strategic capital,an entrepreneurial enterprise has to reform and innovate its corporate governance around human capital and its dynamism so as to acquire the capacity of sustainable endogenous growth.This article is intended to discuss the meaning and adaptability of Huawei’s characteristic systems and mechanisms and then proceeds to introduce the general design of entrepreneurial enterprises'dynamic ownership governance platform and the possible effect of corporate governance.Subject to existing Chinese laws and regulations and with full consideration of the dynamics of human capital,this article recommends an entrepreneurial enterprise to set up a dynamic ownership governance platform,innovate and optimize its corporate governance structure and relevant mechanisms and promote the gradual socialization of its founder/founding team’s rights to earnings,control and management;then put in place scientific and proper counterbalance mechanisms in accordance with the principle of separation of powers and incentive compatibility,reform its selection of managing staff and introduce market mechanisms to promote fair competition and dynamic incentive compatibility between its founder/founding team and other key stakeholders.This article is meant to facilitate an entrepreneurial enterprise to turn to socialization corporate governance,and acquire the motivation and gradually form the capacity for endogenous growth. | TANG Yuejun ZUO Jingjing | 2022 | Frontiers of Business Research in China2022，16，1： | 0 |
| 8 | Soft Soil Site Characterization on the Coast of Yantai and Its Effect on Ground Motion Parameters显示文摘According to the Chinese GB50011-2001 code and the recommended provisions of FEMA-NEHRP and EUROCODE 8, by using shear wave velocity and borehole data, the site classification is evaluated for a typical soft soil site on the Yantai seacoast. The site seismic ground motion effect is analyzed and the influence of the coastal soil on design ground motion parameters is discussed. The results show that the brief site classification can not represent the real conditions of a soft soil site; the soft soil on the coast has a remarkable impact on the magnitude and spectrum of ground motion acceleration. The magnification on peak acceleration is bigger, however, due to the nonlinear deformation of the soil. The magnification is reduced nonlinearly with the increase of input ground motion; the spectrum is broadened and the characteristic period elongated on the soft soil site. | Lü Yuejun Tang Rongyu Peng Yanju | 2005 | Earthquake Research in China2005，19，2： | 0 |
| 9 | Statistical Analysis of the Dynamic Parameters of Silty Clay in the Beijing Area显示文摘Soil dynamic parameters,including dynamic shear modulus ratio and damping ratio,have important effects on the results of layered soil earthquake response. In this paper,the mean parameter values of silty clay in different depths are obtained after statistical analysis of the experimental soil dynamic data from 20 recent site seismic safety evaluation reports in the Beijing area. Furthermore,based on two typical engineering sites,the influence of four different soil dynamic parameters,the statistic mean values,experimental values, values recommended by Yuan Xiaoming,and the values recommended in the code for seismic safety evaluation of engineering sites( DB001-94) are analyzed. The result shows that mean statistical values are applicable to seismic safety evaluation work in the Beijing area,especially for some inter-layered silty clays whose undisturbed soil samples are hard to obtain. | Shi Chunhua Lu Yuejun Peng Yanju Tang Rongyu | 2010 | Earthquake Research in China2010，24，1： | 0 |
| 10 | A self-healing coating based on facile pH-responsive nanocontainers for corrosion protection of magnesium alloy显示文摘The preparation of pH-responsive nanocontainers by typical silane modification of the mesoporous silica nanoparticle(MSN)surface is usually high-cost,complex,and time-consuming,which remains a great challenge for effective corrosion protection of magnesium alloy.Here,a new strategy to construct pH-responsive nanocontainers(MSN-MBT@LDH)is demonstrated.The nanocontainers consist of corrosion inhibitor(2-mercaptobenzothiazole,MBT)loaded MSN core and layered double hydroxide(LDH)nanosheet shell serving as gatekeepers.The successful loading of MBT and encapsulation by LDH nanosheets were confirmed by a series of characterization such as scanning transmission electron microscopy coupled with energy dispersive X-ray spectroscopy(STEM-EDS)and N2 adsorption/desorption isotherms.The pH-responsive feature of the nanocontainers was demonstrated by determination of the MBT concentration in buffer solutions with different pH values.A smart corrosion protection system on Mg alloy is obtained by incorporating the synthesized nanocontainers into a self-assembled nanophase particle(SNAP)coating.The electrochemical tests and visual observations show that the hybrid coating has the best barrier properties and robustness in corrosion protection in NaCl corrosive solutions in comparison with the control coatings.The present method simplifies the synthesis processes of nanocontainers and eliminates the potential detrimental effect of excess gatekeepers on the coating.The findings provide new insights into the preparation of scalable nanocontainers.The self-healing coatings are expected to have widespread applications for corrosion protection of Mg alloy and other metals. | Yuejun Ouyang Lin-Xin Li Zhi-Hui Xie Lili Tang Fuhui Wang Chuan-Jian Zhong | 2022 | Journal of Magnesium and Alloys2022，10，3： | 0 |
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