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| 1 | Necessity and indications of invasive treatment for Budd-Chiari syndrome显示文摘BACKGROUND:The development of collaterals in Budd-Chiari syndrome has been described and these collaterals play an important role in the presentation of this disease.These collaterals are diagnostic and their use in management strategy has never been evaluated.This study aimed to investigate the indications,feasibility and necessity of invasive treatment for patients with Budd-Chiari syndrome and to determine whether such a strategy is necessary for optimal management.METHODS:Twenty-nine patients who had been treated at our unit were enrolled in this study.Based on physical and biochemical examination,and hemodynamic compensation by collaterals,18 patients underwent radiological intervention (group A),while the other 11 had no invasive treatment (group B).The related hemodynamic parameters were acquired when percutaneous angiography was performed.RESULTS:In group A,all patients underwent successfully inferior vena cava (IVC) balloon angioplasty with or without stenting.Four patients also underwent hepatic vein angioplasty.In these patients,the mean IVC pressure before and after treatment was statistically different (29.3±9.2 vs 15.1±4.6 mmHg,P<0.01).The mean IVC pressure was much lower in group B than in group A (12.9±2.4 vs 29.3±9.2 mmHg,P<0.01),but there was no difference from that of the patients after radiological treatment (12.9±2.4 vs 15.1±4.6 mmHg,P>0.05).Median follow-up was 32.3 months (mean 21.3 months;range 3-61 months).In the course of follow-up,the patients in group A survived with good systemic status except for re-stenosis in one patient who underwent re-canalization of the IVC.In group B,10 patients had good systemic status except one patient who had a meso-caval shunt because of deterioration.CONCLUSIONS:The rationale of 'early diagnosis and early treatment' is not suitable for all patients with Budd-Chiari syndrome.Satisfactory survival can be achieved in some patients without invasive treatment,who are completely compensated by rich collaterals.Nonetheless,a positive treatment procedure should be performed if the patient's situation worsens in the course of regular follow-up. | Department of General Surgery (Fu Y,Sun YL,Ma XX,Xu PQ,Feng LS,Tang Z and Luo CH),Institute of Hepatic Vascular Disease (Sun YL),Department of Radiological Intervention (Guan S and Wang ZW),First Affiliated Hospital,Zhengzhou University School of Medicine,Zhengzhou 450052,China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 10 |
| 2 | Evaluation on clinic effect of ferrous succinate treatment with iron deficiency anemia显示文摘 | CHEN LS CAO RN TANG J | 2001 | Acta Acad Med Xuzhou(in Chinese)2001，21，2： | 2 |
| 3 | Antioxidant activity of stilbene gly- coside from Polygonum multiflorum thunb in vivo 显示文摘 | Lv LS Gu XH Tang J | 2007 | Food Chem2007，104，： | 1 |
| 4 | Plasma AI340 and AI342 and Alzheimer's disease: relation to age, mortality, and risk 显示文摘 | Mayeux K Honig LS Tang MX | 2003 | Neurology2003，61，： | 1 |
| 5 | Expression of trkB,trkC in injured and regenerating retinal ganglion cell of adult rats显示文摘 | Cui Q Tang LS Hu B | 2002 | Invest Ophthalmol Vis Sci2002，43，： | 1 |
| 6 | Dynamic changes in histone acety- lation during sheep oocyte maturation 显示文摘 | Tang LS Wang Q Xiong B | 2007 | J Reprod Dev2007，53，3： | 1 |
| 7 | Risk {actors for venous thromboembolism among reproductive age women 显示文摘 | Westhoff CL Yoon LS Tang R | 2016 | J Womens Heahh2016，25，1： | 1 |
| 8 | Plasma Aβ40 and Aβ42 and Alzheimer's disease: relation to age, mortality, and risk显示文摘 | Mayeux R Honig LS Tang MX | 2003 | Neurol2003，61，9： | 1 |
| 9 | Role of Folbpl in the regional regulation of apoptosis and cell proliferation in the developing neural tube and craniofacies显示文摘 | Tang LS Santillano DR Wlodarczyk BJ Miranda RC Finnell RH | 2005 | Am J Med Genet C Semin Med Genet2005，135，1： | 1 |
| 10 | Developmental consequences of abnormal folate trans port during murine heart morphogenesis显示文摘 | Tang LS Wlodarczyk BJ Santillano DR Miranda RC Finnell RH | 2004 | Birth Defects Res A Clin Mol Teratol2004，70，7： | 1 |
| 11 | Protective effect of an endothelial lipase gene variant on coronary artery diseasein a Chinese population显示文摘 | Tang NP Wang LS Yang L | 2008 | J Lipid Res2008，49，2： | 1 |
| 12 | Neural and orofacial defects in Folpl knockout mice显示文摘 | Tang LS Finnell RH | 2003 | Birth Defects Res A Clin Mol Teratol2003，67，4： | 1 |
| 13 | Stroke and the risk of Alzheimer disease显示文摘 | Honig LS Tang MX Albert S | | 0，，： | 1 |
| 14 | Association between tumor necrosis factor-alpha promoter polymorphism and Alzheimer's disease 显示文摘 | Suk Ling Ma Nelson LS Tang Linda CW Lain | 2004 | Neurology2004，62，： | 1 |
| 15 | Modulation of murine Alzheimer pathogenesis and behavior by surgery 显示文摘 | Tang JX Mardini F Janik LS | 2013 | Ann Surg2013，257，3： | 1 |
| 16 | A statistical analysis of factors related to symptomatic cerebral vasospasm显示文摘 | Rabb CH Tang G Chin LS | 1994 | Acta Neurochir(Wien)1994，127，12： | 1 |
| 17 | Expression of trkA, trkB, and trkC in injured and regenerating retinal ganglion cells of adult rats 显示文摘 | Cui Q Tang LS Hu B | 2002 | Invest Ophthalmol Vis Sci2002，43，6： | 1 |
| 18 | Plasma Aβ40 and Aβ42 and Alzheimer's disease:relation to age,mortality,and risk显示文摘 | Mayeux K Honig LS Tang MX | 2003 | Neurology2003，61，： | 1 |
| 19 | Advanced glycation end-products induce apoptosis involving the signaling pathways of oxidative stress in bovine retinal perieytes 显示文摘 | Chen BH Jiang DY Tang LS | 2006 | Life Sci2006，79，11： | 1 |
| 20 | Association of GSTM1 and GSTT1 gene polymorphisms with coronary artery disease in relation to tobacco smoking显示文摘 | Wang LS Tang JJ Tang NP | 2008 | Clin Chem Lab Med2008，46，12： | 1 |
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